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| 1 | Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals显示文摘线粒体为精力新陈代谢和反应的氧种类(ROS ) 的生产是必要的。在未经触动的房间,呼吸线粒体展览自发的 “ superoxide flashes”,对短暂 mitochondrial 渗透转变(tMPT ) 结果的 quantal 生产 ROS 事件。这里,我们在表示 superoxide 生物传感器 mt-cpYFP 的生活老鼠在 mitochondrial superoxide 闪光和 tMPT 活动的 vivo 成像执行第一,并且表明他们联合到整个身体的葡萄糖新陈代谢。柔韧的 tMPT/superoxide 闪光活动发生在骨胳的肌肉和 anesthetized 的臀部的神经转基因的老鼠。在骨胳的肌肉,成像 tMPT/superoxide 闪光揭示了线粒体的迷宫的三维的网络同时地操作。tMPT/superoxide 闪光活动响应全身的葡萄糖挑战或胰岛素刺激澎湃,以一种显然调制频率的方式并且也在 tMPT 的 gating 模式包含移动。因此,在 tMPT 依赖的 mitochondrial ROS 的 vivo 成像,信号和 metabolism-tMPT-superoxide 的发现闪光联合标记为 mitochondrial 功能并且 ROS 处于健康和疾病发信号的学习的重要工艺、概念的进展。 | Huaqiang Fang Min Chen Yi Ding Wei Shang Jiejia Xu Xing Zhang Wanrui Zhang Kaitao Li Yao Xiao Feng Gao Shujiang Shang Jing-Chao Li Xiao-Li Tian Shi-Qiang Wang Jingsong Zhou Noah Weisleder Jianjie Ma Kunfu Ouyang Ju Chen Xianhua Wang Ming Zheng Wang Wang Xiuqin Zhang Heping Cheng | 2011 | Cell Research2011，21，9： | 11 |
| 2 | A series of naphthalimide azoles: Design, synthesis and bioactive evaluation as potential antimicrobial agents显示文摘A series of naphthalimide azoles as potential antibacterial and antifungal agents were conveniently and efficiently synthesized starting from commercially available 6-bromobenzo[de]isochromene-1,3-dione. All the new compounds were characterized by NMR, IR, MS and HRMS spectra. Their antimicrobial activities were evaluated against four Gram-positive bacteria, four Gram-negative bacteria and two fungi using two-fold serial dilution technique. The biological assay indicated that most of the prepared compounds exhibited inhibition to the tested strains. In particular, the triazolium derivatives not only gave higher efficacy than their corresponding precursory azoles, but also demonstrated comparable or even better potency than the reference drugs Chloromycin, Orbifloxacin and Fluconazole. Some factors including structural fragments, pH and ClogP values of the target molecules were also preliminarily discussed. | DAMU Guri L. V. WANG QingPeng ZHANG HuiZhen ZHANG YiYi LV JingSong ZHOU ChengHe | 2013 | Science China Chemistry2013，56，7： | 8 |
| 3 | H-O-S-Cu-Pb Isotopic Constraints on the Origin of the Nage Cu-Pb Deposit, Southeast Guizhou Province, SW China显示文摘The Nage Cu-Pb deposit,a new found ore deposit in the southeast Guizhou province,southwest China,is located on the southwestern margin of the Jiangnan Orogenic Belt.Ore bodies are hosted in slate and phyllite of Neoproterozoic Jialu and Wuye Formations,and are structurally controlled by EW-trending fault.It contains Cu and Pb metals about 0.12 million tonnes with grades of 0.2 wt% to 3.4 wt% Cu and 1.1 wt% to 9.27 wt% Pb.Massive and disseminated Cu-Pb ores from the Nage deposit occur as either veinlets or disseminations in silicified rocks.The ore minerals include chalcopyrite,galena and pyrite,and gangue minerals are quartz,sericite and chlorite.The H-O isotopic compositions of quartz,S-Cu-Pb isotopic compositions of sulfide minerals,Pb isotopic compositions of whole rocks and ores have been analyzed to trace the sources of ore-forming fluids and metals for the Nage Cu-Pb deposit.The δ65CuNBS values of chalcopyrite range from-0.09% to +0.33‰,similar to basic igneous rocks and chalcopyrite from magmatic deposits.δ65CuNBS values of chalcopyrite from the early,middle and final mineralization stages show an increasing trend due to63Cu prior migrated in gas phase when fluids exsolution from magma.δ34SCDT values of sulfide minerals range from 2.7‰ to +2.8‰,similar to mantle-derived sulfur(0±3‰).The positive correlation between δ65CuNBS and δ34SCDT values of chalcopyrite indicates that a common source of copper metal and sulfur from magma.δDH2OSMOW and δ18OH2O-SMOW values of water in fluid inclusions of quartz range from 60.7‰ to 44.4‰ and +7.9‰ to +9.0‰(T=260°C),respectively and fall in the field for magmatic and metamorphic waters,implicating that mixed sources for H2O in hydrothermal fluids.Ores and sulfide minerals have a small range of Pb isotopic compositions(208Pb/204Pb=38.152 to 38.384,207Pb/204Pb=15.656 to 17.708 and 206Pb/204Pb=17.991 to 18.049) that are close to orogenic belt and upper crust Pb evolution curve,and similar to Neoproterozoic host rocks(208Pb/204Pb=38.201 to 38.6373,207Pb/204Pb=15.648 to 15.673 and 206Pb/204Pb=17.820 to 18.258),but higher than diabase(208Pb/204Pb=37.830 to 38.012,207Pb/204Pb=15.620 to 15.635 and206Pb/204Pb=17.808 to 17.902).These results imply that the Pb metal originated mainly from host rocks.The H-O-S-Cu-Pb isotopes tegather with geology,indicating that the ore genesis of the Nage Cu-Pb deposit is post-magmatic hydrothermal type. | ZHOU Jiaxi WANG Jingsong YANG Dezhi LIU Jinhai | 2013 | Acta Geologica Sinica(English Edition)2013，87，5： | 7 |
| 4 | Oceanic pycnocline depth retrieval from SAR imagery in the existence of solitary internal waves显示文摘Oceanic pycnocline depth is usually inferred from in situ measurements. It is attempted to estimate the depth remotely. As solitary internal waves occur on oceanic pycnocline and propagate along it, it is possible to retrieve the depth indirectly in virtue of the solitary internal waves. A numerical model is presented for retrieving the pycnocline depth from synthetic aperture radar (SAR) images where the solitary internal waves are visible and when ocean waters are fully stratified. This numerical model is constructed by combining the solitary internal wave model and a two-layer ocean model. It is also assumed that the observed groups of solitary internal wave packets on the SAR imagery are generated by local semidiurnal tides. A case study in the East China Sea shows a good agreement with in situ CTD (conductivity-temperature-depth) data. | YANG Jingsong HUANG Weigen XIAO Qingmei ZHOU Chenghu HSU Mingkuang | 2005 | Acta Oceanologica Sinica2005，24，5： | 5 |
| 5 | Mitochondrial Ca^(2+) uptake in skeletal muscle health and disease显示文摘Muscle uses Ca^(2+) as a messenger to control contraction and relies on ATP to maintain the intracellular Ca^(2+) homeostasis. Mitochondria are the major sub-cellular organelle of ATP production. With a negative inner membrane potential, mitochondria take up Ca^(2+) from their surroundings, a process called mitochondrial Ca^(2+) uptake. Under physiological conditions, Ca^(2+) uptake into mitochondria promotes ATP production. Excessive uptake causes mitochondrial Ca^(2+) overload, which activates downstream adverse responses leading to cell dysfunction. Moreover, mitochondrial Ca^(2+) uptake could shape spatio-temporal patterns of intracellular Ca^(2+) signaling. Malfunction of mitochondrial Ca^(2+) uptake is implicated in muscle degeneration. Unlike non-excitable cells, mitochondria in muscle cells experience dramatic changes of intracellular Ca^(2+) levels. Besides the sudden elevation of Ca^(2+) level induced by action potentials, Ca^(2+) transients in muscle cells can be as short as a few milliseconds during a single twitch or as long as minutes during tetanic contraction, which raises the question whether mitochondrial Ca^(2+) uptake is fast and big enough to shape intracellular Ca^(2+) signaling during excitation-contraction coupling and creates technical challenges for quantification of the dynamic changes of Ca^(2+) inside mitochondria. This review focuses on characterization of mitochondrial Ca^(2+) uptake in skeletal muscle and its role in muscle physiology and diseases. | Jingsong Zhou Kamal Dhakal Jianxun Yi | 2016 | Science China(Life Sciences)2016，59，8： | 3 |
| 6 | Removal of uranium (VI) from aqueous solution by adsorption of hematite显示文摘 | Xie Shuibo Zhang Chun Zhou Xinghuo Yang Jing Zhang Xiaojian Wang Jingsong | 2008 | Journal of Environmental Radioactivity2008，，2： | 1 |
| 7 | Factors impacting gaseous mercury speciation in postcombustion 显示文摘 | ZHOU Jingsong LUO Zhongyang HU Changxing | 2007 | Energy Fuels2007，21，2： | 1 |
| 8 | Climate suitability of the distribution of the winter wheat cultivation zone in China显示文摘 | SUN Jingsong ZHOU Guangsheng SUI XingHua | 2012 | European Journal of Agronomy2012，43，： | 1 |
| 9 | Nanomechanics of individual amyloid fibrils using atomic force microscopy显示文摘Compression elasticity of glucagon amyloid fibrils in the transverse direction was investigated by a nanoindentation approach based on atomic force microscopy (AFM).With force-volume mapping, we obtained the correlations between radially applied force and compression of amyloid fibrils, from which the radial compressive elasticity can be deduced.The estimated elastic modulus at three typical locations of fibrils varied from (0.72±0.80) GPa to (1.26±0.62) GPa under small external forces, imply-ing the structural heterogeneity of different fibrils. | ZHOU XingFei CUI ChengYi ZHANG JinHai LIU JianHua LIU JingSong | 2010 | Chinese Science Bulletin2010，55，16： | 1 |
| 10 | Improvement of exo-polysaccharides production and modeling kinetics by Armillaria luteo-virens Sacc,in submerged cultivation显示文摘 | JIAO Yingchun CHEN Qihe ZHOU Jingsong | 2008 | LWT-Food Science and Technology2008，41，9： | 1 |
| 11 | Separation and structural elucidation of a polysaccharide CC30w-1 from the fruiting body of Coprinus comatus显示文摘 | Zhou Shuai Liu Yanfang Yang Yan Jia Wei Tang Qingjiu Tang Chuanhong Feng Na Zhang Jingsong | 2013 | Bioactive Carbohydrates and Dietary Fibre2013，1，2： | 1 |
| 12 | Structural characteristics and hypoglycemic activity of polysaccharides from Coprinus comatus显示文摘 | Liu Yanfang Zhao Yuan Yang Yan Tang Qingjiu Zhou Shuai Wu di Zhang Jingsong | 2013 | Bioactive Carbohydrates and Dietary Fibre2013，2，2： | 1 |
| 13 | Control of an Intermittent Outbreak Caused by an Emerging Pandrug-Resistant Acinetobacter baumannii Clone ST457 in a Tertiary Hospital显示文摘Acinetobacter baumannii is a frequent cause of nosocomial infections.Here we report an intermittent outbreak caused by the emerging carbapenem-resistant A.baumannii(CRAB)clone ST457 and assess the effectiveness of patient screening for outbreak control.CRAB isolates were collected from 74 patients admitted to the respiratory intensive care unit of a tertiary hospital between May 2018 and March 2019.Fourteen CRAB isolates were assigned to ST457,and 13 belonged to an outbreak clone,as determined by phylogenomic analysis.Strict patient screening was started at the respiratory intensive care unit on May 2019,through which a ST457-positive patient transferred from the intensive care unit was detected.No positive patients were detected within 3months onwards.The results of this study highlight the importance of rigorous infection prevention and control measures,combined with patient screening,in controlling the CRAB outbreak. | Chuqiu Zhang Tingting Xu Yang Ji Wenping Zheng Jingsong Wu Yuemei Lu Huiping Li Rongchang Chen Chen Qiu Kai Zhou | 2021 | Infectious Microbes & Diseases2021，3，4： | 1 |
| 14 | Nitrogen Contamination in the Yellow River Basin of China显示文摘 | Xinghui Xia Jingsong Zhou Zhifeng Yang | 2002 | Environ Qual2002，，31： | 1 |
| 15 | Molecular mapping of two semidwarf genes in an indica rice variety Aitaiyin3(Oryza sativa L.)显示文摘Genetic analysis established that Aitaiyin3,a dwarf rice variety derived from a semidwarf cultivar Taiyin1,carries two recessive semidwarf genes.By using simple sequence repeat(SSR)markers,we mapped the two semidwarf genes,sd-1 and sd-t2 on chromosomes 1 and 4,respectively.Sd-t2 was thus named because the semidrawf gene sd-t has already been identified from Aitaiyin 2 whose origin could be traced back to Taiyin1.The result of the molecular mapping of sd-1 gene revealed it is linked to four SSR markers found on chromosome 1.These markers are:RM297,RM302,RM212,and OSR3 spaced at 4.7 cM,0 cM,0.8cM and 0 cM,respectively.Sd-t2 was found to be located on chromosome 4 using five SSR markers:two markers,SSR332 and RM1305 located proximal to sd-t2 are spaced 11.6 cM,3.8 cM,respectively,while the three distally located primers,RM5633,RM307,and RM401 are separated by distances of 0.4 cM,0.0 cM,and 0.4 cM,respectively. | Zhao Xiangqiang Liang Guohua Zhou Jingsong Yan Changjie Cao Xiaoying Gu Minghong | 2006 | Frontiers in Biology2006，1，2： | 0 |
| 16 | Manipulation of plant height in garden asparagus (Asparagus officinalis L.) through CRISPR/Cas9-mediated aspSPL14 allele editing显示文摘Dear Editor,Reduction in plant height has been associated with yield increases and yield stability in a number of important crop species,such as wheat and rice[1].In these plants,dwarfing is mainly attributed to the inability to synthesize or respond to certain phytohormones,predominantly gibberellin(GA)[2].Ideal Plant Architecture 1(IPA1),an miR156 target gene,encodes SPL14 and it is able to bind directly to the promoters of multiple GA biosynthetic,signal,and deactivating genes in rice[3].Moreover,IPA1 loss-of-function mutants exhibit dwarf phenotypes[4]. | Jingsong Zhou Reqing He Xiaojing Liu Bingbing Zhang Guangyu Chen Dong Wang Youlin Zhu | 2023 | Horticulture Research2023，10，7： | 0 |
| 17 | Hopf Structure for a Two-Parameter Deformed Boson Oscillator Algebra显示文摘The Hopf algebraic structure,i.e.,comultiplication,coinverse and counit,is presented for a two-parameter deformed boson oscillator algebra.This result shows that the two-parameter deformed boson oscillator algebra is a Hopf algebra which is neither commutative nor cocommutative. | ZHOU Huanqiang GUAN Xiwen HE Jingsong | 1995 | Chinese Physics Letters1995，12，3： | 0 |
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