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| 1 | SPSBl-mediated HnRNP A1 alternative splicing and cell ubiquitylation regulates migration in EGF signaling显示文摘细胞外的信号被显示了影响拼接的其他的 pre-mRNA;然而,分子的机制和导致信号的拼接的规定的生物意义仍然保持大部分未知。这里,我们报导那个表皮的生长因素(EGF ) 通过一个著名拼接管理者的 ubiquitylation 导致拼接的变化, hnRNP A1。EGF 发信号 upregulates 一个 E3 ubiquitin (Ub ) ligase 适配器,敏捷的包含域的 SOCS 盒子蛋白质 1 (SPSB1 ) ,它结合离氨酸 29 连接 polyUb 链到 hnRNP A1 上的成员 Elongin B/C-Cullin 建筑群。重要地, hnRNP A1 的 SPSB1 和 ubiquitylation 在驾驶 EGF 的房间移植有一个关键角色。机械学地,和 SR 蛋白质 kinases (SRPK ) 的激活的 hnRNP A1 的导致 EGF 的 ubiquitylation 导致拼接的 Rac1 的 upregulation isoform, Rac1b,支持房间活动性。这些调查结果解开在蛋白质 ubiquitylation 并且在 EGF/EGF 受体发信号的其他的拼接之间的新奇串音,并且在 modulating 房间移植识别新 EGF/SPSB1/hnRNP A1/Rac1 轴,它可以为癌症治疗有重要含意。 | Feng Wang Xing Fu Peng Chen Ping Wu Xiaojuan Fan Na Li Hong Zhu Ting-Ting Jia Hongbin Ji Zefeng Wang Catherine C L Wong Ronggui Hu Jingyi Hui | 2017 | Cell Research2017，27，4： | 5 |
| 2 | 韩国社会工作教育中的文化能力问题显示文摘近年来,在多元文化主义背景的影响下,社会工作的文化能力培养已成为韩国社会工作发展的当务之急。检视了韩国不同文化族群的分布,提出培养文化共融能力的理论框架,并讨论了文化能力培养在韩国社会工作发展中的有效性,以及如何在韩国社会工作教育中真正落实文化能力培养,并对社会工作的文化能力教育中潜在的影响和要点进行了讨论。 | Jun Sung Hong Charu Stokes Soo-Jung Byoun Sharlene B C L Furuto Young Sook Kim 张宇 宋洁 | 2014 | 社会工作与管理2014，14，A04： | 3 |
| 3 | Outcomes after arthroscopic repair of rotator cuff tears in the setting of mild to moderate glenohumeral osteoarthritis显示文摘BACKGROUND Rotator cuff pathology is a very common source of shoulder pain.Similarly,osteoarthritis of the glenohumeral joint can cause shoulder pain and produce similar symptoms.Surgical management can be indicated for both pathologies,however,outcomes data is limited when examining rotator cuff repair(RCR) in the setting of glenohumeral arthritis(GHOA).Thus,this study sought to determine outcomes for patients who undergo RCR in the setting of GHOA.AIM To evaluate if a relationship exists between outcomes of RCR in the setting of GHOA.METHODS This was a retrospective analysis of patients who underwent arthroscopic rotator cuff repair with concurrent glenohumeral osteoarthritis between 2010-2017.Patients were stratified based on rotator cuff tear size and glenohumeral osteoarthritis severity.Cohorts were paired 1:1 with patients without glenohumeral osteoarthritis.Patients included had a minimum two year follow-up.Rate of conversion to total shoulder arthroplasty,complication rates following initial surgery,and patient-reported outcome measures were collected.RESULTS A total of 142 patients were included.The number of patients that required total shoulder arthroplasty within two years after index surgery was low.2/71(2.8%) patients with GHOA,and 1/71(1.4%) without GHOA.Following rotator cuff repair,both groups showed favorable patientreported outcomes.CONCLUSION Patients with glenohumeral osteoarthritis who underwent arthroscopic rotator cuff repair showed comparable outcomes to patients without glenohumeral osteoarthritis. | Ian S Hong Allison J Rao Tyler L CarlLee Joshua D Meade Daniel J Hurwit Gregory Scarola David P Trofa Shadley C Schiffern Nady Hamid Patrick M Connor James E Fleischli Bryan Michael Saltzman | 2022 | World Journal of Orthopedics2022，13，7： | 2 |
| 4 | TAKI is a ubiquitin-dependent kinase of MKK and IKK 显示文摘 | Wang C Deng L Hong M | 2001 | Nature2001，412，6844： | 1 |
| 5 | An application of the electrochem- ical sulfur sensor in steelmaking 显示文摘 | Hong Y R Jin C J Li L S | 2002 | Sensors and Actuators B2002，87，： | 1 |
| 6 | Functionalization of adsorbent with different aliphatic polyamines for heavy metal ion removal: characteristics and performance显示文摘 | Liu C Bai R Hong L Liu T | 2010 | J Colloid lnterface Sci2010，345，2： | 1 |
| 7 | Urinary protein excretion in type 2 diabetes with complications 显示文摘 | Hong C Y Chia K S Ling S L | 2000 | J Diabetes Complications2000，14，5： | 1 |
| 8 | Modeling study of a flexible hub beam system with large motion and with considering the effect of shear deformation显示文摘 | You C L Hong J Z Cai G P | 2006 | Journal of Vibration and Acoustics2006，，295： | 1 |
| 9 | Stability Analysis of Networked Control Systems显示文摘 | Walsh G C Ye Hong Bushnell L | 2002 | IEEE Transactions on Control Systems Technology2002，10，3： | 1 |
| 10 | Resveratrol induces FasL-related apoptosis through Cdc42 aclivation of ASK1/JNK- dependent signaling pathway in human leukemia HL-60 cells 显示文摘 | SU J L LIN M T HONG C C | 2005 | Carcinogenesis2005，26，1： | 1 |
| 11 | A daptive characters of energy metabolism, thermo- genesis and body mass in eothenomys miletus during cold exposure and rewarming显示文摘 | WAN LONG Z JIN HONG C XIAO L | 2012 | Animal Biology2012，62，3： | 1 |
| 12 | Antibody-based protection against HIV infection by vectored immunoprophylaxis显示文摘 | Balazs A B Chen J Hong C M Rao D S Yang L Baltimore D | 2012 | Nature2012，481，7379： | 1 |
| 13 | Vehicle longitudinal brake control using variable parameter sliding control显示文摘 | Hong L Kil T C Tae S N | 2003 | Control Engineering Practice2003，11，4： | 1 |
| 14 | Fuzzy c-means clustering with spatial information for image segmenta- tion显示文摘 | KEH S C HONG L T SHARON C | 2006 | Computerized Medical Imaging and Graphics2006，30，1： | 1 |
| 15 | A fuzzy AprioriTid mining algorithm with reduced computational time显示文摘 | Hong T P Kuo C S Wang S L | 2004 | Applied Soft Computing2004，5，： | 1 |
| 16 | Determination of tomato quality by n ear infrared spectroscopy显示文摘 | Hong T L Tsou S C S Tsai S J | 1998 | Journal of Near Infrared Spectroscopy1998，6，： | 1 |
| 17 | 查看详情显示文摘 | Yan L W Duan X R Ding X T Dong J Q Yang Q W Liu Y Zou X L Liu D Q Xuan W M Chen L Y Rao J Song X M Huang Y Mao W C Wang Q M Li Q Cao Z Li B Cao J Y Lei G J Zhang J H Li X D Chen W Cheng J Cui C H Cui Z Y Deng Z C Dong Y B Feng B B Gao Q D Han X Y Hong W Y | | 0，，： | 1 |
| 18 | TAK1 is a ubiquitiondependent kinase of MKK and IKK显示文摘 | Wang C Deng L Hong M | 2001 | Nature2001，412，6844： | 1 |
| 19 | Development and evaluation of a novel loop mediated isothermal amplification method for rapid detection of sever acute respiratory syndrome coronavirus显示文摘 | Hong T C Mai Q L Cuong D V | 2004 | Journal of Clinic Microbiology2004，4，： | 1 |
| 20 | A filter-bank-based Kalman filter- ing technique for wavelet estimation and decomposition of ran- dom signals显示文摘 | Hong L Chen G Chui C K | 1998 | IEEE Transactions on Circuits and Systems-Ⅱ: Analog and Digital Signal Processing1998，45，2： | 1 |
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