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| 1 | The Antagonistic Action of Abscisic Acid and Cytokinin Signaling Mediates Drought Stress Response in Arabidopsis显示文摘 | Xiaozhen Huang Lingyan Hou Jingjing Meng Huiwen You Zhen Li Zhizhong Gong Shuhua Yang Yiting Shi | 2018 | Molecular Plant2018，11，7： | 15 |
| 2 | Mesoporous silica nanorods intrinsically doped with photosensitizers as a multifunctional drug carrier for combination therapy of cancer显示文摘Mesoporous 硅石 nanoparticles (MSN ) 由于他们的大表面区域,悦耳的尺寸,灵巧的修正和可观的 biocompatibility 作为药交货搬运人在最近的年里吸引了巨大的注意。在这个工作,我们制作内在地与使分子具有感光性被做的 MSN 的一种有趣的类型,氯 e6 (Ce6 ) 。由增加在硅石矩阵内做的 Ce6 的数量, MSN 的形态学从范围改变到像杆的形状,这被发现。获得的做 Ce6 的 mesoporous 硅石 nanorods (CMSNR ) 不仅能为光力学的治疗,而且罐头生产汗衫氧也与由利用他们的 mesoporous 结构装载能力的高药用作一个药交货平台。比作球形的 nanoparticles,有更大的方面比率的 CMSNR 由癌症房间显示出许多更快的举起,这被发现。与作为模型药采用的 doxorubicin (纪录影片) ,联合光力学并且化疗被执行,在 vitro 并且在 vivo 完成 synergistic 反肿瘤效果。我们的学习介绍一个基于 MSN 的药交货平台的一个新图案,它内在地荧光灯、有能力用作一个光力学的代理人,为未来答应癌症的指导成像的联合治疗。 | Guangbao Yang Hua Gong Xiaoxin Qian Pengli Tan Zhiwei Li Teng Liu Jingjing Liu Youyong Li Zhuang Liu | 2015 | Nano Research2015，8，3： | 11 |
| 3 | Erratum to: Sn^(4+) precursor enables 12.4% efficient kesterite solar cell from DMSO solution with open circuit voltage deficit below 0.30 V (vol 64, issue 1, page 52, 2021)显示文摘In the version of the article originally published in volume 64,issue 1,2021 of Sci China Mater(2021,64(1):52–60,http://gffzzd3cc09b8251d45dfsucbf90v6vwb66fb0.ffgz.tsg.suse.edu.cn/10.1007/s40843-020-1408-x),the chemical formula of Sn(DMSO)_(4)Cl_(4)(page 54,8^(th) line in the left column;page 56,4^(th) and 6^(th) lines from the bottom of left column and in Equations(6 and 7)in the right column)was miswritten.The correct formula should be as below:SN(DMSO)_(2)CL_(4). | Yuancai Gong Yifan Zhang Erin Jedlicka Rajiv Giridharagopal James A.Clark Weibo Yan Chuanyou Niu Ruichan Qiu Jingjing Jiang Shaotang Yu Sanping Wu Hugh W.Hillhouse David S.Ginger Wei Huang Hao Xin | 2021 | Science China Materials2021，64，5： | 7 |
| 4 | Exogenous Melatonin Improves Physiological Characteristics and Promotes Growth of Strawberry Seedlings Under Cadmium Stress显示文摘Melatonin,as a plant growth regulator,is involved in plant stress resistance.We studied the effects of different concentrations(0,10,50,100,150,and 200μmol·L−1)of melatonin on the growth and physiological characteristics of strawberry under cadmium(Cd)stress.The results represented that the growth of strawberry seedlings was inhibited under Cd stress,and the seedling biomass,chlorophyll content and the activities of antioxidant enzymes such as superoxide dismutase(SOD),peroxidase(POD),catalase(CAT),and ascorbate peroxidase(APX)decreased.These toxic effects were,however,effectively remediated by exogenous melatonin pretreatment.Melatonin treatment slowed the inhibitory effect of seedling growth and significantly increased seedling biomass,chlorophyll content,antioxidant enzyme activities,and soluble protein levels in leaves and roots compared with the control.Melatonin treatment also reduced the malondialdehyde(MDA)content and the oxidative stress reactions,increased the anthocyanin content,and slowed the senescence rate,thereby reducing the toxic effects of Cd on strawberries.This indicates that foliar application of melatonin can effectively remediate the adverse effects of Cd on strawberry seedlings;the greatest effect was obtained with melatonin concentration of 100μmol·L−1. | Shuqing Wu Yao Wang Junkang Zhang Xiaojun Gong Zhen Zhang Jingjing Sun Xuesen Chen Yanling Wang | 2021 | Horticultural Plant Journal2021，7，1： | 6 |
| 5 | Microstructure optimization of core@shell structured MSe_(2)/FeSe_(2)@MoSe_(2)(M=Co,Ni)flower-like multicomponent nanocomposites towards high-efficiency microwave absorption显示文摘In this work,we put forward a scheme to exquisitely design and selectively synthesize the core@shell structured MSe_(2)/FeSe_(2)@MoSe_(2)(M=Co,Ni)flower-like multicomponent nanocomposites(MCNCs)through a simple two-step hydrothermal reaction on the surfaces of MFe_(2)O_4 nanospheres with the certain amounts of Mo and Se sources.With increasing the amounts of Mo and Se sources,the obtained core@shell structured MSe_(2)/FeSe_(2)@MoSe_(2)(M=Co,Ni)MCNCs with the enhanced content of MoSe_(2)and improved flower-like geometry morphology could be produced on a large scale.The obtained results revealed that the as-prepared samples displayed improved comprehensive microwave absorption properties(CMAPs)with the increased amounts of Mo and Se sources.The as-prepared CoSe_(2)/FeSe_(2)@MoSe_(2)and NiSe_(2)/FeSe_(2)@MoSe_(2)MCNCs with the well-defined flower-like morphology could simultaneously present the outstanding CMAPs in terms of strong absorption capability,wide absorption bandwidth,and thin matching thicknesses,which mainly originated from the conduction loss and flower-like geometry morphology.Therefore,the findings not only develop the very desirable candidates for high-performance microwave absorption materials but also pave a new way for optimizing the CMAPs through tailoring morphology engineering. | Jingjing Zhang Xiaosi Qi Xiu Gong Qiong Peng Yanli Chen Ren Xie Wei Zhong | 2022 | Journal of Materials Science & Technology2022，，33： | 5 |
| 6 | Intelligent multi-user detection using an artificial immune system显示文摘Artificial immune systems (AIS) are a kind of new computational intelligence methods which draw inspiration from the human immune system. In this study, we introduce an AIS-based optimization algorithm, called clonal selection algorithm, to solve the multi-user detection problem in code-division multipleaccess communications system based on the maximum-likelihood decision rule. Through proportional cloning, hypermutation, clonal selection and clonal death, the new method performs a greedy search which reproduces individuals and selects their improved maturated progenies after the affinity maturation process. Theoretical analysis indicates that the clonal selection algorithm is suitable for solving the multi-user detection problem. Computer simulations show that the proposed approach outperforms some other approaches including two genetic algorithm-based detectors and the matched filters detector, and has the ability to find the most likely combinations. | GONG MaoGuo, JIAO LiCheng, MA WenPing & MA JingJing Key Laboratory of Intelligent Perception and Image Understanding of Ministry of Education of China Institute of Intelligent Information Processing, Xidian University, Xi’an 710071, China | 2009 | Science in China(Series F)2009，52，12： | 5 |
| 7 | Coriander Genomics Database:a genomic,transcriptomic,and metabolic database for coriander显示文摘Coriander(Coriandrum sativum L.),also known as cilantro,is a globally important vegetable and spice crop.Its genome and that of carrot are models for studying the evolution of the Apiaceae family.Here,we developed the Coriander Genomics Database(CGDB,http://gffzzc8ce0bd092c048a1hucbf90v6vwb66fb0.ffgz.tsg.suse.edu.cn/)to collect,store,and integrate the genomic,transcriptomic,metabolic,functional annotation,and repeat sequence data of coriander and carrot to serve as a central online platform for Apiaceae and other related plants.Using these data sets in the CGDB,we intriguingly found that seven transcription factor(TF)families showed significantly greater numbers of members in the coriander genome than in the carrot genome.The highest ratio of the numbers of MADS TFs between coriander and carrot reached 3.15,followed by those for tubby protein(TUB)and heat shock factors.As a demonstration of CGDB applications,we identified 17 TUB family genes and conducted systematic comparative and evolutionary analyses.RNA-seq data deposited in the CGDB also suggest dose compensation effects of gene expression in coriander.CGDB allows bulk downloading,significance searches,genome browser analyses,and BLAST searches for comparisons between coriander and other plants regarding genomics,gene families,gene collinearity,gene expression,and the metabolome.A detailed user manual and contact information are also available to provide support to the scientific research community and address scientific questions.CGDB will be continuously updated,and new data will be integrated for comparative and functional genomic analysis in Apiaceae and other related plants. | Xiaoming Song Fulei Nie Wei Chen Xiao Ma Ke Gong Qihang Yang Jinpeng Wang Nan Li Pengchuan Sun Qiaoying Pei Tong Yu Jingjing Hu Xinyu Li Tong Wu Shuyan Feng Xiu-Qing Li Xiyin Wang | 2020 | Horticulture Research2020，7，1： | 4 |
| 8 | High-resolution mapping of brain vasculature and its impairment in the hippocampus of Alzheimer’s disease mice显示文摘Accumulating evidence indicates the critical importance of cerebrovascular dysfunction in the pathogenesis of Alzheimer’s disease(AD).However,systematic comparative studies on the precise brain vasculature of wild-type and AD model mice are still rare.Using an image-optimization method for analysing Micro-Optical Sectioning Tomography(MOST)data,we generated cross-scale whole-brain 3 D atlases that cover the entire vascular system from large vessels down to smallest capillaries at submicron resolution,for both wild-type mice and a transgenic(APP/PS1)mouse model of AD.In addition to distinct vascular patterns in different brain regions,we found that the main vessels of the molecular layer of the hippocampal dentate gyrus(DG-ml)undergo abrupt changes in both diameter and branch angle,spreading a unique comb-like pattern of capillaries.By using a quantitative analysis workflow,we identified in the hippocampus of AD mice an overall reduction of the mean vascular diameter,volume fraction and branch angle,with most significant impairment in the DG-ml.In addition,virtual endoscopy revealed irregular morphological features in the vessel lumen of the AD mice,potentially contributing to the impairment of blood flow.Our results demonstrate the capability of high-resolution cross-scale evaluation of brain vasculature and underscore the importance of studying hippocampal microcirculation for understanding AD pathogenesis. | Xiaochuan Zhang Xianzhen Yin Jingjing Zhang Anan Li Hui Gong Qingming Luo Haiyan Zhang Zhaobing Gao Hualiang Jiang | 2019 | National Science Review2019，6，6： | 4 |
| 9 | Heat shock protein inhibitor, quercetin, as a novel adjuvant agent to improve radiofrequency ablation-induced tumor destruction and its molecular mechanism显示文摘Background: We investigated the effect of a small molecular inhibitor of heat shock protein(HSP), quercetin, on tumor radiofrequency(RF) ablation, and explored the underlying molecular mechanisms.Methods: In in vivo study, rats with R3230 breast adenocarcinoma were sacrificed 24 h post-treatment and gross coagulation areas were compared, and next, randomized into four treatment arms(control, quercetin alone, RF alone, and combination) for Kaplan-Meier analysis of defined endpoint survival. Then the distribution and expression levels of heat shock protein 70(HSP70), cleaved caspase-3 and heat shock factor 1(HSF1) were analyzed after different treatments. In in vitro study, we used quercetin to promote SKHEP-1(hepatic) and MCF-7(breast) cancer cell apoptosis in heat shock cell model, and si RNA was used to block c-Jun and to explore the role of activating protein-1(AP-1) signaling pathways.Results: We found the effects of quercetin plus RFA resulted in increase on the tumor destruction/endpoint survival(26.5±3.4 d) in vivo, compared with RF alone(17.6±2.5 d) and quercetin alone(15.7±3.1 d). Most importantly, quercetin-induced cancer cell death required the presence of HSF1 in animal model. Furthermore, quercetin directly down-regulated expression of HSF1 in vitro, which our findings have revealed, required the activation of AP-1 signaling pathways by loss-of-function analysis using si RNA mediated targeting of c-Jun.Conclusions: These results indicated a protective role of quercetin in tumor ablation and highlighted a novel mechanism involving HSP70 with HSF1 pathway in thermal ablation of solid tumors. | Wei Yang Ming Cui Jungchieh Lee Wei Gong Song Wang Jingjing Fu Gongxiong Wu Kun Yan | 2016 | Chinese Journal of Cancer Research2016，28，1： | 4 |
| 10 | Treated dentin matrix induces odontogenic differentiation of dental pulp stem cells via regulation of Wnt/β-catenin signaling显示文摘Treated dentin matrix(TDM)is an ideal scaffold material containing multiple extracellular matrix factors.The canonical Wnt signaling pathway is necessary for tooth regeneration.Thus,this study investigated whether the TDM can promote the odontogenic differentiation of human dental pulp stem cells(hDPSCs)and determined the potential role of Wnt/β-catenin signaling in this process.Different concentrations of TDM promoted the dental differentiation of the hDPSCs and meanwhile,the expression of GSK3βwas decreased.Of note,the expression of the Wnt/β-catenin pathway-related genes changed significantly in the context of TDM induction,as per RNA sequencing(RNA seq)data.In addition,the experiment showed that new dentin was visible in rat mandible cultured with TDM,and the thickness was significantly thicker than that of the control group.In addition,immunohistochemical staining showed lower GSK3βexpression in new dentin.Consistently,the GSK3βknockdown hDPSCs performed enhanced odotogenesis compared with the control groups.However,GSK3βoverexpressing could decrease odotogenesis of TDM-induced hDPSCs.These results were confirmed in immunodeficient mice and Wistar rats.These suggest that TDM promotes odontogenic differentiation of hDPSCs by directly targeting GSK3βand activating the canonical Wnt/β-catenin signaling pathway and provide a theoretical basis for tooth regeneration engineering. | Sirui Liu Jingjing Sun Shuai Yuan Yanyu Yang Yuping Gong Ying Wang Runying Guo Xue Zhang Yiming Liu Hongyan Mi Meiyue Wang Mengzhe Liu Rui Li | 2022 | Bioactive Materials2022，7，1： | 2 |
| 11 | Comparison of lateral episiotomy,traditional midwifery without episiotomy,and hands-off techniques delivery on pelvic floor function显示文摘Background Prolonged vaginal delivery times and episiotomy are associated with damage to the muscles of the pelvic floor,and with complications that include postpartum sexual dysfunction and urinary stress incontinence.This study was to compare the pelvic floor function among postpartum women who underwent three midwifery practices during labor:lateral episiotomy,traditional midwifery without episiotomy,and hands-off techniques delivery.Methods We included 320 primipara who were full-term pregnancy and underwent vaginal delivery in Department of Obstetrics,Peking University People’s Hospital,China.117 women had episiotomy during labor and were classified into the lateral episiotomy group;103 had traditional midwifery without episiotomy and were classified into the traditional midwifery practice group;and 100 experienced hands-off techniques during labor and were classified into the hands-off techniques delivery group.The duration of the second stage of labor,and postpartum pelvic floor muscle strength were compared between the three study groups.Results There were no significant differences between the three groups for the duration of the second stage of labor and postpartum pelvic floor muscle strength(P>0.05).However,the incidence of postpartum urinary stress incontinence and sexual dysfunction in the hands-off techniques delivery group was significantly lower than in the lateral episiotomy groups and the traditional midwifery practice group(P<0.01).Conclusions Hands-off techniques delivery could reduce damage to the pelvic floor and improve the quality of life for women after delivery. | Jingjing Gong Lili Xing Xiaodan Li Xiaona Wang Huijuan Chen | 2021 | Gynecology and Obstetrics Clinical Medicine2021，1，1： | 2 |
| 12 | Angiotensin I converting enzyme(ACE)inhibitory activity and antihypertensive effects of rice peptides显示文摘In this paper,the antihypertension effect of rice peptide(RP)was studied.With spontaneously hypertensive rats(SHR)and Wistar Kyoto(WKY)as the research objects,RP disposable gastric and long-term gastric irrigation experiments were carried out and systolic blood pressure(SBP)was measured.At the end of the long-term gastric irrigation experiment,the content of nitric oxide(NO),angiotensin-converting enzyme(ACE),angiotensin II(Ang II)and renin in the plasma and the activity of ACE were determined.The results showed that RP could reduce systolic pressure of SHR and had time-dose dependence while high-dose RP signifi cantly reduced systolic pressure by 24.6 and 17.2 mm Hg,respectively after a single and long-term gastric irrigation test.RP also could inhibit the activity of ACE and increase the release of NO.These results suggested that the decompression mechanism of RP is likely to be related to the regulation of the renin-angiotensin system(RAS)and NO. | Jingjing Dong Shen Wang Xiaoyao Yin Min Fang Zhiyong Gong Yongning Wu | 2022 | Food Science and Human Wellness2022，11，6： | 2 |
| 13 | Determination of inhibitory activity of Salvia miltiorrhiza extracts on xanthine oxidase with a paper-based analytical device显示文摘A novel paper-based analytical device(PAD)was prepared and applied to determine the xanthine oxidase(XOD)inhibitory activity of Salvia miltiorrhiza extracts(SME).First,polycaprolactone was 3D printed on filter paper and heated to form hydrophobic barriers.Then the modified paper was cut according to the specific design.Necessary reagents including XOD for the colorimetric assay were immobilized on two separate pieces of paper.By simply adding phosphate buffer,the reaction was performed on the double-layer PAD.Quantitative results were obtained by analyzing the color intensity with the specialized device system(consisting of a smartphone,a detection box and sandwich plates).The 3Dprinted detection box was small,with a size of 9.0 cm×7.0 cm×11.5 cm.Color component G performed well in terms of linearity and detection limits and thus was identified as the index.The reaction conditions were optimized using a definitive screening design.Moreover,a 10%glycerol solution was found to be a suitable stabilizer.When the stabilizer was added,the activity of XOD could be maintained for at least 15 days under 4℃ or-20℃ storage conditions.The inhibitory activity of SME was investigated and compared to that of allopurinol.The results obtained with the PAD showed agreement with those obtained with the microplate method.In conclusion,the proposed PAD method is simple,accurate and has a potential for point-of-care testing.It also holds promise for use in rapid quality testing of medicinal herbs,intermediate products,and preparations of traditional Chinese medicines. | Xingchu Gong Jingyuan Shao Shangxin Guo Jingjing Pan Xiaohui Fan | 2021 | Journal of Pharmaceutical Analysis2021，11，5： | 1 |
| 14 | Dying tumor cells stimulate proliferation of living tumor cells via caspase-dependent protein kinase Cδ activation in pancreatic ductal adenocarcinoma显示文摘 | Jin Cheng Ling Tian Jingjing Ma Yanping Gong Zhengxiang Zhang Zhiwei Chen Bing Xu Hui Xiong Chuanyuan Li Qian Huang | 2014 | Molecular Oncology2014，，： | 1 |
| 15 | A benzenediamine derivate FC-99 attenuates lupus nephritis in MRLIIpr mice via inhibiting myeloid dendritic cell-secreted BAFF显示文摘Myeloid 树枝状的房间(DC ) 能生产调制 B 房间的幸存和区别并且在全身的豺狼座 erythematosus (SLE ) 的致病起一个枢轴的作用的 B-cell-activating 因素(BAFF ) 。像使用费的受体 4 (TLR4 ) 发信号在 BAFF 的进程有重要函数生产。我们的以前的学习证明 benzenediamine derivate FC-99 拥有反发炎活动并且直接与 interleukin-1 交往联系受体的 kinase 4 (IRAK4 ) ,它是在 TLR4 发信号的一个枢轴的分子。在这研究,我们证明 FC-99 在 MRL/lpr 老鼠稀释了豺狼座肾炎。FC-99 也减少了在 sera 的全部的免疫球蛋白 G (IgG ) 的层次,全部的 IgG2a 和 IgM,以及在 MRL/lpr 老鼠的怒气的 B 房间的激活。而且, FC-99 在怒气禁止了 myeloid DC 的反常激活并且在 MRL/lpr 老鼠的 sera,怒气,和肾减少了 BAFF 的层次。在有在 vitro 的 lipopolysaccharide 的 TLR4 刺激之上,而且, FC-99 在鼠科的骨头禁止了 IRAK4 phosphorylation,以及激活和 BAFF 生产导出髓的 DC。这些数据显示 FC-99 经由禁止藏匿 DC 的 BAFF 在 MRL/lpr 鼠标稀释豺狼座肾炎,建议那 FC-99 可以是 SLE 的处理的一个潜在的治疗学的候选人。 | Jianjian Ji Jingjing Xu Fanlin Li Xiaojing Li Wei Gong Yuxian Song Huan Dou Yayi Hou | 2016 | Acta Biochimica et Biophysica Sinica2016，48，5： | 1 |
| 16 | Change detection in syn- thetic aperture radar images based on image fusion and fuzzy cluste- ring显示文摘 | Gong Maoguo Zhou Zhiqiang Ma Jingjing | 2012 | IEEE Trans on Image Processing2012，21，4： | 1 |
| 17 | A retrospective analysis of carbapenem-resistant Acinetobacter baumannii-mediated nosocomial pneumonia and the in vitro therapeutic benefit of cefoperazone/sulbactam显示文摘 | Jingjing Xia Duchao Zhang Yaping Xu Meiliang Gong Yu Zhou Xiangqun Fang | 2014 | International Journal of Infectious Diseases2014，23，5： | 1 |
| 18 | Valine-- derived phos- phinothiourea as organocatalyst in enantioselective Morita- Baylis--Hillman reactions of acrylates with aromatic aldehydes 显示文摘 | Gong Jingjing Yuan Kui Wu Xinyan | 2009 | Tetrahedron: Asymmetry2009，20，： | 1 |
| 19 | Mapping QTLs on BTA6 affecting milk production traits in a Chinese Holstein population显示文摘A Chinese Holstein population with daughter design was analyzed using 14 microsatellites covering a map distance of 55.7 cM on chromosome 6 to fine map QTL for five milk production traits. 26 paternal half-sib families with 2356 daughters were involved. Two different approaches, linear regression approach and variance component ap-proach, were employed, with a one-QTL model and two-QTL model fitted. With a one-QTL model, the linear regression approach revealed a QTL near BMS470 with effects on milk yield, fat yield, protein yield, and fat percentage, and another QTL near BMS2460 for protein percentage. The variance component approach confirmed the results of linear regres-sion approach for the three yield traits, with the exception that the QTL for fat yield was mapped to a different position near BMS1242. The 95% confidence intervals resulted from linear regression, obtained by bootstrapping, were generally large, ranging from 31 to 53 cM, whereas the variance com-ponent approach revealed very small confidence intervals, calculated by LOD drop-off method, for the three yield traits, only 4―5 cM. With a two-QTL model, both approaches pro-vided strong evidence for the existence of two QTLs for the three yield traits. Along with the QTLs identified in one-QTL model analyses, the linear regression approach revealed a second QTL near BP7 with effects on all the three yield traits, whereas the variance component approach located the sec-ond QTL near ILSS035, BMS470, and BP7 for the three traits, respectively. | CHEN Huiyong ZHANG Qin WANG Chunkao SHU Juan MEI Gui YIN Cengceng HU Fang XU Jingjing GONG Weijia LI Hejun QIU Xiaotian | 2005 | Chinese Science Bulletin2005，50，16： | 1 |
| 20 | Characterizing and Understanding Development of Social Computing Through DBLP: A Data-Driven Analysis显示文摘During the past decades,the term“social computing”has become a promising interdisciplinary area in the intersection of computer science and social science.In this work,we conduct a data-driven study to understand the development of social computing using the data collected from Digital Bibliography and Library Project(DBLP),a representative computer science bibliography website.We have observed a series of trends in the development of social computing,including the evolution of the number of publications,popular keywords,top venues,international collaborations,and research topics.Our findings will be helpful for researchers and practitioners working in relevant fields. | Jiaqi Wu Bodian Ye Qingyuan Gong Atte Oksanen Cong Li Jingjing Qu Felicia F.Tian Xiang Li Yang Chen | 2022 | Journal of Social Computing2022，3，4： | 1 |
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