|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Residual renal function in peritoneal dialysis with failed allograft and minimum immunosuppression显示文摘Immunosuppression(IS) is often withdrawn in patients with end stage renal disease secondary to a failed renal allograft, and this can lead to an accelerated loss of residual renal function(RRF). As maintenance of RRF appears to provide a survival benefit to peritoneal dialysis(PD) patients, it is not clear whether this benefit of maintaining RRF in failed allograft patients returning to PD outweigh the risks of maintaining IS. A 49 year-old Caucasian male developed progressive allograft failure nine years after living-donor renal transplantation. Hemodialysis was initiated via tunneled dialysis catheter(TDC) and IS was gradually withdrawn. Two weeksafter IS withdrawal he developed a febrile illness, which necessitate removal of the TDC and conversion to PD. He was maintained on small dose of tacrolimus(1 mg/d) and prednisone(5 mg/d). Currently(1 year later) he is doing exceedingly well on cycler-assisted PD. Residual urine output ranges between 600-1200 m L/d. Total weekly Kt/V achieved 1.82. RRF remained well preserved in this patient with failed renal allograft with minimal immunosuppressive therapy. This strategy will need further study in well-defined cohorts of PD patients with failed allografts and residual RRF to determine efficacy and safety. | Nadear Elmahi éva Csongrádi Kenneth Kokko Jack R Lewin Jamie Davison Tibor Fülp | 2013 | World Journal of Transplantation2013，3，2： | 5 |
| 2 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 3 | Increasing diabetes self-management education in community settings显示文摘 | Susan L Norris Phyllis J Nichols Carl J Caspersen Russell E Glasgow Michael M Engelgau Leonard Jack Susan R Snyder Vilma G Carande-Kulis George Isham Sanford Garfield Peter Briss David McCulloch | 2002 | American Journal of Preventive Medicine2002，，4： | 2 |
| 4 | An object-oriented random number package with many long streams and substreams显示文摘 | L’ECUYER P Simard R Jack C | 2002 | Operations Research2002，，2： | 1 |
| 5 | Biological souring and mitigation in oil reservoirs 显示文摘 | Gieg L M Jack T R Foght J M | 2011 | Applied Microbiology and Biotechnology2011，92，2： | 1 |
| 6 | Tectonostratigraphic development of the Interior Sudan Rifts,Central Africa显示文摘 | TIM R Mchargue TOM L Heidrick JACK E Livingston | 1992 | Tectonophysics1992，21，3： | 1 |
| 7 | Reduced polymerization stress through non -bonded nanofilled particles显示文摘 | John R Condon Jack L Ferracane | 2002 | Biomaterials2002，23，： | 1 |
| 8 | Mannose-binding lectin regulates the inflammatory response of human professional phagocytes to Nsisseria meningitides serogroup B 显示文摘 | Jack D L Read R C Tenner A J | 2001 | J Infect Dis2001，184，9： | 1 |
| 9 | Tumor induction and tissue atrophy in mice lacking E2F- 1 显示文摘 | Yamasaki L Jacks T Bronson R | 1996 | Cell1996，85，： | 1 |
| 10 | Comparative mieroarray analysis and pulmonary changes in brown norway rats exposed to ovalbumin and concentrated air particulates 显示文摘 | Brooke L H David M R Jack R H | 2009 | Toxicological Sciences2009，108，： | 1 |
| 11 | Negative-sequence currents and losses in the solid rotor of a turbogenerator显示文摘 | JACK A G STOLL R L | 1980 | IEEE PROC1980，127，2： | 1 |
| 12 | Impaired microRNA processing enhances cellular transformation and tumorigenesis显示文摘 | Kumar M S Lu J Mercer K L Golub T R Jacks T | 2007 | Nat Genet2007，39，： | 1 |
| 13 | Volumetric MRI vs clinical predictors of Alzheimer disease in mild cognitive impairment显示文摘 | A S. Fleisher S Sun C Taylor C P. Ward A C. Gamst R C. Petersen C R. Jack P S. Aisen L J. Thal | 2008 | Neurology2008，，3： | 1 |
| 14 | Tumor induction and tissue atrophy in mice lacking E2F-1显示文摘 | Yamasaki L Jack T Bronson R | 1996 | Cell1996，85，4： | 1 |
| 15 | Microstructural Effects on the Thermal Conductivity Polycrystalline A- luminum Nitride显示文摘 | Jack H E Roy W R John W L | 1991 | J Am Ceram Coc1991，74，9： | 1 |
| 16 | Toll like receptor 2(TLR2) and TLR4 differentially active human dendritic cells显示文摘 | Fabio R Jack L | 2001 | J Biol Chem2001，276，37： | 1 |
| 17 | Kinetic study of the pyrolysis of waste wood显示文摘 | Theodore R N Jack B H John P L | 1998 | Ind Eng Chem Res1998，37，： | 1 |
| 18 | The effects of embeddedness on theentrepreneurial process 显示文摘 | Jack S L Anderson A R | 2002 | Journal of Business Venturing2002，，17： | 1 |
| 19 | The Effects of Em- beddedness on the Entrepreneurial Process显示文摘 | JACK S L ANDERSON A R | 2002 | Jour- nal of Business Venturing2002，17，5： | 1 |
| 20 | Evaluation of composite wear with a new multi-mode oral wear simulator显示文摘 | John R Condon Jack L Ferracane | 1996 | Dental Materials1996，12，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员