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7篇 您的检索式:作者名="H.Cho"
    题名 作者 年代 出处 被引量
1Large-scale active RFID system utilizing ZigBee networks显示文摘H.Cho J.Kim Y.Baek 0,,02:1
2The serum ferritin level is an important predictor of hemorrhagic transformation in acute ischaemic stroke显示文摘K.‐H.Choi M.‐S.Park J.‐T.Kim T.‐S.Nam S.‐M.Choi B.‐C.Kim M.‐K.Kim K.‐H.Cho 2012European Journal of Neurology2012,,4:1
3Cardiovascular autonomic dysfunction predicts acute ischaemic stroke in patients with Type?2 diabetes mellitus: a 7‐year follow‐up study显示文摘S. H.Ko K. H.Song S. A.Park S. R.Kim B. Y.Cha H. Y.Son K. W.Moon K. D.Yoo Y. M.Park J. H.Cho K. H.Yoon Y. B.Ahn 2008Diabetic Medicine2008,,10:1
4通过x射线cT扫描技术对西部花岗岩在单轴和三轴受力状况下三维观测显示文摘Kawakata H.Cho A.Kiyaa T等 19991999,313,3:1
5Recent advances towards single biomolecule level understanding of protein adsorption phenomena unique to nanoscale polymer surfaces with chemical variations显示文摘Protein adsorption onto polymer surfaces is a very complex and ubiquitous phenomenon whose integrated process impacts essential applications in our daily lives such as food packaging materials,health devices,diagnostic tools,and medical products.Increasingly,novel polymer materials with greater chemical intricacy and reduced dimensionality are used for various applications involving adsorbed proteins on their surfaces.Hence,the nature of protein-surface interactions to consider is becoming much more complicated than before.A large body of literature exists for protein adsorption.However,most of these investigations have focused on collectively measured,ensemble-averaged protein behaviors that occur on macroscale and chemically unvarying polymer surfaces instead of direct measurements at the single protein or sub-protein level.In addition,interrogations of protein-polymer adsorption boundaries in these studies were typically carried out by indirect methods,whose insights may not be suitably applied for explaining individual protein adsorption processes occurring onto nanostructured,chemically varying polymer surfaces.Therefore,an important gap in our knowledge still exists that needs to be systematically addressed via direct measurement means at the single protein and sub-protein level.Such efforts will require multifaceted experimental and theoretical approaches that can probe multilength scales of protein adsorption,while encompassing both single proteins and their collective ensemble behaviors at the length scale spanning from the nanoscopic all the way to the macroscopic scale.In this review,key research achievements in nanoscale protein adsorption to date will be summarized.Specifically,protein adsorption studies involving polymer surfaces with their defining feature dimensions and associated chemical partitions comparable to the size of individual proteins will be discussed in detail.In this regard,recent works bridging the crucial knowledge gap in protein adsorption will be highlighted.New findings of intriguing protein surface assembly behaviors and adsorption kinetics unique to nanoscale polymer templates will be covered.Single protein and sub-protein level approaches to reveal unique nanoscale protein-polymer surface interactions and protein surface assembly characteristics will be also emphasized.Potential advantages of these research endeavors in laying out fundamentally guided design principles for practical product development will then be discussed.Lastly,important research areas still needed to further narrow the knowledge gap in nanoscale protein adsorption will be identified.David H.Cho Tian Xie Johnson Truong Andrew C.Stoner Jong-in Hahm 2020Nano Research2020,13,5:1
6A lncRNA from an inflammatory bowel disease risk locus maintains intestinal host-commensal homeostasis显示文摘Inflammatory bowel diseases(IBD)are known to have complex,genetically influenced etiologies,involving dysfunctional interactions between the intestinal immune system and the microbiome.Here,we characterized how the RNA transcript from an IBD-associated long non-coding RNA locus(“CARINH-Colitis Associated IRF1 antisense Regulator of Intestinal Homeostasis”)protects against IBD.We show that CARINH and its neighboring gene coding for the transcription factor IRF1 together form a feedforward loop in host myeloid cells.The loop activation is sustained by microbial factors,and functions to maintain the intestinal host-commensal homeostasis via the induction of the anti-inflammatory factor IL-18BP and anti-microbial factors called guanylate-binding proteins(GBPs).Extending these mechanistic insights back to humans,we demonstrate that the function of the CARINH/IRF1 loop is conserved between mice and humans.Genetically,the T allele of rs2188962,the most probable causal variant of IBD within the CARINH locus from the human genetics study,impairs the inducible expression of the CARINH/IRF1 loop and thus increases genetic predisposition to IBD.Our study thus illustrates how an IBD-associated lncRNA maintains intestinal homeostasis and protects the host against colitis.Hongdi Ma Taidou Hu Wanyin Tao Jiyu Tong Zili Han Dietmar Herndler-Brandstetter Zheng Wei Ruize Liu Tingyue Zhou Qiuyuan Liu Xuemei Xu Kaiguang Zhang Rongbin Zhou Judy H.Cho Hua-Bing Li Hailiang Huang Richard A.Flavell Shu Zhu 2023Cell Research2023,33,5:0
7循环肿瘤细胞:新的肺癌相关肿瘤标志物显示文摘循环肿瘤细胞(circulating tumor cell,CTC)计数与乳腺癌、大肠癌和前列腺癌的无进展生存期(progression free survival,PFS)和总生存期(overall survival,os)不佳相关。在肺癌治疗过程中,需要大量可以监测患者疾病进展的多功能肿瘤生物标志物。研究[1-2]发现,肺癌的主要治疗方法——手术治疗,可引起CTC的增加。这有可能造成不同的残留病灶,即使是在全肿瘤切除的成功病例中也是如此。在有关肺癌的CTC研究中,Edward H.Cho 邢西迁 徐毅 2013国际病理科学与临床杂志2013,33,5:0
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