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| 1 | Prolongation of life span of Stroke-prone spontaneously hypertensive rats (SHRSP) ingesting persimmon tarnin显示文摘 | Shinji U C Hisashi O Masami N | 1990 | Chem Pharm Bull1990，38，4： | 1 |
| 2 | Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors显示文摘 | Masaharu Akiyama Osamu Yamada Naotoshi Kanda Shinobu Akita Takeshi Kawano Tsuneya Ohno Hideaki Mizoguchi Yoshikatsu Eto Kenneth C Anderson Hisashi Yamada | 2002 | Cancer Letters2002，，2： | 1 |
| 3 | Alpha1, 3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months 显示文摘 | Tseng Y L Dor F J Shimizu A Houser S Hisashi Y Yamada K Robson S C Awwad M Schuurman H J Sachs D H Cooper D K | 2005 | Transplantation2005，80，11： | 1 |
| 4 | Effects on air pollutant removal by plant absorption and adsorption显示文摘 | Shuji F Hiun C Naoki K Hisashi M | 2005 | Building and Environment2005，40，1： | 1 |
| 5 | Co-channel interference mitigation detectors for multirate transmission in TD-CDMA systems 显示文摘 | Piero C Hisashi K | 2002 | IEEE J Select Areas Commune2002，20，： | 1 |
| 6 | Marked prolongation of porcine renal xenograft survival in baboons through the use of α-1, 3 galactosyltransferase gene-knock out donors and the cotransplantation of vascularized thymic tissue显示文摘 | Yamada K Yazawa K Shimizu A Iwanaga T Hisashi Y Nuhn M O'Malley P Nobori S Vagefi P A Patience C Fisherman J Cooper D K C Hawley R J Greenstein J Schuurman H-J Awwad M Sykes M Sachs D H | 2005 | Nature Medicine2005，11，1： | 1 |
| 7 | Ovarian development and final oocyte maturation in cultured sevenband grouper Epinephelus septemfasciatus 显示文摘 | NILAR S HISASHI C TOSHIHISA A | 2004 | Fisheries Science2004，70，3： | 1 |
| 8 | Performance of VOC abatement by thermal swing honeycomb rotor absorbers 显示文摘 | Hisashi Y C Akio K M Tsutomou H | 2007 | Industrial & Engineering Chemistry Research2007，46，12： | 1 |
| 9 | Ovarian development and final oocyte maturation in cultured sevenband grouper Epinephelus septemfasciatus 显示文摘 | NILAR S HISASHI C TOSHIHISA A | 2004 | Fisheries Science2004，70，3： | 1 |
| 10 | Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors显示文摘 | Masaharu Akiyama Osamu Yamada Naotoshi Kanda Shinobu Akita Takeshi Kawano Tsuneya Ohno Hideaki Mizoguchi Yoshikatsu Eto Kenneth C Anderson Hisashi Yamada | 2002 | Cancer Letters2002，，2： | 1 |
| 11 | Tomato expressing Arabidopsis glutaredoxin gene AtGRXS17 confers tolerance to chilling stress via modulating cold responsive components显示文摘Chilling stress is a production constraint of tomato,a tropical origin,chilling-sensitive horticultural crop.The development of chilling tolerant tomato thus has significant potential to impact tomato production.Glutaredoxins(GRXs)are ubiquitous oxidoreductases,which utilize the reducing power of glutathione to reduce disulfide bonds of substrate proteins and maintain cellular redox homeostasis.Here,we report that tomato expressing Arabidopsis GRX gene AtGRXS17 conferred tolerance to chilling stress without adverse effects on growth and development.AtGRXS17-expressing tomato plants displayed lower ion leakage,higher maximal photochemical efficiency of photosystem II(Fv/Fm)and increased accumulation of soluble sugar compared with wild-type plants after the chilling stress challenge.Furthermore,chilling tolerance was correlated with increased antioxidant enzyme activities and reduced H2O2 accumulation.At the same time,temporal expression patterns of the endogenous C-repeat/DRE-binding factor 1(SlCBF1)and CBF mediated-cold regulated genes were not altered in AtGRXS17-expressing plants when compared with wild-type plants,and proline concentrations remained unchanged relative to wild-type plants under chilling stress.Green fluorescent protein-AtGRXS17 fusion proteins,which were initially localized in the cytoplasm,migrated into the nucleus during chilling stress,reflecting a possible role of AtGRXS17 in nuclear signaling of chilling stress responses.Together,our findings demonstrate that genetically engineered tomato plants expressing AtGRXS17 can enhance chilling tolerance and suggest a genetic engineering strategy to improve chilling tolerance without yield penalty across different crop species. | Ying Hu Qingyu Wu Stuart A Sprague Jungeun Park Myungmin Oh C B Rajashekar Hisashi Koiwa Paul A Nakata Ninghui Cheng Kendal D Hirschi Frank F White Sunghun Park | 2015 | Horticulture Research2015，2，1： | 1 |
| 12 | Hydrolysis of triglycerides by immobilized thermostable lipase from humicola lanuginosa显示文摘 | IBRAHIM C O HISASHI S NAOMICHI N | 1988 | Agric Biol Chem1988，52，1： | 1 |
| 13 | Chronological constraints on the Paleoproterozoic Francevillian Group in Gabon显示文摘The Francevillian Group in Gabonese Republic was recently established as a typical sedimentary sequence for the Paleoproterozoic.However,its age is rather poorly constrained,mainly based on Rb-Sr and Nd-Sm datings.This study reports new zircon data obtained from Chaillu massif and N'goutou complex,which constrain the protolith age of the basement orthogneisses and the igneous age of an intrusive granite,respectively.Most zircons from the orthogneisses are blue and exhibit oscillatory zoning in cathode-luminescence images.Zircons with lower common lead abundances tend to be distributed close to the concordia curve.Two age clusters around 2860 Ma and 2910 Ma are found in zircons plotted on the concordia curve.Based on the Th/U ratios of zircons,these ages correspond to the protolith ages of the orthogneisses,and the zircons are not metamorphic in origin.Syenites and granites were collected from the N'goutou complex that intrudes into the FA and FB units of the Francevillian Group.The granitoids exhibit chemical composition of A-type granite affinity.Half of zircons separated from the granite are non-luminous,and the remaining half exhibit obscure internal textures under cathode-luminescence observation.All zircon grains contain significant amounts of common lead;the lead isotopic variability is probably attributed to the mixing of two components in the zircons.The zircon radiogenic ^(207)Pb/^(206)Pb ratio is 0.13707 ± 0.0010.corresponding to a ^(207)Pb/^(206)Pb age of 2191 ± 13 Ma.This constrains the minimum depositional age of the FA and FB units.Furthermore,the FB unit consists of manganese-rich carbonate rocks and organic carbon-rich black shales with macroscopic fossils.Based on our age constraints,these organisms appeared in the study area just after the last Paleoproterozoic Snowball Earth event,in concert with global scale oxidation event encompassing the Snowball Earth. | Yusuke Sawaki Mathieu Moussavou Tomohiko Sato Kazue Suzuki Cédric Ligna Hisashi Asanuma Shuhei Sakata Hideyuki Obayashi Takafumi Hirata Amboise Edou-Minkoinko | 2017 | Geoscience Frontiers2017，8，2： | 0 |
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