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23篇 您的检索式：作者名="Hidalgo MA"

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	题名	作者	年代	出处	被引量
1	Exploiting novel molecular targets in gastrointestinal cancers显示文摘Novel molecular targets are being discovered as we learn more about the aberrant processes underlying various cancers. Efforts to translate this knowledge are starting to impact on the care of patients with gastrointestinal cancers. The epidermal growth factor receptor (EGFR) pathway and angiogenesis have been targeted successfully in colorectal cancer with cetuximab, panitunumab and bevacizumab. Similarly, EGFR-targeting with erlotinib yielded significant survival benefit in pancreatic cancer when combined with gemcitabine. The multi-targeting approach with sorafenib has made it the first agent to achieve significant survival benefit in hepatocellular carcinoma. Efforts to exploit the dysregulated Akt/mTOR pathway in GI cancer therapy are ongoing. These molecular targets can be disrupted by various approaches, including the use of monoclonal antibody to intercept extracellular ligands and disrupt receptor-ligand binding, and small molecule inhibitors that interrupt the activation of intracellular kinases.	Wen W Ma Manuel Hidalgo	2007	World Journal of Gastroenterology2007，13，44：	3
2	Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)显示文摘	Bentley SD Chater KF Cerdeno-Tarraga AM Challis GL Thomson NR James KD Harris DE Quail MA Kieser H Harper D Bateman A Brown S Chandra G Chen CW Collins M Cronin A Fraser A Goble A Hidalgo J Hornsby T Howarth S Huang CH Kieser T Larke L Murphy L Oliver K O		0，，：	1
3	Incisional hernia in patients at risk : can it be prevented? 显示文摘	Hidalgo MP Ferrero EH Ortiz MA	2011	Hernia2011，15，4：	1
4	Phase Ⅰ and pharmacologic study of PN401 and fluorouracil in patients with advanced solid malignancies显示文摘	Hidalgo M Villalona MA Eckhardt SG	2000	J Clin Oncol2000，18，1：	1
5	fM LP-Induced IL-8Release Is Dependenton NADPH Oxidase in Human Neutrophils显示文摘	Hidalgo MA Carretta MD Teuber SE	2015	Journal of Immunology Research2015，，30：	1
6	Effectiveness of combining statistical tests and effect sizes when using logistic discriminant function regression to detect differential item functioning for polytomous items 显示文摘	Juana G6mez-Benito Ma Dolores Hidalgo Bruno D Zum- bo	2013	Educational and Psychological Measurement2013，73，5：	1
7	Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)显示文摘	Bentley SD Chater KF Cerdeno-Tarraga AM Challis GL Thomson NR James KD Harris DE Quail MA Kieser H Harper D Bateman A Brown S Chandra G Chen CW Collins M Cronin A Fraser A Goble A Hidalgo J Hornsby T Howarth S Huang CH Kieser T Larke L Murphy L Oliver K O		0，，：	1
8	Primary bullous disease of the lung in a young male marijuana smoker显示文摘	Núnez Delgado Y Eisman Hidalgo M Valero González MA		0，，11：	1
9	Andrographolide interferes with binding of nuclear factor kappa B to DNA in HL - 60 derived neutrophilic cell显示文摘	Hidalgo MA Romero A Figueroa J	2005	Br J Pharmacol2005，144，5：	1
10	Platelet-activating factor increases pH (i) in bovineneutrephils through the PI3K-ERKI/2 pathway显示文摘	Hidalgo MA Ojeda F Eyre P	2004	Br J Pharmacol2004，141，2：	1
11	Andrographolide interferes with binding of nuclear factor-kappaB to DNA in HL-60-derived neutro- philic cells显示文摘	Hidalgo MA Romero A Figueroa J Cortes P Concha II Hancke JL	2005	Br J Pharmacol2005，144，5：	1
12	Propionate induces the release of granules from bovine neutrophils 显示文摘	Carretta M Conejeros I Hidalgo MA	2013	J Dairy Sci2013，96，4：	1
13	IneealeitoI, an analog of 1, 25 (OH)2D3, displays enhanced antitumor activity through the induction of apoptosis in a squamous cell carcinoma model system 显示文摘	Ma Y Yu WD Hidalgo AA	2013	CellCycle2013，12，5：	1
14	The Winning Formulation: The Development of Paclitaxel in Pancreatic Cancer显示文摘	Wen Wee Ma Manuel Hidalgo	2013	Clinical Cancer Research2013，，20：	1
15	Andrographolide intederswith binding of nuclear factor-kappa B to DNA in HL-60-derived neutrophilic cells 显示文摘	Hidalgo MA Romero A Figueroa J	2005	Br J Pharmacol2005，144，5：	1
16	Andrographolide interferes with binding of nuclear factor - κB to DNA in HL - 60 - derived neu- trophilic cells 显示文摘	Hidalgo MA Romero A Figueroa J	2005	Br J Pharmacol2005，144，5：	1
17	Physiological changes of sturgeon Acipenser naccarii caused by increasing environmental salinity显示文摘	Ma?tinez-álvarez R M Hidalgo M C Domezain A	2002	J Exp Biol2002，205，：	1
18	Primary bullous disease of the lung in a young male marijuana smoker显示文摘	Núez Delgado Y Eisman Hidalgo M Valero González MA	2012	Arch Bronconeumol2012，48，：	1
19	Exposure of health workers in primary health care to glutaraldehyde 显示文摘	Gonzalez Jara MA Mora Hidalgo A Avalos Gulin JC	2013	J Occup MedToxicol2013，8，1：	1
20	Metallothionein and stresscombine to affect multiple organ systems显示文摘	Lynes MA Hidalgo J Manso Y	2014	Cell Stress Chaperones2014，19，5：	1

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