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| 1 | Cloning and soluble expression of mature α-luffin from Luffa cylindrica and its antitumor activities in vitro显示文摘Luffin -- 一,一种单个链的类型我使核糖体失去活性的蛋白质,它被知道是最 luffin 家庭并且显然有毒拥有 antitumor 活动,从 Luffa cylindrica 种子被孤立。在现在的学习,成熟 -luffin 从 L 被克隆。cylindrica 和它被发现那成熟 -luffin 分享有 luffin 的 96% 氨基酸类似 -- 一。recombinant 成熟 -luffin 成功地在表示条件的优化以后在 Escherichia coli 在一种部分可溶的形式被表示。细菌的生长上的 recombinant 蛋白质的效果并且它的在里面 vitro 蛋白质合成抑制活动被测试。然后,它对不同人的癌症房间线的 antitumor 活动被 CCK-8 试金和流动 cytometry 评估。结果显示 recombinant -luffin 对 E 稍微有毒。coli。它能在兔子网状细胞 lysate 系统禁止蛋白质合成。同时,它在一个剂量依赖者和时间依赖者举止禁止了肿瘤细胞线的生长。另外, recombinant -luffin 能由 apoptosis 导致房间死亡。向肿瘤房间的 -luffin 的 cytotoxicity 使它成为一个潜在的 antitumor 代理人。 | Liling Liu Rupeng Wang Wei He Fengtian He Gang Huang | 2010 | Acta Biochimica et Biophysica Sinica2010，42，8： | 6 |
| 2 | N2O emissions at municipal solid waste landfill sites:effects of CH4 emissions and cover soil显示文摘 | ZHANG Houhu HE Pinjing SHAO Liling | | 0，，16： | 1 |
| 3 | H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet显示文摘 | Qianyi Zhang Jianzhong Shi Guohua Deng Jing Guo Xianying Zeng Xijun He Huihui Kong Chunyang Gu Xuyong Li Jinxiong Liu Guojun Wang Yan Chen Liling Liu Libin Liang Yuanyuan Li Jun Fan Jinliang Wang Wenhui Li Lizheng Guan Qimeng Li Huanliang Yang Pucheng Che | 2013 | Science2013，，6144： | 1 |
| 4 | Characterizationof the molecular pharmacology of AMD3100:a specificantagonist of the G-protein coupled chemokine receptor,CXCR4显示文摘 | Liles WC Broxmeyer HE Rodger E | 2006 | Biochemical Pharmacology2006，72，5： | 1 |
| 5 | Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100,a CXCR4 antagonist显示文摘 | Liles WC Broxmeyer HE Rodger E | 2003 | Blood2003，102，8： | 1 |
| 6 | Augmented mobi-lization and ollection of CD34+hematopoietic cells fromnormal human volunteers stimulated with granulocyte-colony-stimulatingc factor by single-dose administration ofAMD3100,a CXCR4antagonist显示文摘 | Liles WC Rodger E Broxmeyer HE | 2005 | Transfusion2005，45，3： | 1 |
| 7 | Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100,a CXCR4 antagonist显示文摘 | Broxmeyer HE Rodger E | 2003 | Blood2003，102，8： | 1 |
| 8 | Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist显示文摘 | Liles WC Broxmeyer HE Rodger E | 2003 | Blood2003，102，8： | 1 |
| 9 | Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD 3100, a CXCR 4 antagonist显示文摘 | Liles WC Broxmeyer HE Rodger E | 2003 | Blood2003，102，8： | 1 |
| 10 | A potential mechanism of metformin-mediated regulation of glucose homeostasis: Inhibition of Thioredoxin-interacting protein (Txnip) gene expression显示文摘 | Tin Fan Chai Shin Yee Hong Hongpeng He Liling Zheng Thilo Hagen Yan Luo Fa-Xing Yu | 2012 | Cellular Signalling2012，，8： | 1 |
| 11 | miR?204-5p promotes the adipogenic differentiation of human adipose-derivedmesenchymal stem cells by modulating DVL3 expression and suppressing Wnt/β-cateninsignaling显示文摘 | Honghui He Ke Chen Fang Wang Liling Zhao Xinxing Wan Linghao Wang Zhaohui Mo | 2015 | International Journal of Molecular Medicine2015，，6： | 1 |
| 12 | H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet显示文摘 | Qianyi Zhang Jianzhong Shi Guohua Deng Jing Guo Xianying Zeng Xijun He Huihui Kong Chunyang Gu Xuyong Li Jinxiong Liu Guojun Wang Yan Chen Liling Liu Libin Liang Yuanyuan Li Jun Fan Jinliang Wang Wenhui Li Lizheng Guan Qimeng Li Huanliang Yang Pucheng Che | 2013 | Science2013，，6144： | 1 |
| 13 | Mobilization if Hematopoietic Progenitor Cells in Healthy Volunteers by AMD3100, a CXCR4 Antagonist显示文摘 | Liles W C Broxmeyer HE Rodger E | 2003 | Blood2003，102，8： | 1 |
| 14 | Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist显示文摘 | Liles WC Broxmeyer HE Rodger E | 2003 | Blood2003，102，8： | 1 |
| 15 | Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100,a CXCR4 antagonist显示文摘 | Liles WC Broxmeyer HE Rodger E | | 0，，08： | 1 |
| 16 | Modeling on Mass Abrasion of Kinetic Energy Penetrator显示文摘 | ]Chen Xiaowei He Liling Yang Shiquan | 2010 | European Journal of Mechanics A/Solids2010，29，1： | 1 |
| 17 | Analyses of the Penetration Process Considering Mass Loss显示文摘 | He Liling Chen Xiaowei | 2011 | European Journal of Mechanics A/Solids2011，30，2： | 1 |
| 18 | Mycorrhizal Networks Interacting with Litter Improves Nutrients and Growth for One Plant through the Vary of N/P Ratio under Karst Soil显示文摘Arbuscular mycorrhizae(AM)fungi affect nutrient uptake for host plants,while it is unclear how AM fungi interacting with soil litter affect plant growth and nutrient utilization through mycorrhizal networks in karst soil of deficient nutrients beyond the rhizosphere.An experiment was conducted in a microcosm composed of a planting compartment for Cinnamomum camphora seedlings with or without Glomus mosseae fungus(M+vs.M−)and an adjacent litter compartment containing or not containing additional litter material of Arthraxon hispidus(L+vs.L−),where the compartments are connected either by nylon mesh of 20μm or 0.45μm which either allow available mycorrhizal networks within the litter compartment or prevent mycelium entering into the litter compartment(N+vs.N−).Plant biomass and nutrients were measured.The results showed that the addition of litter changed the symbiotic process in mycorrhizal colonization,spore,and hyphal density,which when in association with the host plant then affected the biomass,and accumulations of N(nitrogen)and P(phosphorus)in the individual plant as well as root,stem,and leaf respectively.AM fungi increased N and P accumulations and N/P ratio in individual plants and plant tissues.A decrease of the N/P ratio of the individual plant was observed when AM fungus interacted significantly with litter through mycorrhizal networks in the litter compartment.The results indicate that the C.camphora seedlings benefited from litter in nutrient utilization of N and P through the vary of N/P ratio when accessing mycorrhizal networks.These findings suggest that mycorrhizal networks interacting with litter improve growth and nutrients of N and P for plants through the vary of N/P ratio in order to alleviate nutrient limitation under karst soil. | Liling Kang Yuejun He Lipeng Zang Jianpeng Si Ying Yang Kaiping Shen Tingting Xia Qiyu Tan Bangli Wu Yun Guo Wei Wang Qin Liang | 2021 | Phyton-International Journal of Experimental Botany2021，90，3： | 0 |
| 19 | Collision-avoidance path planning for multi-ship encounters considering ship manoeuvrability and COLREGs显示文摘Ship collision prevention has always been a hot topic of research for navigation safety.Recently,autonomous ships have gained much attention as a means of solving collision problems by machine control with a collision-avoidance algorithm.An important question is how to determine optimal path planning for autonomous ships.This paper proposes a path-planning method of collision avoidance for multi-ship encounters that is easy to realize for autonomous ships.The ship course-control system uses fuzzy adaptive proportion-integral-derivative(PID)control to achieve real-time control of the system.The automatic course-altering process of the ship is predicted by combining the ship-motion model and PID controller.According to the COLREGs,ships should take different actions in different encounter situations.Therefore,a scene-identification model is established to identify these situations.To avoid all the TSs,the applicable course-altering range of the OS is obtained by using the improved velocity obstacle model.The optimal path of collision avoidance can be determined from an applicable course-altering range combined with a scene-identification model.Then,the path planning of collision avoidance is realized in the multi-ship environment,and the simulation results show a good effect.The method conforms to navigation practice and provides an effective method for the study of collision avoidance. | Yixiong He Zhaoran Li Junmin Mou Weixuan Hu Liling Li Bing Wang | 2021 | Transportation Safety and Environment2021，3，2： | 0 |
| 20 | AF9YEATS结构域在分子层面偶联组蛋白巴豆酰化和活跃转录显示文摘染色质结合蛋白质模块(“阅读器”)识别组蛋白共价修饰构成表观遗传调控的主要方式之一,例如溴域识别乙酰化赖氨酸修饰。除乙酰化之外,近来研究发现组蛋白赖氨酸还能发生巴豆酰化、丁酰化、丙酰化等酰基化修饰.但能够偏好识别这些新型酰基化修饰的阅读器尚未见报道。 | Yuanyuan Li Benjamin R.Sabari Tatyana Panchenko Hong Wen Dan Zhao Haipeng Guan Liling Wan He Huang Zhanyun Tang Yingming Zhao Robert G.Roeder Xiaobing Shi C.David Allis 李海涛 | 2017 | 科学新闻2017，19，4： | 0 |
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