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5篇 您的检索式:作者名="Geyang Wang"
    题名 作者 年代 出处 被引量
1A combined process of coating and hybridizing for the fabrication of carbon fiber reinforced aluminum matrix composites显示文摘WANG Jiwen HONG Tao LI Geyang 1997Composites Part A1997,28,11:1
2Regulation of gastric hormones by systemic rapamycin显示文摘Geyang Xu Yin Li Wenjiao An Jing Zhao Xinxin Xiang Li Ding Ziru Li Youfei Guan Xian Wang Chaoshu Tang Yi Zhu Nanping Wang Xiaoying Li Michael Mulholland Weizhen Zhang 2010Peptides2010,,12:1
3Sub-40-fs high-power Yb:CALYO laser pumped by single-mode fiber laser显示文摘We report on the study of single-mode fiber-laser-pumped mode-locked Yb:CALYO lasers via using a passive saturable absorber and Kerr-lens mode-locking technique,respectively.Up to 3.1-W average power with 103-fs pulse duration is obtained from the passive mode-locking,and down to 36-fs pulse duration with more than 2-W average power is achieved by the pure Kerr-lens mode-locking,which is to the best of our knowledge,the highest average power from a reported sub-40-fs Yb-based solid-state oscillator.Wenlong Tian Geyang Wang Dacheng Zhang Jiangfeng Zhu Zhaohua Wang Xiaodong Xu Jun Xu Zhiyi Wei 2019High Power Laser Science and Engineering2019,7,4:1
4Suppressing meta-holographic artifacts by laser coherence tuning显示文摘A metasurface hologram combines fine spatial resolution and large viewing angles with a planar form factor and compact size.However,it suffers coherent artifacts originating from electromagnetic cross-talk between closely packed meta-atoms and fabrication defects of nanoscale features.Here,we introduce an efficient method to suppress all artifacts by fine-tuning the spatial coherence of illumination.Our method is implemented with a degenerate cavity laser,which allows a precise and continuous tuning of the spatial coherence over a wide range,with little variation in the emission spectrum and total power.We find the optimal degree of spatial coherence to suppress the coherent artifacts of a meta-hologram while maintaining the image sharpness.This work paves the way to compact and dynamical holographic displays free of coherent defects.Yaniv Eliezer Geyang Qu Wenhong Yang Yujie Wang Hasan Yılmaz Shumin Xiao Qinghai Song Hui Cao 2021Light(Science & Applications)2021,10,7:0
5Reactivation of PPARαalleviates myocardial lipid accumulation and cardiac dysfunction by improving fatty acidβ-oxidation in Dsg2-deficient arrhythmogenic cardiomyopathy显示文摘Arrhythmogenic cardiomyopathy(ACM),a fatal heart disease characterized by fibroadipocytic replacement of cardiac myocytes,accounts for 20%of sudden cardiac death and lacks effective treatment.It is often caused by mutations in desmosome proteins,with Desmoglein-2(DSG2)mutations as a common etiology.However,the mechanism underlying the accumulation of fibrofatty in ACM remains unknown,which impedes the development of curative treatment.Here we investigated the fat accumulation and the underlying mechanism in a mouse model of ACM induced by cardiac-specific knockout of Dsg2(CS-Dsg2^(-/-)).Heart failure and cardiac lipid accumulation were observed in CSDsg2^(-/-)mice.We demonstrated that these phenotypes were caused by decline of fatty acid(FA)β-oxidation resulted from impaired mammalian target of rapamycin(m TOR)signaling.Rapamycin worsened while overexpression of m TOR and 4EBP1 rescued the FAβ-oxidation pathway in CS-Dsg2^(-/-)mice.Reactivation of PPARa by fenofibrate or AAV9-Ppara significantly alleviated the lipid accumulation and restored cardiac function.Our results suggest that impaired m TOR-4EBP1-PPARa-dependent FAβ-oxidation contributes to myocardial lipid accumulation in ACM and PPARa may be a potential target for curative treatment of ACM.Yubi Lin Ruonan Liu Yanling Huang Zhe Yang Jianzhong Xian Jingmin Huang Zirui Qiu Xiufang Lin Mengzhen Zhang Hui Chen Huadong Wang Jiana Huang Geyang Xu 2023Acta Pharmaceutica Sinica B2023,13,1:0
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