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| 1 | Calcium dobesilate for diabetic retinopathy: a systematic review and meta-analysis显示文摘Many randomized clinical controlled trials have confirmed the efficacy and safety of calcium dobesilate in treating diabetic retinopathy(DR).This systematic review critically evaluated the evidence that links calcium dobesilate to DR.In this fixed-effects meta-analysis,a total of 221 pertinent English-language articles published between January 1975 and October 2013 were identified.Systematic searches of PUBMED,Springer Link and the Cochrane Clinical Trials Database were conducted using the keywords 'diabetic retinopathy' and 'calcium dobesilate'.The extracted information included the study design,inclusion and exclusion criteria,setting,sample size,participant mean age,treatment regime,mean change in best corrected visual acuity,laboratory parameters,capillary fragility,intraocular pressure and fundus manifestations based on the findings of fluorescent angiography.The summary statistics indicated that calcium dobesilate was significantly associated with improving retinal microaneurysms(RR: 0.62,95%CI: 0.42?0.90,P=0.01),retinalhemorrhages(RR: 0.39,95% CI: 0.17?0.88,P=0.02); exudates(RR: 0.31,95% CI: 0.12?0.81,P=0.02),reduction of whole blood viscosity(MD: ?0.57 CP,95% CI: ?0.75 to ?0.38,P<0.001),plasma viscosity(MD: ?0.36 CP,95% CI: ?0.63 to ?0.09,P=0.01) and blood cholesterol(MD: ?0.48 mg m L?1,95% CI: ?0.64?0.33,P<0.00001).Intraocular pressure was also significantly reduced(MD: ?5.59 mm Hg,95% CI: ?6.69 to ?4.50,P<0.00001).The results indicate that calcium dobesilate effectively treats DR at the systematic and local ocular levels. | ZHANG XinYuan LIU Wei WU ShanShan JIN JingLong LI WeiHong Wang NingLi | 2015 | Science China(Life Sciences)2015，58，1： | 54 |
| 2 | Photochemical pollution in Lanzhou, China - A case study显示文摘The photochemical air pollution in Xigu district of Lanshou city, Gansu Province was studied during a period of 1981-1984. The extremely high NMHC/NOx ratio and ozone level elevation after rain have been noticed. A series of outdoor and indoor reaction chamber simulation experiments conducted in order to understand the specific conditions. The ozone formation under NMHC/NOx condition and the possible reason for high ozone concentration after rain are discussed. | Tang Xiaoyan , Li Jinglong, Dong ZhenXing, Wang Yuying,Wang Wenxing , Qi Liwen, Liu Xiling, Zhang Yutian, Zhang Xuejin,Tian Bingshen, Jin Suwen , Yang Lingqing and Zhang Yixin Department of Technical Physics,Peking University, Beijing, China. Chinese Reaearch Academy of Eavironmental Sciences, Beijing,China. Gansu Provincial Environmental Research Institute, Lanshou, China. Lanshou Petrochemical Engineering Institute, Lanshou, China. | 1989 | Journal of Environmental Sciences1989，1，1： | 15 |
| 3 | Comprehensive eco-environmental effects of the shelter-forest ecological engineering along the Tarim Desert Highway显示文摘In this work, we report a comprehensive study about the eco-environmental effects of the shelter forest along the Tarim Desert Highway, including the effects on aeolian environment, soil, micro-climate, biodiversity, and groundwater. The results show that: (1) The movement of windblown sand near the ground surface was affected by the shelter forest. The wind speed and sediment transport rate in the shelter forest decreased by 64%―80% and 87.45%―99.02%, respectively. In addition, there were also significant changes in the sand flux structure, the sand grain size, and the deflation and deposition on the ground surface. (2) Compared to the natural mobile sand, the soil bulk density in the forest area decreased while the total salt content, the total porosity, and the water content increased. In addition, the soil fertility was significantly improved in the forest area, and showed the 'first rapid, then slow' variation pattern. (3) The shelter forest showed positive effects on the micro-climate. Within the 6 m height above the ground, the air temperature in the shelter forest at different heights was lower than that in the mobile sand, while the air humidity was higher, while, the soil temperature was also lower in the shelter forest than mobile sand. (4) The number of soil microbial species increased significantly with the improvement of habitat in the shelterbelt. However, the population of different species was not distributed evenly across the surveyed area. (5) Currently, no significant effects of groundwater-pumping and forest-irrigation water have been found on the groundwater level and its salinity. The variation amplitude of both groundwater level and salinity was at the level of centimeters and 1g/L, respectively. No obvious variation trend has been observed. | LEI JiaQiang LI ShengYu JIN ZhengZhong FAN JingLong WANG HaiFeng FAN DongDong ZHOU HongWei GU Feng QIU YongZhi XU Bo | 2008 | Chinese Science Bulletin2008，53，S2： | 14 |
| 4 | New quantum matters:Build up versus high pressure tuning显示文摘In this article we briefly review new quantum functional compounds primarily based on our recent works.We will highlight the effects of pressures on both materials synthesis and quantum tuning.The contents include(I)'111'-type iron based superconducting system,(II)pressure induced superconductivity in topological insulators and(III)the new diluted magnetic semiconductors with decoupled spin charge doping. | JIN ChangQing WANG XianCheng LIU QingQing ZHANG SiJia FENG ShaoMin DENG Zheng YU RiCheng ZHU JingLong | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，12： | 11 |
| 5 | Microstructure and mechanical properties in the TLP joint of FeCoNiTiAl and Inconel 718 alloys using BNi2 filler显示文摘High entropy alloy(HEA) of Fe Co Ni Ti Al and Inconel 718 superalloy were firstly transient liquid phase(TLP) bonded by BNi2 filler due to the diffusion of Si and B in the filler to the base metals. The effects of bonding time on microstructure evolution and mechanical properties of the TLP joints were investigated.Owing to the complete isothermal solidification of the joints bonded for 30 min 120 min at 1100°C,no athermally solidified zones(ASZs) formed by eutectic phases were observed in the welded zone. Thus the TLP joints were only composed by the isothermally solidified zone(ISZ) and two diffusion affected zone(DAZ) adjacent to the dissimilar base metals and the negative effect of the ASZ on joint properties can be avoided. In addition, the increase of the bonding time can also make the Ti B2 borides precipitated in the DAZ near HEA and the brittle borides or carbides in the DAZ near IN718 alloy decrease and reduce the possibility of the stress concentration happened in the joints under loading. Therefore, the highest shear strength(632.1 MPa) of the TLP joints was obtained at 1100°C for 120 min, which was higher than that of the joint bonded for 30 min, 404.2 MPa. Furthermore, the extension of the bonding time made the fracture mechanism of the joint be transformed from the intergranular fracture to the transgranular fracture. However, as the brittle borides in the DAZ near IN718 can not be eliminated completely and refining of grains also happened in such region, all the TLP joints fractured inner the DAZ near IN718 alloy. | Lin Yuan Jiangtao Xiong Yajie Du Jin Ren Junmiao Shi Jinglong Li | 2021 | Journal of Materials Science & Technology2021，，2： | 3 |
| 6 | Characteristics of the soil microbial population in forest land irrigated with saline water in the desert area显示文摘The study of soil microbial populations and diversity is an important way to understanding the soil energy process.In this study we analyzed the characteristics of soil microbial populations of the Tarim Desert Highway shelter-forest,by identifying microbial fatty acids and using methods of conventional cul-tivation.The results illustrated that the amount of soil microbial activity and the diversity of soil microbial fatty acid increased significantly with the plantation age of the shelter-forest;the soil microbial population was dominated by bacteria.The fatty acids of C14︰0,C15︰0,C16︰0,C17︰0,C18︰1ω9,C18︰0,C18︰2ω6 and C21︰0 were found to be dominant soil microbial fatty acids in the shelter-forest soil.Prin-cipal analysis and regression analysis showed that(1) concentrations of fatty acids of C14︰0,C16︰0 and C18︰0 could be used as indicators of total soil microbial population;(2) soil bacteria and actinomycetes populations were closely correlated with the amount of fatty acids of C15︰0 and C17︰0;and(3) soil fungi were closely correlated with the amount of fatty acids of C18︰1ω9 and C18︰2ω6. | Jin, ZhengZhong Lei, JiaQiang Xu, XinWen Li, ShengYu Fan, JingLong Zhao, SiFeng | 2010 | Journal of Arid Land2010，2，2： | 2 |
| 7 | Schisandrin B exerts anticancer effects on human gastric cancer cells through ROS-mediated MAPK,STAT3,and NF-κB pathways显示文摘Schisandrin B(Sch B)is a monomer with anti-cancer and anti-inflammatory effects,which are isolated from the plant Schisandra chinensis(Turcz)Baillon.We investigated the anti-gastric cancer(GC)effects of Sch B and its underlying molecular mechanisms.The Cell Counting Kit-8 assay was used to determine the effects of Sch B on the viability of GC and normal cell lines.Hoechst/propidium iodide staining and flow cytometry were used to assess the apoptosis induction of Sch B.Western blotting was used to evaluate the effects of Sch B on downstream apoptotic proteins.The DCFH-DA fluorescent probe was used to assess the regulatory effects of Sch B on reactive oxygen species(ROS)levels and related signaling pathways in GC cells.The results showed that Sch B could regulate the phosphorylation level of mitogen-activated protein kinase(MAPK)by upregulating ROS accumulation in gastric cancer cells,and then reduce the expression of nuclear factor kappa B(NF-κB)and phosphorylated transcription 3(p-STAT3).In addition,Sch B downregulated the cell cycle proteins cyclin-dependent kinase 2/4/6 and cyclin D1/E,and arrested cells in the G0/G1 phase.Moreover,it also inhibited cell migration,which was reversed with Nacetylcysteine pretreatment.In summary,Sch B has killing effects on GC cells by upregulating the production of intracellular ROS and regulating the MAPK/STAT3/NF-κB signaling pathway,leading to the migration arrest and apoptosis of GC cells. | TIANZHU LI YU ZHANG TONG ZHANG YANNAN LI HUI XUE JINGLONG CAO WENSHUANG HOU YINGHUA LUO CHENGHAO JIN | 2023 | BIOCELL2023，47，1： | 0 |
| 8 | Biological Activity and Molecular Mechanism of Bullatine G显示文摘Bullatine G has many biological effects such as anti-inflammatory,anti-anxiety,anti-tumor,anti-arrhythmia and anti-heart failure effect.In order to provide a theoretical basis for the further study and clinical application of bullatine G,this article reviews the biological activity of bullatine G in recent years. | Jian LIU Jinglong CAO Hui XUE Yannan LI Wenshuang HOU Chenghao JIN | 2023 | Medicinal Plant2023，14，2： | 0 |
| 9 | Pharmacological Effects and Molecular Mechanism of Osthole显示文摘Osthole has various pharmacological effects such as anti-cancer,anti-inflammation,prevention and treatment of cardiovascular diseases and neuroprotection.This paper reviews the advances in the research of the pharmacological effects and molecular mechanisms of osthole,in order to provide new ideas for further research and clinical application of osthole. | Yannan LI Wenshuang HOU Jinglong CAO Anqi WANG Yinghua LUO Chenghao JIN | 2023 | Medicinal Plant2023，14，2： | 0 |
| 10 | Pharmacological Activities and Molecular Mechanisms of Arctigenin显示文摘Arctigenin has a variety of pharmacological effects,such as anti-inflammatory,anti-tumor,antiviral and hypoglycemic.In this paper,the pharmacological effects and mechanisms of arctigenin were reviewed,in order to provide a theoretical basis for further research and development of arctigenin. | Wenshuang HOU Jinglong CAO Jian LIU Hui XUE Yannan LI Chenghao JIN | 2023 | Medicinal Plant2023，14，2： | 0 |
| 11 | Optimization of Extraction, Purification and Identification Process of Bullatine G显示文摘The purification processes of bullatine G, such as acid water extraction, ammonia alkalization ether cold soaking method, ultrasonic assisted extraction and cellulase extraction, and the determination technologies of bullatine G content, such as UV-spectrophotometry, chromatography, near infrared spectroscopy (NLR), thin layer chromatography (TLC), high performance liquid chromatography-mass spectrometry (HPLC-MS) were reviewed, in order to provide a theoretical basis for the development and application of bullatine G. | Jian LIU Jinglong CAO Hui XUE Yannan LI Wenshuang HOU Yinghua LUO Chenghao JIN | 2022 | Plant Diseases and Pests2022，13，6： | 0 |
| 12 | Research Progress on Purification Process Optimization and Content Determination of Zeaxanthin显示文摘At present,the purification process of zeaxanthin mainly includes organic solvent extraction,ultrasonic-assisted extraction and enzyme extraction,and the content determination technology mainly includes ultraviolet-spectrophotometry and high performance liquid chromatography.In this paper,the purification process and content determination technology of zeaxanthin in recent years are reviewed in order to provide ideas and theoretical basis for further research and application of zeaxanthin. | Jian LIU Jinglong CAO Hui XUE Yannan LI Wenshuang HOU Chenghao JIN | 2023 | Asian Agricultural Research2023，15，3： | 0 |
| 13 | Heterogeneous Deformation Behaviors of an Inertia Friction Welded Ti_(2)AlNb Joint:an In‑situ Study显示文摘A defect-free Ti_(2)AlNb joint has been obtained by the inertia friction welding(IFW)technology.The weld zone(WZ)is composed of B2 grains refined by discontinuous dynamic recrystallization and enhanced by grain refinement strengthening.And the average microhardness decreases by about 30 HV from the WZ to the base metal.In-situ SEM analysis reveals that the heterogeneous structure of the joint causes strong strain partitioning during tensile deformation.The microcrack initiation occurs at the interface of the initial B2 phases and B2/O boundaries.Owing to stress concentration,the multi-slip bands and cracks tend to generate in the heat-affected zone(HAZ),causing a premature fracture. | Dingcong Cui Qingfeng Wu Feng Jin Chenbo Xu Mingxin Wang Zhijun Wang Junjie Li Feng He Jinglong Li Jincheng Wang | 2023 | Acta Metallurgica Sinica(English Letters)2023，36，4： | 0 |
| 14 | Microstructure and mechanical properties of transient liquid phase bonding DD5 single-crystal superalloy to CrCoNi-based medium-entropy alloy显示文摘This study focuses on the transient liquid phase(TLP)bonding of DD5 single-crystal superalloy to Cr Co Nibased medium-entropy alloy(MEA)using a BNi-2 filler alloy.The microstructure and mechanical properties of the TLP-bonded DD5/MEA joint were evaluated,and the microstructural evolution mechanism was investigated.The formation of the isothermal solidification zone(ISZ)depended on the diffusion of the melting-point depressants(Si and B elements)from the liquid filler into the DD5 and MEA substrates,as well as the dissolution of the substrates.Boron diffused along theγchannel of DD5 and reacted to form M_(5)B_(3)boride,herein referred to as the diffusion-affected zone(DAZ I).Similarly,the Cr_(5)B_(3)boride precipitated in the Ni-rich MEA matrix adjacent to the MEA substrate(i.e.,DAZ II).Additionally,a coherent orientation of[0]_(BCY)//[011]_(FCC)and(002)_(BCY)//(200)_(FCC)was detected between M_(5)B_(3)boride with a body-centered tetragonal(BCT)structure and the face-centered cubic(FCC)matrix.The performance of the joint was dominated by the properties of the bonding seam.As the bonding time increased from 20to 80 min,the athermal solidification zone(including eutectic microstructure)was gradually replaced by the ISZ exhibiting excellent plastic deformation capability,and the shear strength of the joint was improved.The maximum shear strength(752 MPa)was achieved when the eutectic-free joint was bonded at 1050℃ for 80 min.The fracture morphology revealed a mixture mode,indicating the initiation of cracks in the DAZ II,mainly propagating in the ISZ,and passing through the DAZ I. | Shiwei Li Jinglong Li Junmiao Shi Yu Peng Xuan Peng Xianjun Sun Feng Jin Jiangtao Xiong Fusheng Zhang | 2022 | Journal of Materials Science & Technology2022，，1： | 0 |
| 15 | Review on marine collagen peptides induce cancer cell apoptosis,necrosis,and autophagy by reducing oxidized free radicals显示文摘Marine collagen peptides(MCPs)are natural products prepared by hydrolyzing marine collagen protein through a variety of chemical methods or enzymes.MCPs have a range of structures and biological activities and are widely present in marine species.MCPs also have a small molecular weight,are easily modified,and absorbed by the body.These properties have attracted great interest from researchers studying antioxidant,anti-tumor,and anti-aging activities.MCPs of specific molecular weights have significant anti-tumor activity and no toxic side effects.Thus,MCPs have the potential use as anti-cancer adjuvant drugs.Free radicals produced by oxidation are closely related to human aging,cancer,arteriosclerosis,and other diseases,but their relationship with cancer is not well known.In this review,we focus on the antioxidant properties of MCPs in the treatment of cancer,highlighting their antioxidant molecular structure and potential for clinical practice. | YINGHUA LUO YU ZHANG TONG ZHANG YANNAN LI HUI XUE JINGLONG CAO WENSHUANG HOU JIAN LIU YUHE CUI TING XU CHENGHAO JIN | 2023 | BIOCELL2023，47，5： | 0 |
| 16 | Purification Process and Biological Activity of Daphnoretin显示文摘Daphnoretin,belonging to coumarin compounds,is the main active ingredient of Wikstroemia indica,and has anti-inflammatory,anti-depression,anti-tumor and other pharmacological activities.This article reviews the extraction and purification process,content determination methods and pharmacological activity of daphnoretin,in order to provide a theoretical reference for optimization of purification process,improvement of content determination technique and further clinical application of daphnoretin. | Jinglong CAO Jian LIU Yannan LI Hui XUE Yinghua LUO Chenghao JIN | 2023 | Plant Diseases and Pests2023，14，1： | 0 |
| 17 | Preparation Process,Pharmacological Activity and Molecular Mechanism of Valepotriate显示文摘In recent years,with the continuous development of the medicinal value of valepotriate and the great attention of scholars.The traditional extraction and purification process can no longer meet the current market standards and needs.The modern technology of valepotriate is of great significance to its application and development.This paper reviews the extraction and purification process,molding process and pharmacological activity of valepotriate,providing a theoretical basis for the research and application of valepotriate. | Jinglong CAO Jian LIU Yannan LI Hui XUE Wenshuang HOU Ting XU Yuhe CUI Chenghao JIN | 2023 | Medicinal Plant2023，14，1： | 0 |
| 18 | Anti-inflammatory,Bacteriostatic and Anticancer Effects of Madecassoside显示文摘Madecassoside is a natural active component extracted from Centella asiatica.In recent years,a large number of studies have reported that madecassoside has a variety of biological activities,such as anticancer,anti-inflammatory and antibacterial effects,prevention and treatment of cardiovascular diseases,nerve damage,visceral damage and arthritis,and other pharmacological effects.In this paper,the pharmacological action and mechanism of madecassoside were reviewed to provide a theoretical basis for further research of madecassoside and drug development. | Wenshuang HOU Jinglong CAO Jian LIU Hui XUE Yannan LI Chenghao JIN | 2023 | Asian Agricultural Research2023，15，4： | 0 |
| 19 | Pharmacological Action and Molecular Mechanism of Amentoflavone显示文摘Amentoflavone(AMF)is a natural active substance extracted from Chinese herbal medicine Selaginella tamariscina,and has good anti-inflammatory,antitumor,hypoglycemic and neuroprotective pharmacological effects.This paper reviews the pharmacological action and mechanism of AMF,in order to lay a theoretical foundation for in-depth research and drug development of AMF. | Wenshuang HOU Jinglong CAO Jian LIU Hui XUE Yannan LI Chenghao JIN | 2023 | Plant Diseases and Pests2023，14，2： | 0 |
| 20 | Purification Process,Content Determination,Pharmacological Activity and Molecular Mechanism of Neogambogic Acid显示文摘Neogambogic acid is characterized by broad antitumor spectrum,good antitumor effect and low toxicity and side effects.This paper reviews the purification process,content determination and pharmacologic activity of neogambogic acid,in order to provide a theoretical reference for the research and application of neogambogic acid. | Tong ZHANG Jinglong CAO Wenshuang HOU Anqi WANG Yinghua LUO Chenghao JIN | 2023 | Plant Diseases and Pests2023，14，2： | 0 |
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