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| 1 | Finite Groups in Which all Nonlinear Irreducible Characters have Distinct Degrees 显示文摘 | Berkovich Y Chillag D Herzog M | 1992 | Proc Amer Math Soc1992，106，： | 2 |
| 2 | Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome:A multicenter retrospective study显示文摘BACKGROUND Single-nucleotide polymorphisms(SNPs)of the serotonin type 3 receptor subunit(HTR3)genes have been associated with psychosomatic symptoms,but it is not clear whether these associations exist in irritable bowel syndrome(IBS).AIM To assess the association of HTR3 polymorphisms with depressive,anxiety,and somatization symptoms in individuals with IBS.METHODS In this retrospective study,623 participants with IBS were recruited from five specialty centers in Germany,Sweden,the United States,the United Kingdom,and Ireland.Depressive,anxiety,and somatization symptoms and sociodemographic characteristics were collected.Four functional SNPs—HTR3A c.-42C>T,HTR3B c.386A>C,HTR3C c.489C>A,and HTR3E c.*76G>A—were genotyped and analyzed using the dominant and recessive models.We also performed separate analyses for sex and IBS subtypes.SNP scores were calculated as the number of minor alleles of the SNPs above.The impact of HTR3C c.489C>A was tested by radioligand-binding and calcium influx assays.RESULTS Depressive and anxiety symptoms significantly worsened with increasing numbers of minor HTR3C c.489C>A alleles in the dominant model(F_(depressive)=7.475,P_(depressive)=0.006;F_(anxiety)=6.535,P_(anxiety)=0.011).A higher SNP score(range 0-6)was linked to a worsened depressive symptoms score(F=7.710,P-linear trend=0.006)in IBS.The potential relevance of the HTR3C SNP was corroborated,showing changes in the expression level of 5-HT3AC variant receptors.CONCLUSION We have provided the first evidence that HTR3C c.489C>A is involved in depressive and anxiety symptoms in individuals with IBS.The SNP score indicated that an increasing number of minor alleles is linked to the worsening of depressive symptoms in IBS. | Sabrina Berens Yuanjun Dong Nikola Fritz Jutta Walstab Mauro D'Amato Tenghao Zheng Verena Wahl Felix Boekstegers Justo Lorenzo Bermejo Cristina Martinez Stefanie Schmitteckert Egbert Clevers Felicitas Engel Annika Gauss Wolfgang Herzog Robin Spiller Miriam Goebel-Stengel Hubert Mönnikes Viola Andresen Frieling Thomas Jutta Keller Christian Pehl Christoph Stein-Thöringer Gerard Clarke Timothy G Dinan Eamonn M Quigley Gregory Sayuk Magnus Simrén Jonas Tesarz Gudrun Rappold Lukas van Oudenhove Rainer Schaefert Beate Niesler | 2022 | World Journal of Gastroenterology2022，28，21： | 2 |
| 3 | The prevalence of cardiac valvular insufficiency assessed by transthoracic echocardiography in obese patients treated with appetite-suppressant drugs 显示文摘 | Khan M A Herzog C A Peter J V St | 1998 | N Engl J Med1998，339，11： | 1 |
| 4 | Machine and Component Residual Life Estimation Through the Application of Neural Networks显示文摘 | HERZOG M A MARWALA T HEYNS P S | 2009 | Reliability Engi- neering and System Safety2009，94，2： | 1 |
| 5 | Stretch and interleukin-1beta induce matrix metalloproteinases in rabbit tendon cells in vitro 显示文摘 | Archambault J Tsuzaki M Herzog W | 2002 | J Orthop Res2002，20，1： | 1 |
| 6 | Striatal delivery of neurturin by CERE-120, an AAV2 vector for the treatment of dopaminergic neuron degeneration in Parkinson's disease 显示文摘 | Gasmi M Herzog CD Brandon EP | 2007 | Mol Ther2007，15，1： | 1 |
| 7 | ADAMTS13 autoantibodies in patients with thrombotic microangiopathies and other immunomedi- ated diseases显示文摘 | Rieger M Mannucci PM Kremer Hovinga JA Herzog A Ger- stenbauer G Konetschny C | 2005 | Blood2005，106，4： | 1 |
| 8 | Brand- specific leadership : Turning employees into brand champions 显示文摘 | Morhart F M Herzog W Tomczak T | 2009 | Journal of Marketing2009，73，5： | 1 |
| 9 | Global 2-D intercomparison of sectional and modal aerosol modules 显示文摘 | Weisenstein D K Penner J E Herzog M | 2007 | Atmos Chem Phys2007，7，： | 1 |
| 10 | On finite simple groups of orders divided by three prime only 显示文摘 | Herzog M | 1968 | JAlgebra1968，10，： | 1 |
| 11 | Landscape Metrics for Assessment of Landscape Destruction and Rehabilitation显示文摘 | FELIX HERZOG ANGELA LAUSCH ECKHARD MüLLER HANS-HERMANN THULKE UTA STEINHARDT STEFFEN LEHMANN | | Environmental Management0，，： | 1 |
| 12 | Carbon dioxide recovery and dispos- al from large energy system 显示文摘 | HERZOG H J DRAKE E M | 1996 | Annual Review Energy Environ- ment1996，21，1： | 1 |
| 13 | Multi-detector row CT coronary angiography: influence of reconstruction technique and heart rate on image quality显示文摘 | Herzog C Arning-Erb M Zangos S | 2006 | Radiology2006，238，1： | 1 |
| 14 | Field evaluation of fourteen soybean genotypes for resistance to Whitefly( Homoptera: Aleyrodidae) infestations 显示文摘 | Lambert A L Mepherson R M Herzog G A | 1997 | Journal of Economic Entomology1997，90，2： | 1 |
| 15 | Cerebral microbleeds in CADASIL: a gradient-echo magnetic resonance imaging and autopsy study显示文摘 | Dichgans M Holtmannspotter M Herzog J | 2002 | Stroke2002，33，1： | 1 |
| 16 | Vis- ual system labeled by c-Fos immunohistochemistry af- ter light exposure in the 'blind' subterranean Zambi- an mole-rat (Cryptomys anselli)显示文摘 | Oelschlager H H Nakamura M Herzog M | 2000 | Brain Behav Evo l2000，55，4： | 1 |
| 17 | Determination of trace metals by underpotential deposition-stripping voltammetry at solid electrodes显示文摘 | Herzog G Arrigan D W M | 2005 | Trends Anal Chem2005，24，3： | 1 |
| 18 | Capacitance limits of high surface area activated carbons for double layer capacitors 显示文摘 | Barbieri O Hahn M Herzog A | 2005 | Carbon2005，43，6： | 1 |
| 19 | On Finite Simple Groups of Order Divisible by There Primes Only显示文摘 | HERZOG M | 1968 | J Algebra1968，10，： | 1 |
| 20 | Association of genotypes affecting the expression of interleukin-1beta or interleukin-1 receptor antagonist with osteoarthritis显示文摘 | Moos V Rudwaleit M Herzog V | 2000 | Arthritis Rheum2000，43，： | 1 |
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