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834篇 您的检索式:作者名="GU X M"
    题名 作者 年代 出处 被引量
1Structural basis of AMPK regulation by adenine nucleotides and glycogen显示文摘激活安培的蛋白质 kinase (AMPK ) 为糖尿病,肥胖,和癌症的治疗是一个中央细胞的精力传感器和精力动态平衡,和一个有希望的药目标的管理者。这里我们人的 α 的现在的低分辨率的水晶结构; 1 β 2 γ 1 holo-AMPK 建筑群跳了到它的 allosteric 调节的人安培和肝糖模仿 cyclodextrin,两个在 phosphorylated (4.05 Å) 并且 non-phosphorylated (4.60 Å) 状态。另外,我们解决了 2.95 Å人的 kinase 领域(KD ) 的结构跳了到邻近的 autoinhibitory 领域(帮助) 并且表现了广泛生物化学并且 mutational 研究。一起,这些研究由安培和肝糖说明 allosteric AMPK 调整的内在的机制,其绑定改变在交替的帮助(安培) 和糖类绑定模块(肝糖) 之间的 equilibria 相互作用。Xiaodan Li Lili Wang X Edward Zhou Jiyuan Ke Parker W de Waal Xin Gu M H Eileen Tan Dongye Wang Donghai Wu H Eric Xu Karsten Melcher 2015Cell Research2015,25,1:8
2Microstructure and properties of Ti-Si-N nanocomposite films显示文摘Hu X P Li G Y Gu M Y 2002J Vac Sci Tech A2002,20,6:2
3Transcatheter closure of membranous ventricular septal defects with a new nitinol prosthesis in a natural swine model显示文摘Gu X P Han Y M Titus J L 2000Cathete Cardiovasc Intervent2000,50,4:2
4Direct shear test of sandstone-concrete joints显示文摘GU X F SEIDEL J P HABERFIELD C M 2003International Journal of Geomechanics2003,3,1:1
5Worst case propagated uncertainty of multidisciplinary systems in robust design optimization显示文摘GU X Y RENAUD J E BATILL S M 2000Structural and Multidisciplinary Optimization2000,20,3:1
6Power dissipation analysis and optimization of deep submicron CMOS digital circuits 显示文摘Gu R X Elmasry M I 1996IEEE Journal on Solid State Circuits1996,31,5:1
7Laminar Burning Velocity and Markstein Lengths of Methane-Air Mixtures显示文摘Gu X J Haq M Z Lawes M 2000Combustion and Flame2000,121,12:1
8Pulse generators for pulsed electric field exposure of biological cells and tissues显示文摘Behrend M Kuthi A Gu X 2003Dielectrics and Electrical Insulation IEEE Transactions2003,10,:1
9Provenance and tectonic setting of the Proterozoic turbidites in Hunan, South China: Geochemical evi- dence显示文摘Gu X X Liu J M Zheng M H 2002Journal of Sedimentary Research2002,72,39:1
10Research progress of double-strained RNA interference( RNAi )in the application of different creatures 显示文摘Han P Wang X M Gu X F 2002Nature2002,24,2:1
11Provenance and tectonic setting of the Proterozoie turbidites in Hunan, south China: Geochemical evidence 显示文摘Gu X X Liu J M Zheng M H Tang 3 X Qi L 2002J Sediment Res2002,72,3:1
12A deadlock-free scheduling with sequence-dependent setup times显示文摘Zhang H Gu M Song X 2009International Journal of Advanced Manufacturing System2009,45,56:1
13Experimental investigation of rain-wind- induced vibration of cables in cable-stayed bridges and its mitigation 显示文摘Gu M Du X Q 2005Journal of Wind Engineering and Industrial Aerodynamics2005,93,:1
14Identification of Flutter Derivatives of Bridge Decks 显示文摘GU M ZHANG R X XIANG H F 2000Journal of Wind Engineering and Industrial Aerodynamics2000,84,2:1
15Formation of poly (vinylidene fluoride) (PVDF) membranes via thermally induced phase separation显示文摘Gu M Zhang J Wang X L 2006Desalination2006,192,:1
16Laminar Burning Velocity and Markstein Lengths of Methane-Air Mixtures 显示文摘Gu X J Haq M Z Lawes M 2000Combustion and Flame2000,121,:1
17Clinical and radiographic outcomes of the treatment of adolescent idiopathic scoliosis with segmental pedicle screws and combined local autograft and allograft bone for spinal fusion: a retrospective case series显示文摘Yang X Xu H IA M Gu S Fang X Wang J 2010BMC Musculoskelet Disord2010,11,:1
18显示文摘Gu H S Kuang A X Wang S M 1996Appl Phys Lett1996,68,9:1
19Normal vascular development in mice deficient in endothelial NO synthase:Possible role of neuronal NO synthase显示文摘Al-Shabrawey M El-Remessy A Gu X 2003Mol Vis2003,9,:1
20Determination of the adsorbate density from supercritical gas adsorption equilibrium data显示文摘LI M GU A Z LU X S WANG R S 2003Carbon2003,41,3:1
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