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| 1 | Human umbilical cord Wharton's jelly-derived oligodendrocyte precursor-like cells for axon and myelin sheath regeneration显示文摘Human umbilical mesenchymal stem cells from Wharton's jelly of the umbilical cord were induced to differentiate into oligodendrocyte precursor-like cells in vitro. Oligodendrocyte precursor cells were transplanted into contused rat spinal cords. Immunofluorescence double staining indicated that transplanted cells survived in injured spinal cord, and differentiated into mature and immature oligodendrocyte precursor cells. Biotinylated dextran amine tracing results showed that cell transplantation promoted a higher density of the corticospinal tract in the central and caudal parts of the injured spinal cord. Luxol fast blue and toluidine blue staining showed that the volume of residual myelin was significantly increased at 1 and 2 mm rostral and caudal to the lesion epicenter after cell transplantation. Furthermore, immunofluorescence staining verified that the newly regenerated myelin sheath was derived from the central nervous system. Basso, Beattie and Bresnahan testing showed an evident behavioral recovery. These results suggest that human umbilical mesenchymal stem cell-derived oligodendrocyte precursor cells promote the regeneration of spinal axons and myelin sheaths. | Hong Chen Yan Zhang Zhijun Yang Hongtian Zhang | 2013 | Neural Regeneration Research2013，8，10： | 8 |
| 2 | Two-dimensional vanadium carbide(V2CTx) MXene as supercapacitor electrode in seawater electrolyte显示文摘In this study,two-dimensional V2CTx MXene has been prepared by selectively etching Al layers from V2 AlC MAX phase by NaF+HCl etching at 90℃for 72 h and its performance as supercapacitor(SC)electrode were tested using simulating seawater as electrolyte.V2CTx MXene-based electrodes shows a good capacitance of 181.1 F/g,which is in accordance with the volumetric specific capacitance of 317.8 F/cm^3,and with 89.1%capacitance retention even after 5000 cycle.Compared with other MXenes,V2CTx have better electrochemical performance as SC electrode.This work provides an innovative strategy to apply V2CTx MXene as SC electrode in safety and effective seawater electrolyte. | Hongtian He Qixun Xia Bingxin Wang Libo Wang Qianku Hu Aiguo Zhou | 2020 | Chinese Chemical Letters2020，31，4： | 6 |
| 3 | SUBJECTIVE TINNITUS AS FIRST PRESENTATION IN A PATIENT WITH METASTATIC LUNG CANCER IN TEMPORAL BONE-A CASE REPORT显示文摘Metastasis of lung cancer to the temporal bone is a very rare disease and subjective tinnitus as the presenting symptom in these patients is even rarer. Here we report a case in which a 42-year-old male presented with subjective tinnitus of three months, with no pulmonary disease symptoms. Pure tone audiometry indicated moderate conductive deafness in left ear with an air-bone gap of 21.3 dB. HRCT temporal bone scanning indicated high-density shadows in the left epitympanic cavity, sinus tympani and mastoid cavity. Chronic otitis media with cholesteatoma was suspected and surgical treatment recommended. However, preoperative chest x- ray revealed high- density millet lesions scattered widely in both lungs. HRCT lung scanning confirmed the lungs lesions and indicated lung cancer. In order to determine correlations between the temporal bone and pulmonary lesions, a CT- guided trans- mastoid aspiration biopsy and immunohistochemical study were conducted, which confirmed that the temporal bone lesion was metastatic from the lungs. The patient was given a series of chemotherapy immediately and his tinnitus significantly improved after three months of treatment, with full recovery of his hearing and complete resolution of shadows in the mastoid cavity. Unfortunately, he subsequently developed multiple bone metastases in the 9th month and cerebral metastasis in the 18th month. Multiple organ failure resulted in death in 2.5 years. | ZHANG Jing WANG Hongtian JIA Jingjie XIAO Yueyong SHI Huaiyin YANG Weiyan | 2013 | Journal of Otology2013，8，2： | 2 |
| 4 | Folic Acid Supplementation During Early Pregnancy and the Risk of Gestational Hypertension and Preeclampsia显示文摘 | Zhiwen Li Rongwei Ye Le Zhang Hongtian Li Jianmeng Liu Aiguo Ren | 2013 | Hypertension2013，，4： | 1 |
| 5 | Amyloidosis cutis dyschromica 显示文摘 | Jianjun Q Hong F Hongtian Y | 2012 | Or- pha J Rare Dis2012，7，1： | 1 |
| 6 | Skew t Distribution-Based Nonlinear Filter with Asymmetric Measurement Noise Using Variational Bayesian Inference显示文摘This paper is focused on the state estimation problem for nonlinear systems with unknown statistics of measurement noise.Based on the cubature Kalman filter,we propose a new nonlinear filtering algorithm that employs a skew t distribution to characterize the asymmetry of the measurement noise.The system states and the statistics of skew t noise distribution,including the shape matrix,the scale matrix,and the degree of freedom(DOF)are estimated jointly by employing variational Bayesian(VB)inference.The proposed method is validated in a target tracking example.Results of the simulation indicate that the proposed nonlinear filter can perform satisfactorily in the presence of unknown statistics of measurement noise and outperform than the existing state-of-the-art nonlinear filters. | Chen Xu Yawen Mao Hongtian Chen Hongfeng Tao Fei Liu | 2022 | Computer Modeling in Engineering & Sciences2022，，4： | 1 |
| 7 | A new polystyrene-TiO2 nano composite film and its photocatalytic degradation显示文摘 | LING Zan LI Hongtian ZHONG Shi liu | | 0，，： | 1 |
| 8 | Risk Factors and Pregnancy Outcome in Women with a History of Cesarean Section Complicated by Placenta Accreta显示文摘Objective:To explore the risk factors and pregnancy outcomes in women with a history of cesarean section complicated by placenta accreta(PA).Methods:This case-control study included clinical data from singleton mothers with a history of cesarean section in 11 public tertiary hospitals in seven provinces of China between January 2017 and December 2017.According to the intraoperative findings after delivery,the study population was divided into PA and non-PA groups.We compared the pregnancy outcomes between the two groups,used multivariate logistic regression to analyze the risk factors for placental accreta.Results:For this study we included 11,074 pregnant women with a history of cesarean section;and of these,869 cases were in the PA group and 10,205 cases were in the non-PA group.Compared with the non-PA group,the probability of postpartum hemorrhage(236/10,205,2.31%vs.283/869,32.57%),severe postpartum hemorrhage(89/10,205,0.87%vs.186/869,21.75%),diffuse intravascular coagulation(3/10,205,0.03%vs.4/869,0.46%),puerperal infection(33/10,205,0.32%vs.12/869,1.38%),intraoperative bladder injury(1/10,205,0.01%vs.16/869,1.84%),hysterectomy(130/10,205,1.27%vs.59/869,6.79%),and blood transfusion(328/10,205,3.21%vs.231/869,26.58%)was significantly increased in the PA group(P<0.05).At the same time,the neonatal birth weight 3250.00(2950.00–3520.00)g vs.2920.00(2530.00–3250.00)g),the probability of neonatal comorbidities(245/10,205,2.40%vs.61/869,7.02%),and the rate of neonatal intensive care unit admission(817/10,205,8.01%vs.210/869,24.17%)also increased significantly(P<0.05).Weight(odds ratio)(OR)=1.03,95%confidence interval(CI):1.01–1.05)),parity(OR=1.18,95%CI:1.03–1.34),number of miscarriages(OR=1.31,95%CI:1.17–1.47),number of previous cesarean sections(OR=2.57,95%CI:2.02–3.26),history of premature rupture of membrane(OR=1.61,95%CI:1.32–1.96),previous cesarean-section transverse incisions(OR=1.38,95%CI:1.12–1.69),history of placenta previa(OR=2.44,95%CI:1.50–3.96),and the combination of prenatal hemorrhage(OR=9.95,95%CI:8.42–11.75)and placenta previa(OR=91.74,95%CI:74.11–113.56)were all independent risk factors for PA.Conclusion:There was an increased risk of adverse outcomes in pregnancies complicated by PA in women with a history of cesarean section,and this required close clinical attention.Weight before pregnancy,parity,number of miscarriages,number of previous cesarean sections,history of premature rupture of membranes,past transverse incisions in cesarean sections,a history of placenta previa,prenatal hemorrhage,and placenta previa were independent risk factors for pregnancies complicated with PA in women with a history of cesarean section.These independent risk factors showed a high value in predicting the risk for placentab accreta in pregnancies of women with a history of cesarean section. | Yingyu Liang Lizi Zhang Shilei Bi Jingsi Chen Shanshan Zeng Lijun Huang Yulian Li Minshan Huang Hu Tan Jinping Jia Suiwen Wen Zhijian Wang Yinli Cao Shaoshuai Wang Xiaoyan Xu Ling Feng Xianlan Zhao Yangyu Zhao Qiying Zhu Hongbo Qi Lanzhen Zhang Hongtian Li Lili Du Dunjin Chen | 2022 | Maternal-Fetal Medicine2022，4，3： | 1 |
| 9 | IL-6 promotes the expression of vascular endothelial growth factor through the p38 signalling pathway in hypertrophied adenoids in children显示文摘 | Hongtian Wang Jing Bai Jing Zhang Wu Yang Kejun Zuo Huabin Li | 2012 | International Journal of Pediatric Otorhinolaryngology2012，，： | 1 |
| 10 | Folic Acid Supplementation During Early Pregnancy and the Risk of Gestational Hypertension and Preeclampsia显示文摘 | Zhiwen Li Rongwei Ye Le Zhang Hongtian Li Jianmeng Liu Aiguo Ren | 2013 | Hypertension2013，，4： | 1 |
| 11 | Sigma-Mixed Unscented Kalman Filter-Based Fault Detection for Traction Systems in High-Speed Trains显示文摘Fault detection(FD)for traction systems is one of the active topics in the railway and academia because it is the initial step for the running reliability and safety of high-speed trains.Heterogeneity of data and complexity of systems have brought new challenges to the traditional FD methods.For addressing these challenges,this paper designs an FD algorithm based on the improved unscented Kalman filter(UKF)with consideration of performance degradation.It is derived by incorporating a degradation process into the state-space model.The network topology of traction systems is taken into consideration for improving the performance of state estimation.We first obtain the mixture distribution by the mixture of sigma points in UKF.Then,the Lévy process with jump points is introduced to construct the degradation model.Finally,the moving average interstate standard deviation(MAISD)is designed for detecting faults.Verifying the proposed methods via a traction systems in a certain type of trains obtains satisfactory results. | CHENG Chao WANG Weijun MENG Xiangxi SHAO Haidong CHEN Hongtian | 2023 | Chinese Journal of Electronics2023，32，5： | 0 |
| 12 | A series of simple curcumin-derived colorimetric and fluorescent probes for ratiometric-pH sensing and cell imaging显示文摘Colorimetric and fluorescent probes have emerged as a potent tool for pH sensing due to easy operation and high sensitivity.However,most of the existing bimodal probes require complicated synthesis,which greatly limits their wide applications.Herein,a simple fluorescent dye(called BFCUR)featuring a D-π-A-π-D conjugated system was developed from the natural polyphenol curcumin(CUR).BFCUR exhibited significant red-shift in UV absorption and fluorescence emission as pH increased because of the deprotonation of the phenolic hydroxyl groups,which resulted in the enhanced intramolecular charge transfer(ICT).The ratiometric pH detection of BFCUR was achieved with remarkable accuracy by monitoring both the absorbance ratio A;/A;and the fluorescence intensity ratio I;/I;under various pH values.In addition,the clear color changes of BFCUR under different pH conditions were visible,which enabled BFCUR to be used in test strips for rapid,visual pH detection.Moreover,BFCUR exhibited low cytotoxicity,and was successfully applied for intracellular pH detection,where the fluorescence intensity was linearly related to pH value.This study highlighted the great potential of CUR-derived BFCUR as colorimetric and fluorescent probes for ratiometric-pH sensing and cell imaging. | Guangjie Song Di Jiang Lei Wang Xiangzhong Sun Hongtian Liu Yanqing Tian Meiwan Chen | 2022 | Chinese Chemical Letters2022，33，1： | 0 |
| 13 | NEW MECHANISM OF LIMITED-SLIP DIFFERENTIAL显示文摘NEWMECHANISMOFLIMITED-SLIPDIFFERENTIAL￥ZhangShemin;LuoHongtian(Xi'anJiaotongUniversity)Abstract:Accordingtopropertyrequiremen... | Zhang Shemin Luo Hongtian(Xi’an Jiaotong University) | 1994 | Chinese Journal of Mechanical Engineering1994，7，2： | 0 |
| 14 | Finite-Time Synchronization of Complex Networks With Intermittent Couplings and Neutral-Type Delays显示文摘Dear Editor, This letter focuses on the finite-time synchronization(FTS) of neutral-type complex networks with intermittent couplings. Different from most of the existing references concerning neutral-type systems,a delay-independent dynamical event-triggering controller is considered, operating the same way as the intermittent coupling and excluding the Zeno behavior naturally. | Engang Tian Yi Zou Hongtian Chen | 2023 | IEEE/CAA Journal of Automatica Sinica2023，10，10： | 0 |
| 15 | Dielectric temperature stability and energy storage performance of NBT-based lead-free ceramics for Y9P capacitors显示文摘In this work,novel(1−x)(0.75Na_(0.5)Bi_(0.5)TiO_(3))-0.25Sr(Zr_(0.2)Sn_(0.2)Hf_(0.2)Ti_(0.2)Nb_(0.2))O_(3)-xNaNbO_(3)(NBT-SZSHTN-xNN,x=0.1,0.15,0.2,0.25)ceramics were fabricated.The influence of co-doping of NN and high entropy perovskite oxide(SZSHTN)on the phase structure,microstructure and dielectric properties of NBT-based lead-free ceramics was investigated.Dense microstructure with a grain size of~5μm is observed.When x=0.25,a wide dielectric temperature stable range of−35.4-224.3℃ with a low temperature coefficient of capacitance of<10%is achieved,fulfilling the industry standard of Y9P specification.Furthermore,excellent energy storage performance with recoverable energy density of 2.4 J/cm^(3),discharge efficiency of 71%,power density of 25.495 MW/cm^(3) and discharge rate<200 ns are simultaneously obtained,which shows great potential for high temperature capacitor applications. | Hongtian Li Shiyu Zhou Jianwei Zhao Tingnan Yan Yuxiao Du Huanfu Zhou Yongping Pu Dawei Wang | 2023 | Journal of Advanced Dielectrics2023，13，1： | 0 |
| 16 | Development and application of novel high‐efficiency composite ultrafine cement grouts for roadway in fractured surrounding rocks显示文摘The fractured surrounding rocks of roadways pose major challenges to safe mining.Grouting has often been used to reinforce the surrounding rocks to mitigate the safety risks associated with fractured rocks.The aim of this study is to develop highly efficient composite ultrafine cement(CUC)grouts to reinforce the roadway in fractured surrounding rocks.The materials used are ultrafine cement(UC),ultrafine fly ash(UF),ultrafine slag(US),and additives(superplasticizer[SUP],aluminate ultrafine expansion agent[AUA],gypsum,and retarder).The fluidity,bleeding,shrinkage,setting time,chemical composition,microstructure,degree of hydration,and mechanical property of grouting materials were evaluated in this study.Also,a suitable and effective CUC grout mixture was used to reinforce the roadway in the fractured surrounding rock.The results have shown that the addition of UF and US reduces the plastic viscosity of CUC,and the best fluidity can be obtained by adding 40%UF and 10%US.Since UC and UF particles are small,the pozzolanic effect of UF promotes the hydration reaction,which is conductive to the stability of CUC grouts.In addition,fine particles of UC,UF,and US can effectively fill the pores,while the volumetric expansion of AUA and gypsum decreases the pores and thus affects the microstructure of the solidified grout.The compressive test results have shown that the addition of specific amounts of UF and US can ameliorate the mechanical properties of CUC grouts.Finally,the CUC22‐8 grout was used to reinforce the No.20322 belt roadway.The results of numerical simulation and field monitoring have indicated that grouting can efficaciously reinforce the surrounding rock of the roadway.In this research,high‐performance CUC grouts were developed for surrounding rock reinforcement of underground engineering by utilizing UC and some additives. | Maolin Tian Shaojie Chen Lijun Han Hongtian Xiao | 2024 | Deep Underground Science and Engineering2024，3，1： | 0 |
| 17 | Reinforcement Learning in Process Industries:Review and Perspective显示文摘This survey paper provides a review and perspective on intermediate and advanced reinforcement learning(RL)techniques in process industries. It offers a holistic approach by covering all levels of the process control hierarchy. The survey paper presents a comprehensive overview of RL algorithms,including fundamental concepts like Markov decision processes and different approaches to RL, such as value-based, policy-based, and actor-critic methods, while also discussing the relationship between classical control and RL. It further reviews the wide-ranging applications of RL in process industries, such as soft sensors, low-level control, high-level control, distributed process control, fault detection and fault tolerant control, optimization,planning, scheduling, and supply chain. The survey paper discusses the limitations and advantages, trends and new applications, and opportunities and future prospects for RL in process industries. Moreover, it highlights the need for a holistic approach in complex systems due to the growing importance of digitalization in the process industries. | Oguzhan Dogru Junyao Xie Om Prakash Ranjith Chiplunkar Jansen Soesanto Hongtian Chen Kirubakaran Velswamy Fadi Ibrahim Biao Huang | 2024 | IEEE/CAA Journal of Automatica Sinica2024，11，2： | 0 |
| 18 | Analysis of the personalized treatment and the relevant prognostic factors in children with medulloblastoma显示文摘Purpose:The present study summarized cases of children(n=32)with medulloblastoma(MB)who were treated using stratified therapy based on risk grading and also discussed the factors affecting prognosis.Methods:According to the risk stratification criteria,the cases were divided into the following four risk groups:low,standard,high,and very high.The 5-year overall survival(OS)and progression-free survival(PFS)rates were summarized.Further,the effects on the prognosis of tumor size,tumor stage,degree of resection,treatment mode,metastatic recurrence,molecular typing,and risk stratification were analyzed.Results:In the present study,following surgery,3 cases abandoned radiotherapy(RT)and chemotherapy(CHT),7 cases(<3 years of age)received only CHT,and 22 cases received combined RT and CHT.Total and near-total tumor resections were performed in 29 cases(90.6%).Subtotal resections were performed in 3 cases,and there were no surgery-related deaths.The average follow-up duration was 47 months.The average 5-year PFS and OS rates were 57.3%±7.2%and 68.7%±8.6%,respectively.The OS and PFS rates were significantly correlated with tumor-risk stratification,molecular staging,tumor stage,treatment mode,and recurrence after surgery(p<0.01).The degree of tumor resection,pathological type,and the presence of preoperative implantation were secondary factors affecting the prognosis(p<0.05).Age was correlated with the PFS rate.There was no correlation between age/tumor location/tumor size and prognosis(p>0.05).Favorable prognostic factors in the low-and standard-risk groups were stage M0,wingless-type MB,postoperative RT combined with CHT,no postoperative recurrence,age≥3 years,and total tumor resection.Conclusions:Personalized treatment strategies based on the risk stratification of MB and postoperative stratified comprehensive treatment could help improve the prognosis for MB. | LIHUA CHEN HONGTIAN ZHANG YONG XIA KAI SUN WENJIN CHEN RUXIANG XU | 2023 | BIOCELL2023，47，5： | 0 |
| 19 | Parameters of Exterior Ballistic Feature Points Extraction in Radar Measurement Data by EMD显示文摘The problem of measuring exterior ballistic feature points is always difficult to solve and it is essentiale on exterior ballistic measurement.By analysis of radar reflection characteristics and non-stationary echo signals of exterior ballistic feature points,the echo data of exterior ballistic feature points is measured by using the continuous wave radar.The parameters of feature points are extracted by the empirical mode decomposition method(EMD)of Hilbert-Huang transform(HHT)spectrum analysis technique.The radar echo signal model and EMD extraction model are established to analyze the exterior ballistic mutation point detection and EMD extraction method of aliasing echo signal.Typical feature point parameters of exterior ballistic in rocket flight tests are carried out and the effectiveness of the method is verified.A new method of measuring the parameters of exterior ballistic feature point is therefore presented. | Wanjun Zhang Kailin Wang Xiaoying Wu Guohui Li Hongtian Liu | 2018 | Journal of Beijing Institute of Technology2018，27，4： | 0 |
| 20 | Microfluidics embedded with microelectrodes for electrostimulation of neural stem cells proliferation显示文摘The regeneration of the injured nerve and recovery of its function have brought attention in the medical field. Electrical stimulation(ES) can enhance the cellular biological behavior and has been widely studied in the treatment of neurological diseases. Microfluidic technology can provide a cell culture platform with the well-controlled environment. Here a novel microfluidic/microelectrode composite microdevice was developed by embedding the microelectrodes to the microfluidic platform, in which microfluidics provided a controlled cell culture platform, and ES promoted the NSCs proliferation. We performed ES on rat neural stem cells(NSCs) to observe the effect on their growth, differentiation, proliferation, and preliminary explored the ES influence on cells in vitro. The results of immunofluorescence showed that ES had no significant effect on the NSCs specific expression, and the NSCs specific expression reached 98.9%± 0.4% after three days of ES. In addition, ES significantly promoted cell growth and the cell proliferation rate reached 49.41%. To conclude, the microfluidic/microelectrode composite microdevice can play a positive role in the nerve injury repair and fundamental research of neurological diseases. | Qian Li Bodong Kang Libin Wang Tao Chen Yu Zhao Shilun Feng Rongjing Li Hongtian Zhang | 2022 | Chinese Chemical Letters2022，33，3： | 0 |
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