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| 1 | Quick ice mass loss and abrupt retreat of the maritime glaciers in the Kangri Karpo Mountains, southeast Tibetan Plateau显示文摘The maritime glaciers are sensitive to climate change because of high annual precipitation and high air temperature in the region. A combined comprehensive study was carried out based on glacier mass balance observation, GPS-based glacier terminus position survey, glacier Ground Penetrating Radar, topography maps and RS satellite images in the Kangri Karpo Mountains, Southeast Tibet. The study revealed a strong ice mass loss and quick glacier retreat since the 1970s. Ata Glacier, one glacier from the south slope of the Kangri Karpo Mountains, has formed a 6-km-long terminal moraine zone at the end of the glacier since the 1970s, and the accelerating retreat is largely due to the strong glacier sur- face melting. Mass balance study on the other four glaciers on the northern side of the Kangri Karpo Mountains shows that they are in large negative mass balance and the glaciers had retreated 15―19 m from May 2006 to May 2007. The in-situ glacier observation also shows that the glacier retreat is more obvious in small glaciers. The enhanced ice mass deficit caused by climate warming and the ongoing extinction of many small glaciers in this region could seriously affect the water resources, environ- ments, local climate and regional sustainable development in the near future. | YANG Wei YAO TanDong XU BaiQing WU GuangJian MA LingLong XIN XiaoDong | 2008 | Chinese Science Bulletin2008，53，16： | 11 |
| 2 | Serological Evidence of Bat SARS-Related Coronavirus Infection in Humans,China显示文摘Dear Editor,Severe acute respiratory syndrome coronavirus(SARSCo V)is the causative agent of the 2002–2003 SARS pandemic,which resulted in more than 8000 human infections worldwide and an approximately 10%fatality rate(Ksiazek et al.2003;Peiris et al.2004).The virus infects both upper airway and alveolar epithelial cells,resulting in mild to severe lung injury in | Ning Wang Shi-Yue Li Xing-Lou Yang Hui-Min Huang Yu-Ji Zhang Hua Guo ,Chu-Ming Luo Maureen Miller Guangjian Zhu Aleksei A. Chmura Emily Hagan Ji-Hua Zhou Yun-Zhi Zhang Lin-Fa Wang Peter Daszak Zheng-Li Shi | 2018 | Virologica Sinica2018，33，1： | 8 |
| 3 | Sequential therapy according to distinct disease progression patterns in advanced ALK-positive non-small-cell lung cancer after crizotinib treatment显示文摘Objective: Crizotinib is recommended as the first-line therapy for advanced anaplastic lymphoma kinase(ALK)-positive non-small-cell lung cancer(NSCLC). Despite its initial efficacy, patients ultimately acquire resistance to crizotinib within 1 year. In such patients, the optimal sequential therapy after crizotinib treatment remains unknown. This study explored which sequential therapy option confers the greatest benefit.Methods: A total of 138 patients with advanced ALK-positive NSCLC resistant to crizotinib were studied. Based on patterns of disease progression of metastases, patients were divided into 3 groups: brain progression, non-liver progression, and liver progression. Sequential therapies included crizotinib continuation plus local therapy, nextgeneration ALK inhibitors(ALKi's), and chemotherapy. The primary endpoint was overall survival(OS) from the time of crizotinib resistance to death or last follow-up.Results: The 138 patients included 64 cases with progression in brain, 57 cases in non-liver sites and 17 cases in liver. A significant difference in OS was observed among the distinct progression pattern(median OS, 25.4 months in brain, 15.8 months in non-liver, and 10.8 months in liver, respectively, P=0.020). The difference in OS among sequential therapies was statistically significant in the non-liver progression group(median OS, 27.6 months with next-generation ALKi's, 13.3 months with crizotinib continuation, and 10.8 months with chemotherapy,respectively, P=0.019). However, crizotinib continuation plus local therapy seems to provide non-inferior median OS compared with next-generation ALKi's for patients with brain progression(median OS, 28.9 months vs.32.8 months, P=0.204). And no significant differences in OS were found in patients with progression in liver(P=0.061).Conclusions: Crizotinib continuation together with local therapy might be a feasible strategy for patients with progression in brain beyond crizotinib resistance, as well as next-generation ALKi's. Next-generation ALKi's tended to provide a survival benefit in patients with non-liver progression. | Haiyan Xu Di Ma Guangjian Yang Junling Li Xuezhi Hao Puyuan Xing Lu Yang Fei Xu Yan Wang | 2019 | Chinese Journal of Cancer Research2019，31，2： | 6 |
| 4 | Recent high-resolution glaciochemical record from a Dasuopu firn core of middle Himalayas显示文摘A 16.8 m firn core of middle Himalayas was recovered on the col of Dasuopu glacier in August 2006,being 7000 m above sea level.A total of 317 samples were measured for stable oxygen isotope ratios(δ18O)and major ion concentrations(Na+,NH4+,K+,Mg2+,Ca2+,Cl?,SO42?,and NO3?).The firn core dating and seasonal partitioning were carried out based on the marked seasonal variations along the stable oxygen isotopes and crustal species(Ca2+,Mg2+)profiles.The multi-parameters and high-resolution glaciochemical data set of Dasuopu firn core recorded the detailed chemical characteristics of pre-cipitation in high-elevation region,middle Himalayas,since 1991 A.D.,which mainly originated from the crustal and anthropogenic sources,while the sea-salt contribution was minor.The seasonal variability of major ion concentrations was dominated by the seasonal alternation of the prevalent air mass,at-mospheric circulation situation and precipitation regime.Linear regression analysis indicated that most of the variance in annual ionic fluxes can be explained by a linear dependence on snow accumu-lation rate. | WANG PengLing YAO TanDong TIAN LiDe WU GuangJian LI Zhen YANG Wei | 2008 | Chinese Science Bulletin2008，53，3： | 4 |
| 5 | The Rheological Property and Foam Morphology of Linear Polypropylene and Long Chain Branching Polypropylene显示文摘The rheological behavior, thermal properties and foam morphology of linear polypropylene and long chain branching polypropylene prepared through UV irradiation reactive extrusion were studied by rheological test, melt index test, DSC and supercritical carbon dioxide foaming technology. Rheological test and melt index test confirmed that under UV irradiation and extrusion, adding photo-initiator and cross-linking agent could achieve the purpose of branching, thus improved the melt strength of polypropylene effectively. The DSC results revealed that with the introducing of long chain branching, the melting range of the polypropylene broadened and the crystallization temperature increased. Owing to the introduction of long chain branches, polypropylene exhibited higher melt strength and strain hardening behavior. Compared with linear polypropylene, the foam morphologies of long chain branching polypropylene were more uniform. | 黄锦涛 HE Guangjian 廖霞 HUANG Yajiang YANG Qi | 2013 | Journal of Wuhan University of Technology(Materials Science)2013，28，4： | 3 |
| 6 | Industrial-Scale Polypropylene–Polyethylene Physical Alloying Toward Recycling显示文摘Polypropylene(PP)and polyethylene(PE)play central roles in our daily life.However,their immiscibility presents a major hurdle in both industry and academia when recycling them into alloys with favorable mechanical properties.Moreover,typical compatibilizer-enabled approaches are limited due to increased environmental concerns.Herein,inspired by a traditional Chinese technique,we report a facile,industry-scale methodology that produces a PP/PE binary blend with a highly ordered honeycomb nanostructure without any additives.Due to its nanostructure,the blend exhibits enhanced tensile properties in com-parison with the parent components or with a sample prepared using an internal mixer.This approach has potential for applications not only in immiscible polymer blending,but also in non-sorting,compatibilizer-free waste plastics recycling.Through this technique,we expect that an environmentally friendly and sustainable plastic wastes recycling avenue can be found,and great economic benefits can be gained. | Jinping Qu Zhaoxia Huang Zhitao Yang Guizhen Zhang Xiaochun Yin Yanhong Feng Hezhi He Gang Jin Ting Wu Guangjian He Xianwu Cao | 2022 | Engineering2022，8，2： | 2 |
| 7 | Single-atom catalysts for metal-sulfur batteries:Current progress and future perspectives显示文摘Metal-sulfur batteries are recognized as a promising candidate for next generation electrochemical energy storage systems owing to their high theoretical energy density,low cost and environmental friendliness.However,sluggish redox kinetics of sulfur species and the shuttle effect lead to large polarization and severe capacity decay.Numerous approaches from physical barrier,chemical adsorption strategies to electrocatalysts have been tried to solve these issues and pushed the rate and cycle performance of sulfur electrodes to higher levels.Most recently,single-atom catalysts(SACs)with high catalytic efficiency have been introduced into metal-sulfur systems to achieve fast redox kinetics of sulfur conversion.In this review,we systematically summarize the current progress on SACs for sulfur electrodes from aspects of synthesis,characterization and electrochemical performance.Challenges and potential solutions for designing SACs for high-performance sulfur electrodes are discussed. | Ru Xiao Ke Chen Xiaoyin Zhang Zhenzhen Yang Guangjian Hu Zhenhua Sun Hui-Ming Cheng Feng Li | 2021 | Journal of Energy Chemistry2021，30，3： | 2 |
| 8 | One century sedimentary records of polycyclic aromatic hydrocarbons, mercury and trace elements in the Qinghai Lake, Tibetan Plateau显示文摘 | Xiaoping Wang Handong Yang Ping Gong Xin Zhao Guangjian Wu Simon Turner Tandong Yao | 2010 | Environmental Pollution2010，，10： | 1 |
| 9 | Microwave- assisted synthesis and characterization of hierarchically structured calcium fluoride 显示文摘 | Zhenxing Yang Guangjian Wang Yajie Guo | 2012 | Materials Research Bulletin2012，47，12： | 1 |
| 10 | Motor network reorganization in stroke patients with dyskinesias during a shoulder-touching task:A fNIRS study显示文摘Hemiplegia after stroke has become a major cause of the world's high disabilities,and it is vital to enhance our understanding of post-stroke neuroplasticity to develop e±cient rehabilitation programs.This study aimed to explore the brain activation and network reorganization of the motor cortex(MC)with functional near-infrared spectroscopy(fNIRS).The MC hemodynamic signals were gained from 22 stroke patients and 14 healthy subjects during a shoulder-touching task with the right hand.The MC activation pattern and network attributes analyzed with the graph theory were compared between the two groups.The results revealed that healthy controls presented dominant activation in the left MC while stroke patients exhibited dominant activation in the bilateral hemispheres MC.The MC networks for the two groups had small-world properties.Compared with healthy controls,patients had higher transitivity and lower global e±ciency(GE),mean connectivity,and long connections(LCs)in the left MC.In addition,both MC activation and network attributes were correlated with patient's upper limb motor function.The results showed the stronger compensation of the unaffected motor area,the better recovery of the upper limb motor function for patients.Moreover,the MC network possessed high clustering and relatively sparse inter-regional connections during recovery for patients.Our results promote the understanding of MC reorganization during recovery and indicate that MC activation and network could provide clinical assessment signi¯cance in stroke patients.Given the advantages of fNIRS,it shows great application potential in the assessment and rehabilitation of motor function after stroke. | Yizheng Zhang Dan Wang Dongyang Wang Kecheng Yan Li Yi Shuoshu Lin Guangjian Shao Zhiyong Shao Jinyan Sun Aoran Yang | 2023 | Journal of Innovative Optical Health Sciences2023，16，6： | 1 |
| 11 | Research and Application on Spark Clustering Algorithm in Campus Big Data Analysis显示文摘Big data analysis has penetrated into all fields of society and has brought about profound changes.However,there is relatively little research on big data supporting student management regarding college and university’s big data.Taking the student card information as the research sample,using spark big data mining technology and K-Means clustering algorithm,taking scholarship evaluation as an example,the big data is analyzed.Data includes analysis of students’daily behavior from multiple dimensions,and it can prevent the unreasonable scholarship evaluation caused by unfair factors such as plagiarism,votes of teachers and students,etc.At the same time,students’absenteeism,physical health and psychological status in advance can be predicted,which makes student management work more active,accurate and effective. | Qing Hou Guangjian Wang Xiaozheng Wang Jiaxi Xu Yang Xin | 2020 | Journal of Computer Science Research2020，2，1： | 0 |
| 12 | Terahertz Wireless Communications显示文摘With Wireless communications in the 0.1-10TeraHertz(THz)band are envisioned as one of the key enablers towards ubiquitous wireless communications beyond 5G accommodating a massive number of connected devices and ultra-high user data rates in the order of Tera-bit-per-second.The THz band is located between the millimeter-wave(mmWave)and the far infrared(IR)band and still considered as one of the least investigated and exploited regions in the electromagnetic spectrum. | Zhi Chen Chong Han Xianbin Yu Guangjian Wang Nan Yang Mugen Peng | 2021 | China Communications2021，18，5： | 0 |
| 13 | Expert recommendations on data collection and annotation of two dimensional ultrasound images in azoospermic males for evaluation of testicular spermatogenic function in intelligent medicine显示文摘Testicular two-dimensional ultrasound is a testing modality that is often used to evaluate azoospermia and other related diseases.With the continuous development of deep learning in recent years,the combination of deep learning and testicular ultrasound appears unstoppable despite a lack of relevant standards.One of the major problems associated with the digitization of ultrasound images is the uneven quality of data however,and a standardized data source and acquisition process has not yet been developed.Such a standard could fill the current gap,and establish acquisition criteria for ultrasound images of testes during the male reproductive period,including grayscale ultrasound,shear wave elastography,and contrast-enhanced ultrasound.By following these guidelines the quality of testicular ultrasound images would be improved and standardized,which would lay a solid foundation for the standardization of testicular ultrasound images,and assist automated evaluation of testicular spermatogenic function of whole testis in azoospermic males. | Wanling Huang Yifan Xiang Yahan Yang Qing Tang Guangjian Liu Hong Yang Erjiao Xu Huitong Lin Zhixing Zhang Zhe Ma Zhendong Li Ruiyang Li Anqi Yan Haotian Lin Zhu Wang Chinese Association of Artificial Intelligence Medical Artificial Intelligence Branch of the Guangdong Medical Association | 2022 | Intelligent Medicine2022，2，2： | 0 |
| 14 | Effect of annealing temperature on structure and electrochemical properties of LiCoO_2 cathode thin films显示文摘LiCoO2 thin films, which can be used as a cathode material in microbatteries, were deposited using radio frequency (r.f.) magnetron sputtering system from a LiCoO2 target and in an O2+Ar atmosphere. The films were characterized by various methods such as XRD, SEM and AFM. The LiCoO2 films were annealed in air at 300, 500, 700 and 800 ℃ respectively. The effect of the annealing temperature on the structure, the surface morphology and the electrochemical properties of the films were investigated. The LiCoO2 thin film deposited at room temperature is amorphous and has smaller grain size. With increasing of annealing temperature, the crystallinity of the films is promoted. When the annealing temperature increases to 700 ℃, the films have a perfect crystalline LiCoO2 phase. The LiCoO2 thin film without annealing has no discharge plateau and small discharge capacity (about 27 μAh·cm-2μm). The discharge capacity increases with the increasing of annealing temperature and reaches 47 μAh·cm-2μm for the film annealed with 700 ℃, which also shows the typical discharge plateau of 3.9 V. The cycle performance of LiCoO2 thin films of as grown and annealed at different temperatures were studied. In the case of the film without thermal treatment, the capacity fading is much faster than that of the film annealed at different temperature, showing about 40% capacity loss only after 25 cycles. However, in the case of the film annealed at 700 ℃, the capacity reaches to steady state gradually and maintained constantly with cycling. After 25 times cycling, the discharge capacity of the film annealed at 700 ℃ decreases to about 36.9 μAh·cm-2·μm, only 0.8% capacity loss per cycle. | YANG Zhimin XING Guangjian YANG Jian MAO Changhui DU Jun | 2006 | Rare Metals2006，25，z2： | 0 |
| 15 | Synthesis of Bio-based Epoxy Containing Phosphine Oxide as a Reactive Additive Toward Highly Toughened and Fire-retarded Epoxy Resins显示文摘The integration of high mechanical toughness,impact strength as well as excellent flame-retardant properties toward epoxy resins(EPs)have always been a dilemma.The inadequate overall performance of EPs severely restricts their sustainable utilization in engineering aspects over long-term.Herein,a new bio-based agent(diglycidyl ether of magnolol phosphine oxide,referred as DGEMP)derived from magnolol(classified as lignan),extracted from natural plants Magnolia officinalis,was successfully synthesized and further employed as a flameretardant reactive additive to diglycidyl ether of bisphenol A(DGEBA).As demonstration,the composite resin,DGEBA/15DGEMP(15 wt%DGEMP),achieved an Underwriters Laboratories-94 V-0 rating with a high limiting oxygen index(LOI)value(41.5%).In cone calorimeter tests,it showed that heat release and smoke production were effectively inhibited during combustion,wherein the peak heat release rate(PHRR)value of DGEBA/15DGEMP was reduced by 50%compared to neat DGEBA.Additionally,it exhibited a superior tensile strength(82.8 MPa),toughness(5.11MJ/m^(3))and impact strength(36.5 k J/m^(2)),much higher than that of neat DGEBA(49.7 MPa,2.05 MJ/m^(3)and 20.9 k J/m^(2)).Thus,it is highly anticipated that DGEMP imparts significantly improved mechanical and fire-retarded properties to conventional EPs,which holds a great potential to address the pressing challenges in EP thermosets industry. | Chunxiang Wei Tianyu Gao Yu Xu Wenjie Yang Guangjian Dai Ruiting Li SanE Zhu Richard K.K.Yuen Wei Yang Hongdian Lu | 2023 | Chinese Journal of Polymer Science2023，41，11： | 0 |
| 16 | Exploring the spatiotemporal relationship between green infrastructure and urban heat island under multi‐source remote sensing imagery:A case study of Fuzhou City显示文摘Green Infrastructure(GI)has garnered increasing attention from various regions due to its potential to mitigate urban heat island(UHI),which has been exacerbated by global climate change.This study focuses on the central area of Fuzhou city,one of the“furnace”cities,and aims to explore the correlation between the GI pattern and land surface temperature(LST)in the spring and autumn seasons.The research adopts a multiscale approach,starting from the urban scale and using urban geographic spatial characteristics,multispectral remote sensing data,and morphological spatial pattern analysis(MSPA).Significant MSPA elements were tested and combined with LST to conduct a geographic weighted regression(GWR)experiment.The findings reveal that the UHI in the central area of Fuzhou city has a spatial characteristic of“high temperature in the middle and low temperature around,”which is coupled with a“central scattered and peripheral concentrated”distribution of GI.This suggests that remote sensing data can effectively be utilised for UHI inversion.Additionally,the study finds that the complexity of GI,whether from the perspective of the overall GI pattern or the classification study based on the proportion of the core area,has an impact on the alleviation of UHI in both seasons.In conclusion,this study underscores the importance of a reasonable layout of urban green infrastructure for mitigating UHI. | Tingting Hong Xiaohui Huang Guangjian Chen Yiwei Yang Lijia Chen | 2023 | CAAI Transactions on Intelligence Technology2023，8，4： | 0 |
| 17 | Advances in research on neuromyelitis optica spectrum disorders and its clinical heterogeneity显示文摘Neuromyelitis optica spectrum disorders(NMOSD)is a demyelinating disease mainly involving the optic nerve and spinal cord.It has recurrent and aggravating attacks and high disability rate.Most patients have a stepwise progression,resulting in complete blindness or paraplegia.NMOSD lesions contain not only the optic nerve and spinal cord,but also other neurological and non-neurological symptoms,which has clinical heterogeneity.The discovery of aquaporin-4-immunoglobulin G(AQP4-IgG)attributed it to autoimmune ion-channel disease,and rituximab(RTX)has achieved good clinical efficacy in the treatment of NMOSD.Myelin oligodendrocyte glycoprotein(MOG)antibodies have been found in some AQP4-IgG-negative NMOSD patients,which have different clinical and immunological features,posing new challenges to the diagnosis and treatment of NMOSD,which may require re-design and testing of new immune-targeted drugs. | Yi Bao Ming Jin Qi Zhao Lu Liu Yanpeng Sun Xiaoqin Peng Lu Yang Guangjian Liu | 2019 | Journal of Translational Neuroscience2019，4，4： | 0 |
| 18 | Clinical features of intracranial metastasis of primary hepatocellular carcinoma with burst diplopia as the first manifestation:a case report显示文摘Intracranial metastasis of liver cancer is rare,and diplopia as the first manifestation is even more rare.This article aims to introduce a patient with sudden diplopia in a middle-aged man.Physical examination revealed left abductor nerve palsy,craniocerebral magnetic resonance imaging(MRI)showed intracranial metastatic tumor,and positron emission tomography-computer tomography(PET-CT)tracing of the original lesion detected the primary liver cancer.This paper provides clinical data for intracranial metastasis of primary liver cancer and the possible pathogenesis and mechanism of sudden diplopia. | Lu Yang Guangjian Liu Jun Xuan Huihui Wu Yujie Yan Yi Bao | 2019 | Journal of Translational Neuroscience2019，4，4： | 0 |
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