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| 1 | Near-diffraction-limited linearly polarized narrow-linewidth random fiber laser with record kilowatt output显示文摘In this paper, we propose and experimentally investigate a linearly polarized narrow-linewidth random fiber laser(RFL) operating at 1080 nm and boost the output power to kilowatt level with near-diffraction-limited beam quality using a master oscillation power amplifier. The RFL based on a half-opened cavity, which is composed of a linearly polarized narrow-linewidth fiber Bragg grating and a 500 m piece of polarization-maintained Ge-doped fiber, generates a 0.71 W seed laser with an 88 pm full width at half-maximum(FWHM) linewidth and a 22.5 dB polarization extinction ratio(PER) for power scaling. A two-stage fiber amplifier enhances the seed laser to the maximal 1.01 k W with a PER value of 17 dB and a beam quality of M_x^2=1.15 and M_y^2=1.13. No stimulated Brillouin scattering effect is observed at the ultimate power level, and the FWHM linewidth of the amplified random laser broadens linearly as a function of the output power with a coefficient of about 0.1237 pm∕W.To the best of our knowledge, this is the first demonstration of a linearly polarized narrow-linewidth RFL with even kilowatt-level near-diffraction-limited output, and further performance scaling is ongoing. | JIANGMING XU LONG HUANG MAN JIANG JUN YE PENGFEI MA JINYONG LENG JIAN WU HANWEI ZHANG PU ZHOU | 2017 | Photonics Research2017，5，4： | 20 |
| 2 | Emerging systemic delivery strategies of oncolytic viruses:A key step toward cancer immunotherapy显示文摘Oncolytic virotherapy(OVT)is a novel type of immunotherapy that induces anti-tumor responses through selective self-replication within cancer cells and oncolytic virus(OV)-mediated immunostimulation.Notably,talimogene laherparepvec(T-Vec)developed by the Amgen company in 2015,is the first FDA-approved OV product to be administered via intratumoral injection and has been the most successful OVT treatment.However,the systemic administration of OVs still faces huge challenges,including in vivo pre-existing neutralizing antibodies and poor targeting delivery efficacy.Recently,state-of-the-art progress has been made in the development of systemic delivery of OVs,which demonstrates a promising step toward broadening the scope of cancer immunotherapy and improving the clinical efficacy of OV delivery.Herein,this review describes the general characteristics of OVs,focusing on the action mechanisms of OVs as well as the advantages and disadvantages of OVT.The emerging multiple systemic administration approaches of OVs are summarized in the past five years.In addition,the combination treatments between OVT and traditional therapies(chemotherapy,thermotherapy,immunotherapy,and radiotherapy,etc.)are highlighted.Last but not least,the future prospects and challenges of OVT are also discussed,with the aim of facilitating medical researchers to extensively apply the OVT in the cancer therapy. | Weiyue Ban Jianhuan Guan Hanwei Huang Zhonggui He Mengchi Sun Funan Liu Jin Sun | 2022 | Nano Research2022，15，5： | 2 |
| 3 | Energy recovery in China from solid wastes by the moving grate and circulating fluidized bed technologies显示文摘In recent years,the Chinese waste-to-energy(WTE)industry is growing at the rate of about thirty new plants each year.The municipal solid waste(MSW)fuel has a low heating value of 4-7 MJ/kg,in comparison to about 11 MJ/kg in U.S.and 8-11 MJ/kg in EU.Combustion of the low heating value fuel on a moving grate(MG),the dominant combustion technology worldwide,is difficult to control and measures have to be taken to remove some moisture prior to combustion.For this and other reasons,an alternative technology,the circulating fluid bed(CFB)has been implemented in China.This paper is a comparative study of the two technologies and was carried out by Columbia University and two senior engineers,representing the MG and CFB technologies of China.Data were derived from industrial operating plants and from the literature.The fuel to MG furnaces is as-received MSW,while the MSW to CFB reactors is pre-shredded using high-torque low-speed shredders.The availability of MG plants,over a 1-year period,is 90%+,while that of CFB facilities is 80%+.Also,the in-plant electricity consumption of MG plants is slightly lower than the consumption of CFB plants.The MG furnace is less compact,than that of a CFB combustion chamber,with a heat flux range from 0.5 to 0.6 MW/m^(2) of grate surface area,while that of CFB furnace was about 1.7 MW/m^(2) of furnace cross-section.The bottom ash in a MG process is typically wet-discharged and the recovery of metals is less efficient.A drawback of the CFB process is that the fly ash generated is 5-10%of the weight of MSW combusted,as compared to 1-3%for moving grate plants in China. | A.C.Bourtsalas Qunxing Huang Hanwei Zhang Nickolas J.Themelis | 2020 | Waste Disposal and Sustainable Energy2020，2，1： | 1 |
| 4 | Synthesis and Properties of Novel Epoxidized Soybean Oil-modified Phenolic Resin /Montmorillonite Nanocomposites显示文摘The novel epoxidized soybean oil-modified-phenolic resin/clay nanocomposites(ESO-M-PR/CN) was prepared. The coupling agent-benzyldimethylphenylammonium chloride [C6H5CH2N+(CH3)2C6H5Cl-,B2MP] was adopted to modify the interface between the organic and inorganic phases. The effect of the nanocomposite structure on its physical and chemical properties was discussed. During the synthesizing process of ESO-M-PR/CN, the phenol hydroxyl was etherified by ESO or ESO epoxy resin prepolymer to provide long ESO epoxy segments. Long ESO epoxy resin chain segments enhanced the crosslink density of ESO-M-PR/CN. The thermal and mechanical properties exhibit a significant improvement. The temperature at which a weight loss of 5% occurs increases from 287.1 ℃ to 402.3 ℃. The flexural strength increases by 25%, while the flexural modulus increases by 39%. Moreover, the properties of resin were enhanced by the effect of the inorganic nanoparticles, while the size of the nanomontmorillonites in the phenolic resin was characterized with a scanning electron microscope. The particle size of inorganic montmorillonites in the modifi ed system is less than 100 nm. | HU Jianfeng SITU Yue XU Li HUANG Hong FU Heqing ZENG Hanwei CHEN Huanqin | 2008 | Journal of Wuhan University of Technology(Materials Science)2008，23，4： | 1 |
| 5 | Broad-spectrum and powerful neutralization of bacterial toxins by erythroliposomes with the help of macrophage uptake and degradation显示文摘Anti virulence strategy has been considered as one of the most promising approaches to combat drug-rcesistant bacterial infections.Porc-forming toxins(PFTs)are the largest class of bacterial toxins,inficting their virulence ffect through creating pores on the cell membrane.However,curent solutions for eliminating PFTs are mostly designed based on their molecular structure,requiring customized design for different interactions.In the present study,we employed erythroliposome(denoted as RM-PL),a biomimetic platform constructed by artificial lipid membranes and natural erythrocyle membranes,to necutralize different hemolytic PFTs regardless of their molecular structure.When tested with model PFTs,including a-hemolysin,listeriolysin O,and streptolysin O,RM-PL could completely inhibit toxin-induced hemolysis in a concentration-dependent manner.In vivo studies further confirmed that RM-PL.could eficiently neuralize various toxins and save animals'lives without causing damage to 0rgans or tissues.In addition,we explored the underlying mechanisms of this efficient detoxification ability and found that it was mainly macrophages in the spleen and the liver that took up RM-PL-absorbed toxins through a variety of endocytosis pathways and digested them in lysosomes.In summary,the biomimetic RM-PL presented a promising system for broad-spectrum and powerful toxin neutralization with a mech-anism of lysosome-mediaed loxin degradation. | Chunying Liu Shuangrong Ruan Ying He Xuejing Li Yuefei Zhu Honglan Wang Hanwei Huang Zhiqing Pang | 2022 | Acta Pharmaceutica Sinica B2022，12，11： | 1 |
| 6 | Population structure and association mapping on chromosome 7 using a diverse panel of Chinese germplasm of rice ( Oryza sativa L.)显示文摘 | Weiwei Wen Hanwei Mei Fangjun Feng Sibin Yu Zhicheng Huang Jinhong Wu Liang Chen Xiaoyan Xu Lijun Luo | 2009 | Theoretical and Applied Genetics2009，，3： | 1 |
| 7 | Research on tension control model for traction and take-up system of loom显示文摘 | WANG Youzhao HUANG Jing CHEN Hanwei | 2013 | Advanced Materials Research2013，627，： | 1 |
| 8 | Light-emitting devices based on atomically thin MoSe_(2)显示文摘Atomically thin MoSe_(2) layers,as a core member of the transition metal dichalcogenides(TMDs)family,benefit from their appealing properties,including tunable band gaps,high exciton binding energies,and giant oscillator strengths,thus pro-viding an intriguing platform for optoelectronic applications of light-emitting diodes(LEDs),field-effect transistors(FETs),sin-gle-photon emitters(SPEs),and coherent light sources(CLSs).Moreover,these MoSe_(2) layers can realize strong excitonic emis-sion in the near-infrared wavelengths,which can be combined with the silicon-based integration technologies and further encourage the development of the new generation technologies of on-chip optical interconnection,quantum computing,and quantum information processing.Herein,we overview the state-of-the-art applications of light-emitting devices based on two-dimensional MoSe_(2) layers.Firstly,we introduce recent developments in excitonic emission features from atomically thin MoSe_(2) and their dependences on typical physical fields.Next,we focus on the exciton-polaritons and plasmon-exciton polaritons in MoSe_(2) coupled to the diverse forms of optical microcavities.Then,we highlight the promising applications of LEDs,SPEs,and CLSs based on MoSe_(2) and their heterostructures.Finally,we summarize the challenges and opportunities for high-quality emis-sion of MoSe_(2) and high-performance light-emitting devices. | Xinyu Zhang Xuewen Zhang Hanwei Hu Vanessa Li Zhang Weidong Xiao Guangchao Shi Jingyuan Qiao Nan Huang Ting Yu Jingzhi Shang | 2024 | Journal of Semiconductors2024，45，4： | 0 |
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