|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Does Helicobacter pylori eradication therapy for peptic ulcer prevent gastric cancer?显示文摘AIM:To investigate the effects of Helicobacter pylori (H pylori)eradication therapy for treatment of peptic ulcer on the incidence of gastric cancer. METHODS:A multicenter prospective cohort study was conducted between November 2000 and December 2007 in Yamagata Prefecture,Japan.The study included patients with H pylori-positive peptic ulcer who decided themselves whether to receive H pylori eradication(eradication group)or conventional antacid therapy(non-eradication group).Incidence of gastric cancer in the two groups was determined based on the results of annual endoscopy and questionnaire surveys,as well as Yamagata Prefectural Cancer Registry data,and was compared between the two groups and by results of H pylori therapy.RESULTS:A total of 4133 patients aged between 13 and 91 years(mean 52.9 years)were registered,and 56 cases of gastric cancer were identified over a mean follow-up of 5.6 years.The sex-and age-adjusted incidence ratio of gastric cancer in the eradication group, as compared with the non-eradication group,was 0.58 (95%CI:0.28-1.19)and ratios by follow-up period(<1 year,1-3 years,>3 years)were 1.16(0.27-5.00),0.50 (0.17-1.49),and 0.34(0.09-1.28),respectively.Longer follow-up tended to be associated with better prevention of gastric cancer,although not to a significant extent.No significant difference in incidence of gastric cancer was observed between patients with successful eradication therapy(32/2451 patients,1.31%)and those with treatment failure(11/639 patients,1.72%).Among patients with duodenal ulcer,which is known to be more prevalent in younger individuals,the incidence of gastric cancer was significantly less in those with successful eradication therapy(2/845 patients,0.24%)than in those with treatment failure(3/216 patients,1.39%). CONCLUSION:H pylori eradication therapy for peptic ulcer patients with a mean age of 52.9 years at registration did not significantly decrease the incidence of gastric cancer. | Katsuhiro Mabe Mikako Takahashi Haruhumi Oizumi Hideaki Tsukuma Akiko Shibata Kazutoshi Fukase Toru Matsuda Hiroaki Takeda Sumio Kawata | 2009 | World Journal of Gastroenterology2009，15，34： | 10 |
| 2 | Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial显示文摘 | Kazutoshi Fukase Mototsugu Kato Shogo Kikuchi Kazuhiko Inoue Naomi Uemura Shiro Okamoto Shuichi Terao Kenji Amagai Shunji Hayashi Masahiro Asaka | 2008 | The Lancet2008，，9636： | 7 |
| 3 | Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial显示文摘 | Kazutoshi Fukase Mototsugu Kato Shogo Kikuchi Kazuhiko Inoue Naomi Uemura Shiro Okamoto Shuichi Terao Kenji Amagai Shunji Hayashi Masahiro Asaka | 2008 | The Lancet . 2008 (9636)2008，，： | 4 |
| 4 | Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial显示文摘 | Kazutoshi Fukase Mototsugu Kato Shogo Kikuchi Kazuhiko Inoue Naomi Uemura Shiro Okamoto Shuichi Terao Kenji Amagai Shunji Hayashi Masahiro Asaka | 2008 | The Lancet2008，，9636： | 3 |
| 5 | Induction of thymidine phosphorylase activity and enhancement of capecitabine efficacy by taxol/taxotere in human cancer xenografts显示文摘 | Sawada N Ishikawa T Fukase Y | 1998 | Clin Cancer Res1998，4，： | 2 |
| 6 | Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial显示文摘 | Kazutoshi Fukase Mototsugu Kato Shogo Kikuchi Kazuhiko Inoue Naomi Uemura Shiro Okamoto Shuichi Terao Kenji Amagai Shunji Hayashi Masahiro Asaka | 2008 | 2008 (9636)2008，，9636： | 2 |
| 7 | The role of an anaerobic stage on biological phosphorus romovel显示文摘 | Fukase T Shibata M Miyaji Y | 1985 | Wat Sci Tech1985，，17： | 2 |
| 8 | Induction of thymidinephosphorylase activity and enhancement of capecitabine efficacy by Taxol Taxotere in human cancer xenografts显示文摘 | Sawda N Ishikawa T Fukase Y | 1998 | Clin Cancer Res1998，4，4： | 1 |
| 9 | A mild and general method for the synthesis of O-glycosides 显示文摘 | Fukase K Winarno H Kusumoto S | 1993 | Chem Express1993，8，： | 1 |
| 10 | 查看详情显示文摘 | Nishizaki T Sasaki T Fukase T Kobayashi N | | 0，，： | 1 |
| 11 | The effects of erythromycin on human peripheral neutrophil apoptosis显示文摘 | Inamura K Ohta N Fukase S | | 0，，03： | 1 |
| 12 | Hypermethylation of the RUNX3 gene promoter in testicular yolk sac tumor of infants显示文摘 | Kato N Tamura G Fukase M | 2003 | Am J Pathol2003，163，2： | 1 |
| 13 | Setting reac- tions and compressive strength of calcium phosphate cement 显示文摘 | FUKASE Y EANES E D TAKAGI S | 1990 | Journal of Dental Research1990，69，12： | 1 |
| 14 | Hemangiopericy- toma-induced osteomalacia: tumor transplantation in nude mice causes hypophosphatemia and tumor extracts inhibit re- nal 25-hydroxyvitamin D 1-hydroxylase activity 显示文摘 | Miyauchi A Fukase M Tsutsumi M | 1988 | J Clin Endocrinol Metab1988，67，： | 1 |
| 15 | Cell activation by monosaccharide lipid A analogues utilizing Toll-like receptor 4显示文摘 | Tamai R Asai Y Hashimoto M Fukase K | 2003 | Immunology2003，110，1： | 1 |
| 16 | Factors affecting biological removal of phosphorus显示文摘 | FUKASE T SHIBATA M MIYAJI Y | 1985 | Water Science and Technology1985，17，： | 1 |
| 17 | Effect of hyperlipaemic serum on interleukin-2 production,IL-2 receptor expression and T cell proliferation induced by IL-2 in cynomolgus monkeys显示文摘 | Terao K Fukase Y | 1991 | Med Sci Biol1991，44，： | 1 |
| 18 | Bile acids repress E-cad- herin through the induction of Snail and increase cancer invasive- hess in human hepatobibiary carcinoma 显示文摘 | Fukase K Ohtsuka H Onogawa T | 2008 | Cancer Sci2008，99，9： | 1 |
| 19 | Synthesis of a-glucosidase inhibitiory activity of N-substituted valiolsmine derivatives as potential oral antidiabetic agents显示文摘 | Horii S Fukase H | 1986 | The Journal of Medical Chemistry1986，29，： | 1 |
| 20 | Positive correlation between the efficacy of Capecitabine and doxifluridine and the ration ofthymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts显示文摘 | ISHIKAWA T SEKIGUCHI F FUKASE Y | 1998 | Cancer Res1998，58，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员