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您的检索式：作者名="Honglin Che"
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| 1 | Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster显示文摘Epidemiological studies of the COVID-19 patients have suggested the male bias in outcomes of lung illness.To experimentally demonstrate the epidemiological results,we performed animal studies to infect male and female Syrian hamsters with SARS-CoV-2.Remarkably,high viral titer in nasal washings was detectable in male hamsters who presented symptoms of weight loss,weakness,piloerection,hunched back and abdominal respiration,as well as severe pneumonia,pulmonary edema,consolidation,and fibrosis.In contrast with the males,the female hamsters showed much lower shedding viral titers,moderate symptoms,and relatively mild lung pathogenesis.The obvious differences in the susceptibility to SARS-CoV-2 and severity of lung pathogenesis between male and female hamsters provided experimental evidence that SARS-CoV-2 infection and the severity of COVID-19 are associated with gender. | Lunzhi Yuan Huachen Zhu Ming Zhou Jian Ma Rirong Chen Yao Chen Liqiang Chen Kun Wu Minping Cai Junping Hong Lifeng Li Che Liu Huan Yu Yali Zhang Jia Wang Tianying Zhang Shengxiang Ge Jun Zhang Quan Yuan Yixin Chen Qiyi Tang Honglin Chen Tong Cheng Yi Guan Ningshao Xia | 2021 | Signal Transduction and Targeted Therapy2021，6，4： | 3 |
| 2 | Construction and application of bioinspired nanochannels based on two-dimensional materials显示文摘With the development of nanotechnology and materials science,bioinspired nanochannels appeared by mimicking the intelligent functions of biological ion channels.They have attracted a great deal of at-tention in recent years due to their controllable structure and tunable chemical properties.Inspired by the layered microstructure of nacre,2D layered materials as excellent matrix material of nanochannel come into our field of vision.Bionic nanochannels based on 2D materials have the advantages of facile preparation,tunable channel size and length,easy expansion,and modification,etc.Therefore,the 2D layered nanofluid system based on bionic nanochannels from 2D layered materials has great potential in biomimetic microsensors,membrane separations,energy conversion,and so on.In this paper,we focus on the construction and application of bionic nanochannels based on 2D layer materials.First,a basic understanding of nanochannels based on 2D materials is briefly introduced,we also present the property of the 2D materials and construction strategies of bionic nanochannels.Subsequently,the application of these nanochannels in responsive channels and energy conversion is discussed.The unsolved challenges and prospects of 2D materials-based nanochannels are proposed in the end. | Jinlin Hao Weijie Wang Jiawei Zhao Honglin Che Lu Chen Xin Sui | 2022 | Chinese Chemical Letters2022，33，5： | 1 |
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