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| 1 | Effect of mucin production on survival in colorectal cancer:A case-control study显示文摘AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage.METHODS: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (< 50% mucin). Group D consisted of all patients with tumors having < 75% mucin (controls and groups A together).RESULTS: Median survival in MCRC and NMCRC groups was 46.2 and 112.9 mo, respectively (P = 0.26). OS in groups A and B was 70.1 and 32.8 mo (P = 0.46), and in groups B and D was 32.8 and 70.1 mo, respectively (P = 0.143). TTP in MCRC and NMCRC was 50.17 and 44.77 mo, respectively (P = 0.795). TTP in groups A, B, and D was 70.1, 24.8, and 65.5 mo, respectively. Twenty-eight percent of patients with MCRC had poorly differentiated adenocarcinoma versus 8.6% in NMCRC patients (P = 0.028).CONCLUSION: MCRC is associated with a non-significant decrease in median survival and TTP, particularlywhen mucin content is > 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed. | Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine | 2008 | World Journal of Gastroenterology2008，14，45： | 6 |
| 2 | Chemical and sensory evalution of aromatic rice cuhivars显示文摘 | Itani T Takada A Tamaki M | 1994 | Crop Science1994，34，： | 1 |
| 3 | Damage avoidance design of special truss moment frames with energy dissipating devices显示文摘 | Pekcan G Linke C Itani A | 2009 | Journal of Constructional Steel Research2009，65，6： | 1 |
| 4 | Tumor necrosis factor-alpha regulates inducible nitric oxide synthase gene expression in the portal hypertensive gastric mucosa of the rat显示文摘 | Ohta M Itani R | 1997 | J Gastrointest Surg1997，1，： | 1 |
| 5 | Treating foot infections in diabetic patients: a randomized, muhicenter, open-label trial of linezolid versus ampicillin-sulbactam/amoxicillin-clavulanate显示文摘 | Lipsky B A Itani K Norden C | 2010 | Clinical Infectious Diseases2010，19，11： | 1 |
| 6 | Damage avoidance design of special truss moment frames with energy dissipating devices显示文摘 | Pekcan G Linke C Itani A | 2009 | Joumal of Constructional Steel Research2009，65，6： | 1 |
| 7 | Live-load Moments forContinuous Skew Bridges显示文摘 | KHALEEL M A ITANI R Y | 1990 | Journal of StructuralEngineering1990，116，9： | 1 |
| 8 | Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl CoA carboxylase inhibition and AMP activated protein kinase activation显示文摘 | Tomas E Tsao T S Saha A K Murrey H E Zhang C C Itani S I | 2002 | Proc Natl Acad Sci USA2002，99，16： | 1 |
| 9 | ln- terleukinsl beta and 6 but not transforming growth factor -beta are essentialtbr the differentiation of interleukin 17 - producing human T helpex:e/ls 显示文摘 | Acosta - Rodriguez EV Napo|itani G Lanzavecchia A | 2007 | Nat lmmuno12007，8，9： | 1 |
| 10 | Live-load moments for continuous skew bridge显示文摘 | Kahleel Mohammad A Itani Rafik Y | 1990 | Structure Engineering1990，16，9： | 1 |
| 11 | Tumor necrosis factor-alpha regulates inducible nitric oxide synthase gene expression in the portal hypertensive gastric mucosa of the rat 显示文摘 | Kaviani A Ohta M Itani R | 1997 | J Gastrointest Surg1997，1，4： | 1 |
| 12 | Squamous cell carcinoma of the pancreas显示文摘 | Itani KMF Karni A Green L | | 0，，： | 1 |
| 13 | Cyclic behavior of shear links of various grades of plate steel显示文摘 | DUSICKA P ITANI A BUCKLE I | 2010 | Journal of Structural Engineering2010，136，4： | 1 |
| 14 | Association of onset of obesity with sleep duration and shift work among Japanese adults 显示文摘 | Itani O Kaneita Y Murata A | 2011 | Sleep Med2011，12，4： | 1 |
| 15 | An automated multiscale ensemble simulation approach for vascular blood flow 显示文摘 | ITANI M A Schiller U D Schmieschekb S | 2015 | Journal of Computational Sci- ence2015，，9： | 1 |
| 16 | Cyclic response of plate steels under large inelastic strains 显示文摘 | Dusicka P Itani A M Buckle I G | 2007 | Journal of Constructional Steel Research2007，63，2： | 1 |
| 17 | Ultrasound evaluation of the anatomical characteristics of the internal jugular vein and carotid artery-facilitation of internal jugular vein cannulation显示文摘 | Sibai A N Loutfi E Itani M | 2008 | Middle East J Anesthesiol2008，19，6： | 1 |
| 18 | Acute regula- tion of tight junction ion selectivity in human airway epithe- lia显示文摘 | Flynn A N Itani O A Moninger T O | 2009 | Proc Nail Acad Sei USA2009，106，9： | 1 |
| 19 | Seismic behavior of open-web truss-moment frames显示文摘 | GOEL S C ITANI A M | 1994 | Journal of Structural Engineering1994，120，6： | 1 |
| 20 | Discovery of FR166124,a novel water-soluble pyrazolo-pyridine adenosine A1receptor antagonist显示文摘 | Kuroda S Akahane A Itani H | 1999 | Bioorg Med Chem Lett1999，9，14： | 1 |
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