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| 1 | The Role of TNF Related Apoptosis-Inducing Ligand in Neurodegenerative Diseases显示文摘A hallmark of all forms of neurodegenerative diseases is impairment of neuronal functions, and in many cases neuronal cell death. Although the etiology of neurodegenerative diseases may be distinct, different diseases display a similar pathogenesis, for example abnormal immunity within the central nervous system (CNS), activation of macrophage/microglia and the involvement of proinflammatory cytokines. Recent studies show that neurons in a neurodegenerative state undergo a highly regulated programmed cell death, also called apoptosis. TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF family, has been shown to be involved in apoptosis during many diseases. As one member of a death ligand family, TRAIL was originally thought to target only tumor cells and was not present in CNS. However, recent data showed that TRAIL was unregulated in HIV-1-infected and immune-activated macrophages, a major disease inducing cell during HIV-1-associated dementia (HAD). TRAIL is also induced on neuron by β-amyloid protein, an important pathogen for Alzheimer's disease. In this review, we summarize the possible common aspects that TRAIL involved those neurodegenerative diseases, TRAIL induced apoptosis signaling in the CNS cells, and specific role of TRAIL in individual diseases. Cellular & Molecular Immunology. 2005;2(2):113-122. | Y.Huang N.Erdmann H.Peng Y.Zhao | 2005 | Cellular & Molecular Immunology2005,2,2: | 15 |
| 2 | Microstructure and mechanical properties of Mg-to-Al dissimilar welded joints with an Ag interlayer using ultrasonic spot welding显示文摘Lightweight ZEK100-0 Mg alloy and A16022-T43 Al alloy with an Ag interlayer were joined via ultrasonic spot welding(USW),focusing on the microstructural change and tensile lap shear strength of the welded joints in relation to welding energy.Mg/Al interface was superseded by Mg/Ag and Al/Ag interfaces,and unfavorable Mg门A-intermetallic compound was eliminated.Ag foil was observed to be intact in the nugget center,while it was broken or dissolved at the nugget edge at high welding energy levels.The diffusion layer at the Mg/Ag interface consisted of two distinctive sub-layers:Mg3Ag intermetallic compound adjoining Ag foil,and Mg3Ag-l-Mg eutectic structure adjacent to Mg.Only a thin diffusion layer consisting mainly of Ag3Al occurred al lhe Al/Ag interface.The tensile lap shear strength first increased,reached its peak value,and then decreased with increasing welding energy.The shear strength achieved in the present study was〜31%higher than that of the joint without interlayer.Interfacial failure occurred at all energy levels,with Ag foil particles or fragments being stuck on both Mg and Al sides due to its intense interaction with Mg and Al via accelerated diffusion during USW.The results obtained pave the way for the challenging dissimilar welding between Mg and Al alloys. | H.Peng D.L.Chen X.F.Bai P.Q.Wang D.Y.Li X.Q.Jiang | 2020 | Journal of Magnesium and Alloys2020,8,2: | 11 |
| 3 | High performance lithium battery anodes using silicon nanowires显示文摘 | C.K.Chan H.Peng G.Liu K.Mcilwrath X.F.Zhang R.A.Huggins Y.Cui | | 0,,01: | 1 |
| 4 | Inhibition of Matrix Metalloproteinase‐9 Attenuates Acute Small‐for‐Size Liver Graft Injury in Rats显示文摘 | Z. Y.Ma J. M.Qian X. H.Rui F. R.Wang Q. W.Wang Y. Y.Cui Z. H.Peng | 2010 | American Journal of Transplantation2010,,4: | 1 |
| 5 | Spinel LiMn2O4 nanorods as lithium ion battery cathodes显示文摘 | K.Kim P.Muralidharan H.-W.Lee R.Ruffo Y.Yang C.K.Chan H.Peng R.A.Huggins Y.Cui | | 0,,: | 1 |
| 6 | 查看详情显示文摘 | D.Kong W.Dang J.J.Cha H.Li S.Meister H.Peng Z.Liu and Y.Cui | | 0,,06: | 1 |
| 7 | Inhibition of Matrix Metalloproteinase‐9 Attenuates Acute Small‐for‐Size Liver Graft Injury in Rats显示文摘 | Z. Y.Ma J. M.Qian X. H.Rui F. R.Wang Q. W.Wang Y. Y.Cui Z. H.Peng | 2010 | American Journal of Transplantation2010,,4: | 1 |
| 8 | Plasma optics in the context of high intensity lasers显示文摘The use of plasmas provides a way to overcome the low damage threshold of classical solid-state based optical materials,which is the main limitation encountered in producing and manipulating intense and energetic laser pulses.Plasmas can directly amplify or alter the characteristics of ultra-short laser pulses via the three-wave coupling equations for parametric processes.The strong-coupling regime of Brillouin scattering(sc-SBS)is of particular interest:recent progress in this domain is presented here.This includes the role of the global phase in the spatio-temporal evolution of the three-wave coupled equations for backscattering that allows a description of the coupling dynamics and the various stages of amplification from the initial growth to the so-called self-similar regime.The understanding of the phase evolution allows control of the directionality of the energy transfer via the phase relation between the pulses.A scheme that exploits this coupling in order to use the plasma as a wave plate is also suggested. | H.Peng J.-R.Marques L.Lancia F.Amiranoff R.L.Berger S.Weber C.Riconda | 2019 | Matter and Radiation at Extremes2019,4,6: | 0 |