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| 1 | Neural invasion in pancreatic cancer: A mutual tropism between neurons and cancer cells显示文摘 | Güralp O. Ceyhan Ihsan Ekin Demir Burak Altintas Ulrich Rauch Gerald Thiel Michael W. Müller Nathalia A. Giese Helmut Friess Karl-Herbert Sch?fer | 2008 | Biochemical and Biophysical Research Communications2008,,3: | 2 |
| 2 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022,13,3: | 2 |
| 3 | Influence of QI on Mesophase St ructure显示文摘 | TAYLOR G H PENNOCK G M FITZ Gerald J D | 1993 | Carbon1993,31,2: | 1 |
| 4 | Beneficial effect of epilepsy surgery in a case of childhood non-paraneoplastic limbic encephalitis显示文摘 | Angelika M Gudrun G Gerald P | 2010 | Epilepsy Research2010,90,3: | 1 |
| 5 | DNA measurement and immunohistochemical characterization of epithelial and mesenchymal cells in canine mixed tumours:putative evidence for a common histogenesis显示文摘 | Gartner F Geraldes M Cassali G | 1999 | Vet J1999,158,: | 1 |
| 6 | Characterisation of ^67 Ga^3 + complexes of triaza macrocyclic ligands: biodistribution and clearance studies 显示文摘 | PRATA M I M SANTOS A C GERALDES C F G C | 1999 | Nucl Med Biol1999,26,6: | 1 |
| 7 | Spontaneous infectious discitis in adults 显示文摘 | Michael Hanan G Wesley White Gerald M | 1996 | The American Journal of Medicine1996,100,1: | 1 |
| 8 | Oral antidiabetic agents in pregnancy and lactation:a paradigm shift显示文摘 | DENICE S MSC M D GERALD G | 2007 | Ann Pharm2007,41,7: | 1 |
| 9 | Influence of QI on mesophase strucure显示文摘 | Taylor G H Pennock G M Gerald J D F | | 0,,02: | 1 |
| 10 | Bacteriophages in dairy products:Pros and cons显示文摘 | STEPHEN M G GERALD F | 2007 | Biotechnology Journal2007,2,: | 1 |
| 11 | Pediatric appendicitis:pathophysiology and appropriate use of diagnostic imaging显示文摘 | Gerald D G Brennan M D | 2006 | Can J Emerg Med2006,8,6: | 1 |
| 12 | The biochemistry of tea fermentation:oxidative degallation and epimerization of the tea flavanol gallates 显示文摘 | Philip C Gerald A M Harold N G | 1973 | Agr Food Chem1973,21,: | 1 |
| 13 | Estrogen regulation of endothelial and smooth muscle cell migration and proliferation:role of p38 and p42/44 mitogenactivated protein kinase显示文摘 | Geraldes P Sirois M G Bematchez P N Tanguay J F | 2002 | Arterioscler Thromb Vasc Boil2002,22,: | 1 |
| 14 | 显示文摘 | Gerald C Foster M Thomas G | 1993 | Chest1993,103,5: | 1 |
| 15 | Influence of the intertropical convergence zone on the East Asian monsoon显示文摘 | YANCHEVA G NOWACZYK N R MINGRAM J DULSKI P SCHETTLER G JORG F W NEGENDANK LIU J Q DANIEL M S LARRY C PETERSON GERALD H H | 2007 | Nature2007,445,: | 1 |
| 16 | Influence of QI on mesophase structure显示文摘 | Taylor G H Pennock G M Gerald J D | 1993 | Carbon1993,31,: | 1 |
| 17 | Profiling of complex microbial population by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA显示文摘 | Gerald M Ellen C D W Andre G U | 1993 | Applied and Environmental Microbiology1993,59,3: | 1 |
| 18 | Influence of QI on mesophase structure 显示文摘 | Taylor G H Pennock G M Fitz Gerald J D | 1993 | Carbon1993,31,2: | 1 |
| 19 | A power quality index based on equipment sensitivity,cost and network vulnerability显示文摘 | Lee G J Mihaela M A Gerald T H | 2004 | IEEE Trans on Power Delivery2004,19,3: | 1 |
| 20 | Intermediate - term experience of pipkin fracture - dislocations of the hip 显示文摘 | Marchetti Michael E Steinberg Gerald G Coumas James M | 1996 | Journal of Orthopaedic Trauma1996,10,7: | 1 |