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410篇 您的检索式:作者名="HOWARD J B"
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1Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data.Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat 2013World Journal of Gastroenterology2013,19,36:7
2Formation of polycyclic arom atic hydrocarbons and their growth to soot: A review of chemical reaction pathways显示文摘Richter H Howard J B 2000Progress in Energy and Combustion Science2000,26,46:1
3Sand transport model of barchan dune equilibrium显示文摘Howard A D Morton J B Gad-el-Hak M 1978Sedimentology1978,25,:1
4Coal devolatilization and hydrogasification显示文摘Anthony D B Howard J B 1976AICHE Journal1976,22,4:1
5Metabolic syndrome and risk of incident cardiovascular events and death: a systematic re- view and meta-analysis of longitudinal studies 显示文摘Gami AS Witt B J Howard DE 2007J Am Coil Car- diol2007,49,4:1
6Two monoclonal an tibodies(cc17,cc29)recognizing an antigen(Bo5)on bovine T lymphocytes,analogous to human CD5显示文摘Howard C J,Parsons K P,Jones B V 1988Vet Immunol1988,13,:1
7The Arabidopsis ribonuclease gene RNS1 is tightly controlled in response to phosphate limitation显示文摘BARIOLA P A HOWARD C J TAYLOR C B 1994The Plant Journal1994,6,5:1
8A context- based theory of recency and contiguity in free recall 显示文摘Sederberg P B Howard M W Kahana M J 2008Psychological Review2008,115,4:1
9Rapid Devolatilization and Hydrogasification of Bimmlnous Coal 显示文摘Anthony D B Howard J B Hottel H C 1976Fuel1976,55,2:1
10Hip displacement in cerebral palsy 显示文摘Soo B Howard J J Boyd RN 2006J Bone Joint Surg Am2006,88,1:1
11Protein expression profiling identifies macrophage migration inhibitory factor and cyclophilin A as potential molecular targets in non-small cell lung cancer 显示文摘Campa M J Wang MZ Howard B 2003Cancer Res2003,63,7:1
12Fullerenic nanostructures in flames 显示文摘DASCHLWDHURY K HOWARD J B VANDERSANDE J B 1996Journal of Materials Research1996,11,2:1
13Using magnetic resonance imaging to monitor CH4hydrate formation and spontaneous conversion of CH4hydrate to CO2hydrate in porous media显示文摘Baldwin B A Stevens J Howard J 2009Magnetic Resonance Imaging2009,27,5:1
14Development of a sensitive picrate method to determine total cyanide and acetone cyanohydrins contents of gari from cassava显示文摘Howard B J 2009Food Chemistry2009,,113:1
15Pressure and Temperature Effects in Bituminous Coal Pyrolysis:Experimental Observations and a Transient lumped-parameter Model显示文摘Griffin T P Howard J B Peters W A 1994Fuel1994,73,4:1
16Breaking and Entering - host Penetration by the Fungal Rice Blast Pathogen Magnaporthe grisea显示文摘HOWARD R J VALENT B 1996Annu Rev Microbiol1996,50,:1
17Flame synthesis of single-walled carbon nanotubes显示文摘Height M J Howard J B Tester J W 2004Carbon2004,42,11:1
18Simulation model of erosion and deposition on a barchan dune 显示文摘HOWARD A D MORTON J B 1977NASA CR-28381977,,:1
19Flame synthesis of single-walled carbon nanotubes 显示文摘Murray J Height Jack B Howard Jefferson W Tester 2004Carbon2004,42,:1
20Enhanced fertility after diagnostic hysterosalpingography:the debate continues显示文摘Anthony J David B Howard E 2005Am J Roentgenol2005,184,1:1
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