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| 1 | Detection of HBV DNA and its existence status in liver tissues and peripheral blood lymphocytes from chronic hepatitis B patients显示文摘INTRODUCTIONCumulativeclinicalandexperimentalevidenceindicatesthathostimmuneresponsestohepatitisBvirus(HBV)areresponsibleforl... | TANG Ren Xian, GAO Feng Guang, ZENG Ling Yu, WANG Ying Wei and WANG Yu Long | 1999 | World Journal of Gastroenterology1999，5，4： | 27 |
| 2 | Prevalence and characteristics of MAFLD in Chinese adults aged 40 years or older:A community-based study显示文摘Background: Nonalcoholic fatty liver disease(NAFLD) was recently proposed to be renamed metabolic dysfunction-associated fatty liver disease(MAFLD) with the diagnostic criteria revised. We investigated the similarities and differences in the prevalence and clinical characteristics of MAFLD and NAFLD in Chinese adults. Methods: A cross-sectional study of 9980 Chinese individuals aged 40 years or older was performed between 2011 and 2012 using randomized, stratifed cluster sampling in Shanghai, China. A detailed questionnaire and the results of abdominal ultrasonography, a standardized 2-h 75-g oral glucose tolerance test and blood biochemical examinations were collected. Results: A total of 9927 subjects were included in this study. The prevalence of MAFLD(40.3%) was significantly higher than that of NAFLD(36.9%)( P < 0.05). MAFLD was highly prevalent in type 2 diabetes mellitus(T2DM)(53.8%), impaired fasting glucose(35.7%) and impaired glucose tolerance(40.9%). High risk of advanced fbrosis based on fbrosis-4 was highly prevalent(14.7%) in lean MAFLD with T2DM. Among 9927 subjects, 3481(35.1%) fulflled the diagnostic criteria for MAFLD and NAFLD(MAFLD + NAFLD +), 521(5.2%) MAFLD + NAFLD-, and 181(1.8%) MAFLD-NAFLD +. The MAFLD + NAFLD-group had more signifcant metabolic disorders than those in the MAFLD + NAFLD + group(all P < 0.05). Among MAFLD-NAFLD + subjects, 82.9% had metabolic disorders. Conclusions: The new defnition of MAFLD may better reflect the pathogenesis related to metabolism. Future research should focus on studying the natural history, pathogenesis and treatment effectivity of the overlap and non-overlap of NAFLD and MAFLD subjects. | Jing Zeng Li Qin Qian Jin Rui-Xu Yang Guang Ning Qing Su Zhen Yang Jian-Gao Fan | 2022 | Hepatobiliary & Pancreatic Diseases International2022，21，2： | 13 |
| 3 | Chinese Medicine Sequential Therapy Improves Pregnancy Outcomes after Surgery for Endometriosis-Associated Infertility: A Multicenter Randomized Double-blind Placebo Parallel Controlled Clinical Trial显示文摘Objective:To evaluate the efficacy and safety of Chinese medicine(CM)improving pregnancy outcomes after surgery for endometriosis-associated infertility.Methods:A multicenter,randomized,doubleblind placebo parallel controlled clinical trial was designed.A total of 202 patients who had laparoscopy for endometriosis-associated infertility with qi stagnation and blood stasis syndrome were included and randomly divided into the CM treatment group and placebo control group at a ratio of 1:1 using a central block randomization from May 2014 to September 2017,101 patients in each group.The two groups received continuous intervention at 1–5 days after surgery,for 6 menstrual cycles.Before ovulation,the CM group was treated Huoxue Xiaoyi Granule(活血消异颗粒);after ovulation,Bushen Zhuyun Granule(补肾助孕颗粒)was involved.The control group was treated with placebo.Transvaginal ultrasonography was performed every menstrual cycle during the treatment,and female hormone levels in the follicular and luteal phases were measured during the 1 st,3 rd and 6 th menstrual cycles.The analysis was continued until pregnancy.The primary outcomes were clinical pregnancy rate and pregnancy outcome,and the secondary outcomes were follicular development and endometrial receptivity.Safety evaluations were performed before and after treatment.Results:(1)Clinical pregnancy and live birth rates:the clinical pregnancy and live birth rates of the CM group were significantly higher than those of the placebo group[44.6%(45/101)vs.29.7%(30/101),34.7%(35/101)vs.20.8%(21/101),both P<0.05].(2)Follicle development:the incidence of dominant follicles,rate of cumulative cycle ovulation,and rate of cumulative cycle mature follicle ovulation were significantly higher in the CM group than those in the placebo group[93.8%(350/373)vs.89.5%(341/381),80.4%(275/342)vs.69.1%(253/366),65.8%(181/275)vs 56.1%(142/253),P<0.05 or P<0.01]).The incidence of cumulative cycle luteinized unruptured follicle syndrome was significantly lower in the CM group than in the placebo group[11.7%(40/342)vs.17.8%(65/366),P<0.05).(3)Endometrial receptivity:after treatment,both endometrial types and endometrial blood flow types in the CM group were mainly types A and B,while those in the placebo group were mainly types B and C,with a significant difference between the two groups(both P<0.05).(4)Adverse events:the incidence of adverse events between the two groups was not significantly different(P>0.05).Conclusion:Strategies for activating blood circulation-regulating Gan(Liver)-tonifying Shen(Kidney)sequential therapy can effectively improve the clinical pregnancy rate and live birth rate of endometriosis-associated infertility with qi stagnation and blood stasis after laparoscopy,improve follicular development,promote ovulation,improve endometrial receptivity,while being a safe treatment option.(Trial registration No.NCT02676713). | ZHAO Rui-hua LIU Yong LU Dan WU Ying WANG Xiao-yun LI Wei-li ZENG Cheng MENG Qing-wei LIAN Feng-mei ZHOU Jun SHI Yun SUN Wei-wei HAN Qian TANG Yi SHI Guang | 2020 | Chinese Journal of Integrative Medicine2020，26，2： | 13 |
| 4 | The impact of climate change on forest fire danger rating in China’s boreal forest显示文摘The Great Xing'an Mountains boreal forests were focused on in the northeastern China.The simulated future climate scenarios of IPCC SRES A2a and B2a for both the baseline period of 1961-1990 and the future scenario periods were downscaled by the Delta Method and the Weather Generator to produce daily weather data.After the verification with local weather and fire data,the Canadian Forest Fire Weather Index System was used to assess the forest fire weather situation under climate change in the study region.An increasing trend of fire weather severity was found over the 21st century in the study region under the both future climate change scenarios,compared to the 1961-1990 baseline period.The annual mean/maximum fire weather index was predicted to rise continuously during 2010-2099,and by the end of the 21st century it is predicted to rise by 22%-52% across much of China's boreal forest.The significant increases were predicted in the spring from of April to June and in the summer from July to August.In the summer,the fire weather index was predicted to be higher than the current index by as much as 148% by the end of the 21st century.Under the scenarios of SRES A2a and B2a,both the chance of extremely high fire danger occurrence and the number of days of extremely high fire danger occurrence was predicted to increase in the study region.It is anticipated that the number of extremely high fire danger days would increase from 44 days in 1980s to 53-75 days by the end of the 21st century. | YANG Guang DI Xue-ying GUO Qing-xi SHU Zhan ZENG Tao YU Hong-zhou WANG Chao | 2011 | Journal of Forestry Research2011，22，2： | 12 |
| 5 | Allergy-related Evidences in Relation to Serum IgE:Data from the China State Key Laboratory of Respiratory Disease,2008-2013显示文摘Objective To investigate the serum total IgE(tlgE) and specific IgE(slgE) to common allergens among allergic patients in Guangzhou,China.Methods 7 085 patients were examined for tlgE and slgE to 15 allergens,based on the protocols of reversed enzyme allergosorbent test and the sandwich enzyme-linked immunosorbent assay.Results 3 758(53.04%) patients tested positive for tlgE,and 4 640(65.49%) for slgE.Der pteronyssinus,Der farinae,eggs,and cow's milk were the most common allergens leading to higher positive rates of slgE responses.Several peaks of sensitization were:Der pteronyssinus,Der farinae,and Blomia tropicalis at age 10-12;cow's milk at age below 3;eggs at age 4-6.The mean level and positive rate of tlgE tended to increase in subjects sensitized to more allergens.Sensitization to Der pteronyssinus(OR,1.6;P<0.05),Der farinae(OR,1.5;P<0.05),Blomia tropicalis(OR,1.4;P<0.05),Blattella germanica(OR,1.5;P<0.05),cow's milk(OR,1.3;P<0.05),and soy beans(OR,2.0;P<0.05) were independently correlated with allergy-related conditions in preliminary diagnosis.Conclusion The major allergens in Guangzhou include Der pteronyssinus,Der farinae,cow's milk,and eggs.Sensitization to these allergens appears to be predictors of allergy-related disorder. | SUN Bao Qing CHEN De Hui ZHENG Pei Yan HUANG Hui Min LUO Wen Ting ZENG Guang Qiao ZHANG Xiao Wen | 2014 | Biomedical and Environmental Sciences2014，27，7： | 11 |
| 6 | A trinomial type of σ-LFSR oriented toward software implementation显示文摘In this paper, we introduce a new type of feedback shift register based on words, called σ-linear feedback shift register (σ-LFSR) which can make full use of the instructions of modern CPUs so that we can find good σ-LFSR with simple structure and fast software implementation. After analysis, we find a class of simple σ-LFSR with maximal period and give an algorithm of searching for those σ-LFSRs. As a result, we provide a new optional fast component in the design of modern word-based stream ciphers. | ZENG Guang HE KaiCheng HAN WenBao | 2007 | Science in China(Series F)2007，50，3： | 11 |
| 7 | Prediction of the amount of urban waste solids by applying a gray theoretical model显示文摘Urban waste solids are now becoming one of the most crucial environmental problems. There are several different kinds of technologies normally used for waste solids disposal, among which landfill is more favorable in China than others, especially for urban waste solids. Most of the design works up to now are based on a roughly estimation of the amount of urban waste solids without any theoretical support, which lead to a series problems. To meet the basic information requirements for the design work, the amount of the urban waste solids was predicted in this research by applying the gray theoretical model GM (1,1) through non linear differential equation simulation. The model parameters were estimated with the least square method (LSM) by running a certain MATALAB program, and the hypothesis test results show that the residual between the prediction value and the actual value approximately comply with the normal distribution N (0,0 21 2), and the probability of the residual within the range (-0 17, 0 19) is more than 95%, which indicate obviously that the model can be well used for the prediction of the amount of waste solids and those had been already testified by the latest two years data about the urban waste solids from Loudi City of China. With this model, the predicted amount of the waste solids produced in Loudi City in the next 30 years is 8049000 ton in total. | LI Xiao ming, ZENG Guang ming, WANG Ming, LIU Jin jin (Department of Environmental Science and Technology, Hunan University, Changsha 410082, China. | 2003 | Journal of Environmental Sciences2003，15，1： | 11 |
| 8 | High quality reference genome of drumstick tree(Moringa oleifera Lam.), a potential perennial crop显示文摘The drumstick tree(Moringa oleifera Lam.) is a perennial crop that has gained popularity in certain developing countries for its high-nutrition content and adaptability to arid and semi-arid environments. Here we report a high-quality draft genome sequence of M. oleifera. This assembly represents 91.78% of the estimated genome size and contains 19,465 protein-coding genes. Comparative genomic analysis between M. oleifera and related woody plant genomes helps clarify the general evolution of this species, while the identification of several species-specific gene families and positively selected genes in M. oleifera may help identify genes related to M. oleifera's high protein content, fast-growth, heat and stress tolerance. This reference genome greatly extends the basic research on M. oleifera, and may further promote applying genomics to enhanced breeding and improvement of M. oleifera. | TIAN Yang ZENG Yan ZHANG Jing YANG Cheng Guang YAN Liang WANG XuanJun SHI ChongYing XIE Jing DAI TianYi PENG Lei ZENG HUAN Yu XU An Ni HUANG YeWei ZHANG JiaJin MA Xiao DONG Yang HAO ShuMei SHENG Jun | 2015 | Science China(Life Sciences)2015，58，7： | 10 |
| 9 | Breaking 12% efficiency in flexible organic solar cells by using a composite electrode显示文摘The performance of flexible organic solar cells(OSCs)significantly relies on the quality of transparent flexible electrode.Here,we used silver nanowires(AgNWs)with various weight ratios to dope high-conductive poly(3,4-ethylenedioxythiophene):polystyrene sulfonate(PH1000)to optimize the optical and electronic properties of PH1000 film.A high-quality flexible composite electrode PET/Ag-mesh/PH1000:AgNWs-20 with smooth surface,a low sheet resistance of 6Ω/sq and a high transmittance of 86%at 550-nm wavelength was obtained by doping 20 wt%AgNWs to PH1000(PH1000:AgNWs-20).The flexible OSCs based on the PET/Ag-mesh/PH1000:AgNWs-20 electrode delivered a power conversion efficiency(PCE)of12.07%with an open circuit voltage(Voc)of 0.826 V,a short-circuit current density(Jsc)of 20.90 m A/cm2and a fill factor(FF)of69.87%,which is the highest reported PCE for the flexible indium-tin oxide(ITO)-free OSCs.This work demonstrated that the flexible composite electrodes of PET/Ag-mesh/PH1000:AgNWs are promising alternatives for the conventional PET/ITO electrode,and open a new avenue for developing high-performance flexible transparent electrode for optoelectronic devices. | Guang Zeng Jingwen Zhang Xiaobin Chen Hongwei Gu Yaowen Li Yongfang Li | 2019 | Science China Chemistry2019，62，7： | 9 |
| 10 | Highly efficient and precise base editing in discarded human tripronuclear embryos显示文摘 | Guanglei Li Yajing Liu Yanting Zeng Jianan Li Lijie Wang Guang Yang Dunjin Chen Xiaoyun Shang Jia Chen Xingxu Huang Jianqiao Liu | 2017 | Protein & Cell2017，8，10： | 8 |
| 11 | Oxyphyllones A and B,novel sesquiterpenes with an unusual 4,5-secoeudesmane skeleton from Alpinia oxyphylla显示文摘二新奇 4,5-secoeudesmane sesquiterpenoids, oxyphyllones A (1 ) 和 B (2 ) 从 Alpinia oxyphylla 的水果被孤立。他们的结构被包括 1D 和 2D NMR 系列的分光镜的方法建立。这二混合物是有在 Zingiberaceae 的家庭的一架 4,5-secoeudesmane 骨骼的自然地发生的 sesquiterpenoids 的第一个例子, oxyphyllone A (1 ) 是 13-norsesquiterpenoid 的第一种 4,5-secoeudesmane 类型。1 和 2 展出了的混合物对三个癌症房间的 cytotoxicities 都不在 10 μ 排队; g/mL。 | Jun Ju Xu Ning Hua Tan Jiang Xiong Abiodun Humphrey Adebayo Hong Jin Han Guang Zhi Zeng Chang Jiu Ji Yu Mei Zhang Mei Ju Zhu | 2009 | Chinese Chemical Letters2009，20，8： | 7 |
| 12 | A Modified max-log-MAP Decoding Algorithm for Turbo Decoding显示文摘Turbo decoding is iterative decoding, and the MAP algorithm is optimal in terms of performance in Turbo decoding. The log MAP algorithm is the MAP executed in the logarithmic domain, so it is also optimal. Both the MAP and the log MAP algorithm are complicated for implementation. The max log MAP algorithm is derived from the log MAP with approximation, which is simply compared with the log MAP algorithm but is suboptimal in terms of performance. A modified max log MAP algorithm is presented in this paper, based on the Taylor series of logarithm and exponent. Analysis and simulation results show that the modified max log MAP algorithm outperforms the max log MAP algorithm with almost the same complexity. | ZOU Xue lan, FENG Guang zeng (Mobile Communication Lab, Nanjing University of Posts and Telecommunications,Nanjing 210003, P. R. China) | 2002 | The Journal of China Universities of Posts and Telecommunications2002，9，1： | 7 |
| 13 | Chemokine RANTES is upregulated in monocytes from patients with hyperhomocysteinemia显示文摘瞄准:在 chemokine RANTES 的血浆水平调查变化(在激活之上调整了,表示并且藏匿的正常 T 房间) 并且脂肪的多糖(LPS ) 的应答的海角与 hyperhomocysteinemia (HHcy ) 在病人从单核白血球导致了 RANTES 分泌物。方法:人半胱氨酸(Hcy ) 的血浆层次, folate,和 RANTES 在孤立的人的单核白血球与 HHcy 和 RANTES 的 mRNA 合成与正常 Hcy 层次和 40 个病人在 38 个控制病人被测量被核糖核酸酶保护试金决定。结果:RANTES 的血浆水平与控制相比在 HHcy 病人被提高(中部 5.3 对 3.5 ng/mL, | Wei SUN Guang WANG Zhen-min ZHANG Xiao-kun ZENG Xian WANG | 2005 | Acta Pharmacologica Sinica2005，26，11： | 7 |
| 14 | Abiogenic hydrocarbons in commercial gases from the Songliao Basin,China显示文摘This paper discusses the kinetic fractionation, composition and distribution characteristics of carbon and hydrogen isotopes for various alkane gases formed in different environments, by different mecha- nisms and from different sources in nature. It is demonstrated that the biodegradation or thermode- gradation of complex high-molecule sedimentary organic material can form microbial gas or thermogenic gas. The δ 13C1 value ranges from -110‰ to -50‰ for microbial gases but from -50‰ to -35‰ (even heavier) for thermogenic gases. Controlled by the kinetic isotope fractionation, both microbial and thermogenic gases have δ 13C and δ D values characterized by normal distribution, i.e. δ 13C1< δ 13C2< δ 13C3< δ 13C4 and δ DCH4< δ DC2H6< δ DC3H8<δ DC4H10, and by a positive correlation between the δ 13C and δ D values. Simple carbonbearing molecules (CH4, CO and CO2) can form abiogenic alkane gases via polymerization in the abiological chemical process in nature, with δ 13C1 heavier than -30‰. Moreover, controlled by the kinetic isotope fractionation, abiogenic alkane gases are characterized by a reverse distribution of δ 13C values and a normal trend of δ D values, namely δ 13C1> δ 13C2> δ 13C3> δ 13C4 and δ DCH4<δ DC2H6< δ DC3H8< δ DC4H10. The δ 13C values and δ D values are negatively correlated. Natural gases from 26 commercial gas wells distributed in the Xujiaweizi and Yingshan-Miaotaizi faulted depressions in the Songliao Basin, China, show δ13C1 values ranging from -30.5‰ to -16.7‰ with a very narrow δ D range between -203‰―-196‰. These gases are characterized by a reverse distribution of δ 13C values but a normal distribution of δ D values, and a negative correlation between their δ 13C and δ D values, indicating an abiological origin. The present study has revealed that abiogenic hydrocarbons not only exist in nature but also can make significant contribution to commercial gas reserviors. It is estimated that the reserve volume of alkane gases with abiogenic characteristics in these 26 gas wells in the Songliao Basin is over 500×108 m3. The prospecting practice in the Songliao Basin has demonstrated that abiogenic alkane gases are of a promising resource, and it provides an example for the investigation of and search for abiogenic commercial natural gases worldwide. | WANG XianBin GUO ZhanQian TUO JinCai GUO HongYan LI ZhenXi ZHUO ShengGuang JIANG HongLiang ZENG LongWei ZHANG MingJie WANG LianSheng LIU ChunXue YAN Hong LI LiWu ZHOU XiaoFeng WANG YongLi YANG Hui WANG Guang | 2009 | Science China Earth Sciences2009，52，2： | 6 |
| 15 | The Least Square Constant Modulus Algorithm for Blind Adaptive Multiuser Detection显示文摘In this paper, we apply the Least Square Constant Modulus Algorithm( LSCMA ) to the blind Multiuser Detection( MUD ). The algorithm is shown to be globally stable and convergent for any linearly independent set of input data and converge faster than the conventional Steepest Descent CMA(SDCMA ) and Linearly Constrained CMA(LCCMA ),but more complex. | LIU Sheng mei, XU Chang jiang, FENG Guang zeng (Nanjing University of Posts and Telecommunications, Nanjing 210003, P.R. China) | 2001 | The Journal of China Universities of Posts and Telecommunications2001，8，4： | 5 |
| 16 | Micronuclei and cell survival in human liver cancer cells irradiated by 25MeV/u^(40)Ar^(14+)显示文摘INTRODUCTIONHeavyionswithhighlinearenergytransfer(LET)havethefolowingadvantagesascomparedwiththeconventionalXraysandγraysth... | LI Wen Jian 1, GAO Qing Xiang 2, ZHOU Guang Ming 1 and WEI Zeng Quan 1 | 1999 | World Journal of Gastroenterology1999，5，4： | 5 |
| 17 | Occurrences and Formation Mechanisms of Botryoidai Structures from the Sinian Dengying Formation,Sichuan Basin,China显示文摘Objective This study aims to characterize the occurrences and interior structural features of botryoidal structures from the Sinian Dengying Formation in the Sichuan Basin of Southwestern China,and to shed light on their formation mechanism.Method Based on the observation of outcrop and drilling cores,this study carried out polarizing microscope analyses and cathodoluminescence microscope analyses with respect to the botryoidal structures. | LIAN Chengbo QU Fang TAN Xiucheng LI Ling JIN Mindong ZENG Wei REN Quanxiong HU Guang LIU Hong | 2016 | Acta Geologica Sinica(English Edition)2016，90，1： | 5 |
| 18 | A New Method for Blood NT-proBNP Determination Based on a Near-infrared Point of Care Testing Device with High Sensitivity and Wide Scope显示文摘Objective To develop a rapid, highly sensitive, and quantitative method for the detection of NT-proBNP levels based on a near-infrared point-of-care diagnostic(POCT) device with wide scope. Methods The lateral flow assay(LFA) strip of NT-proBNP was first prepared to achieve rapid detection. Then, the antibody pairs for NT-proBNP were screened and labeled with the near-infrared fluorescent dye Dylight-800. The capture antibody was fixed on a nitrocellulose membrane by a scribing device. Serial dilutions of serum samples were prepared using NT-proBNP-free serum series. The prepared test strips, combined with a near-infrared POCT device, were validated by known concentrations of clinical samples. The POCT device gave the output of the ratio of the intensity of the fluorescence signal of the detection line to that of the quality control line. The relationship between the ratio value and the concentration of the specimen was plotted as a work curve. The results of 62 clinical specimens obtained from our method were compared in parallel with those obtained from the Roche E411 kit. Results Based on the log-log plot, the new method demonstrated that there was a good linear relationship between the ratio value and NT-proBNP concentrations ranging from 20 pg/mL to 10 ng/mL. The results of the 62 clinical specimens measured by our method showed a good linear correlation with those measured by the Roche E411 kit. Conclusion The new LFA detection method of NT-proBNP levels based on the near-infrared POCT device was rapid and highly sensitive with wide scope and was thus suitable for rapid and early clinical diagnosis of cardiac impairment. | ZHANG Xiao Guang SHU Yao Gen GAO Ju WANG Xuan LIU Li Peng WANG Meng CAO Yu Xi ZENG Yi | 2017 | Biomedical and Environmental Sciences2017，30，6： | 4 |
| 19 | Effect of Thermal Cycling on Properties and Microstructure of SnAgCuCe Soldered Joints in QFP Devices显示文摘Increasing global concern about the environment is bringing regulatory (European directives) and consumer ('green products') pressure on the electronics industry in Europe and Japan to reduce or completely eliminate the use of lead (Pb) in products. Among all lead-free solder alloys, SnAgCu solder system, which has better thermo-mechanical properties compared with those of SnPb solder, is proven to be one of the promising candidates for electronic assembly. Previous work also revealed that adding a small amount of rare earth Ce into SnAgCu solder can visibly improve the properties and inhibit the excessive growth of the intermetallic compound layer. Thermal fatigue properties of SnAgCuCe soldered joints in QFP devices under thermal conditions have been investigated by finite element method and experiments. Based on creep model of low stress and high stress, corresponding creep subroutine was established for simulating the stress and strain response of SnAgCuCe soldered joint from -55 ℃ to 125 ℃, and fatigue life was calculated using creep fatigue life prediction equation. Moreover, thermal cycling experiments were conducted, the experimental results were found to be close to the simulated results. In addition, the tensile force of SnAgCuCe soldered joints decreased with increasing number of thermal cycles, and the fracture mechanism transformed from toughness fracture to brittle intergranular fracture. Moreover the tensile force changes and fracture microstructure evolution could benefit the quantitative evaluations of the mechanical performances of lead-free soldered joints under thermal cycling loadings. | ZHANG Liang XUE Songbai GAO Lili ZENG Guang YU Shenglin SHENG Zhong | 2011 | Chinese Journal of Mechanical Engineering2011，24，4： | 4 |
| 20 | Time-division phase modulated single-photon interference in a Sagnac interferometer显示文摘We introduce a stable, long-distance single- photon Sagnac interferometer, which has a balanced con-figuration to efficiently compensate phase drift caused by change of the fiber-optic path. By using time-division phase modulation, single-photon interference was realized at 1550 nm in a 5-km-long as well as 27-km-long Sagnac fiber loops, with a fringe visibility higher than 90% and long-term sta-bility. The stable performance of the single-photon interfer-ence indicated that the time-division phase-modulated Sag- nac interferometer might readily lead to practical applica-tions in single-photon routing and quantum cryptography. | WU Guang, ZHOU Chunyuan & ZENG Heping Key Laboratory of Optical and Magnetic Resonance Spectroscopy and Department of Physics, East China Normal University, Shanghai 200062, China Correspondence should be addressed to Zeng Heping (e-mail: hpzeng @phy.ecnu.edu.cn) | 2003 | Chinese Science Bulletin2003，48，16： | 4 |
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