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77篇 您的检索式:作者名="Gerald J D"
    题名 作者 年代 出处 被引量
1Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation.Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon 2012World Journal of Gastrointestinal Oncology2012,4,5:5
2Dislocation nucleation and multiplication in synthetic quartz:relevance to water weakening显示文摘McLaren A C Fitz Gerald J D Gerretsen J 1989Phys Chem Minerals1989,16,:1
3A review on the phytoeonstituents and related medicinal properties of plants in the As- teraceae family 显示文摘Aehika J I Arthur D E Gerald I 2014Journal of Applied Chemistry2014,7,8:1
4Influence of QI on Mesophase St ructure显示文摘TAYLOR G H PENNOCK G M FITZ Gerald J D 1993Carbon1993,31,2:1
5Technical basis and proposal for deriving sediment quality criteria for metals显示文摘Gerald T A Dominic M D T David J H 1996Environmental Toxicology and Chemistry1996,15,12:1
6Ferrite devices and materials 显示文摘Douglas J A Lionel E D Gerald F D 2002IEEE Transactions on Microwave Theory and Techniques2002,50,3:1
7Exsolution in hornblende and its consequence for 40Ar-39Ar age spectra and closure temperature显示文摘Harrison T M Fitz Gerald J D 1986Geochim Cosmochim Acta1986,50,:1
8Association of internal carotid artery injury with carotid canal fractures in patients with head trauma显示文摘Gerald Y Barboriak D Petrella J 2005Am J Radiol2005,184,5:1
9Maternal control of in- tegument cell elongation and zygotic control of endosperm growth are coordinated to determine seed size in Arabidop- sis 显示文摘Garcia D Gerald J N Berger F 2005Plant Cell2005,17,:1
10Experimental evaluation of a megavolt rod - pinch diode as a radiography source显示文摘Robert J Commisso Gerald Cooperstein David D Hinshelwood 2002IEEE Trans Plasma Sci2002,30,2:1
11Influence of QI on mesophase strucure显示文摘Taylor G H Pennock G M Gerald J D F 0,,02:1
12Atomic level resolution of dye regeneration in the dye-sensitized solar cell 显示文摘Robson Kiyoshi C D Hu Ke Meyer Gerald J 2013Journal of the American Chemical Society2013,135,:1
13Modification of the furanacryloyl-L-phenylalanyl-glycylglycine assay for determination of angiotensin I-converting enzyme inhibitory activity 显示文摘Murray B A Walsh D J Fitz Gerald R J 2004Journal of Biochemical and Biophysical Methods2004,59,2:1
14The Effect of Economic Similarity-Dissimilarity as Determinants of Attraction显示文摘BYRNE D E GERALD L C J WORCHEL P 1966Journal of Personality and Social Psychology1966,4,2:1
15Engineered interfaces for adherent diamond coatings on large thermal-expansion coefficient mismatched substrate 显示文摘SINGH R K GILBERT D R GERALD J F 1996Science1996,272,:1
16Structural features associated with degradable and persistent chemicals显示文摘Gerald J Niemi Gilman D Veith Ronald R Regal 1987Environ Toxicol Chem1987,6,7:1
17Characteristics of traffic crashes among young, middle-aged, and older drivers显示文摘Gerald MeGwin J Brown D B 1999Acci- dent Analysis & Prevention1999,31,3:1
18In vitro study of the insulin-mimetic behaviour of vanadium( Ⅳ, Ⅴ ) co-ordination compounds显示文摘Rehder D Costa P J Geraldes C F G C 2002J Biol Inorg Chem2002,7,:1
19Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death显示文摘Diwan Abhinav Matkovich Scot J Yuan Qunying Zhao Wen Yatani Atsuko Brown Joan Heller Molkentin Jeffery D Kranias Evangelia G Dorn Gerald W 2009Journal of Clinical Investigation2009,,1:1
20A multicenter comparison of intraaortic balloon pump utilization in isolated coronary artery bypass graft surgery显示文摘Roger J.F Baskett Gerald T O’Connor Gregory M Hirsch William A Ghali Kathy Sabadosa Jeremy R Morton Cathy S Ross Felix Hernandez William C Nugent Stephen J Lahey Donato A Sisto Lawrence J Dacey John D Klemperer Robert E Helm Andrew Maitland 2003The Annals of Thoracic Surgery2003,,6:1
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