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| 1 | Re-Os Isotopic Dating of a W-Be Polymetallic Deposit in the Southern Qinling Region, China显示文摘Objective In recent years,a series of tungsten prospecting breakthroughs have been made in the southern Qinling Mountains.Especially,a new deposit type with a scheelite-beryl-molybdenite assemblage in the Zhen’an area of Shaanxi Province was firstly discovered.This deposit is currently in a detailed investigation stage,and no | DAI Hongzhang WANG Denghong WANG Chenghui HUANG Fan | 2018 | Acta Geologica Sinica(English Edition)2018，92，1： | 4 |
| 2 | Effect of the pore length and orientation upon the electrochemical capacitive performance of ordered mesoporous carbons显示文摘By utilizing hard template method to adjust the mesopore length, and alkali activation to generate micro pores, two hierarchical porous carbons(HPCs) were prepared. With controlling of their mesopore length and the activation conditions, the complex system composed by HPCs and electrolyte was simplified and the effect of mesopore length on the performance of HPCs as electrodes in supercapacitors was investi gated. It is found that with the mesopore length getting smaller, the ordered area gets smaller and th aggregation occurs, which is caused by the high surface energy of small grains. HPC with long pore(HPCL) exhibits a donut-like morphology with well-defined ordered mesopores and a regular orientation while in HPC with short pores(HPCS), short mesopores are only orderly distributed in small regions Longer ordered channels form unobstructed ways for ions transport in the particles while shorter chan nels, only orderly distributed in small areas, results in blocked paths, which may hinder the electrolyt ions transport. Due to the unobstructed structure, HPCL exhibits good rate capability with a capacitanc retention rate over 86% as current density increasing from 50 m A/g to 1000 m A/g. The specific capaci tance of HPCL derived from the cyclic voltammetry test at 10 m V/s is up to 201.72 F/g, while the specifi capacitance of HPCS is only 193.65 F/g. | Anran Huang Jingwang Yan Hongzhang Zhang Xianfeng Li Huamin Zhang | 2017 | Journal of Energy Chemistry2017，26，1： | 2 |
| 3 | Comprehensive profiling of Lingzhihuang capsule by liquid chromatography coupled with mass spectrometry-based molecular networking and target prediction显示文摘Objective:Lingzhihuang capsule(LZHC)is a natural product that consists of 10 commonly used medicinal plants,and it is used in traditional Chinese medicine to promote people’s overall health.Previously,LZHC was successfully used as adjuvant therapy for treating patients with cancer.However,the chemical constituents of LZHC and their potential biological functions remain unclear.The aim of this study is to investigate the major bioactive compounds in LZHC and predict their pharmacological targets.Methods:The LZHC constituents were putatively identified by ultra-high performance liquid chromatography coupled with timeof-flight mass spectrometry combined with mass spectrometry-based molecular networking.The targets were predicted using SwissTargetPrediction software,and the associated gene ontology and Kyoto encyclopedia of genes and genomes pathways were analyzed using the Database for Annotation,Visualization,and Integrated Discovery.The mass spectrometry-based molecular network and compound-target-pathway network were constructed using Cytoscape 3.8.0 software.Results:We putatively identified 94 compounds of LZHC by mass spectrometry-based molecular networking,including triterpene(the main structural type)and other clusters(ie,flavonoids and organic acids).Our results suggested that multiple pivotal targets were regulated by LZHC,including tumor necrosis factor,nitric oxide synthase 2,glucocorticoid receptor,estrogen receptor,3-oxo-5-alpha-steroid 4-dehydrogenase 2,prostaglandin e2 receptor ep4 subtype,estrogen receptor beta,phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform,mitogen-activated protein kinase 3,and racalpha serine,which are related to signal transduction,positive regulation of transcription from RNA polymerase II promoters,oxidation-reduction processes,inflammatory responses,and other biological processes.Functional annotation of those targets suggested that several signaling pathways may be regulated by LZHC,such as cancer-related proteoglycans,the PI3K-Aktsignaling pathway,and the cAMP-signaling pathway.Conclusions:Our findings reveal the chemical constituents of LZHC and provided scientific support for the efficacy of LZHC in terms of immune regulation,anti-aging,and tumor suppression. | Mengliang Huang Sijia Yu Qing Shao Hao Liu Yingchao Wang Hongzhang Chen Yansheng Huang Yi Wang | 2022 | Acupuncture and Herbal Medicine2022，2，1： | 2 |
| 4 | Smad2/3 Is Involved in Growth Inhibition of Mouse Embryonic Palate Mesenchymal Cells Induced by All-trans Retinoic Acid显示文摘 | Miao Wang Hongzhang Huang Yiyang Chen | 2009 | Birth Defects Res A Clin Mol teratol2009，85，9： | 1 |
| 5 | Polycomb group protein EZH2‐mediated E‐cadherin repression promotes metastasis of oral tongue squamous cell carcinoma显示文摘 | Cheng Wang Xiqiang Liu Zujian Chen Hongzhang Huang Yi Jin Antonia Kolokythas Anxun Wang Yang Dai David T.W. Wong Xiaofeng Zhou | 2011 | Mol Carcinog2011，，3： | 1 |
| 6 | Cellular antioxidant activities of polyphenols isolated from Eucalyptus leaves ( Eucalyptus grandis×Eucalyptus urophylla GL9 )显示文摘 | Yunjiao Chen Junjiang Wang Yangwen Ou Hongzhang Chen Suyao Xiao Guo Liu Yong Cao Qingrong Huang | 2013 | Journal of Functional Foods2013，，： | 1 |
| 7 | Optimization of liquid chromatographic method for the separation of nine hydrophilic and hydrophobic components in Salviae miltiorrhizae Radix et Rhizoma (Danshen) using microemulsion as eluent 显示文摘 | HUANG Hongzhang XUAN Xueyi XU Liyuan | 2014 | J Chromatogr B2014，，： | 1 |
| 8 | A novel radical surgery maintaining or improving quality of life in early stage tongue cancer显示文摘 | Bin Zhang Huang Hongzhang Pan Chaobin Wang Jianguang Xu Jianghui Chen Weiliang | 2008 | 中国口腔颌面外科杂志2008，6，B05： | 0 |
| 9 | The anti-proliferative activity and cellular antioxidant activity of oenothein B and its content in different Eucalyptus species and region显示文摘The leaves of Eucalyptus are abundant in natural resources as a novel potential antioxidant and have broad market prospect.Four of characteristic hydrolysable tannins from Eucalyptus leaves have been demonstrated great application potential as natural antioxidants in our previous research.In this study,the bioactive activities of another hydrolysable tannin isolated and identified as oenothein B(OEB)were evaluated.Content of bioactive compound(hydrolysable tannin)from different Eucalyptus species and regions in southern China were investigated.The results showed that OEB not only exerted anti-proliferative activity against HepG2 cell,but also showed higher cellular antioxidant activity than some common antioxidants.Generally,content of characteristic hydrolysable tannins decreased in the order of OEB>tellimagrandin I(T1)>pedunculagin>gemin D>pentagalloyl glucose(PGG).E.grandis×E.urophylla GL9 and E.urophylla×E.grandis could be recommended as new natural sources to exploit hydrolysable tannins because of high content,widely plantation and strong adaptability.This study supplied first insight on introduction of high cellular antioxidant activity of OEB and selecting the species and region to exploit natural antioxidants.It will promote the increasing of economic value of Eucalyptus. | Yunjiao Chen Qiao Qin Hongzhang Chen Qingrong Huang Mingyue Song Suyao Xiao Longbipei Cao Yong Cao | 2023 | Journal of Future Foods2023，3，4： | 0 |
| 10 | BONDING PROCESS AND MECHANISM OF ALUMINUM ALLOY BONDING SHEET显示文摘1INTRODUCTIONThethreelayeraluminumaloybondingsheet(AlSi/AlMn/AlSi)asoneofthekeymaterialsforaluminumheatexchangershasawidea... | Lingyun, Wang Hongzhang, Zhou Guangjie, Huang Zhenghong, Liu | 1998 | 中国有色金属学会会刊:英文版1998，8，3： | 0 |
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