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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | 显示文摘 | Jason C Wayne D Mader J T | 1988 | J Bone Joint Surg (Am)1988，70，： | 1 |
| 3 | Image quality of sparse -aperture designs for remote sensing显示文摘 | Robert D F Theodore A T Jason R C | 2002 | Optical Engineering2002，41，8： | 1 |
| 4 | Mi- croalgae to biofuels lifecycle assessment--multiple pathway evalua- tion 显示文摘 | Jason C Quinn Gordon T Smith Cara Meghan Downes | 2014 | Algal Research2014，4，4： | 1 |
| 5 | Recent advance in techniques for hyperspectral image processing显示文摘 | Antonio P Jon A B Joseph W B Jason B Lorenzo B Gustavo C V Jocelyn C Mathieu F Paolo G Anthony G Mattia M James C T Giovanna T | 2009 | Remote Sensing of Environment2009，113，： | 1 |
| 6 | Solvent effects on copper nanoparticle growth behavior in AOT reverse micelle Systems显示文摘 | Joanna P C Michael E M Jason B T | 2001 | Phys ChemB2001，105，12： | 1 |
| 7 | Identification and composi- tion of phenolic compounds in the preparation of oolong tea manu, factured by semifermentation and drying processes 显示文摘 | Dou J P Viola S Y L Jason T C T | 2007 | J Aric Food Chem2007，55，： | 1 |
| 8 | Learning from Programmed Instruction: Examining Implications for Modern Instructional Technology显示文摘 | JASON K MCDONALD STEPHEN C YANCHAR RUSSELL T OSGUTHORPE | 2005 | Educational Technology Research and Development2005，53，2： | 1 |
| 9 | Deposition and annealing of lead scandium tantalite thin films for high performance thermal detector arrays 显示文摘 | MIKE A T PAUL P D JASON C J | 1999 | Integrated Ferroelectrics1999，25，： | 1 |
| 10 | Longitudinal variation in muscle protein expression and contraction kinetics of largenmuth bass axial muscle 显示文摘 | TIERNEY M T JASON M B DAVID J C | 2001 | Journal of Experimental Biology2001，204，24： | 1 |
| 11 | Oil bodies and their associated proteins,oleosin and caleosin显示文摘 | Gitte I F John M Jason T C T | 2001 | Physiologia Plantarum2001，112，3： | 1 |
| 12 | Effect of sesame antioxidants on LPS-induced NO production by BV2 microglial cells 显示文摘 | Hou Rolis Chien-Wei hen Huan-Lian l zen Jason T C | 2003 | Neuroreport2003，4，14： | 1 |
| 13 | Deposition and annealing of lead scandium tantalate thin films for high performance thermal detector arrays显示文摘 | Mike A T Paul P D Jason C J | 1999 | Integrated Ferroelectrics1999，25，： | 1 |
| 14 | A quantitative tool for assessing the integrity of southern coastal California streams 显示文摘 | Peter R O Andrew C R Jason T M | 2005 | Environmental Management2005，35，4： | 1 |
| 15 | Laboratory and field performance of cellular fiber-reinforced polymer composite bridge deck systems显示文摘 | ZHOU Aixi JASON T C ANTHONY B T | 2005 | Journal of composites for construction2005，2005，： | 1 |
| 16 | BAK1, an Arabidopsis LRR Receptor-like Protein Kinase, Interacts with BRI1 and Modulates Brassinosteroid Signaling显示文摘 | Jia Li Jiangqi Wen Kevin A Lease Jason T Doke Frans E Tax John C Walker | 2002 | Cell2002，，2： | 1 |
| 17 | Late Quaternary slip rate gradient defined using high-resolution topography and Be dating of offset landforms on the southern San Jacinto Fault zone, California 显示文摘 | Blisniuk K Rockwell T Owen L A Oskin M Lippincott C Caffee M W Dortch Jason | 2010 | Journal of Geophysical Research2010，11，508： | 1 |
| 18 | Image quality of sparse-aperture designs for remote sensing显示文摘 | Robert D F Theodore A T Jason R C | 2002 | Optical Engi- neering2002，41，8： | 1 |
| 19 | Bio-mediated soil improvement显示文摘 | Jason T DeJong Brina M Mortensenb Brian C Martinez | 2010 | Ecological Engineering2010，36，2： | 1 |
| 20 | Oil bodies and their associated proteins, oleosin and caleosin 显示文摘 | Frandsena G I John Mundy Jason T C | 2001 | Physiologia Plantarum2001，112，30： | 1 |
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