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| 1 | 血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂的使用与2019冠状病毒疾病检测阳性之间的关系显示文摘血管紧张素转换酶抑制剂(angiotensin-converting enzyme inhibitor,ACEI)和血管紧张素受体拮抗剂(angiotensin receptor blocker,ARB)在2019新型冠状病毒疾病(coronavirus disease 2019,COVID-19)全球大流行背景下的作用备受争议。此类药物是治疗一些慢性病的必须药物,有建议停止使用这些药物. | Mehta N KalraA Nowacki AS Anjewierden S Han Z Bhat p Rubio AEC Jacob M Procop GW Harrington S Milinovich A Svensson LG Jehi L Young JB Chung MK 周卫(译) 叶鹏(校) | 2020 | 中华高血压杂志2020,28,5: | 9 |
| 2 | Dietary and metabolomic determinants of relapse in ulcerative colitis patients: A pilot prospective cohort study显示文摘AIM To identify demographic, clinical, metabolomic, and lifestyle related predictors of relapse in adult ulcerative colitis(UC) patients.METHODS In this prospective pilot study, UC patients in clinical remission were recruited and followed-up at 12 mo to assess a clinical relapse, or not. At baseline information on demographic and clinical parameters was collected. Serum and urine samples were collected for analysis of metabolomic assays using a combined direct infusion/liquid chromatography tandem mass spectrometry and nuclear magnetic resolution spectroscopy. Stool samples were also collected to measure fecal calprotectin(FCP). Dietary assessment was performed using a validated self-administered food frequency questionnaire. RESULTS Twenty patients were included(mean age: 42.7 ± 14.8 years, females: 55%). Seven patients(35%) experienced a clinical relapse during the follow-up period. While 6 patients(66.7%) with normal body weight developed a clinical relapse, 1 UC patient(9.1%) who was overweight/obese relapsed during the follow-up(P = 0.02). At baseline, poultry intake was significantly higher in patients who were still in remission during follow-up(0.9 oz vs 0.2 oz, P = 0.002). Five patients(71.4%) with FCP > 150 μg/g and 2 patients(15.4%) with normal FCP(≤ 150 μg/g) at baseline relapsed during the follow-up(P = 0.02). Interestingly, baseline urinary and serum metabolomic profiling of UC patients with or without clinical relapse within 12 mo showed a significant difference. The most important metabolites that were responsible for this discrimination were trans-aconitate, cystine and acetamide in urine, and 3-hydroxybutyrate, acetoacetate and acetone in serum. CONCLUSION A combination of baseline dietary intake, fecal calprotectin, and metabolomic factors are associated with risk of UC clinical relapse within 12 mo. | Ammar Hassanzadeh Keshtel iFloris F van den Brand Karen L Madsen Rupasri Mandal Rosica ValchevaKaren I Kroeker Beomsoo Han Rhonda C Bell Janis Cole Thomas Hoevers David S Wishart Richard N Fedorak Levinus A Dieleman | 2017 | World Journal of Gastroenterology2017,23,21: | 9 |
| 3 | An efficient descriptor model for designing materials for solar cells显示文摘An efficient descriptor model for fast screening of potential materials for solar cell applications is presented.It works for both excitonic and non-excitonic solar cells materials,and in addition to the energy gap it includes the absorption spectrum(α(E))of the material.The charge transport properties of the explored materials are modelled using the characteristic diffusion length(Ld)determined for the respective family of compounds.The presented model surpasses the widely used Scharber model developed for bulk heterojunction solar cells.Using published experimental data,we show that the presented model is more accurate in predicting the achievable efficiencies.To model both excitonic and non-excitonic systems,two different sets of parameters are used to account for the different modes of operation.The analysis of the presented descriptor model clearly shows the benefit of includingα(E)and Ld in view of improved screening results. | Fahhad H Alharbi Sergey N Rashkeev Fedwa El-Mellouhi Hans P Lüthi Nouar Tabet Sabre Kais | 2015 | npj Computational Materials2015,,1: | 3 |
| 4 | Relationship between diabetes mellitus and cataract in Hungary显示文摘AIM:To examine the coexistence of diabetes mellitus(DM)and cataract in Hungary.The effects of DM on the cataract surgical results were also in the focus of analysis.METHODS:Statistical data analysis of the results of the Rapid Assessment of Avoidable Blindness with Diabetic Retinopathy(RAAB+DR)module conducted in Hungary in 2015.This cross-sectional,population-based,national survey included 3523 people aged 50 years and over.Participants of the survey were examined on-site.Visual acuity,main cause for visual impairment(using direct and indirect ophthalmoscopes),in case of best corrected visual acuity(BCVA)≤0.5 and blood glucose level(random test with glucometer)were examined.RESULTS:The prevalence of cataract was 23.4%,and DM was 20.0%.The occurrence of cataract steadily increased with age.Among the examined participants with DM,the prevalence of cataract was significantly(P=0.012)higher(+35%)than that in non-diabetic subjects(29.5%vs 21.8%).Following aging(OR=15.2%,P<0.001),DM proved to be the most independent influencing risk factor(OR=49.9%,P<0.001).The presence of DM was neither an influencing factor for complications of cataract surgery,nor for postoperative visual acuity.CONCLUSION:DM appears to be one of the main risk factors for developing cataract.Other risk factors,such as age,sex and environment also play an influencing role.Diabetes does not seem to affect the occurrence of cataract surgical complications. | Anita Pék Dorottya Szabó Gábor LászlóSándor Gábor Tóth András Papp Zoltán Zsolt Nagy Hans Limburg János Németh | 2020 | International Journal of Ophthalmology(English edition)2020,13,5: | 2 |
| 5 | Assessment of erosion haz- ard with the USLE and GIS A ease study of the Upper Ewaso Nglro North basin of Kenya显示文摘 | Bancy M Mati Royston P C Morgan Francis N Gichuki John N Quinton Tim R Brewer Hans P l iniger | 2000 | lnternation Journal of Applied Earth Ob- servation and Geoinformation2000,2,2: | 1 |
| 6 | Copper-binding ability of dissolved organic matter derived from anaerobically digested biosolids显示文摘 | Han N Thompson M L | 1999 | Journal of Environmental Quality1999,28,3: | 1 |
| 7 | Finite element analysis of Lamb wave propagation in a thin aluminum plate 显示文摘 | Han S J Palazotto A N Leakeas C L | 2009 | Journal of Aerospace Engineering2009,22,2: | 1 |
| 8 | 查看详情显示文摘 | Zhang J P Yang H P Han K L Deng W Q He G Z Lou N Q | | 0,,: | 1 |
| 9 | Neuroprotective effects of ginsen-oside Rd against oxygen - glucose deprivation in cultured hippocampalneurons显示文摘 | Ye R D Li N L Han J L | 2009 | Neuroscience Research2009,64,: | 1 |
| 10 | Research summarization on capsaicin显示文摘 | FengJ N Fu J Han M L | 2005 | Acta Agric Borea Sin2005,14,1: | 1 |
| 11 | Renal function as a predictor of outcome in a broad spectrum of patients with heart failure显示文摘 | HANS L HILLEG E DOROTHEA N | 2006 | Circulation2006,113,: | 1 |
| 12 | Color stability of compomer after immersion in various media 显示文摘 | ABU- BAKR N HAN L OKAMATO A | 2000 | J Esthet Dent2000,,12: | 1 |
| 13 | The Arabidopsis doublestranded RNA-binding protein HYL1 plays a role in microRNAmediated gene regulation显示文摘 | Han M H Goud S Song L Fedoroff N | 2004 | Proc Natl Acad Sci USA2004,101,4: | 1 |
| 14 | Proliferative and apoptotic effects of gastric epithelial cells induced by coceoid Helicobacter pylori 显示文摘 | Li N Han L Chen J | 2013 | J Basic Microbiol2013,53,: | 1 |
| 15 | Characterization of driving patterns and development of a driving cycle in a military area显示文摘 | Han D S Choi N W Cho S L | 2012 | Transportation Research Part D:Transport and Environment2012,17,7: | 1 |
| 16 | Compression Behavior of Stiff- ened Panel with a Clearly Visible Stiffener Impact Damage 显示文摘 | Suh S Han N L Yang J M | 2003 | Composite Structures2003,62,: | 1 |
| 17 | 显示文摘 | Do L Han E Yamamoto N | 1996 | Mol Cryst Liq Cryst1996,280,: | 1 |
| 18 | Modeling of an Equivalent Circuit forDye - Sensitized Solar Cells 显示文摘 | Han L Y Koide N Chiba Y | 2004 | Applied Physics Letter2004,84,: | 1 |
| 19 | ln vitro inhibitory effect of triterpenoidal saponinsfrompatycodiradixonpancreaticlipase 显示文摘 | Xu B J Han L K Zheng Y n | 2005 | Arch PharmRes2005,28,2: | 1 |
| 20 | Comparative analysis of imaging and pathology features of mucinous carcinoma of the breast显示文摘 | Zhang L Jia N Han L | 2015 | Clin Breast Cancer2015,15,2: | 1 |