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| 1 | Computational neuroscience:a frontier of the 21^st century显示文摘THEORY IN NEUROSCIENCE The human brain is a biological organ,weighing about three pounds or 1.4 kg,that determines our behaviors,thoughts,emotions and consciousness.Although comprising only 2%of the total body weight,the brain consumes about 20%of the oxygen entering the body.With the expensive energy demand,the brain enables us to perceive and act upon the external world,as well as reflect on our internal thoughts and feelings. | Xiao-Jing Wang Hailan Hu Chengcheng Huang Henry Kennedy Chengyu Tony Li Nikos Logothetis Zhong-Lin Lu Qingming Luo Mu-ming Poo Doris Tsao Si Wu Zhaohui Wu Xu Zhang Douglas Zhou | 2020 | National Science Review2020，7，9： | 4 |
| 2 | Construction of Photoresponsive 3D Structures Based on Triphenylethylene Photochromic Building Blocks显示文摘Photoresponsive materials have been widely used in sensing,bioimaging,molecular switches,information storage,and encryption nowadays.Although a large amount of photoresponsive materials have been reported,the construction of these smart materials into precisely prescribed complex 3D geometries is rarely studied.Here we designed a novel photoresponsive material methyl methacrylate containing triphenylethylene(TrPEF_(2)-MA)that can be directly used for digital light processing(DLP)3D printing.Based on TrPEF_(2)-MA,a series of photoresponsive 3D structures with reversible color switching under ultraviolet/visible light irradiations were fabricated.These complex photoresponsive 3D structures show high resolutions(50μm),excellent repeatability(25 cycles without fatigue),and tunable saturate color degrees.Multicomponent DLP 3D printing processes were also carried out to demonstrate their great properties in information hiding and information-carrying properties.This design strategy for constructing photoresponsive 3D structures is attractive in the area of adaptive camouflage,information hiding,information storage,and flexible electronics. | Xiayu Zhang Fukang Liu Beibei Du Rongjuan Huang Simin Zhang Yunfei He Hailan Wang Jingjing Cui Biao Zhang Tao Yu Wei Huang | 2022 | Research2022，，4： | 1 |
| 3 | Direct bandgap engineering with local biaxial strain in few-layer MoS2 bubbles显示文摘Nano Research volume 13,pages2072–2078(2020)Cite this article 211 Accesses Metrics details Abstract Strain engineering provides an important strategy to modulate the optical and electrical properties of semiconductors for improving devices performance with mechanical force or thermal expansion difference.Here,we present the investigation of the local strain distribution over few-layer MoS2 bubbles,by using scanning photoluminescence and Raman spectroscopies.We observe the obvious direct bandgap emissions with strain in the few-layer MoS2 bubble and the strain-induced continuous energy shifts of both resonant excitons and vibrational modes from the edge of the MoS2 bubble to the center(10μm scale),associated with the oscillations resulted from the optical interference-induced temperature distribution.To understand these results,we perform ab initio simulations to calculate the electronic and vibrational properties of few-layer MoS2 with biaxial tensile strain,based on density functional theory,finding good agreement with the experimental results.Our study suggests that local strain offers a convenient way to continuously tune the physical properties of a few-layer transition metal dichalcogenides(TMDs)semiconductor,and opens up new possibilities for band engineering within the 2D plane. | Yang Guo Bin Li Yuan Huang Shuo Du Chi Sun Hailan Luo Baoli Liu Xingjiang Zhou Jinlong Yang Junjie Li Changzhi Gu | 2020 | Nano Research2020，13，8： | 1 |
| 4 | Echinacea purpurea-derived homogeneous polysaccharide exerts anti-tumor efficacy via facilitating M1 macrophage polarization显示文摘Echinacea purpurea modulates tumor progression,but the underlying mechanism is poorly defined.We isolated and purified a novel homogeneous polysaccharide from E.purpurea(EPPA),which was shown to be an arabinogalactan with a mean molecular mass(Mr)of 3.8×10^(4)Da and withα-(1→5)-L-Arabinan as the backbone and a-L-Araf-(1→,→6)-b-D-Galp-(1→,and →4)-α-D-GalpA-(1/as the side chains.Interestingly,oral administration of EPPA suppresses tumor progression in vivo and shapes the immune cell profile(e.g.,facilitating M1 macrophages)in tumor micro-environment by single-cell RNA sequencing(scRNA-seq)analysis. | Wenkai Ren Junfeng Ban Yaoyao Xia Fang Zhou Caihong Yuan Huanhuan Jia Hailan Huang Mingmin Jiang Minjian Liang Zhaodong Li Youyong Yuan Yulong Yin Hong Wu | 2023 | The Innovation2023，4，2： | 1 |
| 5 | Recent Development of Photodeformable Crystals:From Materials to Mechanisms显示文摘Photodeformable materials are a class of molecules that can convert photon energy into mechanical energy,which have attracted tremendous attention in the last few decades.Owing to their unique photoinduced deformable properties,including fast lightresponse and diverse mechanical behaviors,photodeformable materials have exhibited great potential in many practical applications such as actuators,photoswitches,artificial muscles,and bioimaging.In this review,we sort out the current state of photodeformable crystals and classify them into six categories by molecular structures:diarylethenes,azobenzenes,anthracenes,olefins,triarylethylenes,and other systems.Three distinct light-responsive mechanisms,photocyclization,trans-cis isomerization,and photodimerization,are revealed to play significant roles in the molecular photodeformation.Their corresponding photodeformable behaviors such as twisting,bending,hopping,bursting,and curling,as well as the potential applications,are also discussed.Furthermore,the challenges and prospective development directions of photodeformable crystals are highlighted. | Cheng Huang Rongjuan Huang Simin Zhang Haodong Sun Hailan Wang Beibei Du Yuxin Xiao Tao Yu Wei Huang | 2021 | Research2021，，1： | 1 |
| 6 | Recent Development of Photodeformable Crystals: From Materials to Mechanisms显示文摘Photodeformable materials are a class of molecules that can convert photon energy into mechanical energy,which have attracted tremendous attention in the last few decades.Owing to their unique photoinduced deformable properties,including fast lightresponse and diverse mechanical behaviors,photodeformable materials have exhibited great potential in many practical applications such as actuators,photoswitches,artificial muscles,and bioimaging.In this review,we sort out the current state of photodeformable crystals and classify them into six categories by molecular structures:diarylethenes,azobenzenes,anthracenes,olefins,triarylethylenes,and other systems.Three distinct light-responsive mechanisms,photocyclization,trans-cis isomerization,and photodimerization,are revealed to play significant roles in the molecular photodeformation.Their corresponding photodeformable behaviors such as twisting,bending,hopping,bursting,and curling,as well as the potential applications,are also discussed.Furthermore,the challenges and prospective development directions of photodeformable crystals are highlighted. | Cheng Huang Rongjuan Huang Simin Zhang Haodong Sun Hailan Wang Beibei Du Yuxin Xiao Tao Yu Wei Huang | 2022 | Research2022，，1： | 0 |
| 7 | Planning Policies Towards Shanghai's Rapid Urban Development | Huang Fuxiang Official, Shanghai Academy of Urban Planning and Design. Zheng Hailan | 1992 | China City Planning Review1992，9，2： | 0 |
| 8 | Synthesis of Caffeic Acid Sulphonamide Derivatives and Preliminary Exploration of Their Biological Applications显示文摘Stnictural modification of native compounds is an effective way to develop new dmgs with increased pharmacological activities and improved material characteristics.In this study,cafteic acid sulphonamide derivatives(CSs)were synthesised by conjugating sulphonamides to the backbone of cafteic acid.The structures of these derivatives were elucidated by means of Fourier traiisfonn infrared spectroscopy(FTIR),1H NMR,13C NMR,and electrospray ionization mass spectroscopy(ESI-MS).A content determination method was established by ultraviolet detection.The lipophilicity,2,2-diphenyl-l-picrylhydrazy free radical(DPPH)scavenging capacity,anti-coagulant eitects,anti-bacterial activity,cytotoxicity,in vitro anti-proliterative activity against tumour cells,and the ability of the compounds to promote the proliferation of chondrocytes were evaluated.The results indicate that CSs exliibit strong DPPH scavenging activity,high lipophilicity,good anti-coagulant activities,wide anti-bacterial activity range,low cytotoxicity,and an excellent ability to promote chondrocyte proliferation. | PENG Xiaoyu ZHAO Anran HUANG Kelin HU Tingju LIU Burning HUANG Yan CHEN Hailan CHAI Ling LIN Cuiwu | 2020 | Chemical Research in Chinese Universities2020，36，5： | 0 |
| 9 | 肝动脉栓塞化疗联合肝复乐治疗晚期肝癌临床疗效观察(英文)显示文摘Objective: The aim of this study was to evaluate the efficacy of transcatheter arterial chemoembolization (TACE) combined with a Chinese compound preparation of ganfule on advanced hepatocellular carcinoma (HCC). Methods: The study population consisted of 132 advanced HCC patients with Child-pugh A/B. Tumor in all patients was involved with main trunk of portal vein and/or inferior vena cava, or local lymph node metastasis, or distant metastasis. TACE combined with ganfule were performed in 65 patients with advanced HCC (interventional treatment group), 67 patients were treated with traditional Chinese herbal drug alone (Chinese herb group). The prime end point was overall survival (OS), and prognostic factors were analyzed. Results: The median OS was 205 days [95% confidence interval (CI), 155-255 days] in interventional treatment group and 127 days (95% CI, 70-184 days) in Chinese herb group (P<0.05). The 6-month, 1-year, and 2-year OS rates were 58.9%, 29.1%, 7.7% in interventional treatment group, and 33.3%, 12.3%, 1.8% in Chinese herb group, respectively. The portal vein thrombosis, ECOG performance status (PS) were independent prognostic factors for OS. Conclusion: Ttranscatheter arterial chemoembolization combined with a Chinese compound preparation of ganfule could greatly prolong the OS of advanced HCC patients. The portal vein thrombosis and ECOG PS were independent prognostic factors for OS. | Mingzhi Hao Hailan Lin Qizhong Chen Yubin Hu Dong Zhou Ping Huang YunBin Ye | 2013 | The Chinese-German Journal of Clinical Oncology2013，12，1： | 0 |
| 10 | Remarks on Centers of Rings显示文摘It is proved that for matrices A,B in the n by n upper triangular matrix ring T_(n)(R)over a domain R,if AB is nonzero and central in T_(n)(R)then AB=BA.The n by n full matrix rings over right Noetherian domains are also shown to have this property.In this article we treat a ring property that is a generalization of this result,and a ring with such a property is said to be weakly reversible-over-center.The class of weakly reversible-over-center rings contains both full matrix rings over right Noetherian domains and upper triangular matrix rings over domains.The structure of various sorts of weakly reversible-over-center rings is studied in relation to the questions raised in the process naturally.We also consider the connection between the property of being weakly reversible-over-center and the related ring properties. | Juan Huang Hailan Jin Tai Keun Kwak Yang Lee Zhelin Piao | 2021 | Algebra Colloquium2021，28，1： | 0 |
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