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4篇 您的检索式:作者名="Hecheng Han"
    题名 作者 年代 出处 被引量
1Recent Advancements on Photothermal Conversion and Antibacterial Applications over MXenes-Based Materials显示文摘The pernicious bacterial proliferation and emergence of super-resistant bacteria have already posed a great threat to public health,which drives researchers to develop antibiotic-free strategies to eradicate these fierce microbes.Although enormous achievements have already been achieved,it remains an arduous challenge to realize efficient sterilization to cut off the drug resistance generation.Recently,photothermal therapy(PTT)has emerged as a promising solution to efficiently damage the integrity of pathogenic bacteria based on hyperthermia beyond their tolerance.Until now,numerous photothermal agents have been studied for antimicrobial PTT.Among them,MXenes(a type of two-dimensional transition metal carbides or nitrides)are extensively investigated as one of the most promising candidates due to their high aspect ratio,atomic-thin thickness,excellent photothermal performance,low cytotoxicity,and ultrahigh dispersibility in aqueous systems.Besides,the enormous application scenarios using their antibacterial properties can be tailored via elaborated designs of MXenes-based materials.In this review,the synthetic approaches and textural properties of MXenes have been systematically presented first,and then the photothermal properties and sterilization mechanisms using MXenes-based materials are documented.Subsequently,recent progress in diverse fields making use of the photothermal and antibacterial performances of MXenes-based materials are well summarized to reveal the potential applications of these materials for various purposes,including in vitro and in vivo sterilization,solar water evaporation and purification,and flexible antibacterial fabrics.Last but not least,the current challenges and future perspectives are discussed to provide theoretical guidance for the fabrication of efficient antimicrobial systems using MXenes.Shuyan Hao Hecheng Han Zhengyi Yang Mengting Chen Yanyan Jiang Guixia Lu Lun Dong Hongling Wen Hui Li Jiurong Liu Lili Wu Zhou Wang Fenglong Wang 2022Nano-Micro Letters2022,14,11:4
2Shining light on transition metal sulfides:New choices as highly efficient antibacterial agents显示文摘Globally,millions of people die of microbial infection-related diseases every year.The more terrible situation is that due to the overuse of antibiotics,especially in developing countries,people are struggling to fight with the bacteria variation.The emergence of super-bacteria will be an intractable environmental and health hazard in the future unless novel bactericidal weapons are mounted.Consequently,it is critical to develop viable antibacterial approaches to sustain the prosperous development of human society.Recent researches indicate that transition metal sulfides(TMSs)represent prominent bactericidal application potential owing to the meritorious antibacterial performance,acceptable biocompatibility,high solar energy utilization efficiency,and excellent photo-to-thermal conversion characteristics,and thus,a comprehensive review on the recent advances in this area would be beneficial for the future development.In this review article,we start with the antibacterial mechanisms of TMSs to provide a preliminary understanding.Thereafter,the state-of-the-art research progresses on the strategies for TMSs materials engineering so as to promote their antibacterial properties are systematically surveyed and summarized,followed by a summary of the practical application scenarios of TMSs-based antibacterial platforms.Finally,based on the thorough survey and analysis,we emphasize the challenges and future development trends in this area.Hecheng Han Jingjing Yang Xiaoyan Li Yuan Qi Zhengyi Yang Zejun Han Yanyan Jiang Martina Stenzel Hui Li Yixin Yin Yi Du Jiurong Liu Fenglong Wang 2021Nano Research2021,14,8:2
3PtCu-SnO_(2)nanocomposites for ultrasensitive and rapid ultra-low formaldehyde sensing显示文摘SnO 2 nanospheres with diameters of 30∼50 nm and Pt x Cu 1-x bimetallic nanoparticles with sizes of approxi-mately 10 nm were synthesized via hydrothermal and solvothermal methods,respectively.The Pt x Cu 1-x bimetal-lic nanoparticles were impregnated on the surface of the SnO 2 spheres to form Pt x Cu 1-x-SnO 2 nanocomposites.By varying the atomic ratios between platinum(Pt)and copper(Cu),we found that Pt 0.75 Cu 0.25-SnO 2,with a large specific surface area of 89.21 m 2/g,enabled the selective and accurate detection of low-concentration formalde-hyde compared to other metal-deposited samples and pure SnO 2.The response value of Pt 0.75 Cu 0.25-SnO 2 to 500×10−9 formaldehyde was approximately 20 at an operating temperature of 160◦C with an extremely high-speed response(15 s).The porous structures with large specific surface areas,as well as the improved catalytic effects of Pt 0.75 Cu 0.25,comprehensively contributed to the enhanced sensing performance towards formaldehyde.Zejun Han Yunxiang Tang Guixia Lu Yuan Qi Hao Wu Zhengyi Yang Hecheng Han Xue Zhang Lili Wu Zhou Wang Jiurong Liu Fenglong Wang 2022ChemPhysMater2022,1,3:0
4The diverse role of RNA methylation in esophageal cancer显示文摘Esophageal cancer is one of the major life-threatening diseases in the world.RNA methylation is the most common post-transcriptional modification and a wide-ranging regulatory system controlling gene expression.Numerous studies have revealed that dysregulation of RNA methylation is critical for cancer development and progression.However,the diverse role of RNA methylation and its regulators in esophageal cancer remains to be elucidated and summarized.In this review,we focus on the regulation of major RNA methylation,including m6A,m5C,and m7G,as well as the expression patterns and clinical implications of its regulators in esophageal cancer.We systematically summarize how these RNA modifications affect the'life cycle'of target RNAs,including mRNA,microRNA,long non-coding RNA,and tRNA.The downstream signaling pathways associated with RNA methylation during the development and treatment of esophageal cancer are also discussed in detail.Further studies on how these modifications function together in the microenvironment of esophageal cancer will draw a clearer picture of the clinical application of novel and specific therapeutic strategies.Wangyang Meng Yichao Han Bin Li Hecheng Li 2023Acta Biochimica et Biophysica Sinica2023,55,6:0
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