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您的检索式：作者名="Hanli Ruan"
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| 1 | Antihyperglycemic activity of kinsenoside, a high yielding constituent from Anoectochilus roxburghii in streptozotocin diabetic rats显示文摘 | Yonghui Zhang Jinyan Cai Hanli Ruan Huifang Pi Jizhou Wu | 2007 | Journal of Ethnopharmacology2007，，： | 1 |
| 2 | Ergochaeglobosins A—E, Unprecedented Heterodimers of Cytochalasan and Ergosterol from Chaeglobosin globosum P2-2-2显示文摘Five novel heterodimers of cytochalasan and ergosterol,ergochaeglobosins A—E,were isolated from an endophytic fungus Chaetomium globosum P2-2-2.Ergochaeglobosin A(1) possesses an unprecedented 5/6/13/6/5/6/6/6 fused octacyclic ring system,and ergochaeglobosins B(2) and C(3) form a unique 5/6/13/6/6/6/6/5 fused octacyclic ring system,whereas ergochaeglobosins D(4) and F(5) are the first cytochalasan heterodimers formed via a N-1′/C-3′′single bond.Their structures with absolute configurations were established by extensive spectroscopic analyses,single-crystal X-ray diffraction,and ECD calculations.The plausible biogenetic pathway of 1—5 was postulated.Compound 1 exhibited inhibitory effects against ConA-induced T cells and LPS-induced B cells proliferation with IC50 values of 19.2 and 14.1μmol/L,respectively.Co-treatment of 3(20μmol/L)with TRAIL(150 ng/mL)could significantly decrease the cell viability of A549 by 24.9%comparing with monotherapy of 3(20μmol/L). | Xiaogang Peng Junjun Liu Chunlun Qin Qian Wu Wanpeng Li Fatemeh Mohammadipanah Hanli Ruan | 2022 | Chinese Journal of Chemistry2022，40，16： | 0 |
| 3 | Thiocytochalasins A−D,four sulfur-containing cytochalasans from an endophytic fungus Phoma multirostrata XJ-2-1显示文摘Four unprecedented sulfur-containing cytochalasans,thiocytochalasins A−D(1−4),were isolated from an endophytic fungus Phoma multirostrata XJ-2-1.Thiocytochalasins A(1)and B(2)feature a novel 5/6/14/5 tetracyclic scaffold,which are the first examples of cytochalasan containing a thiophene moiety.Thiocytochalasins C(3)and D(4)are epimeric cytochalasan homodimers formed via a thioether bridge.Their structures with absolute configurations were established by detailed analysis of the HRESIMS,NMR,and X-ray crystallography.The plausible biogenetic pathway of 1−4 was postulated.Compounds 3 and 4 exhibited significant cytotoxicity against CT26 cells with IC_(50) values of 0.85 and 0.76µmol/L,respectively. | Xiaogang Peng Jinling Chang Ying Gao Fangfang Duan Hanli Ruan | 2022 | Chinese Chemical Letters2022，33，10： | 0 |
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