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| 1 | AttrLeaks on the Edge:Exploiting Information Leakage from Privacy-Preserving Co-inference显示文摘Collaborative inference(co-inference) accelerates deep neural network inference via extracting representations at the device and making predictions at the edge server,which however might disclose the sensitive information about private attributes of users(e.g.,race).Although many privacy-preserving mechanisms on co-inference have been proposed to eliminate privacy concerns,privacy leakage of sensitive attributes might still happen during inference.In this paper,we explore privacy leakage against the privacy-preserving co-inference by decoding the uploaded representations into a vulnerable form.We propose a novel attack framework named AttrL eaks,which consists of the shadow model of feature extractor(FE),the susceptibility reconstruction decoder,and the private attribute classifier.Based on our observation that values in inner layers of FE(internal representation) are more sensitive to attack,the shadow model is proposed to simulate the FE of the victim in the blackbox scenario and generates the internal representations.Then,the susceptibility reconstruction decoder is designed to transform the uploaded representations of the victim into the vulnerable form,which enables the malicious classifier to easily predict the private attributes.Extensive experimental results demonstrate that AttrLeaks outperforms the state of the art in terms of attack success rate. | WANG Zhibo LIU Kaixin HU Jiahui REN Ju GUO Hengchang YUAN Wei | 2023 | Chinese Journal of Electronics2023，32，1： | 0 |
| 2 | Avian influenza viruses suppress innate immunity by inducingtrans-transcriptional readthrough via SSU72显示文摘Innate immunity plays critical antiviral roles. The highly virulent avian influenza viruses (AIVs) H5N1, H7N9, and H5N6 can betterescape host innate immune responses than the less virulent seasonal H1N1 virus. Here, we report a mechanism by whichtranscriptional readthrough (TRT)-mediated suppression of innate immunity occurs post AIV infection. By using cell lines, mouselungs, and patient PBMCs, we showed that genes on the complementary strand (“trans” genes) influenced by TRT were involved inthe disruption of host antiviral responses during AIV infection. The trans-TRT enhanced viral lethality, and TRT abolishmentincreased cell viability and STAT1/2 expression. The viral NS1 protein directly bound to SSU72, and degradation of SSU72 inducedTRT. SSU72 overexpression reduced TRT and alleviated mouse lung injury. Our results suggest that AIVs infection induce TRT byreducing SSU72 expression, thereby impairing host immune responses, a molecular mechanism acting through the NS1-SSU72-trans-TRT-STAT1/2 axis. Thus, restoration of SSU72 expression might be a potential strategy for preventing AIV pandemics. | Yan Zhao Fengming Huang Zhen Zou Yuhai Bi Yang Yang Cong Zhang Qiang Liu Daozhen Shang Yiwu Yan Xiangwu Ju Song Mei Peng Xie Xiao Li Mingyao Tian Shuguang Tan Huijun Lu Zongsheng Han Kangtai Liu Yuqing Zhang Junbo Liang Zhu Liang Qingchao Zhang Jiahui Chang William JLiu Cong Feng Tanshi Li Michael Q.Zhang Xiaoyue Wang George FGao Yingxia Liu Ningyi Jin Chengyu Jiang | 2022 | Cellular & Molecular Immunology2022，19，6： | 0 |
| 3 | Fluorescent Aptamer-Polyethylene Glycol Functionalized Graphene Oxide Biosensor for Profenofos Detection in Food显示文摘A biosensor based on self-assembled ssDNA(aptamer)and polyethylene glycol functionalized graphene oxide(GO-PEG)has been designed for sensing profenofos in food.The sensor has employed the fluorescence'on/off'switching strategy in a single step iii homogeneous solution.Compared to traditional detection methods,the strategy proposed here is simple,convenient,fast and sensitive.Furthermore,compared with the general aptamer-GO structure,this aptamer-GO-PEG stmcture is in possession of a better detection performance,wliich is largely attributed to the improvement of the biocompatibility and the adjustment of the adsorption capacity of GO by grafting the blocking agent PEG onto the surface of GO.Additionally,the improved biocompatibility of GO shows better stability in salt solutions and physiological solutions,which is more conducive to its practical application in foods.In this project,profenofos had been detected with the proposed strategy,and the limit of detection has been controlled to be 0.21 ng/mL.This aptasensing assay has been applied to detemiining profenofos in(spiked)tap water,cabbage and milk with the recovery values ranging from 93.1% to 108.5%,from 90.8% to 113.2% and from 105.9% to 114.2%,respectively. | XIONG Jin'en LI Shuang LI Yi CHEN Yingli LIU Yu GAN Junlan JU Jiahui XIAN Yaoling XIONG Xiaohui | 2020 | Chemical Research in Chinese Universities2020，36，5： | 0 |
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