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15篇 您的检索式:作者名="Goulette"
    题名 作者 年代 出处 被引量
1STAT3 cleav- age by caspases: Impact on full-length STAT3 expression, frag- ment formation, and transcriptional activity显示文摘Dalnowski J W Goulette F A Guan V J 2006J Biol Chem2006,281,17:1
2Evaluation of Corona reactors of several geometries for a plasma assisted nitrogen oxide emission reduction device显示文摘Darrell Herling Monty Smith Mark Hemingway David Goulette 2000SAE Paper2000,,:1
3Taurolidine:cytotoxic and mechanistic evaluation of a novel antineoplastic agent显示文摘Calabresi P Goulette FA Darnowski JW 2001Cancer Res2001,61,:1
4Amifostine cytotoxicity and induction of apoptosis in a human myelodysplastic cell line显示文摘RIBIZZI I DARNOWSKI J W GOULETTE F A 2000Leuk Res2000,24,:1
5Mechanistic and antineoplastic evaluation of taurolidine in the DU145 model of human prostate cancer 显示文摘Darnowski JW Goulette FA Cousens LP 2004Caneer Chemother Pharmacol2004,54,3:1
6Taurolidine: cytotoxic and mechanistic evaluation of a novel antineoplastic agent 显示文摘Calabresi P Goulette FA Darnowski JW 2001Cancer Res2001,61,18:1
7Amifostine cytotoxicity and induction of apoptosis in a human myelodysplastic cell line显示文摘Ribizzi I Darnowski JW Goulette FA 0,,6:1
8Thrombospondin-1 plus irinotecan:a novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor xenografts in mice显示文摘Allegrini G Goulette FA Darnowski JW 2004Cancer Chemother Pharmacol2004,53,3:1
9Taurolidine:cytotoxic and mechanistic evaluation of a novel antineoplastic agent显示文摘Calabresi P Goulette FA Darnowski JW 2001Cancer research2001,61,18:1
10Mechanistic and antineoplastic evaluation of taturolidine in the DU145 model of human prostate cancer显示文摘Damowski JW Goulette FA Cousens LP Chatterjee D Calabresi P 2004Cancer Chemother Pharmacol2004,54,:1
11Taurolidine: cytotoxic and mechanistic evaluation of a novel antineoplastic agent显示文摘Calabresi P Goulette FA Darnowski JW 2001Cancer Res2001,61,:1
12An integrat- ed on-board laser range sensing system for on-the-way city and road modelling显示文摘Goulette F Nashashibi F Abuhadrous I 2006International Archives of Pho- togrammetry Remote Sensing and Spatial Information Sciences2006,36,1:1
13Mechanistic and antineoplastic evaluation of taurolidine in the DU145 model of human prostate cancer显示文摘 Goulette FA Cousens LP 2004Cancer Chemother Pharmacol2004,54,:1
14Taurolidine : cytotoxic and mechanistic evaluation of a novel antineoplastic agent显示文摘Calabresi P Goulette FA Darnowski JW 2001Cancer Res2001,61,:1
15Dietary Pterostilbene Inhibited Colonic Inflammation in Dextran-Sodium-Sulfate-Treated Mice:A Perspective of Gut Microbiota显示文摘Dietary interventions based on the use of bioactive nutraceuticals might offer an effective adjuvant therapeutic and preventive method for inflammatory bowel disease by reshaping colitis-associated bacterial dysbiosis.The current study aimed to determine the antiinflammatory effect of pterostilbene(PTE,a methylated derivative of resveratrol)and its potential modulatory roles in gut microbiota in a dextran sodium sulfate(DSS)-induced colitis mouse model.Our results supported our hypothesis that dietary PTE exerted protective effects against colonic inflammation;evidenced by the reduced colonic tissue damage,decreased disease activity index,and lowered production of pro-inflammatory cytokines such as interferon gamma,interleukin(IL)-2,IL-4,and IL-6 in the colon of DSS-treated mice.Moreover,a-diversity analysis indicated that dietary PTE significantly improved gut microbial evenness and diversity.Noteworthy,PTE modified gut microbiota composition toward a healthier profile by boosting the richness of Bifidobacterium and decreasing the distribution of pathogenic Bilophila and Rc4-4.Pearson correlation analysis also revealed strong associations between the shifting of gut microbiota and expression of inflammatory cytokines in the colon.Overall,our study demonstrated that dietary PTE alleviated the severity of colitis in DSS-treated mice and gut microbiota may play an indispensable role in this process mechanistically.Fang Li Qi Wang Yanhui Han Mingyue Song Xiaokun Cai Timothy Goulette Hang Xiao 2021Infectious Microbes & Diseases2021,3,1:0
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