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| 1 | Video capsule endoscopy:Perspectives of a revolutionary technique显示文摘Video capsule endoscopy(VCE)was launched in 2000and has revolutionized direct endoscopic imaging of the gut.VCE is now a first-line procedure for exploring the small bowel in cases of obscure digestive bleeding and is also indicated in some patients with Crohn’s disease,celiac disease,and polyposis syndrome.A video capsule has also been designed for visualizing the esophagus in order to detect Barrett’s esophagus or esophageal varices.Different capsules are now available and differ with regard to dimensions,image acquisition rate,battery life,field of view,and possible optical enhancements.More recently,the use of VCE has been extended to exploring the colon.Within the last 5 years,tremendous developments have been made toward increasing the capabilities of the colon capsule.Although colon capsule cannot be proposed as a first-line colorectal cancer screening procedure,colon capsule may be used in patients with incomplete colonoscopy or in patients who are unwilling to undergo colonoscopy.In the near future,new technological developments will improve the diagnostic yield of VCE and broaden its therapeutic capabilities. | Simon Bouchard Mostafa Ibrahim Andre Van Gossum | 2014 | World Journal of Gastroenterology2014，20，46： | 12 |
| 2 | Evaluation of Fujinon intelligent chromo endoscopy-assisted capsule endoscopy in patients with obscure gastroenterology bleeding显示文摘AIM:To investigate the potential benef it of Fujinon in-telligent chromo endoscopy(FICE)-assisted small bowel capsule endoscopy(SBCE)for detection and character-ization of small bowel lesions in patients with obscure gastroenterology bleeding(OGIB).METHODS:The SBCE examinations(Pillcam SB2,Giv-en Imaging Ltd)were retrospectively analyzed by two GI fellows(observers)with and without FICE enhance-ment.Randomization was such that a fellow did not assess the same examination with and without FICE enhancement.The senior consultant described f indings as P0,P1 and P2 lesions(non-pathological,intermedi-ate bleed potential,high bleed potential),which were considered as reference f indings.Main outcome mea-surements:Inter-observer correlation was calculated using kappa statistics.Sensitivity and specif icity for P2 lesions was calculated for FICE and white light SBCE.RESULTS:In 60 patients,the intra-class kappa cor-relations between the observers and reference f indings were 0.88 and 0.92(P2),0.61 and 0.79(P1),for SBCE using FICE and white light,respectively.Overall 157 le-sions were diagnosed using FICE as compared to 114 with white light SBCE(P = 0.15).For P2 lesions,the sensitivity was 94% vs 97% and specif icity was 95% vs 96% for FICE and white light,respectively.Five(P2 le-sions)out of 55 arterio-venous malformations could be better characterized by FICE as compared to white light SBCE.Significantly more P0 lesions were diagnosed when FICE was used as compared to white light(39 vs 8,P < 0.001).CONCLUSION:FICE was not better than white light for diagnosing and characterizing signif icant lesions on SBCE for OGIB.FICE detected signif icantly more non-pathological lesions.Nevertheless,some vascular le-sions could be more accurately characterized with FICE as compared to white light SBCE. | Tarun Gupta Mostafa Ibrahim Jacques Deviere André Van Gossum | 2011 | World Journal of Gastroenterology2011，17，41： | 8 |
| 3 | Gut Failure in the ICU显示文摘 | Francesco Puleo Marianna Arvanitakis André Van Gossum Jean-Charles Preiser | 2011 | Semin Respir Crit Care Med2011，，05： | 2 |
| 4 | ESPEN Guidelines on Enteral Nutrition: Gastroenterology显示文摘 | H. Lochs C. Dejong F. Hammarqvist X. Hebuterne M. Leon-Sanz T. Schütz W. van Gemert A. van Gossum L. Valentini H. Lübke S. Bischoff N. Engelmann P. Thul | 2006 | Clinical Nutrition2006，，2： | 2 |
| 5 | Obscure digestive bleeding显示文摘 | Van Gossum A | 2001 | Best Pratt Res Clin Gastroenterol2001，15，1： | 1 |
| 6 | Gut failure in the ICU 显示文摘 | Puleo F Arvanitakis M Van Gossum A | 2011 | Semin Respir Crit Care Med2011，32，5： | 1 |
| 7 | Gut failure in the ICU 显示文摘 | Puleo F Arvanitakis M Van Gossum A | 2011 | Semin Respir Crit Care Med2011，32，5： | 1 |
| 8 | Thiobarbituric acid reactive substances as a marker of oxidative stress in healthy subjects and in patients with impairment in trace element status显示文摘 | Wasowicz W Nève J van Gossum J | 1993 | Clinical Nutrition1993，2，： | 1 |
| 9 | Negative frequen- cy-dependent selection or alternative reproductive tactics: maintenance of female polymorphism in natural populations显示文摘 | Iserbyt A Bots J Gossum H V 2013 | 2013 | BMC Evolutionary Biology2013，13，27： | 1 |
| 10 | Gut failure in the ICU 显示文摘 | Puleo F Arvanitakis M Van Gossum A | 2011 | Semin Respir Crit Care Med2011，32，5： | 1 |
| 11 | Inflammatory bowel disease in spouses and their offspring显示文摘 | David Laharie Stéphane Debeugny Marc Peeters André Van Gossum Corinne Gower-Rousseau Jacques Bélahe René Fiasse Jean-Louis Dupas Eric Lerebours Sandrine Piotte Antoine Cortot Séverine Vermeire Bruno Grandbastien Jean-Frédéric Colombel | 2001 | Gastroenterology2001，，： | 1 |
| 12 | Multicenter clinical trial of probiotics LA1 ) on early endoscopic recurrence of Crohn's disease after ileo- caecal resection显示文摘 | Van Gossum A Dewit O randomized - controlled ( lactobacillus johnsonii Louis E | 2007 | Inflamm Bowel Dis2007，13，2： | 1 |
| 13 | Spontaneous secretion of interferon γ and interleakin 4 by human intraepithelial and lamina propria gut lymphocytes 显示文摘 | Carol M Lambrechts A Van Gossum A | 1998 | Gut1998，42，5： | 1 |
| 14 | Gut failure in the ICU 显示文摘 | Puleo F Arvanitakis M Van Gossum A at al | 2011 | Semin Respir Crit Care Med2011，32，5： | 1 |
| 15 | ESPEN guidelines on parenteral nutrition: gastroenterology显示文摘 | Gossum AV Cabre E H6buterne X | 2009 | Clinical Nutri- tion2009，28，4： | 1 |
| 16 | Multicenter randomized-controlled clinical trial of probiotics (LactobaciUus johnsonii,LA 1) on early endoscopic recurrence of Crohn's disease after lleocaeca1 resection显示文摘 | Van Gossum A Dewit O Louis E | 2007 | Inflamm Bowel Dis2007，13，2： | 1 |
| 17 | Gut failure in the ICU显示文摘 | Puleo F Arvanitakis M Van Gossum A | 2011 | Semin Respir Crit Care Med2011，32，5： | 1 |
| 18 | Capsule endoscopy versus colonoscopy for the detection of polyps and cancer显示文摘 | Van Gossum A Munoz Navas M Femandez-Urien I | 2009 | N Engl J Med2009，361，3： | 1 |
| 19 | Obscure digestive bleeding显示文摘 | Van Gossum A | 2001 | Best Pract Res Clin Gastroenterol2001，15，1： | 1 |
| 20 | Second-generation colon capsule endoscopy compared with colonoscopy显示文摘 | Cristiano Spada Cesare Hassan Miguel Munoz-Navas Horst Neuhaus Jacques Deviere Paul Fockens Emmanuel Coron Gerard Gay Ervin Toth Maria Elena Riccioni Cristina Carretero Jean P. Charton Andrè Van Gossum Carolien A. Wientjes Sylvie Sacher-Huvelin Michel Del | 2011 | Gastrointestinal Endoscopy2011，，3： | 1 |
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