|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Heart-type fatty acid binding protein (H-FABP) as a biomarker for acute myocardial injury and long-term post-ischemic prognosis显示文摘尖锐心肌的梗塞(AMI ) 是一个威胁生活的事件。甚至与及时处理,尖锐 ischemic 心肌的损害和随后的局部缺血灌注损害(IRI ) 能仍然是困难的问题处理。除了放射学并且另外的辅助考试,适用的心脏的 biomarkers 的实验室测试为这混乱监视的早诊断和结束也是必要的。心类型丰满的酸绑定蛋白质(H-FABP ) 主要在 cardiomyocytes 内存在,最近为心肌的损害作为潜在地有希望的 biomarker 出现了。在这评论,我们在对心肌的损害和 IRI 的评价讨论 H-FABP 的敏感和特性,特别在早阶段,和它与另外的通常使用的心脏的 biomarkers 比较的长期的预示的价值,包括肌球素( Mb ),心脏的 troponin 我( cTnI ),肌酸 kinase MB ( CK-MB ),C反应的蛋白质( CRP ),肝糖 phosphorylase isoenzyme BB ( GPBB ),和高敏感的心脏的 troponin T ( hs-cTnT )。有另外的 biomarkers 的 H-FABP 的联合申请的潜力和值也被讨论。最后, H-FABP 的前景被总结;几个技术问题被讨论在临床的实践便于 H-FABP 的更宽的申请。 | Xiao-dong YE Yi HE Sheng WANG Gordon T WONG Michael G IRWIN Zhengyuan XIA | 2018 | Acta Pharmacologica Sinica2018，39，7： | 72 |
| 2 | Air quality monitoring using mobile microscopy and machine learning显示文摘Rapid,accurate and high-throughput sizing and quantification of particulate matter(PM)in air is crucial for monitoring and improving air quality.In fact,particles in air with a diameter of≤2.5μm have been classified as carcinogenic by the World Health Organization.Here we present a field-portable cost-effective platform for high-throughput quantification of particulate matter using computational lens-free microscopy and machine-learning.This platform,termed c-Air,is also integrated with a smartphone application for device control and display of results.This mobile device rapidly screens 6.5 L of air in 30 s and generates microscopic images of the aerosols in air.It provides statistics of the particle size and density distribution with a sizing accuracy of~93%.We tested this mobile platform by measuring the air quality at different indoor and outdoor environments and measurement times,and compared our results to those of an Environmental Protection Agency–approved device based on beta-attenuation monitoring,which showed strong correlation to c-Air measurements.Furthermore,we used c-Air to map the air quality around Los Angeles International Airport(LAX)over 24 h to confirm that the impact of LAX on increased PM concentration was present even at 47 km away from the airport,especially along the direction of landing flights.With its machinelearning-based computational microscopy interface,c-Air can be adaptively tailored to detect specific particles in air,for example,various types of pollen and mold and provide a cost-effective mobile solution for highly accurate and distributed sensing of air quality. | Yi-Chen Wu Ashutosh Shiledar Yi-Cheng Li Jeffrey Wong Steve Feng Xuan Chen Christine Chen Kevin Jin Saba Janamian Zhe Yang Zachary Scott Ballard Zoltán Göröcs Alborz Feizi Aydogan Ozcan | 2017 | Light(Science & Applications)2017，6，1： | 5 |
| 3 | Heavy metals in agricultural soils of the Pearl River Delta, South China显示文摘 | S.C Wong X.D Li G Zhang S.H Qi Y.S Min | 2002 | Environmental Pollution2002，，1： | 4 |
| 4 | 脂质组学改善传统危险因素预测的2型糖尿病患者的心血管事件显示文摘临床脂质测定并未显示出糖尿病或心血管病相关的脂质代谢改变的复杂性。脂质组学则能够评估可作为疾病风险潜在标志物的数百种脂质种类。方法:纳入来自糖尿病治疗和血管保护行动。 | 刘莉 叶鹏 Alshehry ZH Mundra PA Barlow CK Mellett NA Wong G McConville MJ Simes J Tonkin AM Sullivan DR Barnes EH Nestel PJ Kingwell BA Marre M Neal B Poulter NR Rodgers A Williams B Zoungas S Hillis GS Chalmers J Woodward M Meikle PJ | 2016 | 中华高血压杂志2016，24，10： | 3 |
| 5 | 新型冠状病毒肺炎及其心血管效应:流行病学研究的系统综述显示文摘少数新型冠状病毒肺炎(新冠肺炎)患者病情严重,其特征是炎症、微血管损伤和凝血障碍,可能导致心肌损伤、静脉血栓栓塞症(venous thromboembolism, VTE)和动脉闭塞事件。有心血管病危险因素或既往有心血管病的个体可能面临更大的风险。目的:评估各种环境(包括社区、疗养院和医院)中,与新冠肺炎疑似或确诊病例相关的既往存在心血管合并症的患病率。研究者还评估了疑似或确诊新冠肺炎患者随后发生心血管并发症和临床事件的性质和发生率。 | Pellicori P Doolub G Wong CM Lee KS Mangion K Ahmad M Berry C Squire I Lambiase PD Lyon A McCon-nachie A Taylor RS Cleland JG 刘青(摘译) 练桂丽(审校) | 2021 | 中华高血压杂志2021，29，5： | 3 |
| 6 | Tumor necrosis factor-α-induced protein 1 and immunity to hepatitis B virus显示文摘AIM: To compare the gene expression profile in a pair of HBV-infected twins.METHODS: The gene expression profile was compared in a pair of HBV-infected twins.RESULTS: The twins displayed different disease outcomes. One acquired natural immunity against HBV,whereas the other became a chronic HBV carrier. Eightyeight and forty-six genes were found to be up- or downregulated in their PBMCs, respectively. Tumor necrosis factor-alpha-induced protein 1 (TNF-αIP1) that expressed at a higher level in the HBV-immune twins was identified and four pairs of siblings with HBV immunity by RTPCR. However, upon HBV core antigen stimulation,TNF-αIP1 was downregulated in PBMCs from subjects with immunity, whereas it was slightly upregulated in HBV carriers. Bioinformatics analysis revealed a K+channel tetramerization domain in TNF-αIP1 that shares a significant homology with some human, mouse, and C elegan proteins.CONCLUSION: TNF-αIP1 may play a role in the innate immunity against HBV. | Marie C Lin Nikki P Lee Ning Zheng Pai-Hao Yang Oscar G Wong Hsiang-Fu Kung Chee-Kin Hui John M Luk George Ka-Kit Lau | 2005 | World Journal of Gastroenterology2005，11，48： | 3 |
| 7 | Age-related macular degeneration显示文摘 | Laurence S Lim Paul Mitchell Johanna M Seddon Frank G Holz Tien Y Wong | 2012 | The Lancet . 2012 (9827)2012，，9827： | 2 |
| 8 | Reninoma: case report and literature review显示文摘 | Lara Wong Thomas HS Hsu Mark G Perlroth Lawrence V Hofmann Claudia M Haynes Laurence Katznelson | 2008 | Journal of Hypertension2008，，2： | 2 |
| 9 | Fuctional cooperation between interleukin - 17 and tumor necrosis factor - α is nediated by CCAAT/enhance -binding protein family memers显示文摘 | Ruddy MJ Wong G Liu XK | 2004 | J Biol Chem2004，279，4： | 1 |
| 10 | Reninoma: case report and literature review显示文摘 | Wong L Hsu T H Perlroth M G etal | 2008 | J Hypertens2008，26，： | 1 |
| 11 | A vector space model for information retrieval显示文摘 | Sahon G Wong A Yang C S | 1975 | Communications of the ACM1975，，： | 1 |
| 12 | Nitrogen and phosphorus leaching from fertilizer applied on golf course: Lysimeter study 显示文摘 | Wong J W C Chan C W Y Cheung K G | 1998 | Water Air and Soil Pollution1998，107，： | 1 |
| 13 | Ultraviolet spontaneous and stimulated emissions from ZnO microcrystallite thin films at room temperature 显示文摘 | Zu P Tang Z K Wong G K L | 1997 | Solid State Commun1997，，103： | 1 |
| 14 | GATA-1 and Oct-1 are required for expression of the human alpha-hemoglobin-stabilizing protein gene 显示文摘 | Gallagher P G Liem R I Wong E | 2005 | J Biol Chem2005，280，39： | 1 |
| 15 | A Vector Space Model for Automatic Indexing显示文摘 | Salton G Wong A Yang C S | 1975 | Communications of the ACM1975，18，11： | 1 |
| 16 | A porous coordination copolymer with over 5 000 m《'2》/g BET surface area显示文摘 | KOH K WONG FOY A G MATZGER A J | 2009 | J Am Chem Soc2009，131，12： | 1 |
| 17 | Hybrid FRP-concrete-steel tubular col- umns:concept and behavior 显示文摘 | Teng J G Yu T Wong Y L | 2007 | Construction and Building Mate- rials2007，21，4： | 1 |
| 18 | The effect of different initial conditions on the exit flow from a fluidic precessing jet nozzle显示文摘 | Wong C Y Nathan G J O' Doherty T | 2003 | Experiments in Fluids2003，36，： | 1 |
| 19 | Electrical Conductivity and Dielectric Properties of PMMA/expanded Graphite Composites显示文摘 | ZHENG W G WONG S C | 2003 | Composites Science & Technology2003，，2： | 1 |
| 20 | A vector space model for automatic indexing 显示文摘 | G Salton A Wong C S Yang | 1975 | Communications of the ACM1975，18，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员