|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | An ecological risk assessment for heavy metals of the lead-zinc ore tailings显示文摘The structure of Pb, Zn, Cu and Cd in lead zinc ore tailing soils in Yongzhou, Hunan is analyzed by the optimized BCR sequential extraction procedure. The content and proportion of heavy metals of the mine are measured. Meanwhile, the ecological risks are evaluated with the Lars Hakanson’s potential ecological risk exponential method. The analysis shows that the content of heavy metals is very high, reaching the level of serious pollution. The order of metal pollution degrees are Cd>Pb>Cu>Zn. On the other hand, it is very possible that the heavy metals may combine together as compounds or cling to the crystal form of clay. Since the form of soluble acid and free metals are very little, it is not an easy job for metal eluting or restoration of plants. Yet it is possible to take out those heavy metals adopting the chemical extraction technology. DTPA and EDTA, indicated by a research, both have iterative value and strong conformity effect. So they are effective elutriants to restore the polluted soil. A chemical extraction method is put forward in this paper. | Peng Huibing Liu Yunguo Li Jun Liu Meiying | 2007 | Ecological Economy2007，3，2： | 5 |
| 2 | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor显示文摘Dear Editor,Dopamine acts as an essential neurotransmitter whose signaling is conducted through five G protein-coupled receptors(GPCRs),dopamine D1 to D5 receptors(DRD1–DRD5).1 The D1-like receptors,comprising DRD1 and DRD5,primarily couple to the Gs family of G proteins to activate adenylyl cyclase and induce cAMP production.DRD1 is the most abundantly expressed dopamine receptor in the CNS.1 It is the central receptor mediating excitatory dopamine signaling in multiple dopaminergic pathways.Dysregulation of DRD1 signaling has been directly linked to Parkinson’s disease(PD),schizophrenia,and drug abuse. | Youwen Zhuang Brian Krumm Huibing Zhang X.Edward Zhou Yue Wang Xi-Ping Huang Yongfeng Liu Xi Cheng Yi Jiang Hualiang Jiang Cheng Zhang Wei Yi Bryan L.Roth Yan Zhang H.Eric Xu | 2021 | Cell Research2021，31，5： | 2 |
| 3 | Molybdenum Oxynitride Atomic Nanoclusters Bonded in Nanosheets of N-Doped Carbon Hierarchical Microspheres for Efficient Sodium Storage显示文摘Transition metal nitrides have attracted considerable attention as great potential anode materials due to their excellent metallic conductivity and high theoretical specific capacity.However,their cycling performance is impeded by their instability caused by the reaction mechanism.Herein,we report the engineering and synthesis of a novel hybrid architecture composed of MoO2.0N0.5 atomic nanoclusters bonded in nanosheets of N-doped carbon hierarchical hollow microspheres(MoO2.0N0.5/NC)as an anode material for sodium-ion batteries.The facile self-templating strategy for the synthesis of MoO2.0N0.5/NC involves chemical polymerization and subsequent one-step calcination treatments.The design is benefi-cial to improve the electrochemical kinetics,buffer the volume variation of electrodes during cycling,and provide more interfacial active sites for sodium uptake.Due to these unique structural and compositional merits,these MoO2.0N0.5/NC exhibits excellent sodium storage performance in terms of superior rate capability and stable long cycle life.The work shows a feasible and effective way to design novel host candidates and solve the long-term cycling stability issues for sodium-ion batteries. | Xiaona Pan Baojuan Xi Huibing Lu Zhengchunyu Zhang Xuguang An Jie Liu Jinkui Feng Shenglin Xiong | 2022 | Nano-Micro Letters2022，14，10： | 1 |
| 4 | Oxygen-Reconstituted Active Species of Single-Atom Cu Catalysts for Oxygen Reduction Reaction显示文摘Identification of an active center of catalysts under realistic working conditions of oxygen reduction reaction(ORR)still remains a great challenge and unclear.Herein,we synthesize the Cu single atom embedded on nitrogen-doped graphene-like matrix electrocatalyst(abbreviated as SA-Cu/NG).The results show that SA-Cu/NG possesses a higher ORR capability than 20%Pt/C at alkaline solution while the inferior activity to 20%Pt/C at acidic medium.Based on the experiment and simulation calculation,we identify the atomic structure of Cu-N_(2)C_(2) in SA-Cu/NG and for the first time unravels that the oxygenreconstituted Cu-N_(2)C_(2)-O structure is really the active species of alkaline ORR,while the oxygen reconstitution does not happen at acidic medium.The finding of oxygen-reconstituted active species of SA-Cu/NG at alkaline media successfully unveils the bottleneck puzzle of why the performance of ORR catalysts at alkaline solution is better than that at acidic media,which provides new physical insight into the development of new ORR catalysts. | Liu Yang Haoxiang Xu Huibing Liu Xiaofei Zeng Daojian Cheng Yan Huang Lirong Zheng Rui Cao Dapeng Cao | 2020 | Research2020，，1： | 0 |
| 5 | Luminescent properties of Ce^(3+),Er^(3+) co-doped La_3Si_6N_(11)显示文摘In order to obtain near-infrared phosphor pumped by blue chip with high luminous efficiency, a novel near-infrared phosphor Ce^(3+)/Er^(3+) doped La_3Si_6N_(11) was designed and firstly prepared via conventional solid-state reactions. The structure and morphology of Ce^(3+)/Er^(3+) doped La_3Si_6N_(11) were investigated by X-ray diffraction(XRD) and scanning electron microscopy(SEM). Compared with Er^(3+) doped La_3Si_6N_(11),the emission intensity of the Ce^(3+), Er^(3+) co-doped phosphor can be increased more than 5 times.Meanwhile, the mechanism of energy transfer from Ce^(3+) to Er^(3+) is confirmed according to the excitation,emission spectra and decay lifetimes curve. Above results suggest that La_3 Si_6 N_(11):Ce^(3+),Er^(3+) is a promising near-infrared phosphor for blue pumped LEDs(light-emitting diodes). | Yuan Xue Ronghui Liu Yuanhong Liu Huibing Xu Guantong Chen Xia Zhang Wei Gao Ze Jiang | 2019 | Journal of Rare Earths2019，37，3： | 0 |
| 6 | Thymidylate synthase confers pemetrexed resistance of non-small cell lung cancer cells by EGFR/PI3K/AKT pathway显示文摘Chemotherapy drug resistance is the main cause leading to the relapse and metastasis of non-small cell lung cancer(NSCLC)patients.Our study aimed to investigate the mechanism of pemetrexed resistance in NSCLC.Firstly,the pemetrexed(PEM)-resistant PC-9 and A549 lung adenocarcinoma cell lines(PC-9/PEM and A549/PEM)were established.The expression of thymidylate synthase(TS)in PC-9/PEM,A549/PEM,A549,and PC-9 cells were analyzed by qRT-PCR and western blot.Then,cell viability,colony formation,migration,and invasion were performed on PEM-resistant cells transfected with TS siRNA.The role of EGFR in PEM resistance of PEM-resistant cells was investigated using EGFR siRNA.The effects of gefitinib and EGFR siRNA on EGFR/PI3K/AKT pathway and downstream signaling Cyclin D1 and E2F1 in PEM-resistant cells were analyzed.Results showed that the protein level of TS was significantly increased in A549/PEM and PC-9/PEM.TS knockdown inhibited the potency of proliferation,colony-forming potential,migration,and invasion in PEM-resistant cells.EGFR knockdown abrogated the resistance to PEM of PEM-resistant cells and suppressed the migration and invasion of PEM-resistant cells.Gefitinib treatment and EGFR knockdown respectively inhibited the EGFR/PI3K/AKT pathway and downregulated Cyclin D1 and E2F1 in PEM-resistant cells.Thus,TS might be a predictive marker for PEM resistance in NSCLC.Inhibition of the EGFR pathway abrogated the resistance to PEM and inhibited the EGFR/PI3K/AKT and downstream signaling of PEM-resistant NSCLC cell lines. | DAN ZHANG HAIJING LIU ZHENNAN YI YUANYUAN LU YANYAN CHEN WEIQIANG SU HUIBING LIN ZHIHUI ZHANG WEI LEI | 2021 | BIOCELL2021，45，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员