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| 1 | Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial显示文摘 | JY Douillard D Cunningham AD Roth M Navarro RD James P Karasek P Jandik T Iveson J Carmichael M Alakl G Gruia L Awad P Rougier | 2000 | The Lancet2000，，9209： | 4 |
| 2 | Predictors of disease severity in ulcerative colitis patients from Southwestern Ontario显示文摘AIM:To understand the demographic characteristics of patients in Southwestern Ontario,Canada with ulcerative colitis(UC)in order to predict disease severity. METHODS:Records from 1996 to 2001 were exam- ined to create a database of UC patients seen in the London Health Sciences Centre South Street Hospital Inflammatory Bowel Disease Clinic.To be included, patients'charts were required to have information of their disease presentation and a minimum of 5 years of follow-up.Charts were reviewed using standardized data collection forms.Disease severity was generated during the chart review process,and non-endoscopic Mayo Score criteria were collected into a composite. RESULTS:One hundred and two consecutive patients'data were entered into the database.Demographic analyses revealed that 51%of the patients were male, the mean age at diagnosis was 39 years,13.7%had a first degree relative with inflammatory bowel disease (IBD),61.8%were nonsmokers and 24.5%were ex-smokers.In 22.5%of patients the disease was limited to the rectum,in 21.6%disease was limited to the sigmoid colon,in 22.5%disease was limited to the left colon,and 32.4%of patients had pancolitis. Standard multiple regression analysis which regressed a composite of physician global assessment of disease severity,average number of bowel movements,and average amount of blood in bowel movements on year of diagnosis and age at time of diagnosis was significant,R 2=0.306,F(7,74)=4.66,P<0.01. Delay from symptoms to diagnosis of UC,gender, family history of IBD,smoking status and disease severity at the time of diagnosis didnot significantly predict the composite measure. CONCLUSION:UC severity is associated with younger age at diagnosis and year of diagnosis in a longitudinal cohort of UC patients,and may identify prognostic UC indicators. | Lee S Roth Nilesh Chande Terry Ponich Maya L Roth James Gregor | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 3 | A Laboratory Model to Evaluate Cutout Resistance of Implants for Pertrochanteric Fracture Fixation显示文摘 | Mark B. Sommers Christoph Roth H. Hall Benjamin C. C. Kam Larry W. Ehmke James C. Krieg Steven M. Madey Michael Bottlang | 2004 | Journal of Orthopaedic Trauma2004，，6： | 2 |
| 4 | Microbiology of the skin: res- ident flora, ecology, infection 显示文摘 | ROTH R R JAMES W D | 1989 | Am Acad Dermatol1989，20，3： | 1 |
| 5 | The influence of an integration strategy on competitive capabilities and business performance:An exploratory study of consumer products manufacturers显示文摘 | Rosenzweig E D Roth A V James W Dean J | 2003 | Journal of Operations Management2003，21，4： | 1 |
| 6 | BRAF Polymorphisms and Risk of Melanocytic Neoplasia显示文摘 | Michael R James Richard B Roth Michael M | | 0，，： | 1 |
| 7 | Microbial ecology of the skin 显示文摘 | Roth RR James WD | 1988 | Ann Rev Microbiol1988，42，1： | 1 |
| 8 | Ovarian Function after Uterine Artery Embolization for Leiomyomata: Assessment with Use of Serum Follicle Stimulating Hormone Assay显示文摘 | James B. Spies Antoinette R. Roth Sheila M. Gonsalves Kerry M. Murphy-Skrzyniarz | 2001 | Journal of Vascular and Interventional Radiology2001，，4： | 1 |
| 9 | Does the Timing of Esophagectomy After Chemoradiation Affect Outcome?显示文摘 | Jae Y. Kim Arlene M. Correa Ara A. Vaporciyan Jack A. Roth Reza J. Mehran Garrett L. Walsh David C. Rice Jaffer A. Ajani Dipen M. Maru Manoop S. Bhutani James Welsh Edith M. Marom Stephen G. Swisher Wayne L. Hofstetter | 2012 | The Annals of Thoracic Surgery2012，，1： | 1 |
| 10 | Segmental neurofibromatosis显示文摘 | Roth RR Martines R James WD | 1987 | Arch Dermatol1987，123，7： | 1 |
| 11 | A cohort study of one-year functional and radiographic outcomes following intra-articular distal radius fractures显示文摘 | Emily A. Lalone Vaishnav Rajgopal James Roth Ruby Grewal Joy C. MacDermid | 2014 | HAND2014，，2： | 1 |
| 12 | The Matrix Revisited显示文摘 | James Roth Donald Espersen | 2004 | The Internal Auditor2004，，8： | 1 |
| 13 | Patient Rating of Wrist Pain and Disability: A Reliable and Valid Measurement Tool显示文摘 | Joy C. MacDermid Tom Turgeon Robert S. Richards Mark Beadle James H. Roth | 1998 | Journal of Orthopaedic Trauma1998，，8： | 1 |
| 14 | Frequent Sequence Variation in the Human Myostatin (GDF8) Gene as a Marker for Analysis of Muscle-Related Phenotypes显示文摘 | Robert E. Ferrell Victor Conte Elizabeth C. Lawrence Stephen M. Roth James M. Hagberg Ben F. Hurley | 1999 | Genomics1999，，2： | 1 |
| 15 | A method for experimental, pe- nentrating gastric and duodenal uclers on rats 显示文摘 | Okabe S Jame LA Roth C J | 1971 | Diges Dis1971，16，3： | 1 |
| 16 | The matrix revisited显示文摘 | James Roth Donald Espersen | 2004 | The Internal Auditor2004，，5： | 1 |
| 17 | Alarmins: awaiting a clinical response显示文摘 | Chan James K Roth Johnnes Oppenheim Joost J Tracey Kevin J Vogl Thomas Feldmann Marc Horwood Nicole Nanchahal Jagdeep | 2012 | EN2012，，8： | 1 |
| 18 | The Effect of Legal Environment on Big Five Auditor Conservatism Around the World显示文摘 | James Roth | 2013 | University of Missouri-Columbia Working paper2013，，29： | 1 |
| 19 | Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial显示文摘 | JY Douillard D Cunningham AD Roth M Navarro RD James P Karasek P Jandik T Iveson J Carmichael M Alakl G Gruia L Awad P Rougier | 2000 | The Lancet2000，，9209： | 1 |
| 20 | Leiomyomata treated with uterine artery embolization:factors associated with successful symptom and imaging outcome显示文摘 | James B Spies Antoinette R Roth Jackeline Gomez-Jorge | 2002 | Radiology2002，222，： | 1 |
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