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| 1 | New Lignans from the Leaves and Stems of Schisandra chinensis and Their Anti-HIV-1 Activities显示文摘Six new lignans(1-6),as well as five known ones(7-11)were isolated from the leaves and stems of Schisandra chinensis.The structures of 1-6 were established on the basis of spectroscopic methods including 1D-and 2D-NMR techniques and CD experiments.Compound 1 was the first example of naturally occurring N-containing lignans featuring a nicotinoyl group.All the new compounds were evaluated for their anti-HIV-1 activities and showed EC50 values in the range 17.89-138.23μg/mL. | Yiming Shi Weimao Zhong Huan Chen Ruirui Wang Shanzhai Shang Chengqin Liang Zhonghua Gao Yongtang Zheng Weilie Xiao Handong Sun | 2014 | Chinese Journal of Chemistry2014,32,8: | 3 |
| 2 | Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys显示文摘Four new diterpenoids, phyllostachysins I–L(1–4), along with a known one, hebeiabinin B(5), were isolated from the aerial parts of Isodon phyllostachys(I. phyllostachys). Compounds 1 and 2 feature an ent-kaurane backbone, and 3, 4 and 5 bear an ent-abietane skeleton. Their structures were elucidated by means of spectroscopic analysis. Compounds 3 and 4 exhibited significant cytotoxic activity against human tumor cell lines(HL-60, SMMC-7721, A-549, MCF-7 and SW-480), and strongly inhibited NO production in LPS-stimulated RAW264.7 cells. | Jin Yang Yaqi An Haiyan Wu Miao Liu Weiguang Wang Xue Du Yan Li Jianxin Pu Handong Sun | 2016 | Science China Chemistry2016,59,9: | 2 |
| 3 | Natural products against hematological malignancies and identification of their targets显示文摘Naturally occurring molecules derived from higher plants, animals, microorganisms and minerals play an important role in the discovery and development of novel therapeutic agents. The identification of molecular targets is of interest to elucidate the mode of action of these compounds, and it may be employed to set up target-based assays and allow structure-activity relationship studies to guide medicinal chemistry efforts toward lead optimization. In recent years, plant-derived natural compounds possessing potential anti-tumor activities have been garnering much interest and efforts are underway to identify their molecular targets. Here, we attempt to summarize the discoveries of several natural compounds with activities against hematological malignancies, such as adenanthin, oridonin, gambogic acid and wogonoside, the identification of their targets, and their modes of actions. | XU Ying LIU JinBao WU YingLi GUO QingLong SUN HanDong CHEN GuoQiang | 2015 | Science China(Life Sciences)2015,58,12: | 2 |
| 4 | Waveguide design and application with transformation optics显示文摘Waveguide design becomes more and more important with the increasing demand of efcient routing and interconnection of electromagnetic signals for advanced information technologies.Here we review the basic theory,special techniques,and potential applications of transformation optics in waveguide design.Three major design strategies of transformation optics and their limitations in waveguide applications are discussed.The recent new trends of transformation techniques by imposing specifc restrictions from materials are emphasized for practical implementation.Plasmonic waveguide is used as an example to compare these transformation strategies.Applications beyond waveguides but with great practical value such as super-resolution hyperlens design are also discussed in the context of waveguiding phenomena from the perspective of transformation optics. | XU HongYi SUN HanDong ZHANG BaiLe | 2013 | Science China(Information Sciences)2013,56,12: | 2 |
| 5 | Improving flesh quality of grass carp(Ctenopharyngodon idellus)by completely replacing dietary soybean meal with yellow mealworm(Tenebrio molitor)显示文摘In order to find viable alternative protein sources for aquaculture,we evaluated the effect of partial or complete replacement of dietary soybean meal with yellow mealworm(TM)on the flesh quality of grass carp.In this study,180 grass carp(511.85±0.25 g)were fed 3 experimental diets in which 0%(CN),30%(YM30)and 100%(YM100)dietary soybean meal was replaced by TM for 90 d.The results showed that growth performance,biological parameters and serum antioxidant capacity of grass carp were not affected by dietary TM(P>0.05).Both muscle and whole body crude protein were obviously promoted with the increase of dietary TM(P<0.05),and the concentration of heavy metal in muscle was not influenced(P>0.05),indicating that food safety was not influenced by TM.Dietary TM improved muscle textural characteristics by elevating adhesiveness,springiness and chewiness in YM100(P<0.05).In addition,the muscle tenderness was significantly increased by declining the shear force(P<0.05).The muscle fiber density in YM30&YM100 and length of dark bands and sarcomeres in YM100 were obviously increased(P<0.05).The expression of myf5,myog and myhc exhibited a significant upward trend with the increase of dietary TM(P<0.05),which promoted fiber density,length of sarcomere and texture of grass carp muscle.According to the results of metabolomics,the arachidonate(ARA)and eicosapentaenoic acid(EPA)were notably elevated in YM30 and YM100,which indicated that the improvement of flesh quality of grass carp may contribute to the dietary TM influence on muscle lipid metabolism,especially the polyunsaturated fatty acids.In conclusion,TM can completely replace dietary soybean meal and improve the nutritional value of grass carp. | Handong Li Rongrong Xue Jian Sun Hong Ji | 2023 | Animal Nutrition2023,,1: | 2 |
| 6 | Hydration of high-volume fly ash cement pastes显示文摘 | Zhang Yamei Sun Wei Yan Handong | 2000 | Cement and Concrete Composites2000,30,6: | 1 |
| 7 | Antioxidant properties of two gallotannins isolated from the leaves of Pistacia weinmannifolia 显示文摘 | Xingyu Zhao Handong Sun Aijun Hou | 2005 | Biochimica et Biophysica Acta2005,1725,: | 1 |
| 8 | Hydration of hish-volume fly ash cement pastes显示文摘 | Yamei Zhang Wei Sun Handong Yan | 2000 | Cement & Concrete Composites2000,22,6: | 1 |
| 9 | Analysis of Mechanism on Water-reducing Effect of Fine Ground Slag, High-calcium Fly Ash, and Low-calcium Fly Ash显示文摘 | Sun Wei Yan Handong Zhan Binggen | 2003 | Cement and Concrete Research2003,33,: | 1 |
| 10 | The effect of silica fume and steel fiber on the dynamit performance of high-strenth concrte显示文摘 | Yan Handong Sun Wei Chen Huisu | 1999 | Cement and Concrete Research1999,29,3: | 1 |
| 11 | Effect of total phenolics from Laggera alata on acute and chronic inflammation models显示文摘 | Yihang Wu Changxin Zhou Liyan Song Xiangping Li Shuyun Shi Jianxia Mo Haiyong Chen Hua Bai Xiumei Wu Jun Zhao Rongping Zhang Xiaojiang Hao Handong Sun Yu Zhao | 2006 | Journal of Ethnopharmacology2006,,2: | 1 |
| 12 | Cytotoxjc antitumor activities of rabdosia diterpencids显示文摘 | Fujita Tetsuro Takeda Ycsbio Sun Handong | 1988 | Planta Med1988,,: | 1 |
| 13 | Significant enhancement of UV emission in ZnO nanorods subject to Ga+ ion beam irradiation显示文摘在光电子的 ZnO nanomaterials 的应用仍然由于他们的不够的光致发光效率被限制。以便优化 ZnO nanorods 的光致发光性质,在与在不同离子精力(0.5 keV16 keV ) 的 Ga + 离子照耀的关联,在 Si 底层上种的垂直地排列的 ZnO nanorods 的紫外排放在现在的学习被调查。我们发现紫外紧张与增加 Ga + 离子精力很快增加了,直到它在 2 keV,在点,紧张比由成长得当的 ZnO nanorods 生产了那高约 50 倍附近的最大值。低精力的 Ga + 离子的轻轻的轰炸把缺点从 ZnO nanorod 表面移开。在另一方面, Ga + 离子植入进 nanorods,导致压缩紧张。在表面缺点和压缩紧张的介绍的移动之上的水晶格子的完美的安排是贡献紫外轻产生的重要改进的二个因素,这被相信。 | Boluo Yadian Rui Chen Hai Liu Handong Sun Qing Liu Chee Lip Gan Zhou Kun Chunwang Zhao Bin Zhu Yizhong Huang | 2015 | Nano Research2015,8,6: | 1 |
| 14 | The efect of silica fume and steel fiber on the dynamic mechanical performance of high-strength concrete显示文摘 | Handong Yan Wei Sun Huisu Chen | 1999 | Cement and Concrete Research1999,29,3: | 1 |
| 15 | Phytechomistry显示文摘 | Chen Yiping Lin Zhongwen Zhang Hongjie and Sun Handong | 1990 | Print in Great Brain1990,29,10: | 1 |
| 16 | Hydration of High-volume Fly Ash Cement Pastes显示文摘 | Zhang Yamei Sun Wei Yan Handong | 2000 | Cement and Concrete Composites2000,30,6: | 1 |
| 17 | The effect of silica fume and steel fiber on the dynamic mechanical performance of high-strergth concrete显示文摘 | Handong Yan Wei Sun and Huisu Chen | 1999 | Cement and Concrete Research1999,29,3: | 1 |
| 18 | 显示文摘 | Zhang Yamei Sun Wei Yan Handong | 2000 | Cement and Concrete Composites2000,30,6: | 1 |
| 19 | The method to increase the emissivity of high temperature infrared radiation coating显示文摘 | SUN Handong FAN Zhen CHANG Dading | 1990 | Infrared Technology1990,12,3: | 1 |
| 20 | The effect of silica fume and steel fiber on the dynamic mechanical performance of high-strength concrete显示文摘 | Handong Yan Wei Sun and Huisu Chen | 1999 | Cement and Concrete Research1999,29,3: | 1 |