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| 1 | A model to predict survival in patients with end-stage liver disease显示文摘 | Patrick S. Kamath Russell H. Wiesner Michael Malinchoc Walter Kremers Terry M. Therneau Catherine L. Kosberg Gennaro D’Amico E.Rolland Dickson W.Ray Kim | 2001 | Hepatology2001,,2: | 10 |
| 2 | Natural history and prognostic indicators of survival in cirrhosis: A systematic review of 118 studies显示文摘 | Gennaro D’Amico Guadalupe Garcia-Tsao Luigi Pagliaro | 2005 | Journal of Hepatology2005,,1: | 8 |
| 3 | Role of nitric oxide in the impairment of circular muscle contractility of distended, uninflamed mid-colon in TNBS-induced acute distal colitis in rats显示文摘AIM: To evaluate the role of nitric oxide (NO) in the motor disorders of the dilated uninflamed mid-colon (DUMC)from trinitrobenzene sulfonic acid (TNBS)-induced acute distal colitis in rats.METHODS: Colitis was induced in male Sprague-Dawley rats by a single intracolonic administration of TNBS.Control rats received an enema of 0.9% saline. The rats were killed 48 h after TNBS or saline administration.Macroscopic and histologic lesions of the colon were evaluated. Myeloperoxidase (MPO) and nitric oxide synthase (NOS) activity were measured on the colonic tissue. In TNBS rats, we evaluated spontaneous and evoked contractile activity in circular muscle strips derived from DUMC in comparison to the same colonic segment of control rats, both in the presence and in the absence of a non-selective NOS isoforms inhibitor N-nitro-Larginine (L-NNA). Pharmacological characterization of electric field stimulation (EFS)-evoked contractile responses was also performed.RESULTS: In TNBS rats, the distal colon showed severe histological lesions and a high MPO activity, while the DUMC exhibited normal histology and MPO activity.Constitutive NOS activity was similar in TNBS and control rats, whereas inducible NOS activity was significantly increased only in the injured distal colon of TNBS rats.Isometrically recorded mechanical activity of circular muscle strips from DUMC of TNBS rats showed a marked reduction of the force and frequency of spontaneous contractions compared to controls, as well as of the contractile responses to a contracting stimulus. In the presence of L-NNA, the contractile activity and responses displayed a significantly greater enhancement compared to controls. The pharmacological characterization of EFS contractile responses showed that a cooperative-like interaction between cholinergic muscarinic and tachykinergic neurokinin 1 and 2 receptors mediated transmission in DUMC of TNBS rats vs a simple additive interaction in controls.CONCLUSION: The results of this study show that, during TNBS-induced acute distal colitis, circular muscle intrinsic contractile mechanisms and possible enteric neural excitatory activity are inhibited in the distended uninflamed mid-colon. Suppression of NO synthesis markedly improves spontaneous and evokes muscle contractions, in spite of any evident change in local NO activity. | Luciano Onori Annalisa Aggio Simona D'Alo' Paola Muzi Maria Grazia Cifone Gabriella Mellillo Rachele Ciccocioppo Gennaro Taddei Giuseppe Frieri Giovanni Latella | 2005 | World Journal of Gastroenterology2005,11,36: | 7 |
| 4 | Renal failure and cirrhosis: A systematic review of mortality and prognosis显示文摘 | Giuseppe Fede Gennaro D’Amico Vasiliki Arvaniti Emmanuel Tsochatzis Giacomo Germani Dimosthenis Georgiadis Alberto Morabito Andrew Kenneth Burroughs | 2011 | Journal of Hepatology2011,,4: | 4 |
| 5 | Headache, anxiety and depressive disorders: the HADAS study显示文摘 | Ettore Beghi Gennaro Bussone Domenico D’Amico Pietro Cortelli Sabina Cevoli Gian Camillo Manzoni Paola Torelli Maria Clara Tonini Giovanni Allais Roberto Simone Florindo D’Onofrio Sergio Genco Franca Moschiano Massimiliano Beghi Sara Salvi | 2010 | The Journal of Headache and Pain2010,,2: | 3 |
| 6 | Hepatic Vein Pressure Gradient Reduction and Prevention of Variceal Bleeding in Cirrhosis: A Systematic Review显示文摘 | Gennaro D’Amico Juan Carlos Garcia-Pagan Angelo Luca Jaime Bosch | 2006 | Gastroenterology2006,,5: | 2 |
| 7 | A model to predict survival in patients with end-stage liver disease显示文摘 | Patrick S. Kamath Russell H. Wiesner Michael Malinchoc Walter Kremers Terry M. Therneau Catherine L. Kosberg Gennaro D'Amico E.Rolland Dickson W.Ray Kim | 2001 | Hepatology2001,,2: | 2 |
| 8 | 外暴露组与呼吸道、皮肤过敏性疾病显示文摘变态反应是由多种遗传和环境因素相互作用导致的复杂疾病。然而,过去几十年间变态反应发生率的增加是由同期的环境变化所致。目前,研究者认为变态反应性疾病的发生、发展和恶化都可通过暴露组学加以解释,即从妊娠开始个体所接受的特异性和非特异性外部环境的暴露总量(外暴露组)及其对器官和细胞水平的影响(内暴露组)。在研究最深入的外暴露环境因素中,室内和室外空气变应原和空气污染物在变应原的炎性反应发病机制和变态反应性疾病的临床表现中发挥关键作用。气候变化、城市化和生物多样性的丧失会对主要的空气变应原和空气污染物的来源、排放和浓度造成影响,这将是现今和未来数十年变态反应患者的健康和生活质量所面临的最严峻的挑战之一。雷暴相关性哮喘是一个由多种环境因素作用引起的变态反应的生动例子,也可作为了解呼吸道过敏发病机制的体内模型。环境或生活方式引起的肠道和皮肤微生物组异常是变态反应性疾病的关键介质。更好地了解外暴露组对变态反应发展的影响对于敦促患者、卫生专业人员和政策制定者采取行动以减轻环境变化的影响,并适应环境变化具有重要意义。 | Lorenzo Cecchi Gennaro D Amato Isabella Annesi-Maesano 高楠楠(翻译) 王俊(翻译) 刘鹏 徐凯峰(审校) | 2018 | 中华临床免疫和变态反应杂志2018,12,5: | 2 |
| 9 | Early elevation of interleukin-1β and interleukin-6 levels after bare or drug-eluting stent implantation in patients with stable angina显示文摘 | Gennaro Sardella Paola Mariani Mariadomenica D’Alessandro Leonardo De Luca Marianna Pierro Massimo Mancone Alessandro Porretta Daniele Accapezzato Francesco Fedele Marino Paroli | 2005 | Thrombosis Research2005,,6: | 2 |
| 10 | Pharmacological Treatment of Portal Hypertension: An Evidence-Based Approach显示文摘 | Gennaro D’Amico Luigi Pagliaro Jaime Bosch | 1999 | Semin Liver Dis1999,,04: | 2 |
| 11 | Studies on the physicochemical properties of inulin and inulin oligomers显示文摘 | Gennaro S D Birch G G Parke S A | 2000 | Food Chemistry2000,68,: | 1 |
| 12 | Ion Exchange Selectivity of Phillipsite for Cs and Sr as a Function of Framework Composition显示文摘 | Adabbo M Caputo D de Gennaro B | 1999 | Micropor Mesopor Mater1999,30,: | 1 |
| 13 | Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm显示文摘 | Di Gennaro A W(a)gs(a)ter D M(a)yr(a)np(a)(a) MI | | 0,,: | 1 |
| 14 | Validating the Migraine-Specific Quality of Life Questionnaire v2.1 (MSQ) in Italian inpatients with chronic migraine with a history of medication overuse显示文摘 | Alberto Raggi Ambra Mara Giovannetti Silvia Schiavolin Matilde Leonardi Gennaro Bussone Licia Grazzi Susanna Usai Marcella Curone Paola Fiore Domenico D’Amico | 2014 | Quality of Life Research2014,,4: | 1 |
| 15 | Migraine, Celiac Disease, and Cerebral Calcifications: A New Case显示文摘 | Domenico D’Amico Andrea Rigamonti Luisa Spina Stefania Bianchi‐Marzoli Maurizio Vecchi Gennaro Bussone | 2005 | Headache: The Journal of Head and Face Pain2005,,9: | 1 |
| 16 | Proactive Security:Long-term protection against break-ins显示文摘 | CANETTI R GENNARO R HERZBERG D | 1997 | CryptoBytes1997,3,1: | 1 |
| 17 | Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators显示文摘 | Gennaro D’Amico Roberto De Franchis | 2003 | Hepatology2003,,3: | 1 |
| 18 | A 3‐Month Analysis of Disability, Quality of Life, and Disease Course in Patients With Migraine显示文摘 | Alberto Raggi Matilde Leonardi Gennaro Bussone Domenico D’Amico | 2012 | Headache: The Journal of Head and Face Pain2012,,2: | 1 |
| 19 | Proactive security:Long-term protection against break-ins显示文摘 | R Gennaro A Herzberg D Naor | 1997 | CryptoBytes1997,3,1: | 1 |
| 20 | Synergistic antitumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells显示文摘 | AVALLONE A D I Gennaro E BRUZZESE F | 2007 | Anticancer Drugs2007,18,7: | 1 |