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| 1 | Current perspectives on in vitro maturation and its effects on oocyte genetic and epigenetic profiles显示文摘In vitro maturation(IVM), the maturation in culture of immature oocytes, has been used in clinic for more than 20 years.Although IVM has the specific advantages of low cost and minor side effects over controlled ovarian stimulation, the prevalence of IVM is less than 1% of routine in vitro fertilization and embryo transfer techniques in many reproductive centers. In this review, we searched the MEDLINE database for all full texts and/or abstract articles published in English with content related to oocyte IVM mainly between 2000 and 2016. Many different aspects of the IVM method may influence oocyte potential,including priming, gonadotrophin, growth factors, and culture times. The culture conditions of IVM result in alterations in the oocyte or cumulus cell transcriptome that are not observed under in vivo culture conditions. Additionally, epigenetic modifications, such as DNA methylation or acetylation, are also different between in vitro and in vivo cultured oocytes. In sum,current IVM technique is still not popular and requires more systematic and intensive research to improve its effects and applications. This review will help point our problems, supply evidence or clues for future improving IVM technique, thus assist patients for fertility treatment or preservation as an additional option. | Cuiling Lu Yaoyao Zhang Xiaoying Zheng Xueling Song Rui Yang Jie Yan Huailiang Feng Jie Qiao | 2018 | Science China(Life Sciences)2018，61，6： | 10 |
| 2 | Femtosecond laser 3D fabrication of whispering-gallerymode microcavities显示文摘Whispering-gallery-mode(WGM) microcavities with high-quality factors and small volumes have attracted intense interests in the past decades because of their potential applications in various research fields such as quantum information, sensing, and optoelectronics. This leads to rapid advance in a variety of processing technologies that can create high-quality WGM micro-cavities. Due to the unique characteristics of femtosecond laser pulses with high peak intensity and ultrashort pulse duration, femtosecond laser shows the ability to carry out ultrahigh precision micromachining of a variety of transparent materials through nonlinear multiphoton absorption and tunneling ionization. This review paper describes the basic principle of femtosecond laser direct writing, and presents an overview of recent progress concerning femtosecond laser three-dimensional(3D) fabrications of optical WGM microcavities, which include the advances in the fabrications of passive and active WGMs microcavities in a variety of materials such as polymer, glass and crystals, as well as in processing the integrated WGM-microcavity device. Lastly, a summary of this dynamic field with a future perspective is given. | XU HuaiLiang SUN HongBo | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，11： | 5 |
| 3 | Complex sources of air-soil-water pollution processes in the Miyun reservoir region显示文摘The comprehensive impact of atmospheric dry deposition and wet deposition and the pollution sources of farmlands, mining areas, and towns along the Baihe River on the water quality of Miyun reservoir is investigated from the angle of the complex sources of air-soil-water pollution processes, in the context of the 1990-2001 precipitation chemical data at Shangdianzi station--a WMO regional background air pollution monitoring station 15 km far from the Miyun reservoir, in conjunction with the atmospheric dry deposition and wet deposition data of the 2002-2003 Beijing City Air Pollution Observation Field Experiment (BECAPEX). Analysis results suggest that the major ions in precipitation in the Miyun reservoir region in this period were SO, NO, NH and Ca2+; wet acid deposition quantity of Miyun reservoir in the summer half year (April to September) was greater than the quantity in the winter half year (October to March), and the annual wet acid deposition in the reservoir exhibited a rising trend with the mean 1038.45 t, the maximum 1766.31 t occurred in 1996, and the minimum 604.02 t in 1994; the long-term averaged pH of atmospheric precipitation in the Miyun reservoir region was 5.20, i.e. weakly acidic, and the interannual variation of pH values displayed a falling trend. pH values of water body at various depths in the Miyun reservoir were all greater than 7.0, but they exhibited vertical and horizontal nonhomogeneity, and at the same region pH decreased vertically with depth; the 2002 and 2003 annual dustfalls in the Miyun reservoir were 13513.08 t and 3577.64 t, respectively, and the spring dustfall was the number one in a year, accounting for the 61.91% and 44.56% of the annual totals of 2002 and 2003, respectively. Because the atmospheric dry deposition and wet depositions contain multiple types heavy metal elements and harmful elements, they to some extent exacerbated the eutrophication, acidification and potential heavy metal pollution of the reservoir water. The above comprehensive analysis results reveal the complex source characters of the air-soil-water pollution process and the multi-sphere interaction effect. Besides, summer (rainy season) is a season when local soil pollutants enter the water system of reservoir after being washed out by torrential rain or heavy precipitation, which starts the air-soil- water chaining pollution processes, and results in the water pollution of rivers and reservoirs. It is found from the statistical analysis in this paper that the water pollution of Miyun reservoir was correlated with the rain wash-out and confluent flow in the peripheral and upstream local region of the reservoir, and the pollutant concentration of the reservoir water was significantly correlated with the upstream local region precipitation. Those correlation characters reveal the effect of the air-soil-water multi-spheric interaction of reservoir water pollution process. This paper presents the point of view of the complex source analysis of reservoir water pollution and a technical approach for tracing the spatial distribution of the upstream pollution source of the water systems of reservoir. | YANG Dongzhen, XU Xiangde, LIU Xiaoduan, XU Qing, DING Guoan, CHENG Xinghong, CHEN Huailiang, ZHOU Huaigang, WANG Zhenfa, WANG Wenyan Key Laboratory of Atmospheric Chemistry, Center for Atmosphere Watch and Services, Chinese Academy of Meteorological Sciences, CMA, Beijing 100081, China Key Laboratory of Meteorological Disasters, CAMS, Beijing 100081, China National Center for Geological Testing, Beijing 100037, China Meteorological Bureau of Henan Province, Zhenzhou 450000, China Shangdianzi Background Atmospheric Pollution Observation Station, Miyun County, Beijing 101507, China | 2005 | Science China Earth Sciences2005，48，z2： | 4 |
| 4 | Completion and stimulation trends in North American unconventional plays and resulting impact on well productivity显示文摘过去十年,非常规油气勘探开发在全球范围内大幅扩张。水平钻井和多级水力压裂技术也在不断地发展和创新,使得超长水平井成为可能。同时,因为压裂强度不断增加,作业者可以最大限度地提高储层接触面积和对储层的改造体积(SRV)。然而,完井优化方面的挑战仍然存在,作业者持续不断地尝试和试验各种完井与增产参数组合,以确保非常规油气藏开发的经济可行性。优选最佳的完井与增产参数组合是一项非常关键的任务,应结合油气田的具体储层特征进行优化。本文总结了2014—2020年间北美9个主要非常规油气藏的压裂增产趋势,包括Marcellus,Haynesville,Barnett,Utica,Bone Spring,Bakken,Wolfcamp Midland,Eagle Ford,Scoop/Stack。分析了各油气田几个关键的完井和增产参数的整体趋势,同时还评估了单个参数(如水平段压裂长度、支撑剂强度、段间距等)对井产能的影响。然后对比分析相应的初始井产量(90天平均初始产量),评估各个参数对产能的影响,从而确定每个完井参数的最佳范围,以实现产能最优化。 | Roman Galchenko Qing Liu Yan Gao Yu Liu David He Josh Zhang Huailiang Liu Xiaohua Ke | 2021 | 钻探工程2021，48，10： | 3 |
| 5 | Femtosecond laser processing of microcavity lasers显示文摘在这份报纸,我们由 femtosecond 激光处理在象聚合物和蛋白质那样的软材料考察了功能的 microcavity 激光的制造。有激光染料的高质量的(Q) microdisks (玫瑰精 B, RhB ) 充当获得媒介被制作放射激光的那生产 whispering-gallery-mode (WGM ) 输出。我们也在房间温度在使变形的螺线 microcavity 与低放射激光阀值获得了单向性的放射激光的输出。Photonic 分子(下午) microlasers 被准备调查相互作用和不同的洞的联合效果,并且在二个磁盘之间的距离在放射激光的行为起一个重要作用,这被发现。单个模式的放射激光通过游标效果从叠的下午 microlaser 被认识到。而且,我们采用了 biocompatible 材料,是的做 RhB 的蛋白质主人材料并且制作一三维(3D ) WGM microlaser,它在空和水的环境中两个都操作了很好。察觉到对 Na 24 集中因此被调查。我们与不同材料制作 high-Q microlasers 的结果揭示 femtosecond 激光在综合 optoelectronic 的区域处理的潜在的应用并且超离频敏感察觉到简历的设备。 | Xuepeng ZHAN Huailiang XU Hongbo SUN | 2016 | Frontiers of Optoelectronics2016，9，3： | 1 |
| 6 | Topical transport of hydrophilic compounds using water-in-oil nanoemulsions 显示文摘 | Huailiang WU Chandrasekharan Ramaehandran Norman D Weiner | 2001 | Int J Pharm2001，220，： | 1 |
| 7 | Femtosecond laser ionization and fragmentation of molecules for environmental sensing显示文摘 | Huailiang Xu Ya Cheng See‐Leang Chin Hong‐Bo Sun | 2015 | Laser & Photonics Reviews2015，，3： | 1 |
| 8 | Decay Properties of Er3+ Ions in Er3+:YAG and Er3+:YAlO3 显示文摘 | Huailiang Xu Lige Zhou Zhenwen Dai | 2002 | Physica B2002，，324： | 1 |
| 9 | Dynamics of Visible-to-ultraviolet Upconversion in YAlO3: 1% Er3+显示文摘 | Huailiang Xu Zhankui Jiang | 2003 | Chemical Physics2003，287，： | 1 |
| 10 | Review:Coincidence Momentum Imaging:Principle and Application in Molecular Reaction Dynamics显示文摘Coincidence Momentum Imaging(CMI) is a powerful imaging technique that can determine the full momentum vectors of all particles released from a single parent molecule in coincidence and thus provide detailed information on transient molecular structures.So far,the CMI technique has been extensively employed for investigating a variety of molecular reaction dynamics induced,e.g.,by particle collisions,intense laser fields and synchrotron radiation.In this article,we first introduce the principle of the CMI technique,which is followed by several typical experimental designs of the CMI systems realizing the coincidence momentum detections.We then present representative examples of studying molecular reaction dynamics using the CMI technique. | Li Zhang Huailiang Xu | 2018 | Journal of Harbin Institute of Technology(New Series)2018，25，4： | 1 |
| 11 | A vaccine candidate of attenuated genotype VII Newcastle disease virus generated by reverse genetics显示文摘 | Shunlin Hu Huailiang Ma Yantao Wu Wenbo Liu Xiaoquan Wang Yuliang Liu Xiufan Liu | 2008 | Vaccine2008，，6： | 1 |
| 12 | Topical transport of hydrophilic compounds using water-in-oil nanoemulsions显示文摘 | Huailiang WU Chandrasekharan Ramachandran Norman D Weiner | 2001 | Int J Pharm2001，220，： | 1 |
| 13 | Crowd Abnor- mal Behavior Detection Based on Machine Learning 显示文摘 | Zhang Dongping Peng Huailiang Yu Haibin | 2013 | Informa- tion Technology Journal2013，12，6： | 1 |
| 14 | Enhanced microwave absorption property of bowl-like Fe3O4 hollow spheres/reduced graphene oxide composites显示文摘 | Xu Huailiang Bi Hong Yang Rueybin | | 0，，： | 1 |
| 15 | Multiple intron gain and loss events occurred during the evolution of Cenp-A gene显示文摘Centromere protein A(CENP-A) is a histone H3 like protein,and it plays a very important role in chromosomal segregation during mitosis and meiosis.The analyses on the exon-intron organization of the Cenp-A gene in representative genomes revealed that multiple intron gain and loss events have occurred during the evolution of Cenp-A gene in opisthokonta(common ancestor of fungi and animals).Moreover,our results revealed that at least two positions were conserved in the intron gain and loss events during the evolution of the Cenp-A gene. | FAN XinYu YU Li XU HuaiLiang LI Ying | 2013 | Chinese Science Bulletin2013，58，17： | 1 |
| 16 | Decay properties of Er^3+ ions in Er^3+:YAG and Er^3+:YAlO3显示文摘 | XU Huailiang ZHOU Lige DAI Zhenwen | 2002 | Physica B2002，324，： | 1 |
| 17 | Multiple vortex body vortex numerical simulation显示文摘 | LIU Hanxiao LIU Zhong LI Huailiang etal | 2011 | Advanced Materials Research2011，32，14： | 1 |
| 18 | Robust and ultralow-energy-threshold ignition of a lean mixture by an ultrashort-pulsed laser in the filamentation regime显示文摘Laser ignition(LI)allows for precise manipulation of ignition tinning and location and is promising for green combustion of automobile and rocket engines and aero-turbines under lean-fuel conditions with improved emission efficiency;however,achieving completely effective and reliable ignition is still a challenge.Here,we report the realization of igniting a lean methane/air mixture with a 100%success rate by an ultrashort femtosecond laser,which has long been regarded as an unsuitable fuel ignition source.We demonstrate that the minimum ignition energy can decrease to the sub-mJ level depending on the laser filamentation formation,and reveal that the resultant early OH radical yield significantly increases as the laser energy reaches the ignition threshold,showing a clear boundary for misfire and fire cases.Potential mechanisms for robust ultrashort LI are the filamentation-induced heating effect followed by exothermal chemical reactions,in combination with the line ignition effect along the filament.Our results pave the way toward robust and efficient ignition of lean-fuel engines by ultrashort-pulsed lasers. | Hongwei Zang Helong Li Wei Zhang Yao Fu Shanming Chen Huailiang Xu Ruxin Li | 2021 | Light(Science & Applications)2021，10，3： | 1 |
| 19 | Significant enhancement of multiple resonant sidebands in a soliton fiber laser显示文摘Resonant sidebands in soliton fiber lasers have garnered substantial interest in recent years due to their crucial role in understanding soliton propagation and interaction dynamics.However,most previous studies and applications were restricted to focusing on only the first few low-order resonant sidebands because higher-order sidebands usually decay exponentially as their wavelengths shift far away from the soliton center and are negligibly weak.Here we report numerically and experimentally significant enhancement of multiple resonant sidebands in a soliton fiber laser mode-locked by a nonlinear polarization evolution mechanism.The birefringence and the gain profile of the laser cavity were shown to be critical for this phenomenon.Multiple intense resonant sidebands were generated whose maximum intensity was more than 30 d B higher than that of the soliton,which is the highest yet reported,to our knowledge.To accurately predict the wavelengths of all high-order resonant sidebands,an explicit formula was derived by taking the third-order dispersion effect into account.The temporal features of multiple orders of resonant sidebands were characterized,which all exhibit exponentially decaying leading edges.This study provides insight into understanding the properties of high-order resonant sidebands in a soliton laser and opens possibilities for constructing multi-wavelength laser sources. | TIANQI ZHANG FANCHAO MENG QI YAN CHUANZE ZHANG ZHIXU JIA WEIPING QIN GUANSHI QIN HUAILIANG XU | 2023 | Photonics Research2023，11，11： | 0 |
| 20 | Diet and feeding behavior of a group of high-altitude rhesus macaques: high adaptation to food shortages and seasonal fluctuations显示文摘Diet and feeding behavior data are crucial to a deep understanding of the behavioral response and adaptation of primates to a high-altitude environment.From August 2019 to June 2021,we collected data on the feeding behavior of a high-altitude rhesus macaque Macaca mulatta group from Yajiang County,Western Sichuan Plateau,which has an altitude of over 3,500 m.The results showed that feeding(33.0±1.8%)and moving(28.3±2.6%)were the dominant behavior of rhesus macaques.Macaques ate 193 food items,comprising 11 food categories from 90 species.Our study found that plant roots(30.9±30.1%)and young leaves(28.0±33.1%)were the main foods eaten by macaques.The preferred foods of rhesus macaques were young leaves,fruits,and seeds,and the consumption of these items was positively correlated with its food availability.When the availability of preferred foods was low,macaques took plant roots,barks,and fallen leaves as fallback foods.In particular,roots were a dominant food item in winter,and this way of feeding became a key survival strategy.Our results suggest that,facing the relative scarcity and strong seasonal fluctuations of food resources in high-altitude habitat,macaques adopt active foraging strategies,relying on a variety of food species and adjusting flexibly their food choices based on food availability,which may help to maximize the energy efficiency of high-altitude macaques. | Kechu Zhang Fazal Karim Zuxiang Jin Hongtao Xiao Yongfang Yao Qingyong Ni Bajin Li Wangjia Pu-Cuo Zhonghao Huang Huailiang Xu | 2023 | Current Zoology2023，69，3： | 0 |
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