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| 1 | Concordance of non-invasive mechanical and serum tests for liver fibrosis evaluation in chronic hepatitis C显示文摘AIM To determine the sensitivity and specificity of liver stiffness measurement(LSM) and serum markers(SM) for liver fibrosis evaluation in chronic hepatitis C.METHODS Between 2012 and 2014,81 consecutive hepatitis C virus(HCV) patients had METAVIR score from liver biopsy compared with concurrent results from LSM [transient elastography(TE) [FibroS can~/ARFI technology(Virtual Touch~)] and SM [FIB-4/aspartate aminotransferase-toplatelet ratio index(APRI)].The diagnostic performance of these tests was assessed using receiver operating characteristic curves.The optimal cut-off levels of each test were chosen to define fibrosis stages F ≥ 2,F ≥ 3 and F = 4.The Kappa index set the concordance analysis.RESULTS Fifty point six percent were female and the median age was 51 years(30-78).Fifty-six patients(70%) weretreatment-na?ve.The optimal cut-off values for predicting F ≥ 2 stage fibrosis assessed by TE were 6.6 kP a,for acoustic radiation force impulse(ARFI) 1.22 m/s,for APRI 0.75 and for FIB-4 1.47.For F ≥ 3 TE was 8.9 kP a,ARFI was 1.48 m/s,APRI was 0.75,and FIB-4 was 2.For F = 4,TE was 12.2 kP a,ARFI was 1.77 m/s,APRI was 1.46,and FIB-4 was 3.91.The APRI could not distinguish between F2 and F3,P = 0.92.The negative predictive value for F = 4 for TE and ARFI was 100%.Kappa index values for F ≥ 3 METAVIR score for TE,ARFI and FIB-4 were 0.687,0.606 and 0.654,respectively.This demonstrates strong concordance between all three screening methods,and moderate to strong concordance between them and APRI(Kappa index = 0.507).CONCLUSION Given the costs and accessibility of LSM methods,and the similarity with the outcomes of SM,we suggest that FIB-4 as well as TE and ARFI may be useful indicators of the degree of liver fibrosis.This is of particular importance to developing countries. | Denise C Paranaguá-Vezozzo Adriana Andrade Daniel F C Mazo Vinicius Nunes Ana L Guedes Taisa G Ragazzo Renata Moutinho Lucas S Nacif Suzane K Ono Venancio A F Alves Flair J Carrilho | 2017 | World Journal of Hepatology2017，9，8： | 7 |
| 2 | Selecting suitable solid organ transplant donors: Reducing the risk of donor-transmitted infections显示文摘Selection of the appropriate donor is essential to a successful allograft recipient outcome for solid organ transplantation. Multiple infectious diseases have been transmitted from the donor to the recipient via transplantation. Donor-transmitted infections cause increased morbidity and mortality to the recipient. In recent years, a series of high-profile transmissions of infections have occurred in organ recipients prompt-ing increased attention on the process of improving the selection of an appropriate donor that balances the shortage of needed allografts with an approach that mitigates the risk of donor-transmitted infection to the recipient. Important advances focused on improving donor screening diagnostics, using previously excluded high-risk donors, and individualizing the selection of allografts to recipients based on their prior infection history are serving to increase the donor pool and improve outcomes after transplant. This article serves to review the relevant literature surrounding this topic and to provide a suggested approach to the selection of an appropriate solid organ transplant donor. | Christopher S Kovacs Jr Christine E Koval David van Duin Amanda Guedes de Morais Blanca E Gonzalez Robin K Avery Steven D Mawhorter Kyle D Brizendine Eric D Cober Cyndee Miranda Rabin K Shrestha Lucileia Teixeira Sherif B Mossad | 2014 | World Journal of Transplantation2014，4，2： | 7 |
| 3 | Glycine max (L.) Merr., Vigna radiata L. and Medicago sativa L. sprouts: A natural source of bioactive compounds显示文摘 | Luís R. Silva Maria J. Pereira Jessica Azevedo Rui F. Gon?alves Patrícia Valent?o Paula Guedes de Pinho Paula B. Andrade | 2013 | Food Research International2013，，1： | 2 |
| 4 | Inhibitory action of aqueous coffee ground extracts on the corrosion of carbon steel in HCl solution显示文摘 | Vanessa Vasconcelos Torres Roberto Salgado Amado Camila Faia de Sá Tatiana Lopez Fernandez Carlos Alberto da Silva Riehl Alexandre Guedes Torres Eliane D’Elia | 2011 | Corrosion Science2011，，7： | 1 |
| 5 | Steepness and asymmetry of the largest waves in stormy sea states 显示文摘 | Guedes S C Cherneva Z Antao E M | 2004 | Ocean Engineering2004，，31： | 1 |
| 6 | Allozyme variation among Brazilian and US populations of Rhyzopertha dominica resistant to insecticides显示文摘 | Guedes R N C Kambhampati S Dover B A | 1997 | Entomologia Experimentalis et Applicata1997，84，： | 1 |
| 7 | Analysis of Directional Wave Fileds Using X-band Navigation Radar显示文摘 | NIETO B J C GUEDES S C | 2000 | Journal of Coastal Engineering2000，40，1： | 1 |
| 8 | The association of carbonate alteration of banded iron formation with the Carajas high-grade hematite deposits 显示文摘 | Guedes S C Rosiere C A Barley M E | 2003 | Appl Earth Sci2003，12，： | 1 |
| 9 | Contact indentation of marine composites显示文摘 | SUTHERLAND L S GUEDES SOARES C | 2005 | Composite Structures2005，70，3： | 1 |
| 10 | H2 and Hinfin: designs for diving and course control of an autonomous underwater vehicle in presence of waves显示文摘 | Moreira L Guedes S C | 2008 | IEEE Journal of Oceanic Engineering2008，33，2： | 1 |
| 11 | Volatile biomarkers for wild mushrooms species discrimination显示文摘 | MALHEIRO R GUEDES DE PINHO P SOARES S | 2013 | Food Research International2013，54，1： | 1 |
| 12 | Thermal conffort criteria and building design: Field work in Portugal 显示文摘 | Manuel Correia Guedes Lul's Matias Carlos Pina Santos | 2009 | Renewable Energy2009，34，11： | 1 |
| 13 | Correlation between optical, chemical and micro-structural parameters of high-rank coals and graphite显示文摘 | MARQUES M SUAREZ-RUIZ I FLORES D GUEDES A RODRIGUES S | 2009 | Int J Coal Geol2009，77，34： | 1 |
| 14 | Experimental investigation of the nonlinear effects on the statistics of vertical motions and loads of a containership in irregular waves 显示文摘 | FONSECA N GUEDES S C | 2004 | J Ship Res2004，48，2： | 1 |
| 15 | The influence of starch gelatinization on the rheological,thermal,and morphological properties of poly(?-caprolactone)with corn starch blends显示文摘 | Rosa D S Guedes C G F Pedroso A G | 2004 | Materials Science and Engineering:C2004，24，5： | 1 |
| 16 | Modification of wheat straw lignin by solid state fermentation with white-rot fungi显示文摘 | Maria J. Dinis Rui M.F. Bezerra Fernando Nunes Albino A. Dias Cristina V. Guedes Luís M.M. Ferreira John W. Cone Guilhermina S.M. Marques Ana R.N. Barros Miguel A.M. Rodrigues | 2009 | Bioresource Technology2009，，20： | 1 |
| 17 | Steepness and Asymmetry of the Largest Waves in Storm Sea States显示文摘 | Guede S S C Cherneva Z Antao E M | 2004 | Ocean Engineering2004，31，89： | 1 |
| 18 | Spectral stochastic finite element analysis for laminated composite plates 显示文摘 | Chen N Z Guedes S C | 2008 | Computer Methods in Applied Mechanics and Engineering2008，197，50： | 1 |
| 19 | An experimental studyof ultimate torsional strength of a ship-type hull girder with a large deck opening显示文摘 | SUN Haihong GUEDES S C | 2003 | Marine Structures2003，，16： | 1 |
| 20 | The influence of starch gelatinization on the rheological,thermal,and morphological properties of poly (ε-caproolactone) with corn starch blends 显示文摘 | Roas D S Guedes C G F Pedroso A G | 2004 | Material Science and Engineering2004，24，： | 1 |
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