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4篇 您的检索式：作者名="Hiromichi Okamura"

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		题名	作者	年代	出处	被引量
	1	Low-intensity walking as mild medication for pressure control in prehypertensive and hypertensive subjects:how far shall we wander?显示文摘Successful prevention and treatment of hypertension depend on the appropriate combination of antihypertensive drug therapy and nondrug lifestyle modi?cation. While most hypertension guidelines recommend moderate- to high-intensity exercise, we decided to explore a mild yet effective type of exercise to add to hypertension management, especially in populations with complications or frailty. After comparing the short-term cardiovascular effects of low-speed walking versus high-speed walking for 3 kilometers (km)(3 km/h versus 6 km/h) in young, healthy volunteers, we delivered low-speed walking (low-intensity walking, 2.5 metabolic equivalents of task, METs) as exercise therapy in 42 prehypertensive and 43 hypertensive subjects. We found that one session of 3 km low-intensity walking exerted a transient pressure-lowering effect as well as a mild negative chronotropic effect on heart rate in both the prehypertensive and hypertensive subjects;these short-term bene?ts on blood pressure and heart rate were accompanied by a brief increase in urine β-endorphin output. Then we prescribed regular low-intensity walking with a target exercise dose (exercise volume) of 500–1000 METs·min/week (50–60 min/day and 5–7 times/week) in hypertensive subjects in addition to their daily activities. Regular low-intensity walking also showed mild but signi?cant blood pressure-lowering and heart rate-reducing effects in 7 hypertensive subjects within two months. It is hypothesized that regular low-intensity exercise of the necessary dose could be taken as a pragmatic and supplementary medication for hypertension management.	Qin Lu Sheng-ming Wang Yi-xiao Liu Hong Chen Rui Zhang Wen-hui Zhang Yuan-yuan Zou Jia-wei Zhou Xin-yi Guo Ying Zhang Teng-Li Huang Yu-hang Liu Si-qi Zhang Kyosuke Yamanishi Hiromichi Yamanishi Hideaki Higashino Haruki Okamura	2019	Acta Pharmacologica Sinica2019，40，8：	2
	2	Follow-up study of combination treatment (TAE and PEIT) for unresectable hepatocellular carcinoma显示文摘	Hideo Tateishi Masakatsu Kinuta Junkou Furukawa Naoki Takata Hirohide Maruyama Hiromichi Oi Eiji Yayoi Jun Okamura	1994	Cancer Chemotherapy and Pharmacology1994，，1：	1
	3	Preparation and sintering of narrow-sized Al2O3- TiO2 composite powders显示文摘	Hiromichi Okamura Eric A Barringer H Kent Bowen	1994	J Mater SCI1994，24，18：	1
	4	Long-Term Outcome of Treatment With Protocols AL841, AL851, and ALHR88 in Children With Acute Lymphoblastic Leukemia: Results Obtained by the Kyushu-Yamaguchi Children’s Cancer Study Group显示文摘	Akinobu Matsuzaki Eiichi Ishii Yoshihisa Nagatoshi Haruhiko Eguchi Hiroyuki Koga Fumio Yanai Hiroko Inada Keiko Nibu Yuji Tamai Kensuke Akiyoshi Hideki Nakayama Toshiro Hara Hiromichi Take Sumio Miyazaki Jun Okamura	2001	International Journal of Hematology2001，，3：	1

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