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| 1 | Soil particle size distribution and its relationship with soil water and salt under mulched drip irrigation in Xinjiang of China显示文摘Soil particle size distribution(PSD),one of the most important soil physical attributes,is of great importance to soil water movement,soil erosion and soil solute migration.In this study,the soil PSD of 563 soil samples from the mulched drip irrigated cotton fields in Xinjiang of China were measured by laser diffraction particle size analyzer.The soil PSD characteristics and its relations with soil water and salt were studied by using the combined methods of textural triangle,fractal and multifractal analysis.The results showed very low clay content(about 1.52%) while really high sand content of the studied soil,and a complex shape of bimodal or unimodal of soil PSD.The results also showed that the two indices,i.e.,standard deviation and the peak value of soil particle relative volumes,were good indicators of soil PSD and thus had good relations with fractal and multifractal characteristics.The correlative analysis further indicated that the mulched drip irrigation had a significant impact on the distribution of the soil salt,while this impact withered for the deeper soil layer.The soil texture feature was found to dominate soil water and salt distribution,especially the surface soil salt content and the deep soil water content. | HU HongChang TIAN FuQiang HU HePing | 2011 | Science China(Technological Sciences)2011，54，6： | 33 |
| 2 | Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals显示文摘线粒体为精力新陈代谢和反应的氧种类(ROS ) 的生产是必要的。在未经触动的房间,呼吸线粒体展览自发的 “ superoxide flashes”,对短暂 mitochondrial 渗透转变(tMPT ) 结果的 quantal 生产 ROS 事件。这里,我们在表示 superoxide 生物传感器 mt-cpYFP 的生活老鼠在 mitochondrial superoxide 闪光和 tMPT 活动的 vivo 成像执行第一,并且表明他们联合到整个身体的葡萄糖新陈代谢。柔韧的 tMPT/superoxide 闪光活动发生在骨胳的肌肉和 anesthetized 的臀部的神经转基因的老鼠。在骨胳的肌肉,成像 tMPT/superoxide 闪光揭示了线粒体的迷宫的三维的网络同时地操作。tMPT/superoxide 闪光活动响应全身的葡萄糖挑战或胰岛素刺激澎湃,以一种显然调制频率的方式并且也在 tMPT 的 gating 模式包含移动。因此,在 tMPT 依赖的 mitochondrial ROS 的 vivo 成像,信号和 metabolism-tMPT-superoxide 的发现闪光联合标记为 mitochondrial 功能并且 ROS 处于健康和疾病发信号的学习的重要工艺、概念的进展。 | Huaqiang Fang Min Chen Yi Ding Wei Shang Jiejia Xu Xing Zhang Wanrui Zhang Kaitao Li Yao Xiao Feng Gao Shujiang Shang Jing-Chao Li Xiao-Li Tian Shi-Qiang Wang Jingsong Zhou Noah Weisleder Jianjie Ma Kunfu Ouyang Ju Chen Xianhua Wang Ming Zheng Wang Wang Xiuqin Zhang Heping Cheng | 2011 | Cell Research2011，21，9： | 11 |
| 3 | Thermodynamic watershed hydrological model: Constitutive relationship显示文摘The representative elementary watershed (REW) approach proposed by Reggiani et al. was the first attempt to develop scale adaptable equations applicable directly at the macro scale. Tian et al. extended the initial definition of REW for simulating the energy related processes, and re-organized the deriving procedure of balance equations so that additional sub-regions and substances could be easily incorpo-rated. The resultant ordinary differential equation set can simulate various hydro-logical processes in a physically reasonable way. However, constitutive and geo-metric relationships have not been developed for Tian et al.'s equation set, which are necessary for the thermodynamic watershed hydrological model to apply in hydrological modeling practice. In this work, the constitutive equations for mass exchange terms and momentum exchange terms were developed as well as geo-metric relationships. The closed ordinary differential equation set with nine equa-tions was finally obtained. | TIAN FuQiang HU HePing LEI ZhiDong | 2008 | Science China(Technological Sciences)2008，51，9： | 6 |
| 4 | A two-dimensional numerical model coupled with multiple hillslope hydrodynamic processes and its application to subsurface flow simulation显示文摘A numerical hillslope hydrodynamic model is of great importance in facilitating the understanding of rainfall-runoff mechanism.However,most of the currently existing models do not consider the effect of coupled hydrodynamic processes as runoff,subsurface flow or groundwater flow.In this study,the Tsinghua Hillslope Runoff Model based on multiple hydrodynamic process,THRM model,is developed,which couples with Saint Venant equation for surface runoff and Richards equation for variably saturated soil water movement(including subsurface flow and groundwater flow).A finite difference scheme with improved boundary conditions is adopted in this research.It is revealed from the simulation that the THRM model has a high computational efficiency and stability in simulating subsurface flow of the experimental hillslope,which is valuable in assessing the hillslope runoff generation mechanism.A model based sensitivity analysis is also carried out.The impact of boundary condition,grid size and initial soil moisture on simulation result and model stability are revealed,which provides insightful references to understand the mechanism of subsurface flow. | LAN Min HU HongChang TIAN FuQiang HU HePing | 2013 | Science China(Technological Sciences)2013，56，10： | 6 |
| 5 | Role of JAK-STAT3 signaling pathway during neuronal differentiation of rat bone marrow mesenchymal stem cells显示文摘BACKGROUND: Recent studies regarding neuronal differentiation of mesenchymal stem cells (MSCs) have primarily focused on induction methods and transplantation in vivo.However,knowledge about the intrinsic regulatory mechanisms underlying neuronal induction of MSCs remains limited and unclear.OBJECTIVE: To elucidate the role of JAK-STAT3 signaling pathway during neuronal differentiationof MSCs using a combination of the JAK-STAT3 signaling inhibitor AG490 and growth factors.DESIGN,TIME AND SETTING: Neural,molecular,biomedical,in vitro experiment was performed at the Laboratory of Pharmacology,School of Pharmacy,Nanjing Medical University between Marchand December 2008 MATERIALS: An inhibitor of the JAK-STAT3 signaling pathway was purchased from Calbiochem,USA.Antibody kit for total and phosphorylated STAT3 was purchased from Cell Signaling,USA.METHODS: MSCs from passage 3 were assigned to non-induced,growth factor,and AG490 groups.MAIN OUTCOME MEASURE: The number of cells expressing neuron-specific enolase,microtubule-associated protein,and glial fibrillary acidic protein were determined by immunocytochemistry.Total and phosphorylated (Tyr705) expression levels of STAT3 protein were measured by Western blot analysis.RESULTS: MSCs were transdifferentiated into neuronaland astrocyte-like phenotypes throughthe induction of epidermal growth factor,basic fibroblast growth factor,and brain-derived neurotrophic factor.In addition,the JAK-STAT3 signaling pathway was significantly activated during neural differentiation.Expression of phosphorylated (Tyr705) STAT3 was inhibited with AG490 (5 μmol/L) prior to neural induction with epidermal growth factor,basic fibroblast growth factor,and brain-derived neurotrophic factor;proportion of astrocyte-like cells was significantly reduced (P < 0.01),and the proportion of neuronal-like phenotypes was significantly increased (P < 0.01).CONCLUSION: JAK-STAT3 signaling pathway was shown to regulate neuronal induction of bone marrow MSCs.The proportion of MSC-induced neuronal-like cells was increased following treatment with the JAK-STAT3 signaling inhibitor AG490. | Huaiyong Hao Yongguang Wang Feng Cheng Baosheng Huang Heping Tian Xueliang Dai Lixin Li | 2010 | Neural Regeneration Research2010，5，5： | 2 |
| 6 | Analysis of the effect of regional lateral inflow on the flood peak of the Three Gorges Reservoir显示文摘The Three Gorges Region(TGR),located at the lower reach of the Upper Yangtze River Basin(UYRB) in China,suffers from heavy rainstorm frequently.The runoff generated from TGR composes an important part of the total flood at the famous Three Gorges Reservoir(TGRe).During the severe flood period in 1954,for example,the water from TGR accounted for up to 13.2% of the 30-days maximum flood volume of the UYRB.Considering the short and steep tributaries with rapid concentration,the regional lateral inflow(RLI) may induce more serious effect on the flood peak of the TGRe than the volume.However,hydrological data of the sparse gauge stations is too insufficient to evaluate the effect of RLI.This paper studied the impact by analyzing 880 flood events during 1956-2000.By comparing the observed hydrograph and simulated hydrograph with HEC-RAS software regarding no RLI,the effect of RLI on flood peak value and timing properties was identified and quantified.The variability of this effect among floods of different magnitudes was also analyzed.To evaluate the analysis uncertainty associated with the parameter of roughness coefficient,four sets of roughness coefficients from different research groups were employed in this study.The results showed that RLI contributes discharge of 3524 m3/s to flood peaks of the TGRe on average,with the contribution ratio of 15.9%.RLI contributes 12000 m3/s to the flood peaks larger than 50000 m3/s on average,with 25000 m3/s as its upper bound,while the contribution ratio can reach up to 50%,with an average of 20%.The variability of this effect is great among different events.Statistical analysis showed that to larger flood peak of the TGRe,RLI contributes more discharge with higher variability,and the contribution ratio and its variability are slightly larger,and events with higher contribution ratio occur more frequently.RLI can reshape the hydrograph,leading to earlier appearance of flood peak.This effect and its variability increase with the contribution ratio.This study has revealed that RLI plays an important role in large flood peak of the TGRe,which calls for more reliable flood forecasting methods to prolong the forecast lead time and improve the accuracy for the safety of the Three Gorges Dam and the protection of its lower reaches during severe flood disaster period. | WANG BaiWei TIAN FuQiang HU HePing | 2011 | Science China(Technological Sciences)2011，54，4： | 2 |
| 7 | A two-dimensional Richards equation solver based on CVODE for variably saturated soil water movement显示文摘A numerical model of two-dimensional soil water movement under surface drip irrigation condition was developed. The physical process of soil water movement is described by 2D Richards equation,and the upper boundary condition is depicted by the improved moving ponded area boundary. The partial differential equation(PDE) is transformed into ordinary differential equations(ODEs) through spatial semi-discretization and numerically solved by an ordinary differential equation solver(CVODE) . The numerical and field experiments indicate the good performance of the model in terms of accuracy and efficiency. The model provides a useful tool for long-term simulation of soil water movement under surface drip irrigation. Also,the model can serve as a general 2D Richards equation solver for variably saturated soil water movement,which is named as TIVS model(Tsinghua Integrated Variably Saturated soil water movement model). | TIAN FuQiang GAO Long HU HePing | 2011 | Science China(Technological Sciences)2011，54，12： | 2 |
| 8 | Spatial averaging infiltration model for layered soil显示文摘To quantify the influences of soil heterogeneity on infiltration, a spatial averaging infiltration model for layered soil (SAI model) is developed by coupling the spatial averaging approach proposed by Chen et al. and the Generalized Green-Ampt model proposed by Jia et al. In the SAI model, the spatial hetero- geneity along the horizontal direction is described by a probability distribution function, while that along the vertical direction is represented by the layered soils. The SAI model is tested on a typical soil using Monte Carlo simulations as the base model. The results show that the SAI model can directly incorporate the influence of spatial heterogeneity on infiltration on the macro scale. It is also found that the homogeneous assumption of soil hydraulic conductivity along the horizontal direction will overes- timate the infiltration rate, while that along the vertical direction will underestimate the infiltration rate significantly during rainstorm periods. The SAI model is adopted in the spatial averaging hydrological model developed by the authors, and the results prove that it can be applied in the macro-scale hy- drological and land surface process modeling in a promising way. | HePing Hu ZhiYong Yang FuQiang Tian | 2009 | Science China(Technological Sciences)2009，52，4： | 1 |
| 9 | Ecohydro-logical evolution model on riparian vegetation in hyper-ar-id regions and its validation in the lower reach of TarimRiver显示文摘 | Liu Dengfeng Tian Fuqiang Hu Heping | 2012 | Hydrological Processes2012，26，13： | 1 |
| 10 | Ecohydrological evolution model on riparian vegetation in hyper-arid regions and its validation in the lower reach of Tarim River 显示文摘 | LIU Dengfeng TIAN Fuqiang HU Heping LIN Mu CONG Zhentao | 2012 | Hydrological Processes2012，26，13： | 1 |
| 11 | Extension of the representative elementary watershed approach for cold regions via explicit treatment of energy related processes 显示文摘 | TIAN Fuqiang HU Heping LEI Zhidong | 2006 | Hydrology and Earth System Sciences2006，10，5： | 1 |
| 12 | Features of A New 500 kVAR Static VAR Generator显示文摘The paper briefly describes the main features of a new 500 kVAR static VAR generator designed and manufactured by NAm for industrial test and trial | Chen Xianming Xu Heping Tian Jie Wang Xiaohong Wang Tong (Nanjing Automation Research Institute) | 1998 | Electricity1998，，4： | 1 |
| 13 | Hydnologically enhanced distributed urban drainage model and its application in Beijing City显示文摘 | Aujun Pan Aizhong Hou Fuqiang Tian Guanghen Ni Heping Hu | 2012 | Journal of Hydrological Engineering2012，17，6： | 1 |
| 14 | Robust crop and weed segmentation under uncontrolled outdoor illumination显示文摘 | Hong Y Jeon Lei F Tian Heping Zhu | | 0，，06： | 1 |
| 15 | Lactobacillus plantarum CCFM8661 Alleviates Lead Toxicity in Mice显示文摘 | Fengwei Tian Qixiao Zhai Jianxin Zhao Xiaoming Liu Gang Wang Hao Zhang Heping Zhang Wei Chen | 2012 | Biological Trace Element Research2012，，1： | 1 |
| 16 | Characteristics of soil water retention curve at macro-scale显示文摘Scale adaptable hydrological models have attracted more and more attentions in the hydrological modeling research community, and the constitutive relationship at the macro-scale is one of the most important issues, upon which there are not enough research activities yet. Taking the constitutive relationships of soil water movement--soil water retention curve (SWRC) as an example, this study extends the definition of SWRC at the micro-scale to that at the macro-scale, and aided by Monte Carlo method we demonstrate that soil property and the spatial distribution of soil moisture will affect the features of SWRC greatly. Furthermore, we assume that the spatial distribution of soil moisture is the result of self-organization of climate, soil, ground water and soil water movement under the specific boundary conditions, and we also carry out numerical experiments of soil water movement at the vertical direction in order to explore the relationship between SWRC at the macro-scale and the combinations of climate, soil, and groundwater. The results show that SWRCs at the macro-scale and micro-scale presents totally different features, e.g., the essential hysteresis phenomenon which is exaggerated with increasing aridity index and rising groundwater table. Soil property plays an important role in the shape of SWRC which will even lead to a rectangular shape under drier conditions, and power function form of SWRC widely adopted in hydrological model might be revised for most situations at the macro-scale. | TIAN FuQiang MOU LiQin HU HePing | 2009 | Science China(Technological Sciences)2009，52，10： | 1 |
| 17 | High-performance thin-layer chromatographic fingerprints of isoflavonoids for distinguishing between Radix Puerariae Lobate and Radix Puerariae Thomsonii显示文摘 | CHEN Sibao LIU Heping TIAN Runtao | | 0，，01： | 1 |
| 18 | Eco- hydrological evolution model on riparian vegetation in hy- perarid regions and its validation in the lower reach of Tar- im River显示文摘 | Liu Dengfeng Tian Fuqiang Hu Heping | 2012 | Hydrological Processes2012，26，13： | 1 |
| 19 | Expert consensus on prevention and cardiopulmonary resuscitation for cardiac arrest in COVID-19显示文摘Background:Cardiopulmonary resuscitation(CPR)strategies in COVID-19 patients differ from those in patients suffering from cardiogenic cardiac arrest.During CPR,both healthcare and non-healthcare workers who provide resuscitation are at risk of infection.The Working Group for Expert Consensus on Prevention and Cardiopulmonary Resuscitation for Cardiac Arrest in COVID-19 has developed this Chinese Expert Consensus to guide clinical practice of CPR in COVID-19 patients.Main recommendations:1)A medical team should be assigned to evaluate severe and critical COVID-19 for early monitoring of cardiac-arrest warning signs.2)Psychological counseling and treatment are highly recommended,since sympathetic and vagal abnormalities induced by psychological stress from the COVID-19 pandemic can induce cardiac arrest.3)Healthcare workers should wear personal protective equipment(PPE).4)Mouth-to-mouth ventilation should be avoided on patients suspected of having or diagnosed with COVID-19.5)Hands-only chest compression and mechanical chest compression are recommended.6)Tracheal-intubation procedures should be optimized and tracheal-intubation strategies should be implemented early.7)CPR should be provided for 20-30 min.8)Various factors should be taken into consideration such as the interests of patients and family members,ethics,transmission risks,and laws and regulations governing infectious disease control.Changes in management:The following changes or modifications to CPR strategy in COVID-19 patients are proposed:1)Healthcare workers should wear PPE.2)Hands-only chest compression and mechanical chest compression can be implemented to reduce or avoid the spread of viruses by aerosols.3)Both the benefits to patients and the risk of infection should be considered.4)Hhealthcare workers should be fully aware of and trained in CPR strategies and procedures specifically for patients with COVID-19. | Wei Song Jie Wei Xiangdong Jian Deren Wang Yanhong Ouyang Yuanshui Liu Xianjin Du Ying Chen Yingqi Zhang Heping Xu Shuming Xianyu Qiong Ning Xiang Li Xiaotong Han Feng Zhan Tao Yu Wenteng Chen Jun Zhang Wenwei Cai Sheng’ang Zhou Shengyang Yi Yu Cao Xiaobei Chen Shunjiang Xu Zong’an Liang Duohu Wu Fen Ai Zhong Wang Qingyi Meng Yuhong Mi Sisen Zhang Rongjia Yang Shouchun Yan Wenbin Han Yong Lin Chuanyun Qian Wenwu Zhang Yan Xiong Jun Lv Baochi Liu Yan Cao Xiaojun He Xuelian Sun Yufang Cao Tian’en Zhou | 2021 | Asian Pacific Journal of Tropical Medicine2021，14，6： | 0 |
| 20 | Executive summary of Chinese expert consensus for topical application of anti-microbial agents for lower respiratory tract infection in adults显示文摘In recent years,with the increased prevalence of multi-drug resistant(MDR)bacterial infection and chronic pulmonary infection,the topical application of anti-microbial agents,mainly inhaled antibiotics,has come back to clinical practice.Several formulations for nebulization and dry powder inhaler(DPI)have been approved for inhaled anti-infective therapy.Meanwhile,evidence and experience have been accumulated in the use of anti-microbial agents delivered via airway.However,the available studies in this field are heterogenous in the study population,drug delivery route and dosages.The efficacy and safety of inhaled anti-infective therapy in various types of lower respiratory tract infections(LRTIs)need to be evaluated.Moreover. | Jing Zhang Qijian Cheng Yi Huang Hong Fan Guoxiang Lai Xiangdong Mu Wei Sha Danyang She Ning Shen Xin Su Jinfu Xu Feng Ye Xinlun Tian Tiantuo Zhang Hua Zhou Youning Liu Lixian He Heping Xiao Bei He Yi Shi Xiangyan Zhang Bin Cao Jieming Qu on behalf of Pulmonary Infection Assembly of Chinese Thoracic Society | 2022 | Chinese Medical Journal2022，135，22： | 0 |
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