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7728篇 您的检索式:作者名="Guo Q"
    题名 作者 年代 出处 被引量
1Vascular endothelial growth factor receptor 2(VEGFR-2) plays a key role in vasculogenic mimicry formation,neovascularization and tumor initiation by Glioma stem-like cells显示文摘Human glioblastomas(GBM)are thought to be initiated by glioma stem-like cells(GSLCs).GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells.Here,we report a critical role of GSLCs in the formation of vasculogenic mimicry(VM),which defines channels lined by tumor cells to supply nutrients to early growing tumors andYao X Ping Y Liu Y Chen K Yoshimura T Liu M Gong W Chen C Niu Q Guo D Zhang X Wang JM Bian X 2013中国神经肿瘤杂志2013,11,3:23
2Association of N-terminal pro-brain natriuretic peptide with the severity of coronary artery disease in patients with normal left ventricular ejection fraction显示文摘Wu NQ Guo YL Li XL Liu J Qing P Xu RX Zhu CG Jia Y J Liu G Dong Q Jiang LX Li J J Ma FL 2014Chinese Medical Journal2014,,4:23
3Altered neurogenesis and disrupted expression of synaptic proteins in prefrontal cortex of SHANK3-deficient non-human primate显示文摘Jiezhao Zheng Zhujun Li Rui Tian Youming Lu Xiangyu Guo Yong-hui Jiang Xiao-Jiang Li Yong Q Zhang 2017Cell Research2017,27,10:11
4Cyclosporin A impairs dendritic cell migration by regulating chemokine receptor expression and inhibiting cyclooxygenase-2 expression显示文摘Chen T Guo J Yang M Han C Zhang M Chen W Liu Q Wang J Cao X 2005第二军医大学学报2005,26,11:11
5bFGF and heparin but not laminin are necessary factors in the mediums that affect NSCs differentiation into cholinergic neurons显示文摘Ren W Guo Q Yang Y Chen F 2006中国生物学文摘2006,20,5:10
6代谢健康的肥胖和腹型肥胖与高血压风险增加相关显示文摘代谢健康型肥胖是指具有正常代谢特征的肥胖人群。研究者在中国农村地区队列研究(the rural Chinese cohort study)的成年人中,探究了代谢健康型肥胖与高血压风险的关系。这项前瞻性队列研究纳入中国成人9137名,在基线时(2007-2008年)无高血压、2型糖尿病或血脂异常,在2013-2014年进行随访。周卫(译) 袁源(审校) Zhao Y Qin P Sun HH Liu Y Liu D Zhou Q Guo C Li Q Tian G Wu X Hu D Sun X Zhang M 2020中华高血压杂志2020,28,9:7
7血清netrin-1增加与缺血性脑卒中预后改善相关显示文摘先前的实验研究表明,血清netrin-1与缺血性脑卒中进展相关。进一步了解缺血性脑卒中患者中netrin-1的变化可能为缺血性脑卒中的预后评估提供新的思路。该研究旨在探讨血清netrin-1与缺血性脑卒中预后的关系。研究人员测定3346例中国急性缺血性脑卒中抗高血压试验(China antihypertensive trial in acute ischemic stroke,CATIS)中缺血性脑卒中患者基线血清netrin-1水平,所有患者均在脑卒中发病后3个月进行随访。主要观察指标是脑卒中发病后3个月内死亡和严重残疾(改良Rankin 量表评分≥3)。刘莉 叶鹏 Guo D Zhu Z Zhong C Peng H Wang A Xu T Peng Y Xu T Chen CS Li Q Ju Z Geng D Chen J Zhang Y He J 2019中华高血压杂志2019,27,5:6
8Purified human bone marrow multipotent mesenchymal stem cells regenerate infarcted myocardium in experimental rats显示文摘Zhang S Jia Z Ge J Gong L Ma Y Li T Guo J Chen P Hu Q Zhang P Liu Y Li Z Ma K Li L Zhou C 2006中国生物学文摘2006,20,5:5
9Cyclic adenosine 3',5'-monophosphate induces differentiation of mouse embryonic stem cells into cardiomyocytes显示文摘Chen Y Shao JZ Xiang LX Guo J Zhou Q J Yao X Dai LC Lu YL 2006中国生物学文摘2006,20,7:5
10脂蛋白a水平与冠状动脉粥样硬化性心脏病患者复发事件的关系显示文摘脂蛋白a是否是冠状动脉粥样硬化性心脏病(冠心病)患者复发性心血管事件(recurrent cardiovascular events,RCVEs)的预测因子尚未确定。本研究旨在探讨脂蛋白a对一个真实世界、大规模首诊心血管事件(cardiovascular event,CVE)患者队列中RCVEs的潜在影响。方法:本实验为多中心的前瞻性研究,纳入经血管造影诊断的冠心病并经历首次CVE的患者7562例。入院时测量所有患者的脂蛋白a浓度.周卫(译) 叶鹏(校) Liu HH Cao YX Jin JL Zhang HW Hua Q Li YF Guo YL Zhu CG Wu NQ Gao Y Xu RX Hong LF 2020中华高血压杂志2020,28,5:5
11Expression analysis of a-smooth muscle actin and tenascin-C in the periodontal ligament under orthodontic loading or in vitro culture显示文摘α-smooth muscle actin(α-SMA) and tenascin-C are stress-induced phenotypic features of myofibroblasts. The expression levels of these two proteins closely correlate with the extracellular mechanical microenvironment. We investigated how the expression of α-SMA and tenascin-C was altered in the periodontal ligament(PDL) under orthodontic loading to indirectly reveal the intrinsic mechanical microenvironment in the PDL. In this study, we demonstrated the synergistic effects of transforming growth factor-β1(TGF-β1) and mechanical tensile or compressive stress on myofibroblast differentiation from human periodontal ligament cells(h PDLCs). The h PDLCs under higher tensile or compressive stress significantly increased their levels of α-SMA and tenascin-C compared with those under lower tensile or compressive stress. A similar trend was observed in the tension and compression areas of the PDL under continuous light or heavy orthodontic load in rats. During the time-course analysis of expression, we observed that an increase in α-SMA levels was matched by an increase in tenascin-C levels in the PDL under orthodontic load in vivo. The time-dependent variation of α-SMA and tenascin-C expression in the PDL may indicate the time-dependent variation of intrinsic stress under constant extrinsic loading.Hui Xu Ding Bai L-Bruno Ruest Jian Q Feng Yong-Wen Guo Ye Tian Yan Jing Yao He Xiang-Long Han 2015International Journal of Oral Science2015,7,4:5
12Effects of luteinizing hormone and androgen on the development of rat progenitor Leydig cells in vitro and in vivo显示文摘祖先 Leydig 房间从干细胞被导出。祖先 Leydig 房间的增长和区别显著地在发身期间贡献 Leydig 房间数字。然而,这些过程的规定仍然保持不清楚。现在的学习的目的是决定 luteinizing 荷尔蒙(LH ) 或雄激素是否贡献祖先 Leydig 房间的增长和区别。Fourteen-day-old 男 Sprague-Dawley 老鼠与 NalGlu 被对待 7 天,它是一个释放 gonadotropin 荷尔蒙对手,到在垂体并且这样减少 LH 的分泌物,在睾丸的雄激素。老鼠与 LH 或 7 α 被共同管理; -methyl-nortestosterone (MENT ) 是对由 5 α 的新陈代谢抵抗的雄激素, -reductase 1 在祖先 Leydig 房间,和 LH 或雄激素的随后的效果被测量。3 H-Thymidine 静脉内地也被注入老鼠在祖先 Leydig 房间学习 thymidine 加入。祖先 Leydig 房间被检验。NalGlu 管理由 83 % 减少了祖先 Leydig 房间增长;。另外, LH 或 MENT 处理恢复了 Leydig 房间 proliferative 能力到 73 %或 50 %控制,分别地。增长相关的基因的送信人 RNA 层次用即时 PCR 被测量。Igf1, Lifr, Pdgfra, Bcl2, Ccnd3 和 Pcna 的表示层次是由 MENT 的 upregulated,并且 Pdgfra, Ccnd3 和 Pcna 的那些是由 LH 的 upregulated。LH 和 MENT 在 vitro 刺激了祖先 Leydig 房间的区别。我们断定 LH 和 MENT 涉及调整祖先 Leydig 房间的发展。Jing-Jing Guo Xue Ma Claire Q F Wang Yu-Fei Ge Qing-Quan Lian Dianne O Hard Yu-Fei Zhang Qiang Dong Yun-Fei Xu Ren-Shan Ge 2013Asian Journal of Andrology2013,15,5:4
13Physiological levels of ATP negatively regulate proteasome function显示文摘由 ubiquitin-proteasome 系统的细胞内部的蛋白质降级是 ATP 依赖者,和最佳的 ATP 集中激活 proteasome 在 vitro 的功能是 ~ 100 渭 M。细胞内部的 ATP 层次在在这个范围以内的水平通常在低 millimolar 范围,而是 ATP 被显示在 vitro 禁止 proteasome peptidase 活动。这里,我们报导支持在生理的层次的细胞内部的 ATP 双向地调整的一个假设的新证据 26S proteasome 在房间的解朊的功能。首先,我们证实 ATP 在 vitro 在 26S proteasome 上施加了双向规定,与最佳的 ATP 集中(在 50 和 100 渭 M 之间) 刺激 proteasome 像糜蛋白酶的活动。第二,我们发现操作细胞内部的 ATP 层次也在有教养的房间在 proteasome 特定的蛋白质底层的层次导致了双向变化。最后,测量增加提高的细胞内部的 ATP,当减少的细胞内部的 ATP 稀释了导致房间死亡的 proteasome 抑制的能力时。这些数据强烈建议在生理的集中范围以内的内长的 ATP 能在 proteasome 活动施加否定影响,允许房间到很快,在应力下面的 ATP 减小上的 upregulate proteasome 活动调节。Hongbiao Huang Xiaoyan Zhang Shujue Li Ningning Liu Wen Elan Emily McDowell Ping Zhou Canguo Zhao Haiping Guo Change Zhang Changshan Yang Guangmei Wen Xiaoxian Dong Li Lu Ningfang Ma Weihua Dong Q Ping Dou Xuejun Wang Jinbao Liu 2010Cell Research2010,20,12:4
14Control of stress in highly doped polysilicon multi-layer diaphragm structure显示文摘Chen L Q Miao J M Guo L H 2001Surface and Coating Technology2001,141,:2
15Pointwise Estimates for Linear Combinations of Gamma Operators 显示文摘Qi Q L Guo S S 2002Southeast Asian Bulletin of Math2002,26,:2
16Influence of Eutrophication on the Distribution of Total Mercury and Methylmercury in Hydroelectric Reservoirs显示文摘Meng Bo Feng X B Chen C X Qiu G L Sommar J Guo Y N Liang P Wan Q 2010EN2010,,5:2
17Inheritance of Ear Tip-Barrenness Trait in Maize显示文摘这篇论文的目的是在玉米(Zea mays L.) 学习耳朵尖端不孕特点的继承模式。在玉米的耳朵尖端不孕特点能被分类进二种类型,尖端贫瘠并且 tip-barrenless。二个近交系, 1x01-3 (tip-barrenless 类型) , wx04-1 (尖端贫瘠的类型) ,和他们的 F1, F2, BC1, BC2 代在他们的耳朵尖端不孕类型上被分析。结果证明 F1 是尖端贫瘠的类型;尖端贫瘠的类型对 tip-barrenless 类型的比率跟随了 12.78:在 F1 分离群体的 1 比率和在 BC1 的 2.75:l 比率。χ 2 测试显示耳朵尖端不孕类型的特点跟随了 2 副本显性基因的一个继承模式。社会科学统计套装软体分析显示耳朵尖端不孕长度的特点具有反常分发。上面的结果意味着那:(1 ) 玉米耳朵尖端不孕类型的特点被 2 副本显性基因控制;尖端贫瘠的类型在 tip-barrenless 类型上是主导的;(2 ) 尖端不孕长度的特点是多基因控制,主要基因期望的量标识; 数量性状。MENG Zhao-dong ZHANG Fa-jun DING Zhao-hua SUN Q i WANG Li-ming GUO Qing-fa WANG Hong-gang 2007Agricultural Sciences in China2007,6,5:2
18A novel mutation of keratin 9 in epidermolytic palmoplantar keratoderma combined with knuckle pads显示文摘Lu Y Guo C Liu Q 2003Am J Med Genet2003,,3:2
19Effects of the phase-separated melt on crystallization behavior and morphology in short chain branched metallocene polyethylenes显示文摘Fu Q Chiu F C McCreight K W Guo M Tseng W W Cheng S Z Keating M Y Hsieh E T and DesLauriers P J 0,,:2
20Mg-Ca-Zn bulk metallic glasses with high strength and significant ductility显示文摘GU X SHIFLET G J GUO F Q POON S J 2005Journal of Materials Research2005,20,8:1
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