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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | An RTP/RTCP based approach for multimedia group and inter stream synchronization显示文摘 | FERNANDO B S JUAN C G C JAIME L M | 2008 | Multimedia Tools and Applications2008，40，2： | 1 |
| 3 | Breastfeeding and school achievement in Brazilian adolescents显示文摘 | Cesar G Fernando C Bernardo L | 2005 | Acta Paediatr2005，94，： | 1 |
| 4 | High Resolution Manometry Findings in Patients with Esophageal Epiphrenic Diverticula显示文摘 | Vicentine Fernando P P Herbella Fernando A M Silva Luciana C Patti Marco G | 2011 | The American Surgeon2011，，12： | 1 |
| 5 | Comparison of dis- ease severity and incidence at different growth stages of naturally infected canola plants under field conditions by pycnidiospores of Phoma lingam as a main source of inoc- ulum显示文摘 | Kaveh G Fernando D W G Gary C | 2011 | Canadian Journal of Plant Pathology2011，33，3： | 1 |
| 6 | On the use of cyanine dyes as low-band gap materials in bulkhetero junction photovoltaic deVices 显示文摘 | FERNANDO A C ANTONIN F THOMAS G | 2006 | Synthetic Metals2006，156，1415： | 1 |
| 7 | Feasibil- ity of spray cryotherapy and balloon dilation for non-ma- lignant strictures of the airway 显示文摘 | Fernando H C Dekeratry D Downie G | 2011 | Eur J Cardiothorac Surg2011，40，5： | 1 |
| 8 | Gas phase hydrogenation of m-dinitrohenzene over alumina supported Au and Au Ni/alloy显示文摘 | Fernando C L Santiago G Q Mark A K | 2009 | Catalysis Letters2009，127，12： | 1 |
| 9 | Stress-strain relationship in axial compression for concrete using recycledsaturated coarse aggregate显示文摘 | BELEN G F FERNANDO M A DIEGO C L | 2011 | Construction and Building materials2011，25，5： | 1 |
| 10 | A glogal view of reservoir fisheries 显示文摘 | Fernando C H Gurgel J J S Moyou N A G | 1998 | International Review of Hydrobiology1998，83，： | 1 |
| 11 | Effect of sorption kinetics on nickel toxicity in methanogenic granular sludge 显示文摘 | JAN B FERNANDO G F Alba B C | 2010 | Journal of Hazardous Materials2010，180，： | 1 |
| 12 | Differential effects of 1-Methylcyclopropene on citrus leaf and mature fruit abscission显示文摘 | POZO L YUAN R C KOSTENYUK I FERNANDO A ZHONG G Y BURNS J K | 2004 | Physiol Plant2004，129，4： | 1 |
| 13 | Biooxidation of a gold concentrate in a continuous stirred tank reactor: mathematical model and optimal configuration 显示文摘 | Ramon G Juan C G Fernando A | 2004 | Bio- chemical Engineering Journal2004，，19： | 1 |
| 14 | Value of the American College of Cardiology/American Heart Association angiographic classification of coronary lesion morphology in patients with in-stent restenosis显示文摘 | Fernando Alfonso Angel Cequier Juan Angel Vicens Martí Javier Zueco Armando Bethencourt Ramón Mantilla José R. López-Minguez Manuel Gómez-Recio César Morís María J. Perez-Vizcayno Cristina Fernández Carlos Macaya Ricardo Seabra-Gomes | 2006 | American Heart Journal2006，，3： | 1 |
| 15 | Identification and use of potential bacterial organic antifungal volatiles in biocontrol显示文摘 | Fernando W G D Ramarathnam R Krishnamoorthy A S Sav- chuk S C | 2005 | Soil Biology and Biochem- istry2005，37，5： | 1 |
| 16 | The Phzl/PhzR quorum-sensing system is required for pyrroini-trin and phenazine production,and exhibits cross-reg-ulation with RpoS in Pseudomonas chlororaphisPA23 显示文摘 | Selin C Fernando W G D de Kievit T | 2012 | Microbiology2012，158，89： | 1 |
| 17 | Physical activity and exercise recommendations for stroke survivors显示文摘 | Nell F Meg G Fernando C | 2004 | Stroke2004，35，5： | 1 |
| 18 | Characterization of recombinant Beta vulgaris 4,5-DOPA-extradiol-dioxygenase active in the biosynthesis of betalains 显示文摘 | Fernando G H Francisco G C | 2012 | Planta2012，236，1： | 1 |
| 19 | Effect of the application of silicon hydroxide on yield and quality of cher- ry tomato 显示文摘 | Fernando T S Antonio V G Francisco C F | 2012 | Journal of Plant Nutrition2012，35，4： | 1 |
| 20 | Reagentless biosensor for isocitrate using one step modified Pt - Ir microelectrode显示文摘 | PEREIRA A C FERNANDO L F NETO G DE O | 2001 | Talanta2001，53，： | 1 |
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