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| 1 | Helicobacter pylori associated gastric intestinal metaplasia:Treatment and surveillance显示文摘Gastric cancer(GC) is one of the leading causes of cancer related death in the world, particularly in East Asia. According to the Correa's cancer cascade, noncardia GC is usually developed through a series of mucosal changes from non-atrophic gastritis to atrophic gastritis(AG), intestinal metaplasia(IM), dysplasia and adenocarcinoma. Atrophic gastritis and IM are therefore generally considered to be pre-neoplastic gastric lesions. Helicobacter pylori(H. pylori) infection is an important initiating and promoting step of this gastric carcinogenesis cascade. Emerging long-term data showed that eradication of H. pylori reduced the risk of subsequent cancer development. It however remains confusing whether eradication of the bacterium in individuals with pre-neoplastic gastric lesions could regress these changes as well as in preventing cancer. Whilst H. pylori eradication could likely regress AG, the presence of IM may be a point of no return in this cascade. Hence, surveillance by endoscopy may be indicated in those with extensive IM or those with incomplete IM, particularly in populations with high GC risk. The optimal interval and the best tool of surveillance endoscopy remains to be determined in future studies. | Kevin Sze-Hang Liu Irene Oi-Ling Wong Wai K Leung | 2016 | World Journal of Gastroenterology2016，22，3： | 23 |
| 2 | 睾丸主要血管或睾丸网旁取精点与取精成功率不具显著相关性:以220例非梗阻性无精子症患者行传统或显微睾丸取精术为例显示文摘采用传统与显微睾丸取精术相结合方式对220例梗阻性无精症患者行精子提取术,如果传统手术方式未见精子即为阴性取精位点,然后选取2—3个阴性取精位点行显微睾丸取精术。术中通过手术显微镜评价睾丸血管系统,同时记录阳性取精位点与睾丸血供的关系。总的精子获取率为58-2%,早期应用传统手术方式精子获取率为46.8%,而后行显微睾丸取精术则精子获取率增加11.7%。故显微睾丸取精术的应用可显著增加精子获取率(P=0.017),且在睾丸网或睾丸主要血管处并不能显著增加阳性取精位点。 | J Ullrich Schwarzer Heiko Steinfatt Heiko Steinfatt Manfred Schleyer Frank M Kōhn Klaus Fiedler2, Irene von Hertwig Gottfried Krüsmann Wolfgang Würfel | 2013 | Asian Journal of Andrology2013，15，6： | 5 |
| 3 | The American Academy of Neurology affirms the value of this guideline显示文摘 | Harbaugh S Claiborne J Irene K | 2006 | Circulation2006，113，5： | 1 |
| 4 | Hydrogel matrix entrapping PLGA-paclitaxel microspheres: drug delivery with near zero-order release and implantability advantages for malignant brain tumour chemotherapy 显示文摘 | Sudhir H R Irene K William B K | 2009 | Pharmaceutical Research2009，26，9： | 1 |
| 5 | The importance of shallow sediments in the recruitment of Anabaena and Aphanizomenon ( Cyanophyceae ) 显示文摘 | Irene K E Brunberg A K | 2004 | Journal of phycology2004，40，： | 1 |
| 6 | Maternal request: a reason for rising rates of cesarean section?显示文摘 | Andrea K Irene H Rahel T | 2012 | Arch Gynecol Obstet2012，286，： | 1 |
| 7 | A complete screening of the IL-4 gene: Novel polymorphisms and their association with asthma and IgE in childhood 显示文摘 | Michael K Iren T David C | 2003 | J Allergy Clin Immunol2003，112，5： | 1 |
| 8 | Late polymicrobial transjugular intrahepatic portosystemic shunt infection in a liver transplant patient:A case report显示文摘BACKGROUND Infection of a transjugular intrahepatic portosystemic shunt(TIPS)stent is a rare and serious complication that most commonly occurs during TIPS creation and revision.Patients typically present with recurrent bacteremia due to shunt occlusion or vegetation.To date there are approximately 58 cases reported.We present a patient diagnosed with late polymicrobial TIPS infection five years following TIPS creation.CASE SUMMARY A 63-year-old female status-post liver transplant with recurrent cirrhosis and portal hypertension presented with sepsis and recurrent extended-spectrum betalactamase Escherichia coli bacteremia.Computed tomography of the abdomen revealed an occluded TIPS with thrombus extension into the distal right portal vein,and focal thickening of the cecum and ascending colon.Colonoscopy revealed patchy ulcers in these areas with histopathology demonstrating ulcerated colonic mucosa with fibrinopurulent exudate.Shunt thrombectomy and revision revealed infected-appearing thrombus.Patient initially cleared her infection with antibacterial therapy and TIPS revision;however,soon after,she developed Enterobacter cloacae bacteremia and Candida glabrata and C.albicans fungemia with recurrent TIPS thrombosis.She remained on antifungal therapy indefinitely and later developed vancomycin-resistant Enterococcus faecium with recurrent TIPS thrombosis.The option of liver re-transplant for removal of the infected TIPS was not offered given her critical illness and complex shunt anatomy.The patient became intolerant to linezolid and elected hospice care.CONCLUSION Clinicians should be aware that TIPS superinfection may occur as long as five years following TIPS creation in an immunocompromised patient. | Irene De La Caridad Perez Ziv J Haskal John I Hogan Curtis K Argo | 2022 | World Journal of Hepatology2022，14，4： | 1 |
| 9 | Physico-chemical stability of docetaxel premix solution and docetaxel infusion solutions in PVC bags and polyolefine containers显示文摘 | Judith T Irene K | 1999 | Pharm World sci1999，21，3： | 1 |
| 10 | Absolute quantification of cer ebrai blood flow in neurologically normal volunteers:dynamic-susceptibility contrast mri-perfusion compared with computed tomography (CT)-perfusion显示文摘 | Doerthe Z Goran S Irene K | 2009 | Magn Resonan Med2009，62，1： | 1 |
| 11 | Urban environmental quality and human well--being towards a conceptual framework and demarcation of concepts: a literature study 显示文摘 | Irene K Kees L Gooitske M | 2003 | Landscape and Urban Planning2003，65，： | 1 |
| 12 | Metabolic modeling of fumaric acid production by Rhizopus arrhizus 显示文摘 | Irene C G William A W Frenerick A K | 1991 | Applied Biochemistry and Biotechnoiogy1991，28，29： | 1 |
| 13 | The importance of shallow sediments in the recruitment of Anabaena and Aphanizomenon (Cyanophyceae) 显示文摘 | Irene K E Brunberg A K | 2004 | J Phycol2004，40，： | 1 |
| 14 | Robust visual object tracking using multi-mode anisotropie Mean Shift and particle filters显示文摘 | HASAN Z IRENE K GU Yu-hua etal | 2011 | IEEE Transactions on Circuits and Systems for Video Technology2011，21，1： | 1 |
| 15 | A complete screening of IL-4 gene:Novel polymorphisms and their association with asthma and IgE in childhood显示文摘 | Michael K Iren T David C | 2003 | Allergy Clin Immunol2003，12，： | 1 |
| 16 | The role of alteredi regulation in apoptosis,oncosis and necrosis显示文摘 | Benjarmin F T Irene K B | 1996 | Biochem Biophy Acta1996，1313，： | 1 |
| 17 | Design and function of novel superplasticizers for more durable high performance concrete (superplast project)显示文摘 | Yves F. Houst Paul Bowen Fran?ois Perche Annika Kauppi Pascal Borget Laurent Galmiche Jean-Fran?ois Le Meins Fran?oise Lafuma Robert J. Flatt Irene Schober Phil F.G. Banfill David S. Swift Bernt O. Myrvold Berit G. Petersen K?re Reknes | 2008 | Cement and Concrete Research2008，，10： | 1 |
| 18 | Adaptive background subtraction based on feedback from fuzzy classification 显示文摘 | Li Li-yuan Gu Irene Yu-Hua Leung Maylor K H | 2004 | Optical Engineering2004，43，10： | 1 |
| 19 | The importance of shallow sediments in the recruitment of Anabaena and Aphanizomenon (Cyanophyceae) 显示文摘 | Irene K E Brunberg A K | 2004 | Journal of Phycology2004，40，5： | 1 |
| 20 | High pressure processing of Australian navel orange juices:Sensory analysis and volatile flavor profiling显示文摘 | Irene A B Kerry E Sehneebeli K | 2005 | Innovative Food Science and Emerging Technologies2005，，6： | 1 |
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