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| 1 | Phased,chromosome-scale genome assemblies of tetraploid potato reveal a complex genome,transcriptome,and predicted proteome landscape underpinning genetic diversity显示文摘Cultivated potato is a clonally propagated autotetraploid species with a highly heterogeneous genome.Phased assemblies of six cultivars including two chromosome-scale phased genome assemblies revealed extensive allelic diversity,including altered coding and transcript sequences,preferential allele expression,and structural variation that collectively result in a highly complex transcriptome and predicted proteome,which are distributed across the homologous chromosomes.Wild species contribute to the extensive allelic diversity in tetraploid cultivars,demonstrating ancestral introgressions predating modern breeding efforts.As a clonally propagated autotetraploid that undergoes limited meiosis,dysfunctional and deleterious alleles are not purged in tetraploid potato.Nearly a quarter of the loci bore mutations are predicted to have a high negative impact on protein function,complicating breeder’s efforts to reduce genetic load.The StCDF1 locus controls maturity,and analysis of six tetraploid genomes revealed that 12 allelic variants of StCDF1 are correlated with maturity in a dosage-dependent manner.Knowledge of the complexity of the tetraploid potato genome with its rampant structural variation and embedded deleterious and dysfunctional alleles will be key not only to implementing precision breeding of tetraploid cultivars but also to the construction of homozygous,diploid potato germplasm containing favorable alleles to capitalize on heterosis in F1 hybrids. | Genevieve Hoopes Xiaoxi Meng John P.Hamilton Sai Reddy Achakkagari Fernanda de Alves Freitas Guesdes Marie E.Bolger Joseph J.Coombs Danny Esselink Natalie R.Kaiser Linda Kodde Maria Kyriakidou Brian Lavrijssen Natascha van Lieshout Rachel Shereda Heather K.Tuttle Brieanne Vaillancourt Joshua C.Wood Jan Mde Boer Nolan Bornowski Peter Bourke David Douches Herman Jvan Eck Dave Ellis Max J.Feldman Kyle M.Gardner Johannes C.P.Hopman Jiming Jiang Walter S.De Jong Joseph C.Kuhl Richard G.Novy Stan Oome Vidyasagar Sathuvalli Ek Han Tan Remco A.Ursum M.Isabel Vales Kelly Vining Richard G.F.Visser Jack Vossen G.Craig Yencho Noelle L.Anglin Christian W.B.Bachem Jeffrey B.Endelman Laura M.Shannon Martina V.Stromvik Helen H.Tai Bjorn Usadel C.Robin Buell Richard Finkers | 2022 | Molecular Plant2022，15，3： | 4 |
| 2 | Anastomotic biliary strictures after liver transplantation: Causes and consequences显示文摘 | Robert C. Verdonk Carlijn I. Buis Robert J. Porte Eric J. van der Jagt Abraham J. Limburg Aad P. van den Berg Maarten J.H. Slooff Paul M.J.G. Peeters Koert P. de Jong Jan H. Kleibeuker Elizabeth B. Haagsma | 2006 | Liver Transpl2006，，5： | 2 |
| 3 | The association between neuroticism and self-reported common somatic symptoms in a population cohort显示文摘 | Judith G.M. Rosmalen Jan Neeleman Reinold O.B. Gans Peter de Jonge | 2007 | Journal of Psychosomatic Research2007，，3： | 2 |
| 4 | Risk of Developing Adenomas and Carcinomas in the Ileal Pouch in Patients With Familial Adenomatous Polyposis显示文摘 | Pieter Friederich Andrea E. de Jong Lisbeth M. Mathus–Vliegen Eveline Dekker Han H. Krieken Jan Dees Fokko M. Nagengast Hans F.A. Vasen | 2008 | Clinical Gastroenterology and Hepatology2008，，11： | 1 |
| 5 | A dose-finding study of methylene blue to inhibit nitric oxide actions in the hemodynamics of human septic shock显示文摘 | Nicole P. Juffermans Marc G. Vervloet Catharina R.G. Daemen-Gubbels Jan M. Binnekade Martin de Jong A.B. Johan Groeneveld | 2010 | Nitric Oxide2010，，4： | 1 |
| 6 | Understanding consumer confidence in the safety of food:its two-dimensional structure and determinants显示文摘 | JNNEKE DE JONGE HANS VAN TRIJP REINT JAN RENES LYNN FREWER | 2007 | Risk analysis2007，，27： | 1 |
| 7 | The mechanism behind microstructure formation in mixed whey protein -polysaeeharide cold-set gels显示文摘 | Saskia de Jong H Jan Klok Fred van de Velde | 2009 | Food Hydrocolloids2009，23，： | 1 |
| 8 | Long-term results of stomach-conserving therapy in gastric MALT lymphoma显示文摘 | Conny Vrieling Daphne de Jong Henk Boot Jan Paul de Boer Froukje Wegman Berthe M.P. Aleman | 2008 | Radiotherapy and Oncology2008，，3： | 1 |
| 9 | Specific determinants of intrinsic work motivation,emotional exhaustion and turnover intention:A muhi-sample longitudinal study显示文摘 | Inge Houkes Janssen P M Jan de Jonge & Bakker A B | 2003 | Journal of Occupational and Organizational Psychology2003，，4： | 1 |
| 10 | Urinary creatinine excretion, an indirect measure of muscle mass, is an independent predictor of cardiovascular disease and mortality in the general population显示文摘 | Leendert H. Oterdoom Ron T. Gansevoort Jan P. Schouten Paul E. de Jong Reinold O.B. Gans Stephan J.L. Bakker | 2009 | Atherosclerosis2009，，2： | 1 |
| 11 | Simutaneons detection of bovine Theileria and Babesia species by reverse line blot hybridization 显示文摘 | Gubbels JM de Vos AP van der Weide M Viseras J Schouls LM de Vires E Jonge jan F | 1999 | J Clin Microbiol1999，37，6： | 1 |
| 12 | Understanding Consumer Confidence in the Safety of Food: Its Two‐Dimensional Structure and Determinants显示文摘 | Janneke De Jonge Hans Van Trijp Reint Jan Renes Lynn Frewer | 2007 | An International Journal2007，，3： | 1 |
| 13 | Restoring adventitious shoot formation on chrysanthemum leaf explants following cocultivation with Agrobacterium tumefaciens显示文摘 | JAN DE JONG RADEMAKER W MONIQUE F | 1993 | Plant Cell Tissue and Organ Culture1993，32，： | 1 |
| 14 | Demonstration of rennin mRNA, angiotensinogen mRNA, and angiotensin converting enzyme mRNA expression in the human eye: evidence for an intraocular rennin-angiotensin system显示文摘 | Wagner J Jan Danser AH Derkx FH de Jong TV Paul M Mallins JJ | | Br0，，： | 1 |
| 15 | Comparing Group and Individual Level Assessments of Job Characteristics in Testing the Job Demand-Control Model: A Multilevel Approach显示文摘 | Jan De Jonge Gerard J. P. Van Breukelen Jan A. Landeweerd Frans J. N. Nijhuis | | Human Relations0，，： | 1 |
| 16 | Immune Escape of Tumors In Vivo by Expression of Cellular FLICEinhibitory Protein 显示文摘 | Joan de Jong Thorbald van Hall | 1999 | J Exp Med1999，190，7： | 1 |
| 17 | Biomass and fossil fuel conversion by pressurised fluidised bed gasifica - tion using hot gas ceramic filters as gas cleaning显示文摘 | Wiebren de Jong Omer Una Jans Andries | 2003 | Bio- mass and Bioenergy2003，25，1： | 1 |
| 18 | Structuring on-the-job training: report of a multiple case study 显示文摘 | Jong Jan A De & Bert Versloot | 1999 | International Journal of Traimng and Developmerit1999，，3： | 1 |
| 19 | Monitoring consumer confidence in food safety: an exploratory study显示文摘 | Janneke de Jonge Lynn Frewer Hans van Trijp Reint Jan Renes Willem de Wit Joke Timmers | 2004 | British Food Journal2004，，10： | 1 |
| 20 | Optimized bacterial production of nonglycosylated human transferrin and its half-molecules显示文摘 | Maarten H. de Smit Peter Hoefkens Gerard de Jong Jan van Duin Peter H. van Knippenberg Hendrik G. van Eijk | 1995 | International Journal of Biochemistry and Cell Biology1995，，8： | 1 |
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