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| 1 | Effects of composition and granulometry on thermal conductivity of anode cover materials显示文摘 | Hasini Wijayaratne Margaret Hyland Mark Taylor | | 0,,: | 1 |
| 2 | Beta amyloid effects on expression of multidrug efflux transporters in brain endothelial cells 显示文摘 | KATARZYNA D K HASINI C W STEPHEN B H | 2011 | Brain Res2011,1418,18: | 1 |
| 3 | Maciopoious poly (3- hydroxybu-tyiate-co-3-Hydroxyvaletate) matrices for bone tissue engineering 显示文摘 | Kose GT Kenar H Hasini N | 2003 | Biomaterials2003,24,3: | 1 |
| 4 | 射孔密度分布对水平井生产动态的影响显示文摘针对水平井产量受水平井井筒射孔密度分布影响的问题,建立两种水平井射孔密度分布模式(即分别增大井筒入口段和出口段射孔密度)下的数值模型对水平井两相流动进行模拟;将模拟结果与实验结果进行对比,验证本研究数值模拟方法的可靠性,在此基础上采用数值模拟研究两种射孔密度分布模式下井筒各流型阶段总压降、气水两相流体表观速度、空隙率、液膜厚度和产气量、产液量的变化规律。研究表明,当水相流量保持不变时,随着空气流量的增加,总压降、气水两相流体表观速度增大,空隙率增加,液膜厚度减小;相较于增大出口段射孔密度,当入口段射孔密度增大时,产液量和产气量均增加,且产气量随着气体流量增加而增大;产液量在泡状流阶段增加,而达到弹状流—分层流过渡点后开始降低,进入分层波状流阶段后产液量开始增加;无因次产液量在增大井筒入口段射孔密度的模式下更大,且随着径向气相流量的增加而增大。 | KAREEM Hasanain J HASINI Hasril ABDULWAHID Mohammed A | 2024 | 石油勘探与开发2024,51,2: | 0 |
| 5 | Targeting multiple signaling pathways:the new approach to acute myeloid leukemia therapy显示文摘Acute myeloid leukemia(AML)is the most common form of acute leukemia in adults and the second most common form of acute leukemia in children.Despite this,very little improvement in survival rates has been achieved over the past few decades.This is partially due to the heterogeneity of AML and the need for more targeted therapeutics than the traditional cytotoxic chemotherapies that have been a mainstay in therapy for the past 50 years.In the past 20 years,research has been diversifying the approach to treating AML by investigating molecular pathways uniquely relevant to AML cell proliferation and survival.Here we review the development of novel therapeutics in targeting apoptosis,receptor tyrosine kinase(RTK)signaling,hedgehog(HH)pathway,mitochondrial function,DNA repair,and c-Myc signaling.There has been an impressive effort into better understanding the diversity of AML cell characteristics and here we highlight important preclinical studies that have supported therapeutic development and continue to promote new ways to target AML cells.In addition,we describe clinical investigations that have led to FDA approval of new targeted AML therapies and ongoing clinical trials of novel therapies targeting AML survival pathways.We also describe the complexity of targeting leukemia stem cells(LSCs)as an approach to addressing relapse and remission in AML and targetable pathways that are unique to LSC survival.This comprehensive review details what we currently understand about the signaling pathways that support AML cell survival and the exceptional ways in which we disrupt them. | Jenna L.Carter Katie Hege Jay Yang Hasini A.Kalpage Yongwei Su Holly Edwards Maik Hüttemann Jeffrey W.Taub Yubin Ge | 2020 | Signal Transduction and Targeted Therapy2020,5,1: | 0 |
| 6 | Fungal diversity notes 491–602: taxonomic and phylogenetic contributions to fungal taxa显示文摘This is a continuity of a series of taxonomic and phylogenetic papers on the fungi where materials were collected from many countries,examined and described.In addition to extensive morphological descriptions and appropriate asexual and sexual connections,DNA sequence data are also analysed from concatenated datasets to infer phylogenetic relationships and substantiate systematic positions of taxa within appropriate ranks.Wherever new species or combinations are proposed,we apply an integrative approach using morphological and molecular data as well as ecological features wherever applicable.Notes on 112 fungal taxa are compiled in this paper including Biatriosporaceae and Roussoellaceae,Didysimulans gen.nov.,81 new species,18 new host records and new country records,five reference specimens,two new combinations,and three sexual and asexual morph reports.The new species are Amanita cornelii,A.emodotrygon,Angustimassarina alni,A.arezzoensis,A.italica,A.lonicerae,A.premilcurensis,Ascochyta italica,A.rosae,Austroboletus appendiculatus,Barriopsis thailandica,Berkleasmium ariense,Calophoma petasitis,Camarosporium laburnicola,C.moricola,C.grisea,C.ossea,C.paraincrustata,Colletotrichum sambucicola,Coprinopsis cerkezii,Cytospora gelida,Dacrymyces chiangraiensis,Didysimulans italica,D.mezzanensis,Entodesmium italica,Entoloma magnum,Evlachovaea indica,Exophiala italica,Favolus gracilisporus,Femsjonia monospora,Fomitopsis flabellata,F.roseoalba,Gongronella brasiliensis,Helvella crispoides,Hermatomyces chiangmaiensis,H.chromolaenae,Hysterium centramurum,Inflatispora caryotae,Inocybe brunneosquamulosa,I.luteobrunnea,I.rubrobrunnea,Keissleriella cirsii,Lepiota cylindrocystidia,L.flavocarpa,L.maerimensis,Lophiotrema guttulata,Marasmius luculentus,Morenoina calamicola,Moelleriella thanathonensis,Mucor stercorarius,Myrmecridium fluviae,Myrothecium septentrionale,Neosetophoma garethjonesii,Nigrograna cangshanensis,Nodulosphaeria guttulatum,N.multiseptata,N.sambuci,Panus subfasciatus,Paraleptosphaeria padi,Paraphaeosphaeria viciae,Parathyridaria robiniae,Penicillium punicae,Phaeosphaeria calamicola,Phaeosphaeriopsis yuccae,Pleurophoma italica,Polyporus brevibasidiosus,P.koreanus,P.orientivarius,P.parvovarius,P.subdictyopus,P.ulleungus,Pseudoasteromassaria spadicea,Rosellinia mearnsii,Rubroboletus demonensis,Russula yanheensis,Sigarispora muriformis,Sillia italica,Stagonosporopsis ailanthicola,Strobilomyces longistipitatus,Subplenodomus galicola and Wolfiporia pseudococos.The new combinations are Melanomma populina and Rubroboletus eastwoodiae.The reference specimens are Cookeina tricholoma,Gnomoniopsis sanguisorbae,Helvella costifera,Polythrincium trifolii and Russula virescens.The new host records and country records are Ascochyta medicaginicola,Boletellus emodensis,Cyptotrama asprata,Cytospora ceratosperma,Favolaschia auriscalpium,F.manipularis,Hysterobrevium mori,Lentinus sajor-caju,L.squarrosulus,L.velutinus,Leucocoprinus cretaceus,Lophiotrema vagabundum,Nothophoma quercina,Platystomum rosae,Pseudodidymosphaeria phlei,Tremella fuciformis,Truncatella spartii and Vaginatispora appendiculata and three sexual and asexual morphs are Aposphaeria corallinolutea, Dothiorabuxi and Hypocrella calendulina. | Saowaluck Tibpromma Kevin D.Hyde Rajesh Jeewon Sajeewa S.N.Maharachchikumbura Jian-Kui Liu D.Jayarama Bhat E.B.Gareth Jones Eric H.C.McKenzie Erio Camporesi Timur S.Bulgakov Mingkwan Doilom AndreLuiz Cabral Monteiro de Azevedo Santiago Kanad Das Patinjareveettil Manimohan Tatiana B.Gibertoni Young Woon Lim Anusha Hasini Ekanayaka Benjarong Thongbai Hyang Burm Lee Jun-Bo Yang Paul M.Kirk Phongeun Sysouphanthong Sanjay K.Singh Saranyaphat Boonmee Wei Dong K.N.Anil Raj K.P.Deepna Latha Rungtiwa Phookamsak Chayanard Phukhamsakda Sirinapa Konta Subashini C.Jayasiri Chada Norphanphoun Danushka S.Tennakoon Junfu Li Monika C.Dayarathne Rekhani H.Perera Yuanpin Xiao Dhanushka N.Wanasinghe Indunil C.Senanayake Ishani D.Goonasekara N.Ide Silva Ausana Mapook Ruvishika S.Jayawardena Asha J.Dissanayake Ishara S.Manawasinghe K.W.Thilini Chethana Zong-Long Luo Kalani Kanchana Hapuarachchi Abhishek Baghela Adriene Mayra Soares Alfredo Vizzini Angelina Meiras-Ottoni Armin Mesic Arun Kumar Dutta Carlos Alberto Fragoso de Souza Christian Richter Chuan-Gen Lin Debasis Chakrabarty Dinushani A.Daranagama Diogo Xavier Lima Dyutiparna Chakraborty Enrico Ercole Fang Wu Giampaolo Simonini Gianrico Vasquez Gladstone Alves da Silva Helio Longoni Plautz Jr Hiran A.Ariyawansa Hyun Lee Ivana Kusan Jie Song Jingzu Sun Joydeep Karmakar Kaifeng Hu Kamal C.Semwal Kasun M.Thambugala Kerstin Voigt Krishnendu Acharya Kunhiraman C.Rajeshkumar Leif Ryvarden Margita Jadan MdIqbal Hosen Michal Miksık Milan C.Samarakoon Nalin N.Wijayawardene Nam Kyu Kim Neven Matocec Paras Nath Singh Qing Tian R.P.Bhatt Rafael JoseVilela de Oliveira Rodham E.Tulloss S.Aamir Saithong Kaewchai Sayali D.Marathe Sehroon Khan Sinang Hongsanan Sinchan Adhikari Tahir Mehmood Tapas Kumar Bandyopadhyay Tatyana YuSvetasheva Thi Thuong Thuong Nguyen Vladimır Antonın Wen-Jing Li Yong Wang Yuvraj Indoliya Zdenko Tkalcec Abdallah M.Elgorban Ali H.Bahkali Alvin M.C.Tang Hong-Yan Su Huang Zhang Itthayakorn Promputtha Jennifer Luangsa-ard Jianchu Xu Jiye Yan Kang Ji-Chuan Marc Stadler Peter E.Mortimer Putarak Chomnunti Qi Zhao Alan J.L.Phillips Sureeporn Nontachaiyapoom Ting-Chi Wen Samantha C.Karunarathna | 2017 | Fungal Diversity2017,,2: | 0 |
| 7 | Grappling with COVID-19 by imposing and lifting nonpharmaceutical interventions in Sri Lanka: A modeling perspective显示文摘The imposition and lifting of non-pharmaceutical interventions(NPIs)to avert the COVID-19 pandemic have gained popularity worldwide and will continue to be enforced until herd immunity is achieved.We developed a linear regression model to ascertain the nexus between the time-varying reproduction number averaged over a time window of six days(R_(ts))and seven NPIs:contact tracing,quarantine efforts,social distancing and health checks,hand hygiene,wearing of facemasks,lockdown and isolation,and health-related supports.Our analysis suggests that the second wave that emerged in Sri Lanka in early October 2020 continued despite numerous NPIs.The model indicates that the most effective single NPI was lockdown and isolation.Conversely,the least effective individual NPIs were hand hygiene and wearing of facemasks.The model also demonstrates that to mitigate the second wave to a satisfactory level(R_(ts)<1),the best single NPI was the contact tracing with stringent imposition(%of improvement of R_(ts) was 69.43 against the base case).By contrast,the best combination of two NPIs was the lockdown&isolation with health-related supports(%of improvement was 31.92 against the base case).As such,many health authorities worldwide can use this model to successfully strategize the imposition and lifting of NPIs for averting the COVID-19 pandemic. | Mahesh Jayaweera Chamath Dannangoda Dilum Dilshan Janith Dissanayake Hasini Perera Jagath Manatunge Buddhika Gunawardana | 2021 | Infectious Disease Modelling2021,6,1: | 0 |
| 8 | Gastrointestinal bleeding in a patient with a continuous-flow biventricular assist device显示文摘The association between continuous-flow left ventricular assist devices(CF-LVADs)and gastrointestinal(GI)bleeding from angiodysplasia is well recognized.However,the association between continuous-flow biventricular assist devices(CF-BIVADs)and bleeding angiodysplasia is less understood.We report a case of GI bleeding from a patient with a CF-BIVAD.The location of GI bleeding was identified by nuclear red blood cell bleeding scan.The vascular malformation leading to the bleed was identified and localized on angiography and then by pathology.The intensity of bleeding,reflected by number of units of packed red blood cells needed for normalization of hemoglobin,as well as the time to onset of bleeding after transplantation,are similar to that seen in the literature for CF-LVADs and pulsatile BIVADs.While angiography only detected a dilated late draining vein,pathology demonstrated the presence of both arterial and venous dilation in the submucosa,vascular abnormalities characteristic of a late arteriovenous malformation. | Raymond V Mirasol Jason J Tholany Hasini Reddy Billie S Fyfe-Kirschner Christina L Cheng Issam F Moubarak John L Nosher | 2016 | World Journal of Radiology2016,8,4: | 0 |
| 9 | Targeting multiple signaling pathways:the new approach to acute myeloid leukemia therapy显示文摘Acute myeloid leukemia(AML)is the most common form of acute leukemia in adults and the second most common form of acute leukemia in children.Despite this,very little improvement in survival rates has been achieved over the past few decades.This is partially due to the heterogeneity of AML and the need for more targeted therapeutics than the traditional cytotoxic chemotherapies that have been a mainstay in therapy for the past 50 years.In the past 20 years,research has been diversifying the approach to treating AML by investigating molecular pathways uniquely relevant to AML cell proliferation and survival.Here we review the development of novel therapeutics in targeting apoptosis,receptor tyrosine kinase(RTK)signaling,hedgehog(HH)pathway,mitochondrial function,DNA repair,and c-Myc signaling.There has been an impressive effort into better understanding the diversity of AML cell characteristics and here we highlight important preclinical studies that have supported therapeutic development and continue to promote new ways to target AML cells.In addition,we describe clinical investigations that have led to FDA approval of new targeted AML therapies and ongoing clinical trials of novel therapies targeting AML survival pathways.We also describe the complexity of targeting leukemia stem cells(LSCs)as an approach to addressing relapse and remission in AML and targetable pathways that are unique to LSC survival.This comprehensive review details what we currently understand about the signaling pathways that support AML cell survival and the exceptional ways in which we disrupt them. | Jenna LCarter Katie Hege Jay Yang Hasini AKalpage Yongwei Su Holly Edwards Maik Hüttemann Jeffrey WTaub Yubin Ge | 2021 | Signal Transduction and Targeted Therapy2021,6,1: | 0 |
| 10 | Book reviews显示文摘Rating system Exceptional/brilliant Excellent Good Has merit Not worth reading Acanthamoeba:Biology and Pathogenesis(2nd edition)By Naveed Ahmed Khan The American Phytopathological Society Hardcover;334 pages;including 88 figures and 26 tables;ISBN:978-1-908230-50-8(hardcover)ISBN:978-1-908230-51-5(eBook)Acanthamoeba is an opportunistic protist pathogen,causing a blinding keratitis and fatal granulomatous encephalitis.Thus Acanthamoeba has gained increasing attention during the last few decades from the scientific communities,with cellular microbiology,environmental biology,physiology,cellular interactions,molecular biology,biochemistry and the evolutionary studies. | Dhanushka N.Wanasinghe Sutakorn Kamolhan Dinushani Anupama Daranagama W.K.M.C.Dayarathne Asha J.Dissanayake Ishani D.Goonasekara K.K.Hapuarachchi Nimali Indiwaree de Silva Hasini Ekanayaka Subashini C.Jayasiri Samantha C.Karunarathna Rekhani H.Perera Chayanard Phukhamsakda Indunil C.Senanayake Qiuju Shang Thilini K.Wickremasinghe Jing Yang YuanPin Xiao | 2016 | Fungal Diversity2016,,2: | 0 |