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| 1 | Inhibition of metastasis-associated lung adenocarcinoma transcript 1 in CaSki human cervical cancer cells suppresses cell proliferation and invasion显示文摘(MALAT1 ) 联系转移的肺腺癌抄本 1 被建议是一长(7 kb ) 非编码的 RNA。MALAT1 是在许多人的癌的 overexpressed,但是它的功能仍然保持未知。在人的颈的癌症前进调查 MALAT1 的角色,我们设计了并且使用了短发卡 RNA 在 CaSki 房间禁止 MALAT1 表示并且在房间增长和侵略上验证了它的效果。在基因表示的变化被反向的 transcriptasepolymerase 链反应分析。我们的数据证明 MALAT1 通过基因表示的规定涉及颈的癌症房间生长,房间周期前进,和侵略,例如 caspase-3, -8, Bax, Bcl-2,和 Bcl-xL,建议 MALAT1 能有在颈的癌症生物学的重要含意。我们的调查结果在颈的癌症前进说明 MALAT1 的生物意义并且提供 MALAT1 可以在人的颈的癌症的预防作为一个治疗学的目标服务的新奇证据。 | Fengjie Guo Yalin Li Yan Liu Jiajia Wang Yuehui Li Guancheng Li | 2010 | Acta Biochimica et Biophysica Sinica2010，42，3： | 89 |
| 2 | Novel Water-Based Drilling and Completion Fluid Technology to Improve Wellbore Quality During Drilling and Protect Unconventional Reservoirs显示文摘The efficient exploration and development of unconventional oil and gas are critical for increasing the self-sufficiency of oil and gas supplies in China.However,such operations continue to face serious problems(e.g.,borehole collapse,loss,and high friction),and associated formation damage can severely impact well completion rates,increase costs,and reduce efficiencies.Water-based drilling fluids possess certain advantages over oil-based drilling fluids(OBDFs)and may offer lasting solutions to resolve the aforementioned issues.However,a significant breakthrough with this material has not yet been made,and major technical problems continue to hinder the economic and large-scale development of unconventional oil and gas.Here,the international frontier external method,which only improves drilling fluid inhibition and lubricity,is expanded into an internal-external technique that improves the overall wellbore quality during drilling.Bionic technologies are introduced into the chemical material synthesis process to imitate the activity of life.A novel drilling and completion fluid technique was developed to improve wellbore quality during drilling and safeguard formation integrity.Macroscopic and microscopic analyses indicated that in terms of wellbore stability,lubricity,and formation protection,this approach could outperform methods that use typical OBDFs.The proposed method also achieves a classification upgrade from environmentally protective drilling fluid to an ecologically friendly drilling fluid.The developed technology was verified in more than 1000 unconventional oil and gas wells in China,and the results indicate significant alleviation of the formation damage attributed to borehole collapse,loss,and high friction.It has been recognized as an effective core technology for exploiting unconventional oil and gas resources.This study introduces a novel research direction for formation protection technology and demonstrates that observations and learning from the natural world can provide an inexhaustible source of ideas and inspire the creation of original materials,technologies,and theories for petroleum engineering. | Guancheng Jiang Jinsheng Sun Yinbo He Kaixiao Cui Tengfei Dong Lili Yang Xukun Yang Xingxing Wang | 2022 | Engineering2022，，11： | 11 |
| 3 | Evaluation of gas wettability and its effects on fluid distribution and fluid flow in porous media显示文摘The special gas wettability phenomenon of reservoir rocks has been recognized by more and more researchers.It has a significant effect on efficient development of unconventional reservoirs.First,based on the preferentially gas-covered ability and surface free energy changes,definition and evaluation methods have been established.Second,a method for altering rock wettability and its mechanisms have been studied,surface oriented phenomena of functional groups with low surface energy are the fundamental reason for gas wettability alteration of rock.Third,the effect of gas wettability on the surface energy,electrical properties and dilatability are investigated.Last,the effects of gas wettability on capillary pressure,oil/gas/water distribution and flow are investigated with capillary tubes and etchedglass network models.The gas wettability theory of reservoir rocks has been initially established,which provides theoretical support for the efficient production of unconventional reservoirs and has great significance. | Jiang Guancheng Li Yingying Zhang Min | 2013 | Petroleum Science2013，10，4： | 10 |
| 4 | The role of MALAT1 correlates with HPV in cervical cancer显示文摘 | Yan Jiang Yuehui Li Shujuan Fang Binyuan Jiang Changfei Qin Pingli Xie Guohua Zhou Guancheng Li | 2014 | Oncology Letters2014，，6： | 3 |
| 5 | DERIVATION AND INTEGRAL SLIDING MODE VARIABLE STRUCTURE CONTROL OF HYDRAULIC VELOCITY TRACKING SYSTEM显示文摘The velocity tracking control of a hydraulic servo system is studied. Since the dynamics of the system are highly nonlinear and have large extent of model uncertainties, such as big changes in load and parameters, a derivation and integral sliding mode variable structure control scheme (DI-SVSC) is proposed. An integral controller is introduced to avoid the assumption that the derivative of desired signal must be known in conventional sliding mode variable structure control, a nonlinear derivation controller is used to weaken the chattering of system. The design method of switching function in integral sliding mode control, nonlinear derivation coefficient and controllers of DI-SVSC is presented respectively. Simulation shows that the control approach is of nice robustness and improves velocity tracking accuracy considerably. | WeiJianhua GuanCheng | 2005 | Chinese Journal of Mechanical Engineering2005，18，2： | 3 |
| 6 | Construction of cDNA Library from NPC Tissue and Screening of Antigenic Genes显示文摘构造鼻咽的癌(NPC ) 的 cDNA 图书馆并且获得联系的 NPC 或从它的特定的抗原,我们使用了一个强大的新方法识别得到体液的有免疫力的反应的抗原,它是 SEREX (由 recombinant cDNA 表示图书馆的抗原的血清学的鉴定) 。NPC 病人的自体同源的浆液被用来在人的 NPC 织物 cDNA 图书馆屏蔽反应克隆由 3.64 瑹獥 ? 呃 ? 捡楴楶祴 ? 湡 ? 组成了畮扭牥漠吗?? | Jun Shu Xiaojuan He Guancheng Li | 2006 | Cellular & Molecular Immunology2006，3，1： | 3 |
| 7 | Inhibiting effect of dopamine adsorption and polymerization on hydrated swelling of montmorillonite显示文摘 | Xuan Yang Jiang Guancheng Li Yingying | 2013 | Colloids Surf A2013，422，： | 1 |
| 8 | Removal efficiency of heavy oil by free and immobilised microorganisms on laboratory‐scale显示文摘 | Mutai Bao Qingguo Chen Yuanjiao Gong Yiming Li Haifeng Wang Guancheng Jiang | 2011 | Can. J. Chem. Eng2011，，1： | 1 |
| 9 | A clinical trial of active immunotherapy anti-idiotypic vaccine in nasopharyngeal carcinoma patients显示文摘 | Li Guancheng Xie Lu Zhou Guohua | 2002 | Chin Med J2002，115，4： | 1 |
| 10 | Identification of HTA as a novel-specific marker for human hepatocellular carcinoma显示文摘 | Yan Liu Yuehui Li Fengjie Guo Miao Dai Jiajia Wang Jinyue Hu Guancheng Li | 2010 | Journal of Cancer Research and Clinical Oncology2010，，8： | 1 |
| 11 | Calixarene-supported hexadysprosium cluster showing single molecule magnet behavior显示文摘The syntheses, crystal structures, magnetic and luminescent properties of three isomorphous compounds [Ln III 6 (μ 4-O) 2 (C4A) 2-(NO 3 ) 2 (HCOO) 2 (CH 3 O) 2 (DMF) 4 (CH 3 OH) 4 ] (Ln = Gd (1), Tb (2) and Dy (3); H 4 C4A = p-tert-butylcalix[4]arene) are reported. These three compounds are featured with the sandwich-like units constructed by two tail-to-tail calixarene molecules and an in-between Ln III 6 octahedron. The Dy III compound exhibits both single molecule magnet behavior and photoluminescence. | BI YanFeng XU GuanCheng LIAO WuPing DU ShangChao DENG RuiPing WANG BingWu | 2012 | Science China Chemistry2012，55，6： | 1 |
| 12 | Carbon dioxide/calcium oxide responsive behavior and application potential of amine emulsion显示文摘Green and low cost CO_(2) and CaO were used to stimulate amine emulsions to reveal the responsive behavior of amine emulsions.On this basis,oil-based drilling fluids responsive to CO_(2) and CaO were formulated and their properties were evaluated.The results showed that the amine emulsions inversed from water-in-oil state to oil-in-water state readily and their rheological behavior underwent transitions of decreasing,rising again and decreasing again via induction by CO_(2).These CO_(2) responsive behaviors could be reversed by CaO.Oil-based drilling fluids prepared based on the amine emulsions with oil-water volume ratios of 50:50 to 70:30,densities of 1.4-2.0 g/cm^(3) had good rheological and filtration properties at 160℃;and be readily cleaned up using CO_(2) bubbling.The useless solid phase with low density could be removed efficiently via reducing the viscosity of emulsion by CO_(2) and the residual liquid phase could be restored to the original state by CaO and reused to prepare drilling fluid.The mechanisms analysis indicated that CO_(2)/CaO induced the reversible conversion between amine emulsifiers and their salts,which enabled the reversible regulation of both the hydrophilic-lipophilic balance of amine emulsifiers and the emulsion particles’size and finally caused the controllable-reversion of the form and rheology of amine emulsion. | REN Yanjun LU Yanyan JIANG Guancheng ZHOU Wenjing WU Liansong YAO Rugang XIE Shuixiang | 2021 | Petroleum Exploration and Development2021，48，5： | 1 |
| 13 | Development of key additives for organoclay-free oil-based drilling mud and system performance evaluation显示文摘Traditional oil-based drilling muds(OBMs) have a relatively high solid content, which is detrimental to penetration rate increase and reservoir protection. Aimed at solving this problem, an organoclay-free OBM system was studied, the synthesis methods and functioning mechanism of key additives were introduced, and performance evaluation of the system was performed. The rheology modifier was prepared by reacting a dimer fatty acid with diethanolamine, the primary emulsifier was made by oxidation and addition reaction of fatty acids, the secondary emulsifier was made by amidation of a fatty acid, and finally the fluid loss additive of water-soluble acrylic resin was synthesized by introducing acrylic acid into styrene/butyl acrylate polymerization. The rheology modifier could enhance the attraction between droplets, particles in the emulsion via intermolecular hydrogen bonding and improve the shear stress by forming a three-dimensional network structure in the emulsion. Lab experimental results show that the organoclay-free OBM could tolerate temperatures up to 220 ?C and HTHP filtration is less than 5 m L. Compared with the traditional OBMs, the organoclay-free OBM has low plastic viscosity, high shear stress, high ratio of dynamic shear force to plastic viscosity and high permeability recovery, which are beneficial to penetration rate increase, hole cleaning and reservoir protection. | SUN Jinsheng HUANG Xianbin JIANG Guancheng LYU Kaihe LIU Jingping DAI Zhiwen | 2018 | Petroleum Exploration and Development2018，45，4： | 1 |
| 14 | Effectof water-based drilling fluid components on filter cakestructure 显示文摘 | YAO Rugang JIANG Guancheng LI Wei | 2014 | Powder Technology2014，262，： | 1 |
| 15 | The effect of inorganic salt on the structure of filter cake of water based drilling fluid显示文摘 | YAO Rugang JIANG Guancheng YE Longyun | 2014 | Proceedings2014，，01： | 1 |
| 16 | Biodegradation of partially hydrolyzed polyacrylamide by bacteria isolated from production water after polymer flooding in an oil field显示文摘 | Mutai Bao Qingguo Chen Yiming Li Guancheng Jiang | 2010 | Journal of Hazardous Materials2010，，1： | 1 |
| 17 | Methylenetetrahydrofolate reductase C677T gene polymorphism and colorectalcancer risk: A case-control study显示文摘 | Guancheng Yin Hanxin Ming Xiao Zheng Yi Xuan Jianwei Liang Xing Jin | 2012 | Oncology Letters2012，，2： | 1 |
| 18 | Inhibiting effect of dopamine adsorption and polymerization on hydrated swelling of montmorillonite显示文摘 | XUAN Yang JIANG Guancheng LI Yingying | 2013 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2013，422，： | 1 |
| 19 | Tuning electrical properties of transparent p-NiO/n-MgZnO hetero- junctions with band gap engineering of MgZnO显示文摘 | Chen Xinman Ruan Kaibin Wu Guancheng | 2008 | Appl Phys Lett2008，，： | 1 |
| 20 | Study on Economic growth,Urbanization and Sustainable Utilization of Cultivated Land in China显示文摘By means of the dynamic regression model, this paper analyzes the relationships among economic growth, urbanization and changes of cultivated land in China, finds that the ratio of cultivated land occupied by economic growth is decreasing with social and economic growth. And, based on that, some policy suggestions on how to promote the sustainable use of cultivated land in China are put forward. | Wu Qun,Guo Guancheng & Fan LiCollege of Land Management,Nanjing Agricultural University,Nanjing,210095,China | 2004 | Chinese Journal of Population,Resources and Environment2004，2，2： | 1 |
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