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    题名 作者 年代 出处 被引量
1Time range of Mesozoic tectonic regime inversion in eastern North China Block显示文摘An important tectonic inversion took place in eastern North China Block(NCB) during Mesozoic, which caused a great lithosphere thinning, reconstruction of basin-range series, powerful interaction between mantle and crust, a vast granitic intrusion and volcanism, and large-scale metallogenic explosion. The time range of the Mesozoic tectonic regime inversion in the eastern North China Block is one of the key issues to understand mechanism of tectonic regime inversion. Our updated results for recognizing the time range are mainly obtained from the following aspects: structural analyses along northern and southern margins of the NCB and within the NCB for revealing tectonic inversion from compression to extension and structural striking from ~EW to NNE; geothermic analyses of the eastern sedimental basins for a great change of thermal history and regime; basin analysis for basin inversion from compression to extension and basin migration from ~EW to NNE; petrological and geochemical studies of volcanic rocks and lowermost crust xenoliths for recognizing peak period of mantle upwelling and intense interaction between mantle and crust, and main metallogenic epoch. All the studies of the above give the same time range from~150-140 Ma to ~110-100Ma, peaking at ~120 Ma.ZHAI Mingguo ZHU Rixiang LIU Jianming MENG Qingren HOU Quanlin HU Shengbiao LIU Wei LI Zhong ZHANG Hongfu ZHANG Huafeng 2004Science China Earth Sciences2004,47,2:89
2Exogenous plant MIR168a specifically targets mammalian LDLRAPI: evidence of cross-kingdom regulation by microRNA显示文摘Lin Zhang Dongxia Hou Xi Chen Donghai Li Lingyun Zhu Yuj ing Zhang Jing Li Zhen Bian Xiangying Liang Xing Cai Yuan Yin Cheng Wang Tianfu Zhang Dihan Zhu Dianmu Zhang Jie Xu Qun Chen Yi Ba Jing Liu Qiang Wang Jianqun Chen Jin Wang Meng Wang Qipeng Zhang Junfeng Zhang Ke Zen Chen-Yu Zhang 2012Cell Research2012,22,1:155
3Improving Yield and Nitrogen Use Efficiency Simultaneously for Maize and Wheat in China: A Review显示文摘同时完成两高收益和高氮使用效率(NUE ) 与对食物,自然资源的弄空,和环境的恶化的增加的全球需求成为了主要挑战。作为在世界上的 N 化肥的最伟大的消费者,中国农民滥用了 N,并且因为 N 举起收益关系的有限理解,在庄稼 N 需求和 N 供应之间有差的 synchrony。处理这个问题,这研究为二个学生的不同收益范围评估了全部、动态的 N 要求庄稼(玉米和小麦) ,和到 N 管理策略的建议改进。整个植物的 N 未葬举起要求每谷物产量(N req ) 开始与谷物收益改进死亡了然后停滞,并且然而,大多数农民仍然相信更多的化肥和更高的谷物产量是同义的。当玉米产量增加了从时 < 7.5 到 > 12.0 Mg 哈 −1, N req 从 19.8 ~ 17.0 kg Mg −1 谷物减少了。为小麦,它为谷物产量从 27.1 kg Mg −1 谷物减少了 < 4.5 Mg 哈 −1 到为产量的 22.7 kg Mg −1 谷物 > 9.0 Mg 哈 −1 。同时,干燥物质的百分比和在中间迟了的成长季节的 N 累积与谷物产量显著地增加了,它显示 N 授精应该在中间迟了的阶段被集中当农民们经常在播种前或在早生长阶段期间使用了 N 化肥的多数时,匹配庄稼需求。我们因此开发了同时增加谷物产量和 NUE 的综合土壤庄稼系统管理策略。MENG Qingfeng YUE Shanchao HOU Peng CUI Zhenling CHEN Xinping 2016Pedosphere2016,26,2:51
4Proteomic analysis of human ovaries from normal and polycystic ovarian syndrome显示文摘Ma,X Fan,L Meng,Y Hou,Z Mao,YDL Wang,W Ding,W Liu,JY 2007南京医科大学学报(自然科学版)2007,27,11:20
5Overexpression of p27^(KIP1)induced cell cycle arrest in G_1 phase and subsequent apoptosis in HCC-9204 cell line显示文摘AIM We have previously reported that inducibleover-expression of Bak may prolong cell cycle inG1 phase and lead to apoptosis in HCC-9204 cells.This study is to investigate whether p27KIP1playsan important role in this process.METHODS In order to elucidate the exactfunction of p27KIP1in this process,a zinc induciblep27KIP1stable transfectant and transient p27KIP1-GFP fusion transfectant were constructed.Theeffects of inducible,p27KIP1on cell growth,cellcycle arrest and apoptosis were examined in themock,control pMD vector,and pMD-KIP1transfected HCC-9204 cells.RESULTS This p27KIP1-GFP transfectant maytransiently express the fusion gene.The cellgrowth was reduced by 35% at 48 h of p27KIP1induction with zinc treatment as determined bytrypan blue exclusion assay.These differencesremained the same after 72 h of p27KIP1expression,p27KIP1caused cell cycle arrest after24 h of induction,with 40% increase in G1population.Prolonged p27KIP1expression in thiscell line induced apoptotic cell death reflected byTUNEL assay.Fourty-eight h and 72 h of p27KIP1expression showed a characteristic DNA ladder onagarose gel electrophoresis. CONCLUSION Bak may induce cell cycle arrest inG1 phase through upregulating expression ofp27KIP1and subsequently lead to apoptosis inHCC-9204 cells.The p27KIP1-GFP fusion proteincan be transiently expressed in HCC-9204 cells.The inducible p27KIP1-expressing cell line providesa model to assess p27KIP1function.Jiang Li Xin Ke Yang Xin Xin Yu Meng Liang Ge Wen Liang Wang Jie Zhang Yun De Hou Department of Pathology,Fourth Military Medical University,Xi’an 710033,Shaanxi Province,China State Key Laboratory for Molecular Virology and Genetic Engineering,Beijing 100052,China Department of Dermatology,Beijing Hospital,Beijing 100016,China Institute of Radiation Medicine,Beijing 100085,China 2000World Journal of Gastroenterology2000,6,4:20
6Component Analysis and Free Radicals Scavenging Activity of Physalis alkekengi L. Polysaccharide显示文摘A crude polysaccharide was extracted from Physalis alkekengi L. fruit. HPLC was used for the component analysis of the polysaccharide. The results indicate that Physalis alkekengi L. polysaccharide(PAP) was composed of rhamnose, xylose, arabinose, galactose, and glucose. Free radicals scavenging activity of PAP was studied through 3 free radicals scavenging tests. PAP exhibited high scavenging effects on OH and DPPH radicals, and both the scavenging rates were about 80%. The scavenging rate of O2 radical was about 22%.CHENG Ying-kun LI Lei MENG Zhao-kun HOU A-li WU Yu-jie TENG Li-rong 2008Chemical Research in Chinese Universities2008,24,2:18
7Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol显示文摘Menopause is associated with dyslipidemia and an increased risk of cardio-cerebrovascular disease.The classic view assumes that the underlying mechanism of dyslipidemia is attributed to an insufficiency of estrogen.In addition to a decrease in estrogen, circulating follicle-stimulating hormone (FSH)levels become elevated at menopause.In this study,we find that blocking FSH reduces serum cholesterol via inhibiting hepatic cholesterol biosynthesis.First,epidemiological results show that the serum FSH levels are positively correlated with the serum total cholesterol levels,even after adjustment by considering the effects of serum estrogen,in addition,the prevalence of hypercholesterolemia is significantly higher in peri-menopausal women than that in premenopausal women.Furthermore,we generated a mouse model of FSH elevation by intraperitoneally injecting exogenous FSH into ovariectomized (OVX)mice,in which a normal level of estrogen (E2)was maintained by exogenous supplementation. Consistently,the results indicate that FSH,independent of estrogen,increases the serum cholesterol level in this mouse model. Moreover,blocking FSH signaling by anti-FSHβ antibody or ablating the FSH receptor (FSHR)gene could effectively prevent hypercholesterolemia induced by FSH injection or high-cholesterol diet feeding.Mechanistically,FSH,via binding to hepatic FSHRs, activates the Gi2α/β-arrestin-2/Akt pathway and subsequently inhibits the binding of FoxO1 with the SREBP-2 promoter,thus preventing FoxO1 from repressing SREBP-2 gene transcription.This effect,in turn,results in the upregulation of SREBP-2,which drives HMGCR nascent transcription and de novo cholesterol biosynthesis,leading to the increase of cholesterol accumulation.This study uncovers that blocking FSH signaling might be a new strategy for treating hypercholesterolemia during menopause, particularly for women in peri-menopause characterized by FSH elevation only.Yanjing Guo Meng Zhao Tao Bo Shizhan Ma Zhongshang Yuan Wenbin Chen Zhao He Xu Hou Jun Liu Zhenhai Zhang Qiang Zhu Qiangxiu Wang Xiaoyan Lin Zhongli Yang Min Cui Lu Liu Yujie Li Chunxiao Yu Xiaoyi Qi Qian Wang Haiqing Zhang Qingbo Guan Lifang Zhao Shimeng Xuan Huili Yan Yanliang Lin Li Wang Qihang Li Yongfeng Song Ling Gao Jiajun Zhao 2019Cell Research2019,29,2:16
8The Antagonistic Action of Abscisic Acid and Cytokinin Signaling Mediates Drought Stress Response in Arabidopsis显示文摘Xiaozhen Huang Lingyan Hou Jingjing Meng Huiwen You Zhen Li Zhizhong Gong Shuhua Yang Yiting Shi 2018Molecular Plant2018,11,7:15
9Liquefaction macrophenomena in the great Wenchuan earthquake显示文摘On May 12,2008 at 14:28,a catastrophic magnitude Ms 8.0 earthquake struck the Sichuan Province of China.The epicenter was located at Wenchuan(31.00oN,103.40oE).Liquefaction macrophenomena and corresponding destruction was observed throughout a vast area of 500 km long and 200 km wide following the earthquake.This paper illustrates the geographic distribution of the liquefaction and the relationship between liquefaction behavior and seismic intensity,and summarizes the liquefaction macrophenomena,including sandboils and waterspouts,ground subsidence,ground fi ssures etc.,and relevant liquefaction features.A brief summary of the structural damage caused by liquefaction is presented and discussed.Based on comparisons with liquefaction phenomena observed in the 1976 Tangshan and 1975 Haicheng earthquakes,preliminary analyses were performed,which revealed some new features of liquefaction behavior and associated issues arising from this event.The site investigation indicated that the spatial non-uniformity of liquefaction distribution was obvious and most of the liquefi ed sites were located in regions of seismic intensity VIII.However,liquefaction phenomena at ten different sites in regions of seismic intensity VI were also observed for the fi rst time in China mainland.Sandboils and waterspouts ranged from centimeters to tens of meters,with most between 1 m to 3 m.Dramatically high water/sand ejections,e.g.,more than 10 m,were observed at four different sites.The sand ejections included silty sand,fi ne sand,medium sand,course sand and gravel,but the ejected sand amount was less than that in the 1976 Tangshan earthquake.Possible liquefaction of natural gravel soils was observed for the fi rst time in China mainland.Chen Longwei Yuan Xiaoming Cao Zhenzhong Hou Longqing Sun Rui Dong Lin Wang Weiming Meng Fanchao Chen Hongjuan 2009Earthquake Engineering and Engineering Vibration2009,8,2:14
10Multi-scale design and optimization for solid-lattice hybrid structures and their application to aerospace vehicle components显示文摘By integrating topology optimization and lattice-based optimization,a novel multi-scale design method is proposed to create solid-lattice hybrid structures and thus to improve the mechanical performance as well as reduce the structural weight.To achieve this purpose,a two-step procedure is developed to design and optimize the innovative structures.Initially,the classical topology optimization is utilized to find the optimal material layout and primary load carrying paths.Afterwards,the solid-lattice hybrid structures are reconstructed using the finite element mesh based modeling method.And lattice-based optimization is performed to obtain the optimal crosssection area of the lattice structures.Finally,two typical aerospace structures are optimized to demonstrate the effectiveness of the proposed optimization framework.The numerical results are quite encouraging since the solid-lattice hybrid structures obtained by the presented approach show remarkably improved performance when compared with traditional designs.Chuang WANG Jihong ZHU Manqiao WU Jie HOU Han ZHOU Lu MENG Chenyang LI Weihong ZHANG 2021Chinese Journal of Aeronautics2021,34,5:14
11Tomato lncRNA23468 functions as a competing endogenous RNA to modulate NBS-LRR genes by decoying miR482b in the tomato-Phytophthora infestans interaction显示文摘Our previous studies indicated that tomato miR482b could negatively regulate the resistance of tomato to Phytophthora infestans and the expression of miR482b was decreased after inoculation with P.infestans.However,the mechanism by which the accumulation of miR482b is suppressed remains unclear.In this study,we wrote a program to identify 89 long noncoding RNA(lncRNA)-originated endogenous target mimics(eTMs)for 46 miRNAs from our RNA-Seq data.Three tomato lncRNAs,lncRNA23468,lncRNA01308 and lncRNA13262,contained conserved eTM sites for miR482b.When lncRNA23468 was overexpressed in tomato,miR482b expression was significantly decreased,and the expression of the target genes,NBS-LRRs,was significantly increased,resulting in enhanced resistance to P.infestans.Silencing lncRNA23468 in tomato led to the increased accumulation of miR482b and decreased accumulation of NBS-LRRs,as well as reduced resistance to P.infestans.In addition,the accumulation of both miR482b and NBS-LRRs was not significantly changed in tomato plants that overexpressed lncRNA23468 with a mutated eTM site.Based on the VIGS system,a target gene of miR482b,Solyc02g036270.2,was silenced.The disease symptoms of the VIGS-Solyc02g036270.2 tomato plants were in accordance with those of tomato plants in which lncRNA23468 was silenced after inoculation with P.infestans.More severe disease symptoms were found in the modified plants than in the control plants.Our results demonstrate that lncRNAs functioning as eTMs may modulate the effects of miRNAs in tomato and provide insight into how the lncRNA23468-miR482b-NBS-LRR module regulates tomato resistance to P.infestans.Ning Jiang Jun Cui Yunsheng Shi Guanglei Yang Xiaoxu Zhou Xinxin Hou Jun Meng Yushi Luan 2019Horticulture Research2019,6,1:12
12Osteopontin knockdown suppresses the growth and angiogenesis of colon cancer cells显示文摘AIM:To investigate the effects of osteopontin(OPN)gene expression knockdown on colon cancer Lovo cells in vitro.METHODS:Four candidate small interfering RNA(siRNA)constructs targeting the OPN gene and a scrambled control sequence(NC-siRNA)were synthesized and inserted into a pGPU6/GFP/Neo expression vector.After confirmation by restriction enzyme digestion and DNA sequencing,the recombinant plasmids were subsequently transfected into a human colon cancer cell line(Lovo)using a liposome transfection method.Stably transfected cells were maintained with G418 selection and referred to as Lovo-OPN-1,-2,-3,-4,and Lovo-NC cells.Knockdown efficiency of each of the four siRNA constructs was determined by realtime reverse transcription polymerase chain reaction assays and western blotting,and the construct with the most effective silencing was used for subsequent experiments.Cell proliferation,adhesion,and Matrigel invasion assays were performed to analyze the effects of OPN knockdown in stably transfected Lovo cells.The levels of four angiogenic factors,namely vascular endothelial growth factor(VEGF),matrix metalloproteinase(MMP)-2,MMP-9 and urokinase plasminogen activator were detected by enzyme-linked immunosorbent assays(ELISA).RESULTS:Recombinant vectors containing OPNspecific and scrambled siRNA sequences were successfully constructed and stably transfected into Lovo cells.Compared with the control Lovo and Lovo-NC cells,the levels of OPN mRNA and protein expression in LovoOPN-1,-2,-3,and-4 were significantly reduced(all P<0.05),with the most efficient reduction observed in Lovo-OPN-4 cells(P<0.05).Relative to untransfected Lovo cells,OPN mRNA expression levels in Lovo-NC and Lovo-OPN-4 cells were 1.008±0.067 and 0.160±0.023,respectively.The relative OPN protein expression levels in Lovo,Lovo-NC,and Lovo-OPN-4 cells were 3.024±0.211,2.974±0.630,and 0.121±0.008,respectively.Moreover,transfection with the scrambled sequence had no effect on the expression of OPN.After24,48,72,and 96 h of cultivation,absorption values at 450 nm to assess proliferation of Lovo-OPN-4 cells were 0.210±0.017,0.247±0.024,0.314±0.037,and 0.359±0.043,respectively,which were significantly lower than those of Lovo(0.244±0.031,0.313±0.024,0.513±0.048 and 0.783±0.051)and LovoNC cells(0.241±0.029,0.309±0.022,0.563±0.023,and 0.735±0.067)(all P<0.05).The absorption values at 595 nm,which were measured in a cell adhesion assay,showed that adhesion of Lovo-OPN-4 cells(0.215±0.036)was significantly decreased compared to Lovo(0.490±0.037)and Lovo-NC cells(0.462±0.043)(P<0.05).The number of invasive Lovo-OPN-4 cells(16.1±1.9)was also significantly decreased compared to Lovo(49.9±5.4)and Lovo-NC cells(48.8±4.5)(P<0.05).ELISA assays showed significant reductions in Lovo-OPN-4 cells compared to Lovo and Lovo-NC cells with regard to the expression of VEGF(1687.85±167.84 ng/L vs 2348.54±143.80 ng/L and 2284.39±138.62 ng/L,respectively),MMP-2(2966.07±177.36μg/L vs 4084.74±349.54μg/L and 4011.41±424.48μg/L,respectively),MMP-9(3782.89±300.64μg/L vs5062.90±303.02μg/L and 4986.38±300.75μg/L,respectively)and uPA(1152.69±120.79μg/L vs1380.90±147.25μg/L and 1449.80±189.92μg/L,respectively)(all P<0.05).CONCLUSION:Knockdown of OPN gene expression suppresses colon cancer cell growth,adherence,invasion,and expression of angiogenic factors.Xin-Lin Wu Kai-Jin Lin Ai-Ping Bai Wan-Xiang Wang Xing-Kai Meng Xiu-Lan Su Ming-Xing Hou Pei-De Dong Jun-Jing Zhang Zhao-Yang Wang Lin Shi 2014World Journal of Gastroenterology2014,20,30:12
13Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy显示文摘瞄准: 估价 Vam3 (Amurensis H ) 的功效, resveratrol 的二聚的衍生物,在禁止香烟导致烟的 autophagy。Ji SHI Ning YIN Ling-ling XUAN Chun-suo YAO Ai-min MENG Qi HOU 2012Acta Pharmacologica Sinica2012,33,7:12
14TiO_2-loaded activated carbon fiber:Hydrothermal synthesis,adsorption properties and photo catalytic activity under visible light irradiation显示文摘TiO_2-loaded activated carbon fibers(ACF) were prepared by a hydrothermal method.The samples were characterized by scanning electron microscopy(SEM),X-ray diffraction(XRD),Fourier transform infrared(FT1R) spectrometry and UV-vis diffuse reflectance spectra(DRS).SEM images showed that the TiO_2nanoparticles were deposited on the surface of ACF,and the particle size and loading amount of TiO_2were varied by changing the initial concentration of tetrabutyl titanate(TBOT).The results of an ash experiment showed that the loading amounts of TiO_2 were 18.4%,43.3%,52.5%,75.1%,and 91.1%for initial concentrations of TBOT of 0.07,014,0.21,0.28,and 0.35 mol/L,respectively.Physical interactions played an important role in the formation of TiO_2/ACF composite fibers that absorb UV and visible light.Compared with those of ACF,improved adsorption and photocatalytic activity toward Rhodamine B(RhB)were observed for TiO_2/ACF composite fiber.The Rhodamine B could be removed efficiently by TiO_2/ACF composite fibers,and the TiO_2 loading amount had a significant effect on the photocatalytic activity of TiO_2/ACF composite fibers.Hao Meng Wei Hou Xinxin Xu Junli Xu Xia Zhang 2014Particuology2014,12,3:10
15Phase-field simulation for the evolution of solid/liquid interface front in directional solidification process显示文摘In this study, the phase field method was used to study the multi-controlling factors of dendrite growth in directional solidification. The effects of temperature gradient, propelling velocity, thermal disturbance and growth orientation angle on the growth morphology of the dendritic growth in the solid/liquid interface were discussed. It is found that the redistribution of solute leads to multilevel cavity and multilevel fusion to form multistage solute segregation, and the increase of temperature gradient and propelling velocity can accelerate the dendrite growth of directional solidification, and also make the second dendrites more developed, which reduces the primary distance and the solute segregation. When the temperature gradient is large, the solid-liquid interface will move forward in a flat interface mode,and the thermal disturbance does not affect the steady state behavior of the directionally solidified dendrite tip. It only promotes the generation and growth of the second dendrites and forms the asymmetric dendrite. Meanwhile, it is found that the inclined dendrite is at a disadvantage in the competitive growth compared to the normal dendrite, and generally it will disappear. When the inclination angle is large, the initial primary dendrite may be eliminated by its secondary or third dendrite.Yuhong Zhao Bing Zhang Hua Hou Weipeng Chen Meng Wang 2019Journal of Materials Science & Technology2019,35,6:10
16Effect of Heficobacter pylori Eradication on Reflux Esophagitis Therapy: A Multi-center Randomized Control Study显示文摘Yan Xue Li-Ya Zhou San-Ren Lin Xiao-Hua HOU Zhao-Shen Li Min-Hu Chen Xiu-E Yan Ling-Mei Meng Jing Zhang Jing-Jing Lu 2015Chinese Medical Journal2015,,8:9
17Mechanism of hydro-viscous soft start of belt conveyor显示文摘The mechanism of a hydro-viscous soft start is of great importance in the design of a hydro-viscous clutch and its control system. To explain the mechanism of a hydro-viscous soft start, the startup process of a belt conveyor was numerically analyzed with the modified Reynolds equation, an energy equation and a temperature-viscosity equation. The effect of temperature and grooves of the friction disk surface on torque transfer and load capacity of the oil film have also been analyzed. The results show that 1) the grooves are the basis of forming dynamic pressure but they may reduce the capacity of torque transfer to a certain extent, 2) during the startup process, temperature has little effect on torque transfer and load capacity and the variation in load capacity of the oil film is very small, indicating that it is preferable to use the flow rate as a control object than the pressure of the feed cylinder. The results have been verified by an experiment.MENG Qing-rui HOU You-fu 2008Journal of China University of Mining and Technology2008,18,3:9
18Geological Fluid Mapping in the Tongling Area:Implications for the Paleozoic Submarine Hydrothermal System in the Middle-Lower Yangtze Metallogenic Belt,East China显示文摘The Tongling area is one of the 7 ore-cluster areas in the Middle-Lower Yangtze metallogenic belt,East China,and has tectonically undergone a long-term geologic history from the late Paleozoic continental rifting,through the Middle Triassic continent-continent collision to the Jurassic-Cretaceous intracontinental tectono-magmatic activation.The Carboniferous sedimentary-exhalative processes in the area produced widespread massive sulfides with ages of 303-321 Ma,which partly formed massive pyrite-Cu deposits,but mostly provided significant sulfur and metals to the skarn Cu mineralization associated with the Yanshanian felsic intrusions. To understand the Carboniferous submarine hydrothermal system,an area of about 1046 km^2 was chosen to carry out the geological fluid mapping.Associated with massive sulfide formation,footwall sequences 948 m to 1146m thick,composed of the Lower Silurian-Upper Devonian sandstone,siltstone and thin-layered shale,were widely altered.This hydrothermal alteration is interpreted to reflect large- scale hydrothermal fluid flow associated with the late Paleozoic crustal rifting and subsidence.Three hydrothermal alteration types,i.e.,deep-level semiconformable silicification(S_1),fracture-controlled quartz-sericite-pyrite alteration(S_(2-3)),and upper-level sub-discordant quartz-sericite-chlorite alteration(D_3),were developed to form distinct zones in the mapped area.About 50-m thick semiconformable silicification zones are located at~1-km depth below massive sulfides and developed between an impermeable shale caprock(S_1)and the underlying Ordovician unaltered limestone. Comparisons with modern geothermal systems suggest that the alteration zones record a sub-seafloor aquifer with the most productive hydrothermal fluid flow.Fracture-controlled quartz-sericite-pyrite alteration formed transgressive zones,which downward crosscut the semiconformable alteration zones, and upwards grade into sub-discordant alteration zones that enveloped no economic stringer- stockwork zones beneath massive sulfides.This transgressive zone likely marks an upflow path of high- flux fluids from the hydrothermal aquifer.Lateral zonation of the sub-discordant alteration zones and their relationship to overlying massive sulfide lenses suggest lateral flows and diffusive discharging of the hydrothermal fluids in a permeable sandstone sequence.Three large-sized,14 middle-small massive sulfide deposits,and 40 massive sulfide sites have been mapped in detail.They show regional strata- bound characters and two major styles,i.e.,the layered sheet plus strata-bound stringer-style and the mound-style.Associated exhalite and chemical sedimentary rock suites include(1)anhydrite-barite,(2) jasper-chert,(3)Mg-rich mudstone-pyrite shale,(4)barite lens,(5)siderite-Fe-bearing dolomite,and (6)Mn-rich shale-mudstone,which usually comprise three sulfide-exhalite cyclic units in the area. The spatial distribution of these alteration zones(minerals)and associated massive sulfides and exhalites,and regional variation inδ^(34)S of hydrothermal pyrite and inδ^(18)O-δ^(34)C of hanging wall carbonates,suggest three WNW-extending domains of fluid flow,controlled by the basement faults and syn-depositional faults.Each fluid domain appears to have at least two upflow zones,with estimated even spacing of about 5-8 km in the mapped area.The repeated appearance of sulfide-sulfate or sulfide-carbonate rhythmic units in the area suggests episodically venting of fluids through the upflow conduits by breaking the overlying seals of the hydrothermal aquifer.HOU Zengqian YANG Zhusen MENG Yifeng ZENG Pusheng LI Hongyang XU Wenyi 2007Acta Geologica Sinica(English Edition)2007,81,5:8
19A novel two-layered optical satellite network of LEO/MEO with zero phase factor显示文摘Optical satellite communication has advantages over the RF satellite communication in capacity, speed, secrecy and anti-interference.Space information superhighway composed of GEO/MEO/LEO satellites which are linked by optical inter-satellite links(OISL) would play important roles in communication, navigation, martial recon, remote sensing and deep space exploration.A novel LEO/MEO two-layered optical satellite network with global coverage is designed with the street-of-coverage technique.The layer of LEO satellites is the walker-delta constellation with zero phase factor and has the quasi-stable logical structure of Mesh.Equatorial and polar orbit satellites constitute the layer of MEO satellite, which can cover LEO layer effectively.Rising satellites of the system can provide 99.9% of coverage for the whole globe and 100% for China averagely.The network can provide a minimum elevation angle at 21 ? with single-satellite visibility for China, and at 16 ? with the dual-satellite visibility.Simulation results of the inter-satellite links show LEO constellation of zero phase factor outperforms non-zero phase factor constellations in azimuth angle, elevation angle and distance, which is very fit for the OISL.Simulation results of the communication performance indicate a little difference between short wave band and long wave band at low communication speed(several Gbit/s);however, the wave band at 1550 nm is a better choice at high communication speed(100 Gbit/s).LI YongJun , WU JiLi, ZHAO ShangHong, MENG Wen, MA LiHua, SHI Lei, CHU XingChun, HOU Rui & LI Tian Telecommunication Engineering Institute, Air Force Engineering University, Xi’an 710077, China 2010Science China(Information Sciences)2010,53,6:8
20Therapeutic effects of adipose-derived stem cells-based microtissues on erectile dysfunction in streptozotocin-induced diabetic rats显示文摘试图探索脂肪质导出干细胞(ADSC ) 的治疗学的效果的这研究在导致的 streptozotocin (STZ ) 把 microtissues (MT ) 基于可勃起的机能障碍(编辑) 糖尿病的老鼠。56 只 8-week-old Sprague-Dawley 老鼠收到了 STZ 的 intraperitoneal 注射(60 mg kg −1), 和 8 个星期以后,坚定的糖尿病的老鼠随机收到了 intracavernous (IC ) 磷酸盐缓冲区答案(PBS ) 的注射, ADSC,或 MT。另一八正常老鼠同等地得到了 PBS 的 IC 注射。MT 与一个挂的落下方法被产生,并且注射房间在注射 ADSC 、注射 MT 的老鼠被追踪。在处理, intracavernous 压力(ICP ) ,在阴茎海绵体(CC ) 的组织病理学说的变化,和功能的蛋白质以后的四个星期被是。老鼠 cytokine 抗体数组被用来检测 ADSC 或 MT lysate。结果证明 MT 表示了脉管的 endothelial 生长因素(VEGF ) ,神经生长因素(NGF ) ,和肿瘤坏死刺激因素的 gene-6 (TSG-6 ) 。MT 注射比 ADSC 注射和 MT 治疗改进 ICP 的有更高的保留,氮的氧化物 synthase (nNOS ) 表示,光滑的肌肉,和 endothelial 在糖尿病的老鼠满足的 neuronal,在 CC 的改善局部炎症更好。因此,我们的调查结果证明 MT 的那 IC 注射在导致 STZ 的糖尿病的老鼠改进可勃起的功能和组织病理学说的变化并且看起来比传统的 ADSC 更有希望。内在的机制包含伴有 neuroprotection 和 paracrine 因素的反煽动性的行为的增加的房间保留。Feng Zhou Hua Xin Yong-De Xu Hong-En Lei Bi-Cheng Yang Rui-Li Guan Meng Li Jian-Quan Hou Zhong-Cheng Xin 2017Asian Journal of Andrology2017,19,1:8
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