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| 1 | Hyperthermic intraperitoneal chemotherapy for gastric and colorectal cancer in China's Mainland显示文摘AIM:To investigate the current status of peritoneal carcinomatosis(PC) management,as well as the usage of cytoreductive surgery(CRS) and hyperthermic intraperitoneal chemotherapy(HIPEC) in China's Mainland.METHODS:A potentially curative therapeutic strategy for selecting patients with PC,known as 'Techniques',consists of CRS in combination with HIPEC.A systemic search of published works and clinical trials was performed.Additional papers were retrieved by crosschecking references and obtaining information from Chinese oncologists and relevant conferences.One hundred and one papers and one registered clinical trial on HIPEC were included.RESULTS:A literature review identified 86 hospitals in 25 out of all 31 areas of China's Mainland that perform HIPEC.The earliest report included in our survey was published in 1993.Different approaches to HIPEC have been utilized,i.e.palliative,prophylactic,and possiblycurative treatment.Only one center has consistently performed HIPEC according to the 'Sugarbaker Protocol',which involves evaluating the extent of PC with peritoneal cancer index and the results of CRS with the completeness of cytoreduction.Positive preliminary results were reported:7 of 21 patients with PC survived,free of tumors,during an 8-43-mo follow-up period.Hyperthermic strategies that include HIPEC have been practiced for a long time in China's Mainland,whereas the 'Sugarbaker Protocol/Techniques' has been only rarely implemented in China.The Peritoneal Surface Oncology Group International hosts a biannual workshop with the intent to train more specialists in this field and provide support for the construction of quality treatment centers,especially in developing countries like China,whose population is huge and has a dramatically increased incidence of cancer.CONCLUSION:To popularize Sugarbaker Protocol/Techniques in China's Mainland in PC management arising from gastric cancer or colorectal cancer will be the responsibility of the upcoming Chinese Peritoneal Surface Oncology Group. | Tao Suo Haile Mahteme Xin-Yu Qin | 2011 | World Journal of Gastroenterology2011，17，8： | 18 |
| 2 | Diabetes mellitus is associated with increased mortality during tuberculosis treatment:a prospective cohort study among tuberculosis patients in SouthEastern Amahra Region,Ethiopia显示文摘Background:There is growing evidence suggesting that diabetes mellitus(DM)affects disease presentation and treatment outcome in tuberculosis(TB)patients.This study aimed at investigating the role of DM on clinical presentations and treatment outcomes among newly diagnosed TB patients.Methods:A prospective cohort study was conducted in South-Eastern Amhara Region,Ethiopia from September 2013 till March 2015.Study subjects were consecutively recruited from 44 randomly selected health facilities in the study area.Participants were categorized into two patient groups,namely,patients with TB and DM(TBDM)and TB patients without DM(TBNDM).Findings on clinical presentations and treatment outcomes were compared between the two patient groups.Cox proportional hazard regression analysis was applied to identify factors associated with death.Results:Out of 1314 TB patients enrolled in the study,109(8.3%)had coexisting DM.TBDM comorbidity[adjusted hazard ratio(AHR)3.96;95%confidence interval(C.I.)(1.76–8.89)],and TB coinfection with human immunodeficiency virus(HIV)[AHR 2.59;95%C.I.(1.21–5.59)]were associated with increased death.TBDM and TBNDM patients did not show significant difference in clinical symptoms at baseline and during anti-TB treatment period.However,at the 2nd month of treatment,TBDM patients were more symptomatic compared to patients in the TBNDM group.Conclusions:The study showed that DM is associated with increased death during TB treatment.DM has no association with clinical presentation of TB except at the end of the intensive phase treatment.Routine screening of TB patients for DM is recommended for early diagnosis and treatment of patients with TBDM comorbidity. | Mahteme Haile Workneh Gunnar Aksel Bjune Solomon Abebe Yimer | 2016 | Infectious Diseases of Poverty2016，5，1： | 2 |
| 3 | Comparison of Prognostic Scores for Patients with Colorectal Cancer Peritoneal Metastases Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy显示文摘 | Peter H. Cashin Wilhelm Graf Peter Nygren Haile Mahteme | 2013 | Annals of Surgical Oncology2013，，： | 1 |
| 4 | Cytoreductive surgery and hyperthermic intra‐peritoneal chemotherapy treatment of colorectal peritoneal metastases: Cohort analysis of high volume disease and cure rate显示文摘 | Peter H Cashin Faoz Dranichnikov Haile Mahteme | 2014 | J. Surg. Oncol2014，，： | 1 |
| 5 | Septic Complications and Prognosis After Surgery for Rectal Cancer显示文摘 | Ulf Kressner M.D. Ph.D. Wilhelm Graf M.D. Ph.D. Haile Mahteme M.D. Ph.D. Lars P?hlman M.D. Ph.D. Bengt Glimelius M.D. Ph.D | 2002 | Diseases of the Colon & Rectum2002，，3： | 1 |
| 6 | Costs and clinical outcome of neoadjuvant systemic chemotherapy followed by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in peritoneal carcinomatosis from gastric cancer显示文摘 | Bo Hultman Jonas Lundkvist Bengt Glimelius Peter Nygren Haile Mahteme | 2012 | Acta Oncologica2012，，1： | 1 |
| 7 | Cytoreductive surgery and hyperthermic intra‐peritoneal chemotherapy treatment of colorectal peritoneal metastases: Cohort analysis of high volume disease and cure rate显示文摘 | Peter H Cashin Faoz Dranichnikov Haile Mahteme | 2014 | Oncol2014，，2： | 1 |
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