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| 1 | Regulation of mATG9 trafficking by Src- and ULK1mediated phosphorylation in basal and starvation-induced autophagy显示文摘Autophagy 要求多样的膜来源并且包含 mATG9 的膜 trafficking,在 ATG 家庭的唯一的膜蛋白质。然而,为 autophagy 开始的 mATG9 trafficking 的分子的规定仍然保持不清楚。这里,我们识别了在 mATG9 的 cytosolic N 终点以内排序信号的二保存经典适配器蛋白质,它调停从经由和 AP1/2 建筑群的相互作用的血浆膜和 trans-Golgi 网络(TGN ) 的 mATG9 的 trafficking。在 Tyr8 到的 Src phosphorylates mATG9 处于不着重的条件维持它的 endocytic 和组成的 trafficking。响应饥饿,在由 Src 的 Tyr8 并且在由 ULK1 的 Ser14 的 mATG9 的 phosphorylation 机能上地合作支持在 mATG9 和 AP1/2 建筑群之间的相互作用,为 autophagy 从血浆膜和 juxta 原子的区域导致 mATG9 的再分配到外部水池开始。我们的调查结果揭开 mATG9 trafficking 的新奇机制并且建议基础、导致压力的 autophagy 的协作。 | Changqian Zhou Kaili Ma Ruize Gao Chenglong Mu Linbo Chen Qiangqiang Liu Qian Luo Du Feng Yushan Zhu Quan Chen | 2017 | Cell Research2017，27，2： | 2 |
| 2 | An inhibitory role for FAK in regulating proliferation:a link between limited adhesion and RhoA-ROCK signaling显示文摘 | DM Pirone Liu WF Ruiz SA | | 0，，： | 1 |
| 3 | A point mutation in the cysteine-rich domain of glycoprotein (GP) IIIa results in the expression of a GPIIb-IIIa ( alphallbbeta3 ) integrin receptor locked in a high-affinity state and a Glanzmann thrombasthenia-like phenotype 显示文摘 | RUIZ C LIU CY SUN QH | 2001 | Blood2001，98，8： | 1 |
| 4 | Bandwidth-Efficient Geographic Multicast Routing Protocol for Wireless Sensor Networks显示文摘 | Senchez J A Ruiz P M Jennifer Liu | 2007 | IEEE Sensor Journal2007，7，5： | 1 |
| 5 | Constitutively-active Gq impairs gonadotropin-releasing hormone-induced intracellular signaling and LH secretion in Lβ T2 cells 显示文摘 | LIU FUJUN RUIZ M S AUSTIN D A | 2005 | Mol Endocrinol2005，19，8： | 1 |
| 6 | bandwidth-efficient geographic multicast routing protocol for wireless sensor networks显示文摘 | Sanchez J A Ruiz P M Liu Jennifer | 2007 | IEEE Sensor Journal2007，7，5： | 1 |
| 7 | Recapitulation of prematureaging with iPSCs from Hutchinson - Gilford progeria syndrome显示文摘 | Liu GH Barkho BZ Ruiz S | 2011 | Nature2011，472，7342： | 1 |
| 8 | Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome 显示文摘 | Liu GH Barkho BZ Ruiz S | 2011 | Nature2011，472，7342： | 1 |
| 9 | Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria sydrome 显示文摘 | Liu GH Barkho BZ Ruiz S | 2011 | Nature2011，472，7342： | 1 |
| 10 | An inhibitory role for FAK in regulating proliferation: a link between lim- ited adhesion and RhoA-ROCK signaling显示文摘 | Pirone DM Liu WF Ruiz SA | 2006 | J Cell Biol2006，174，2： | 1 |
| 11 | Bandwidth-Efficient Geographic Multicast Routing Protocol for Wireless Sensor Networks显示文摘 | Ruiz P M Liu Jennifer Ivan Stojmenovic | 2007 | Sensors Journal IEEE2007，，7： | 1 |
| 12 | Predicting AD conve- rsion: comparison between prodromal AD guidelines and computer assisted predictAD tool显示文摘 | LIU Y MATrILA J RUIZ MA | 2013 | Plos One2013，8，55： | 1 |
| 13 | Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome 显示文摘 | Liu GH Barkho BZ Ruiz S etal | 2011 | Nature2011，472，7342： | 1 |
| 14 | A point mutation in the cyste- ine-rich domain of glycoprotein (GP) l~a results in the expression of a GP 11 b-Ilia (a 1I b显示文摘 | Ruiz C Liu CY Sun QH | 2001 | Blood2001，98，8： | 1 |
| 15 | Bandwidth-Efficient Geographic Muhicast Routing Protocol for Wireless Sensor Networks 显示文摘 | JUAN A Sanchez PEDRO M Ruiz JENNIFER Liu | 2007 | IEEE Sensors Journal2007，7，5： | 1 |
| 16 | Bandwidth- Efficient Geographic Multicast Routing Protocol for Wireless Sensor Networks显示文摘 | SAMCHEZ J A RUIZ P M LIU J | 2007 | IEEE Sensors Journal2007，7，5： | 1 |
| 17 | Comparative thermal denaturation of Thermus aquaticus and Escherichia coli type 1 DNA polymerases 显示文摘 | Karantzeni I Ruiz C Liu C C | 2003 | Biochemical Journal2003，374，： | 1 |
| 18 | An Experimental Study on Oxidized Mercury Adsorption by Bromide Blended Coal Combustion Fly Ash显示文摘The application of forced mercury oxidation technology would lead to an increase of Hg^(2+)concentration in the flue gas.Although Hg^(2+)can be easily removed in the WFGD,the mercury re-emission in the WFGD can decrease the total removal of mercury from coal-fired power plants.Hence,it is necessary to control Hg^(2+)concentration in the devices before the WFGD.Fly ash adsorbent is considered as a potential alternative for commercial activated carbon adsorbent.However,the adsorption efficiency of the original fly ash is low.Modification procedure is needed to enhance the adsorption performance.In this study,the adsorption of Hg^(2+)by brominated fly ash was studied.The fly ash was collected from the full-scale power plant utilizing bromide-blended coal combustion technology.The brominated fly ash exhibited excellent performance for Hg^(2+)removal.The flue gas component HBr and SO_(2)could improve adsorbent’s performance,while HCl would hinder its adsorption process.Also,it was demonstrated by Hg-TPD experiments that the adsorbed Hg^(2+)mainly existed on the fly ash surface in the form of HgBr_(2).In summary,the brominated fly ash has a broad application prospect for mercury control. | Mingyu Yu Mengyuan Liu Guangqian Luo Ruize Sun Jingyuan Hu Hailu Zhu Li Zhong Lipeng Han Xian Li Hong Yao | 2021 | Energy Engineering2021，118，5： | 0 |
| 19 | Altered asymmetries of resting-state MRI in the left thalamus of first-episode schizophrenia显示文摘Background:Schizophrenia(SCZ)is a complex psychiatric disorder associated with widespread alterations in the subcortical brain structure.Hemispheric asymmetries are a fundamental organizational principle of the human brain and relate to human psychological and behavioral characteristics.We aimed to explore the state of thalamic lateralization of SCZ.Methods:We used voxel-based morphometry(VBM)analysis,whole-brain analysis of low-frequency fluctuations(ALFF),fractional amplitude of low-frequency fluctuations(fALFF),and resting-state seed-based functional connectivity(FC)analysis to investigate brain structural and functional deficits in SCZ.Also,we applied Pearson’’s correlation analysis to validate the correlation between Positive and Negative Symptom Scale(PANSS)scores and them.Results:Compared with healthy controls,SCZ showed increased gray matter volume(GMV)of the left thalamus(t=2.214,p=0.029),which positively correlated with general psychosis(r=0.423,p=0.010).SCZ also showed increased ALFF in the putamen,the caudate nucleus,the thalamus,fALFF in the nucleus accumbens(NAc),and the caudate nucleus,and decreased fALFF in the precuneus.The left thalamus showed significantly weaker resting-state FC with the amygdala and insula in SCZ.PANSS negative symptom scores were negatively correlated with the resting-state FC between the thalamus and the insula(r=-0.414,p=0.025).Conclusions:Collectively,these results suggest the possibility of aberrant laterality in the left thalamus and its FC with other related brain regions involved in the limbic system. | Sha Liu Zhenglong Guo Hongbao Cao Hong Li Xiaodong Hu Long Cheng Jianying Li Ruize Liu Yong Xu | 2022 | Chronic Diseases and Translational Medicine2022，8，3： | 0 |
| 20 | Novel concept of nano-additive design:PTFE@silica Janus nanoparticles for water lubrication显示文摘Polytetrafluoroethylene(PTFE)has been widely used as a lubrication additive for reducing friction and wear;however,the hydrophobic nature of PTFE restricts its application in eco-friendly water-based lubrication systems.In this study,for the first time,we designed novel PTFE@silica Janus nanoparticles(JNs)to meet the requirement for additives in water-based lubricants,which have excellent dispersion stability in water attributed to the unique amphiphilic structure.By introducing the lubrication of the aqueous dispersion of the JNs with a concentration of 0.5 wt%,the coefficient of friction(COF)and wear volume were reduced by 63.8%and 94.2%,respectively,comparing to those with the lubrication of pure water.Meanwhile,the JNs suspension also exhibits better lubrication and wear-resistance performances comparing to commercial silica and PTFE suspensions.The excellent tribological behaviors of PTFE@silica JNs as nano-additives could be attributed to the synergetic effect of the two components,where the PTFE provided lubrication through the formed tribofilms on the friction pairs,and the rigid silica further enhanced the wear-resistance performance.Most importantly,the unique structure of JNs makes it possible to use PTFE as an additive in water-lubrication systems.Our study shed light on the design and application of novel JNs nanomaterials as additives to meet the requirements of future industrial applications. | Yanfei LIU Hailing HE Meng YANG Ruize ZHANG Shengtao YU Tiantian YANG Wenzhong WANG Fuxin LIANG | 2024 | Friction2024，12，2： | 0 |
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